Ngày tải lên :
17/03/2014, 09:20
... to the metal binding environment (H6 03, H607, H6 43, D644, E6 72, H675, T7 13, D754) overlaid the corresponding residues in the PDE4B2 reference structure (H 23 4 , H 23 8 , H274, D275, E304, H307, T345 ... by caspase -3 Residues in PDE5 identified by Turko and colleagues [ 13, 14] H6 03, H607, H6 43, D644, E 7 62 , H675, T7 13, D754, Q 765 and Q779 were used for the modeling Mutations of T7 13 and H675 that ... gelsolin, nuclear changes such as ICAD and signal transduction such as MEK kinase [21 ], Mst-1 [22 ], PAK -2 [ 23 ] , PI3K/Akt [24 ], PKCf [25 ] and FAK [ 26 ] Caspase -3 and -7 cleave proteins at a 4DX3X2D1...