the pipeline of new treatments for advanced cancer prostate cancer as an example

101 Creative Problem Solving Techniques: The Handbook of New Ideas for Business

Ngày tải lên : 16/03/2014, 21:23

... to perform this task for you? There are numerous futurists and other consultants who can guide you They often bring a fresh perspective For example, they may be able to see the forest for the trees, ... increase the creativity of problem solving within an organization Learning these takes time and effort but you can master them These processes are directed at increasing creativity in all stages of ... follower Seeking to increase its dominance of the market, Steelcase has acquired a number of small, high-profile design companies It now has a line of wooden office furniture and the rights to furniture...

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báo cáo khoa học: "Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: An implementation guideline." pps

Ngày tải lên : 10/08/2014, 11:20

... responsible for the interpretation of the data; review of the draft versions of the manuscript; provision of feedback for important intellectual revisions; and review and final approval of the version ... document was then circulated to eight Canadian and American external reviewers with expertise in the clinical and methodological aspects of cancer screening and guideline development They were asked ... specifically for breast, cervical, and colorectal cancers? Methods A guideline panel was established as part of Cancer Care Ontario’s Program in Evidence-based Care, and a systematic review of the published...

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THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES SUSTAINABILITY EFFECTS OF FORMALISATION CONSIDERING HO CHI MINH CITY – VIETNAM AS AN EXAMPLE

Ngày tải lên : 24/08/2013, 18:48

... the business ideas of its actors and the demand for the goods and services they offer One of those manifold informal activities, namely the informal waste management systems is in the scope of ... richer areas and the often insufficient collection services in poor areas of the cities has led to the formation of an informal waste management sector The cities’ poor, who see waste rather as a ... description of the general conditions for SWM in HCMC, the description of the formal and informal SWM system and presents examples for the integration of informal actors in the formal waste management...

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Tài liệu Developing Culturally and Linguistically Competent Health Education Materials: A Guide for the State of New Jersey ppt

Ngày tải lên : 14/02/2014, 13:20

... for patients of all ages An Asthma Task Force was convened to develop systems approaches to improve the diagnosis and management of asthma within the health centers The Asthma Task Force developed ... in Spanish The Asthma Management Plan is a progress note form that aids the provider in selecting medication and other management methods appropriate for the patient's disease severity The Asthma ... 1) In Navajo asthma patients, perceptions of asthma and beliefs about the activity of asthma medications influence when and how often asthma medicines are taken, as well as the use of health services...

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The importance of project management in small- and medium-sized enterprises (SMEs) for the development of new products through E-collaboration docx

Ngày tải lên : 07/03/2014, 00:20

... Project management is the manner of implementation, of expertise, paraphernalia, knowledge and modus operandi to an extensive range of activities for the fulfillment of prerequisite of the specific ... concept (either for the company or for the customer) It includes all activities from the development of an idea or a concept for a product, to the realization of the product during the production ... developing new products in SMEs To understand the importance of coordinating these sections with the project manager and validated the model, the author interviewed 20 project managers The majority of...

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Research Gaps and Measurement Challenges for Studying the Influence of New Media on Adolescent Sexual Health docx

Ngày tải lên : 30/03/2014, 05:20

... the Office of the Assistant Secretary for Planning and Evaluation (ASPE) within the U.S Department of Health and Human Services The goal of the task order is to develop a working knowledge base ... “snapshot” of the past but was adequate to answer the question of how television content might influence youth In contrast, the content of online and other new media can change and can so in response ... predictions (for example, the Theory of Reasoned Action) or were too specific to account for the variety of predictions that could be made regarding new media (for example, theories of social distancing)...

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Working for independence The failure of New Deal politics in a rural industrial place

Ngày tải lên : 03/06/2014, 02:24

... Reproduced with permission of the copyright owner Further reproduction prohibited without permission Reproduced with permission of the copyright owner Further reproduction prohibited without ... permission Reproduced with permission of the copyright owner Further reproduction prohibited without permission Reproduced with permission of the copyright owner Further reproduction prohibited without ... permission Reproduced with permission of the copyright owner Further reproduction prohibited without permission Reproduced with permission of the copyright owner Further reproduction prohibited without...

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báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc

Ngày tải lên : 18/06/2014, 15:20

... sequences of the H19 gene for the development of DNAbased therapy for human ovarian cancer related ascites The successful development of anti-tumor gene therapy depends on the use of a combinatorial ... probe as control to test the specificity of the ISH The intensity of the hybridization signal was indicated as (+1) for weak, (+2) for moderate and (+3) for strong signals The distribution of the ... therapy of ovarian cancer, we determined the level of H19 transcripts in cells from ascites fluid of women patients Ascitic fluid was collected from the peritoneum of patients carrying ovarian cancer...

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Báo cáo hóa học: " Abstract Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor." ppt

Ngày tải lên : 18/06/2014, 16:20

... However, while the number of cellular therapy trials remained the same, the clear trend was towards an increase in the number of vaccine trials Perhaps the costs and the complex logistics associated ... contributions MJH and CAK conceived, outlined the direction of, and drafted the manuscript MJH, CCM and KLE refined the search for information, gathered references and generated the tables and figure ... IDH1, EGFR, and NF1 Cancer Cell 2010, 17:98-110 Huse JT, Holland EC: Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma Nat Rev Cancer 2010, 10:319-31...

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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx

Ngày tải lên : 18/06/2014, 16:20

... early studies of our group and others, the transcriptional regulatory sequences of the H19 and IGF2 genes emerged as candidates for cancer targeted therapy H19 and IGF2 (the human P3 and P4 promoters) ... relevant tool for the investigation of the biology and therapy of bladder cancer than subcutaneous implantation of bladder cancer cells (heterotopic model) Therefore, a mouse model was developed ... mice were used as control The total tumor area of each bladder was determined and the mean of the total areas was calculated for each group The Mean and SD of bladder tumor area (A) and weight (B)...

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THE UNIVERSITY OF NEW SOUTH WALES SCHOOL OF BANKING & FINANCE FINS5535 DERIVATIVES & RISK MANAGEMENT TECHNIQUES Course Outline for Fall Session 2005 pot

Ngày tải lên : 20/06/2014, 14:20

... throughout the session from the class lectures and from exercises done by the students themselves from the relevant chapters of the textbook The instructors are not in a position to hand out past test/examination ... “discipline-specific” support class can be arranged with the EDU in the Faculty Students may consult the EDU for advice and assistance with assignment writing, academic reading and note-taking, oral presentation, ... in those exchanges These materials may be accessed via the relevant web pages and the usual search mechanisms may be used to locate such sites Here are some examples of relevant exchanges: CBOT...

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Báo cáo hóa học: " The existence of fixed points for new nonlinear multivalued maps and their applications" potx

Ngày tải lên : 20/06/2014, 22:20

... by N (X) the family of all nonempty subsets of X, C (X) the family of all nonempty closed subsets of X and CB (X) the class of all nonempty closed bounded subsets of X, respectively For any A, ... Corollaries 3.1 and 3.2 all generalize and improve [5, Theorem 3.4] and the primitive Chatterjea’s fixed point theorem [3] Fixed point theorems of generalized Kannan’s type and others The following ... (3.1) Therefore, the conclusion follows from Theorem 3.1 The following result is immediate from the definition of Dp and Theorem 3.1 Theorem 3.3 Let T : X → CB (X) be a capable map Suppose that there...

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báo cáo khoa học: "Nulliparity enhances the risk of second primary malignancy of the breast in a cohort of women treated for thyroid cancer" ppsx

Ngày tải lên : 09/08/2014, 02:20

... thyroid cancer and the subsequent diagnosis of breast cancer was 5.80 ± 3.24 years Two cases of detected breast cancer occurred within years from the papillary carcinoma diagnosis and they were ... development of a SPM is becoming an actual possibility for thyroid cancer survivors For example, it is known that women treated for thyroid cancer have an increased incidence of subsequent breast cancer ... only of in situ SPM breast cancer, we observed an increased risk of invasive breast cancer Chen et al (2001) [3] and Brown et al (2008) [11] observed a higher incidence of SPM of the breast in...

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Báo cáo y học: "A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy" pptx

Ngày tải lên : 12/08/2014, 15:20

... in the evaluation of the data as well as the writing of the manuscript All authors read and approved the final manuscript The chemo-sensitivity of SCLC and breast cancer that was consistently evident ... Statistical analysis Results of viability testing and RT-PCR analyses as well as the data for human cell lines are shown as mean values ± SEM (mean of standard error) Median values ± SEM were used for ... included as test of more functional relevance An important key regulator of the apoptotic pathway such as caspase-3 was also evaluated immunohistologically to study the induction of apoptosis For the...

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Báo cáo y học: "Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies" ppsx

Ngày tải lên : 12/08/2014, 23:22

... Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 2006, 6:38-51 214 Yoo CB, Jones PA: Epigenetic therapy of cancer: past, present and future ... expression; and that this provirus can switch off the transcription of the host gene within which it has integrated or can allow the coexistence of expression of both host and viral genes Further analysis ... in the cytoplasm of quiescent T cells and recruited to the nucleus following T-cell activation The relevance of these (and other) transcription factors in a potential therapeutic strategy based...

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Báo cáo y học: "Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer" potx

Ngày tải lên : 13/08/2014, 23:20

... ture of RITA and to improve the activity of a new family of potent anti -cancer drugs Conclusion The aim of the present study was to support the viability of the multi-target approach in the design ... cleft, which increases its effectiveness and makes it a lead compound for further anti -cancer drug design efforts As mentioned in the introduction, RITA was previously found to bind to the p53 tumor ... these compounds would compensate their therapeutic deficiencies because of the dynamic nature of the targets involved and the observed promiscuity of MDM2 over p53 Thereby, RITA could serve as...

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An investigation into the usefulness of the techniques for guessing the meaning of new words through context for the 11th form students at Phuc Thanh High Schoo

Ngày tải lên : 28/03/2015, 09:40

... meaning of the foreign word and that of the word in the reader's mother tongue, the extent to which the word-form and the meaning bear with each other, and the frequency of the equivalent word in the ... word and see if the passage is any way altered If not, then the substitution can serve as an acceptable paraphrase and the reader can move on In the end, there is always the dictionary, which can ... Only 8% of them said that they always consulted a dictionary when they wanted to know the meaning of new words Asking the teacher was also a good way to get the meaning of unknown words for the students...

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Development of new methodologies for the synthesis of enantiomerically enriched compounds

Ngày tải lên : 16/09/2015, 08:30

... the synthetic value of this protocol was demonstrated on the synthesis of an important precursor in Grahamimycin A, an excellent anti-bacterial and anti-fungal natural product Of the many methods ... is an attractive starting point for the synthesis of chiral auxiliaries since both enantiomeric forms are available and are reasonably cheap The abundance, crystallinity and manifold transformations ... created, the disaster could be prevented.2 Many biologically active natural products can be synthesized by the general routes of asymmetric synthesis Among many of such transformations, asymmetric...

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Assessment of the Use of Hand Warmer for Nitrate Retardation in Porous Media

Ngày tải lên : 05/09/2013, 10:15

... increase of the amount of HWCs while there is a slight change of the peak concentration in Andisol (Fig (b)) except for the more pronounced tailing of the BTCs with the increase of HWCs The peak ... bottom of the column to keep the moisture content inside the column uniform while water was sprinkled over the top of the medium until the outflow from the bottom of the column equaled the volume of ... concentrations for Andisol are lower than those for silica sand This is because the degree of the solute dispersion in Andisol is larger due to the difference between the soil properties such as the uniformity...

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