medication development for the treatment of cocaine addiction progress at preclinical and clin

báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx

Ngày tải lên : 18/06/2014, 15:20

... between endothelial cells of the BBTB to enhance the permeation of drugs across the BBTB[34,47,48] The overall ineffectiveness of these approaches can be attributed to the fact that there is only ... [70-72] Novel strategy to improve the effectiveness of systemic chemotherapy The novel strategy that I propose here to improve the effectiveness of systemic chemotherapy in the treatment of malignant ... the microvasculature of early, less mature and smaller malignant brain tumor colonies is to nanometers lower than that of the BBTB of the microvasculature of late, more mature and larger malignant...

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Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf

Ngày tải lên : 11/08/2014, 14:21

... three months of treatment Between the commencement of the new psychotropic treatment regimen in October 2007 and the significant improvement of the depressive symptoms as described above, the arthritis ... the effects of mirtazapine as the patient had been treated continuously with this compound long before and after the clinical improvement This leaves us to the discussion of the anti-inflammatory ... Eyre: Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report Journal of Medical Case Reports...

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Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique

Ngày tải lên : 26/10/2012, 09:32

... direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the current study ... incapable of re-innervating the joint In this study we investigate the long-term efficacy of facet debridement for the treatment of chronic back pain originating in the facet joint MATERIALS AND METHODS ... reduction of 3.3 at six months follow-up; 40% of patients had relief for at least 12 months, and mean duration of pain relief was 14 months Barlocher et al treated 50 patients with cryorhizotomy of the...

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Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"

Ngày tải lên : 26/10/2012, 09:57

... moderate to disabling pain, with average scores of 6.7 and 24.75 on the VAS and Oswestry, respectively and the Individual patient data is presented in Table Utilizing the Student’s t-Test, the data ... Thoracic radiculopathy is rare, as evidenced by the paucity of literature regarding the appropriate management of these patients In our experience, patients with thoracic central and foraminal stenosis ... central or foraminal stenosis treated with endoscopic laminoforaminoplasty via a small incision, of less than one inch Materials and Methods Twelve patients were treated with endoscopic laminoforaminoplasty...

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Behavior of Nitrite Oxidizers in the Nitrification/Denitrification Process for the Treatment of Simulated Coke-Oven Wastewater

Ngày tải lên : 05/09/2013, 09:38

... laboratory of UT at 4oCstored Then, each of the samples were divided into two One of them was for DNA extraction and was washed with TE buffer at pH8.0, and stored at -20oC Another was for FISH ... Journal of Water and Environment Technology, Vol.5, No.1, 2007 experiment, the authors observed the accumulation of nitrite instead of nitrate in the nitrification step In an attempt to clarify the ... applied, and the condition was optimized In general, the higher concentration of primers can lead to the formation of primer dimers Also, the cost of the chemicals should be minimized if the same...

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Contact-Adsorption-Regeneration-Stabilization Process for the Treatment of Municipal Wastewater

Ngày tải lên : 05/09/2013, 09:38

... with the increased HRT of the adsorption tank From an engineering application point of view, the appropriate operational parameters of the recycle ratio, HRT of the regeneration tank, HRT of the ... I, the recycle ratio (R) and the SRT were kept at 40% (with a recycling sludge flowrate of L/h) and d, respectively, the HRT of the regeneration tank was decreased stepwise from h to h for the ... technical feasibility of this process was demonstrated The effects of recycle ratio, HRT of the regeneration tank, HRT of the adsorption tank and SRT of the system were evaluated The removal efficiency...

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Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx

Ngày tải lên : 14/02/2014, 22:20

... guide for healthcare professionals Information for people with metastatic colorectal cancer and their carers (‘Understanding NICE guidance’) Details of all the evidence that was looked at and other ... receptor (EGFR) and thus inhibits the proliferation of cells that depend on EGFR activation for growth Cetuximab is licensed in the UK in combination with irinotecan for the treatment of patients with ... models the analysis was carried out from the perspective of the NHS Data on progression-free survival for the treatment and control arms were taken from trial data, and an equal risk of death was...

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Hydroxyurea for the Treatment of Sickle Cell Disease docx

Ngày tải lên : 05/03/2014, 10:20

... that reported on the efficacy and/ or effectiveness of hydroxyurea treatment of hematologic diseases, the toxicity of hydroxyurea in the treatment of any disease, and the barriers to the treatment ... because they not provide sufficient data about the effectiveness of a medication we included case reports if they had information regarding the dose of hydroxyurea and the duration of treatment that ... an FDA indication for the treatment of patients with sickle cell disease, as well as the development of the National Heart, Lung, and Blood Institute recommendations for the use of the drug in...

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Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx

Ngày tải lên : 07/03/2014, 10:20

... hyperphosphorylation and NFT formation Summary Oxidative stress, tau hyperphosphorylation and the Ab biology of AD are all intricately linked, and considerable research data now exist to indicate that they ... promote the formation of Ab oligomers, aggregates and ﬁbrils [48,52–55] Metal mediated oligomerization of Ab may therefore contribute to the potent inhibition of synaptic transmission mediated by ... oligomerization and aggregation are relatively low, and well within the physiological ranges that could be expected within the brain The capacity for metals to facilitate this process may therefore...

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Báo cáo khoa học: A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer ppt

Ngày tải lên : 22/03/2014, 15:21

... although it raises the issue that our understanding of the PE intoxication pathway can be complicated by the use of recombinant immunotoxins Much of the information accumulated over years of study concerns ... changing the number of receptor sites per cell to altering the rate of internalization of the receptor or influencing the intracellular trafficking The proteome of the target cell also influences the pathway ... propose that the strategy of epitope elimination offers the best promise for the deimmunization of PE-based RITs Other potential strategies to avoid immunogenicity have a more uncertain forecast...

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Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc

Ngày tải lên : 28/03/2014, 14:20

... outcome of physical therapy? What is the optimal period of treatment and number of treatments? What is the effectiveness of physical therapy in clinical practice settings and can the findings in the ... evidence for the optimal period of treatment and number of treatments? We found evidence for the efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis of the ... information for consumers not only because of the implications for their time commitment and motivation but also because of the cost More precise information about the length of treatment and...

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Best Practice Policy Statement on Cryosurgery for the Treatment of Localized Prostate Cancer pptx

Ngày tải lên : 28/03/2014, 23:20

... Statement on Cryosurgery for the Treatment of Localized Prostate Cancer The supporting systematic literature review and the drafting of this document were conducted by the Cryosurgery for Treatment ... by the PGC and the Board of Directors of the AUA Funding of the Panel and of the PGC was provided by the AUA, although Panel members received no remuneration for their work Each member of the ... documentation The real-time measurement of tissue temperature at critical locations within and proximal to the prostate provides the urologist with an important indication of the status of the freezing...

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SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE

Ngày tải lên : 12/05/2014, 17:14

... choice and loading of the NM is a compromise between the required efficiency of the converter and the market price of the NM However, the application of noble metals for the treatment of exhaust ... in the full integration of the catalyst into the emission control system The catalyst has become integral in the design strategy for vehicle operation [43] 1.3 Catalyts for the exhaust gas treatment ... by the nature of catalysts The greater the number of carbon atoms in a molecule the higher the pre-exponential factor and the activation energy for high conversion The regularity holds both for...

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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf

Ngày tải lên : 18/06/2014, 15:20

... Cambridge, MA) for thirty minutes Isolated VLC were washed and incubated with 10% human serum or heat inactivated serum at 37°C for one hour (human serum was inactivated by incubating at 60°C for thirty ... throughout the assay, an aliquot of untreated VLCs were maintained in culture for the duration of the experiment These untreated VLCs were stained for Annexin-V/PI in parallel http://www.translational-medicine.com/content/7/1/49 ... in the presence of heat inactivated Alemtuzumab, 75% of VLC were eliminated in the presence of fresh Alemtuzumab (Figure 3B(1) and 3C) This was associated with a proportionate increase in the...

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Báo cáo hóa học: "Adaptive robot training for the treatment of incoordination in Multiple Sclerosis" doc

Ngày tải lên : 19/06/2014, 08:20

... However, no one did, and in fact the task was well tolerated Furthermore, there was no degradation of performance at the end of the adaptation phase as compared to the final portion of the wash-out phase ... (after the rest period - day 28) and T3 (after sessions - day 42) We looked at both specific differences in the two treatments and at the overall effect of robot treatment over the whole duration of ... covariate This adjustment allows us to reduce the observed variation between the two groups of subjects caused not by the treatment itself but by variation of the clinical scale at the beginning of...

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$báo cáo hóa học:" Is tension band wiring technique the "gold standard" for the treatment of olecranon fractures? A long term functional outcome study" docx$

báo cáo hóa học:" Is tension band wiring technique the "gold standard" for the treatment of olecranon fractures? A long term functional outcome study" docx

Ngày tải lên : 20/06/2014, 01:20

... Research 2008, 3:9 Statistics The microsoft excel program was used for the creation of the graphs and the SPSS program 12.0 (SPSS Inc, Chicago, IL, USA) for the creation of statistics Data analysis was ... improve the biomechanical properties of the technique [20] Rowland and Burkhart [21] gave an emphasis on the mathematical need to put the transverse hole for the figure -of- eight tension band wire ... function and minimal loss of physical capacity The technique remains the "gold standard" for the treatment of displaced and minimally comminuted olecranon fractures despite the introduction of new...

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báo cáo hóa học:" Long-term follow-up on the use of vascularized fibular graft for the treatment of congenital pseudarthrosis of the tibia" pdf

Ngày tải lên : 20/06/2014, 01:20

... analyzed using the MannWhitney U-test for quantitative data of the term of bone consolidation and leg-length discrepancy, and using Fisher's exact test for qualitative data of the existence of ankle ... consolidation following the first ipsilateral VFG at the age of 1.9 years old A second contralateral VFG was then undertaken for this patient at the age of 7.3 years old, and bone consolidation ... cases and contralateral VFG was applied in cases, in which one was for the initial trial of VFG, and the other was for the second trial of VFG after failure of bone consolidation in ipsilateral...

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$báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot$

báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot

Ngày tải lên : 20/06/2014, 04:20

... conception and design of data, analysis and interpretation of data, drafting the manuscript and revising it critically, KJC has contributed in conception and design of data, drafting the manuscript and ... contributed in acquisition of data and analysis and interpretation of data, and JHY has contributed in acquisition and analysis of data All authors read and approved the final manuscript References ... evaluate BMD (bone mineral density) as a routine protocol in our clinic for the treatment of osteoporosis The patients were followed with serial physical examinations and radiographs With the...

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$báo cáo hóa học:" The use of tibial Less Invasive Stabilization System (LISS) plate [AO-ASIF] for the treatment of paediatric supracondylar fracture of femur: a case report" doc$

báo cáo hóa học:" The use of tibial Less Invasive Stabilization System (LISS) plate [AO-ASIF] for the treatment of paediatric supracondylar fracture of femur: a case report" doc

Ngày tải lên : 20/06/2014, 04:20

... femur to deformity remodeling at this level The treatment of displaced supracondylar fractures of the femur depends on the age and size of the child, the site, the pattern of the fracture and its ... the literature, there is no report of the use of LISS tibial plates for the treatment of paediatric supracondylar fractures of the femur They may be considered for Conflict of interest statement ... responsible for literature review and writing the manuscript, CKL and KYC are responsible for the idea of the method of fracture fixation, operation of this patient and reviewing the manuscript...

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báo cáo hóa học:" Mid-term results of ponseti method for the treatment of congenital idiopathic clubfoot (A study of 67 clubfeet with mean five year follow-up)" pot

Ngày tải lên : 20/06/2014, 04:20

... relapse of the deformity Patient age at the time of relapse, bilateralism or unilateralism of the relapse foot, relapse foot deformity, treatment offered to relapsed foot, immediate results of the offered ... months) initiation of the treatment Side of relapsed foot Relapse Treatment offer to deformity correct the deformity Result of the Result at five Treatment year of follow up Bilateral Left Adductus ... excluded, to avoid the effect of neuromuscular imbalance on treatment results Age at the beginning of the treatment, gender, pattern of involvement of the foot, severity of the foot deformity according...

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