we apos d have thrown in paganini but we know how busy you are

we know how to create value annual report 2001 holcim

Ngày tải lên : 27/07/2014, 16:10

... Earnings per dividend-bearing bearer share 21.20 24.12 –12.1 Earnings per dividend-bearing registered share Fully diluted earnings per bearer share Fully diluted earnings per registered share Shareholders’ ... Gross dividend per registered share 1.00 1.00 – Dividend yield per bearer share in % 1.4 1.0 – Dividend yield per registered share in % 1.4 0.9 – Bearer share high 403 455 – Registered share high ... streamlined Romania and Bulgaria However, decreasing sales due We made further attempts at consolidation in the to lower demand coupled with one-time restructuring year under review This underlined...

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Báo cáo y học: "Glucocorticoids: do we know how they work" pot

Ngày tải lên : 09/08/2014, 03:24

... by direct binding to DNA elements (GREs) or by binding to other transcription factors (tethering) GRE-regulated and NF-κB/AP-1-regulated promoters are shown schematically with single binding ... transcriptional interference and (2) by inhibiting MAP kinases The left side represents glucocorticoid (G) combining with its receptor (GR) and inducing gene expression by binding to DNA glucocorticoid response ... Transcriptional interference is due to the liganded GR directly binding the transcription factors activator protein-1 and nuclear factor-κB and inhibiting their action (2) Glucocorticoid-induced genes,...

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Báo cáo y học: "Lessons from dynamic cadaver and invasive bone pin studies: do we know how the foot really moves during gait" potx

Ngày tải lên : 10/08/2014, 21:23

... in a dynamic model BMC Musculoskelet Disord 2007, 8(8):80 Nester CJ, Liu AM, Ward E, Howard D, Cocheba J, Derrick T, Patterson P: In vitro study of foot kinematics using a dynamic walking cadaver ... local infiltration of anaesthesia There are clear post study protocols for weightbearing and medical support Results and discussion What have we learnt about foot and ankle kinematics? A key finding ... http://www.jfootankleres.com/content/2/1/18 Additional material Do we know how the foot really moves during gait? Recent dynamic cadaver and invasive kinematic research has provided some useful insights The rearfoot...

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b. Was c. Had d. Have b 22. "Did Susan use to be your next-door neighbor?" "Yes, but I potx

Ngày tải lên : 18/06/2014, 17:20

... a had b wished c done d made a 50 Since his father .……… , his eldest brother has looked after him a death b dead c dying d died d Test 48 Pronunciation a pardon b hard c park d parent > d a ... too kind b kind enough c as kind d so kind b 20 You 'd better put our appointment in your ……… a agenda b diary c calendar d directory b 21 My parents are always with each other a annoying b ... on d taking on a 24 She has …… a lot of money in her new job a gained b earned c found d done b 25 He finished the book and watched TV a read b to read c reading d reads c 26 Would you ……...

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Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"

Ngày tải lên : 31/10/2012, 15:34

... predicted values according to height, which were calculated in a linear regression model including VC, FEV1 and PEF and individual heights The other “standard” confounding factors for lung function ... COPD In this population study, 3034 female subjects were included and 1.2% was found to have severe and 6.2% had mild COPD 16.1% had only respiratory symptoms at baseline The survey showed that ... measured with the subjects wearing only briefs Body mass index (BMI) was calculated by dividing body weight in kg by m² of body height Mental stress in 1968-1969 was defined as one or several more...

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Tài liệu www.it-ebooks.info.www.it-ebooks.info.www.it-ebooks.infoOffice 2010THE MISSING MANUALThe book that should have been in the box®ˇDownload from Wow! eBook .www.it-ebooks.infoDownload from Wow! eBook .www.i docx

Ngày tải lên : 17/02/2014, 15:20

... dding Multimedia and Movement 625 A Putting Media Clips in a Presentation Adding Video from Your Hard Drive Adding Video from a Website Adding Animated Clip Art Adding ... Word, you ll find it here Opening Word You can open Word in several different ways, depending on how you installed it, but the most common method is clicking the lower-left Windows Start button ... Sound intimidating? It shouldn’t With chapters on building and linking tables, and on how to sort, search, and filter everything you ve collected, you ll have a database running in no time introduction...

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Tài liệu nanotechnology nanomaterials are widely used in commerce but epa faces pptx

Ngày tải lên : 21/02/2014, 14:20

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RAN D OM WALK IN RANDOM AND NO N- RAND OM ENVIRONMENTS h E C D N D E D I T I O N pdf

Ngày tải lên : 06/03/2014, 19:20

... appear in your subject and your book is going t o be outdated If you write a monograph on a very well-developed subject in which nothing new happens, then it is going t o be outdated already when ... results in the language of Rademacher functions The gambler will talk about coin tossing and his gain And a probabilist will consider independent, identically distributed random variables and the ... told me that he had been surprised to see how many interesting, unsolved problems had appeared in the last few years about the very classical problem of coin-tossing (random walk on the line) In...

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Báo cáo khoa học: Structural diversity in lipopolysaccharide expression in nontypeable Haemophilus inﬂuenzae Identiﬁcation of L-glycero -D-manno-heptose in the outer-core region in three clinical isolates potx

Ngày tải lên : 08/03/2014, 08:20

... study The Swedish NMR centre (Goteborg, Sweden) is acknowledged for ¨ providing access to their 600 MHz facilities Mary Deadman, Shannon Walsh and Gaynor Randle are acknowledged for culturing ... ion mass distinction between reducing, nonreducing and internal fragments resulting from the bond ruptures [27], the topology could be determined for all compositions found in the MS proﬁling spectrum ... 2 3 ND ND 1 3 3 ND ND Glycoform Relative abundanceb p 1209 1233 High Low Low Medium Medium – High – Medium Medium High High Medium Medium Medium Medium Medium Low Medium Medium Medium Medium...

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Báo cáo khoa học: Lep d 2 polymorphisms in wild and cultured Lepidoglyphus destructor mites pdf

Ngày tải lên : 17/03/2014, 09:20

... not surprising However, individual differences between patients in cytokine responses could be detected In this study, we discovered new variants of Lep d and found differences in the frequency ... inhibition ELISA inhibition of IgE-binding to Lep d 2.0101 (A and C), and Lep d 2.0102 (B and D) on solid phase Inhibition curves obtained with Lep d 2.0101 (s), Lep d 2.0102 (h) as indicated in the ﬁgure ... used in A and B and serum no in C and D Table Concentrations (lgÆmL-1) of the inhibiting allergen needed to reach 50% inhibition of IgE binding ELISA inhibition was performed as described in...

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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

Ngày tải lên : 17/03/2014, 10:20

... produce GDP-a -D- mannose Then, GDP-a -D- mannose is converted into GDP-4-keto-6-deoxyD-mannose by GDP-a -D- mannose 4,6-dehydratase (Gmd) GDP -D- rhamnose is then produced from GDP-4-keto-6deoxy -D- mannose ... short-chain dehydrogenase/ reductase family [41] In addition, both the tld and rmd gene products contain an NAD-binding domain, GXXGXXG, located near the N-terminus The tld gene product can utilize ... Coupling constant J (Hz) (s) (d) (dd) (dd*) (m) (d) (dd) (dd) (dd) (m) (d) J1,25.40 J2,33.40 J3,46.36 J4,51.96 talose peak in RP-HPLC, and NADH was used as the coenzyme The gmd and tld gene products...

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Báo cáo Y học: Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilis potx

Ngày tải lên : 17/03/2014, 17:20

... cultivated for days, was added to fermentation culture medium (1 L ´ 2), which consisted of D- [1-13C]glucose (2.5 gáL)1) added in place of L-glutamic acid (5 gáL)1) and D, L-malic acid (2 gáL)1) in ... After days, the seed culture medium (10 mL) was added to fermentation culture medium (1 L) in a 3-L conical ¯ask This fermentation culture medium contained 2.5±20 gáL)1 of D- glucose (9) added in ... occurrence and determination of d- aminolevulinic acid and porphobilinogen in urine J Biol Chem 219, 435±446 Beale, S.I & Castelfranco, P.A (1973) 14C incorporation from exogenous compounds into d- aminolevulinic...

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Báo cáo khoa học: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A ⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulation ppt

Ngày tải lên : 22/03/2014, 21:20

... processes, including cellular growth, differentiation, and apoptosis, in addition to its known functions in calcium and phosphorus metabolism [4–8] In the present study, we have shown that VD3 can induce ... blotting (C) Colony was treated with VD3, and apoptosis was evaluated (D) *P < 0.05, **P < 0.01, (n = 3) participated in the VD3-induced apoptosis in gastric cancer cells indicated that vitamin D ... increased after treatment with 5Aza (Fig 6D) Thus, we concluded that PTEN participated in vitamin D- induced apoptosis, and epigenetic modiﬁcations such as acetylation and DNA methylation were involved...

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Báo cáo khoa học: MicroRNAs – micro in size but macro in function Sunit K. Singh1,2, Manika Pal Bhadra3, Hermann J. Girschick2 and Utpal Bhadra4 pptx

Ngày tải lên : 23/03/2014, 06:20

... been reported to be involved in cleavage of double-stranded siRNA and miRNA Dicer was initially identiﬁed in Drosophila [34] and has been subsequently reported in humans, plants and fungi The ... reconstituted RLC maintains the endogenous RLC functional activities of dicing, slicing, guide-strand selection and argonaute (AGO)2 loading [46] Dicer interacts with the dsRNA-binding protein partner, ... that DCR1 is involved in miRNA maturation, whereas DCR2 is involved in initiation of RNAi in Drosophila [43,44] Although miRNAs and siRNAs have distinct biogenesis pathways in Drosophila, they have...

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Báo cáo khoa học: Novel isoenzyme of 2-oxoglutarate dehydrogenase is identiﬁed in brain, but not in heart potx

Ngày tải lên : 23/03/2014, 06:20

... uk/Tools/clustalw/index.html] under default parameters In- gel digestion SDS ⁄ PAGE-separated and Coomassie Brilliant Blue-stained protein bands of interest were excised and in- gel digested in an adapted manner ... again washed, dried, rehydrated using a freshly prepared digestion buffer containing 50 mm NH4HCO3 and 12.5 ngÆlL)1 of trypsin (Roche Diagnostics, modiﬁed, sequencing grade) and incubated at 37 ... isoenzymes in different preparations of brain OGDHC Samples isolated under the indicated conditions (details in Experimental procedures) were subjected to SDS electrophoresis, and the OGDH ⁄ OGDHL band...

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Báo cáo khoa học: D-Amino acids in the brain: the biochemistry of brain serine racemase potx

Ngày tải lên : 30/03/2014, 04:20

... and those involved in nucleotide binding are shown in red Residues involved in the binding to the PLP moiety are shown in blue, whereas those involved in protein–protein interaction are shown in ... coordinated and that the cation-binding site is formed by two carboxylate-containing residues, a main-chain carbonyl oxygen and three well-ordered water molecules The positions involved in the interaction ... no PDZ interactions with the C-terminal amino acid triplet of serine were crucial for binding, but instead, the interaction was established with its N-terminal 66 residues Binding of Golga3 increases...

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Báo cáo khoa học: Coexpression, puriﬁcation and characterization of the E and S subunits of coenzyme B12 and B6 dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli potx

Ngày tải lên : 30/03/2014, 15:20

... AdoCbl nor PLP could be involved in the mutant protein folding process during in vivo translation However, no signiﬁcant difference in protein solubility could be found between wild-type and ... analogues, 1,4-diaminobutane, 2,4-diamino-n-butyric acid, 4-aminopentanoic acid, and 2,5-diaminopentanol, was also examined in this study Our results show that none of them could be catalyzed by the ... The binding of PLP to D- ornithine aminomutase was investigated by equilibrium dialysis The proteins in the Micro Dialysis tube were equilibrated in various concentrations of PLP, and the binding...

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pye d. polarised light in science and nature (iop)

Ngày tải lên : 24/04/2014, 16:51

... are made from polymer resins by heat forming or other moulding techniques In these cases the strains imposed during shaping are retained or ‘frozen in and are easily revealed by viewing between ... unnoticed The actual values of retardation can be measured by superimposing a graduated ‘wedge’ of various known retardations and assessing the change in colour Such retardation wedges are often made ... paintwork Many windscreens are strengthened by being laminated instead of being heat toughened and not show these effects on polarised light Laminated screens are therefore preferable if the driver likes...

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escande d.f. stochasticity in classical hamiltonian systems.. universal aspects

Ngày tải lên : 24/04/2014, 17:18

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Báo cáo hóa học: " Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug " pot

Ngày tải lên : 20/06/2014, 01:20

... against F1L HindIII-digested, dephosphorylated IDT 715+716 PCR product and XhoI-digested, dephosphorylated IDT 717+718 PCR product were ligated to a HindIII-XhoI restriction fragment consisting ... enumerated and titers were determined for each time point and virus Determination of antiviral activity Plaque reduction assays were performed using HFF cells added to six well plates and incubated ... of the drugs tested including cidofovir (CDV), idoxuridine (IDU), and two thymidine analogs reported to require phosphorylation by the VV thymidine kinase (TK) [11] The only significant difference...

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