transport metabolism an interesting tool to screen insulin resistance refine diagnosis of type 2 diabetes understand disease mechanisms and or evaluate new therapies

Probiotics as a novel approach to modulate incretins, insulin secretion and risk factors of type 2 diabetes and complications

Ngày tải lên : 19/11/2015, 16:47

... On one hand insulin resistance of adipose tissue insulin resistance and elevated lipolysis increase levels of circulating FFA and thereby contribute to the development of insulin resistance as ... peripheral insulin resistance (Michael et al., 20 00; Takamura et al., 20 12) Metabolic and environmental factors affecting insulin resistance The link between elevated lipid levels and insulin resistance ... inflammation, and lifestyle factors including dietary habits and physical activity also contribute to the development of insulin resistance and subsequently to type diabetes Adiposity contributes to T2D...

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Guide to Living with Diabetes Preventing and Treating Type 2 Diabetes— Essential Information You and Your Family Need to Know ppt

Ngày tải lên : 15/03/2014, 12:20

... 168 176 184 1 92 200 20 8 21 6 22 4 23 2 24 0 27 9 319 6'4" 156 164 1 72 180 189 197 20 5 21 3 22 1 23 0 23 8 24 6 28 7 328 BMI 19 20 21 22 23 24 25 26 27 28 29 30 35 40 Key: Underweight (less than 18.5) Healthy ... 147 154 1 62 169 177 184 191 199 20 6 21 3 22 1 25 8 29 4 6'1" 144 151 159 166 174 1 82 189 197 20 4 21 2 21 9 22 7 26 5 3 02 6 '2" 148 155 163 171 179 186 194 20 2 21 0 21 8 22 5 23 3 27 2 311 6'3" 1 52 160 168 ... 197 23 0 26 2 5'9" 128 135 1 42 149 155 1 62 169 176 1 82 189 196 20 3 23 6 27 0 5'10" 1 32 139 146 153 160 167 174 181 188 195 20 2 20 9 24 3 27 8 5'11" 136 143 150 157 165 1 72 179 186 193 20 0 20 8 21 5 25 0 28 6...

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Báo cáo y học: " Barriers and facilitators to evidence based care of type 2 diabetes patients: experiences of general practitioners participating to a quality improvement program" ppt

Ngày tải lên : 11/08/2014, 05:21

... of type diabetes patients' adherence to treatment: A qualitative analysis of barriers and solutions BMC Fam Pract 20 05, 6 :20 Ajzen I: The theory of planned behaviour Organizational Behavior and ... reported a major improvement in their diabetes care According to the theory of planned behavior, decisions are made according to personal models and beliefs about the changes about to be made, and ... Grol et al., 20 04 [25 -27 ] Methods We conducted this qualitative research to acquire a better understanding of the barriers to high-quality diabetes care and into the mechanisms of change that eventually...

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management of type 2 diabetes focus on insulin therapy

Ngày tải lên : 12/08/2014, 20:58

... International Diabetes Center Insulin Use in Type Diabetes • Insulin utilized to overcome both relative insulin deficiency and insulin resistance • Purpose of insulin regimen is to mimic normal insulin ... • Insulin secretion – Beta-cell decompensation • Insulin – Types of Insulin (Basal and Bolus) – Action times – Insulin Analogs • Insulin Regimens – Rationale for selecting certain types of insulin ... needs 30 20 10 Basal Insulin Needs 0 10 12 14 16 18 20 22 24 Time (Hours) International Diabetes Center Insulins Types Examples Bolus (Meal) Insulin Rapid-acting Short-acting Insulin lispro, Insulin...

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Báo cáo khoa học: Immunonanoparticles ) an effective tool to impair harmful proteolysis in invasive breast tumor cells docx

Ngày tải lên : 23/03/2014, 07:20

... thank to Professor Roger Pain for critical reading of the manuscript and Professor Cornelius Van Noorden for providing the ﬂuorogenic substrate Z-Arg-Arg cresyl violet Surface plasmon resonance ... activity: essential role of protease inhibitors as guardians and regulators Curr Pharm Dis 8, 1 623 – 1637 Brigger I, Dubernet C & Couvereur P (20 02) Nanoparticles in cancer therapy and diagnosis Adv Drug ... hormone receptor and Her2 ⁄ neu-overexpressing phenotypes Hum Pathol 37, 121 7– 122 6 Moll R (1994) Cytokeratins in the histological diagnosis of malignant tumours Int J Biol Markers 9, 63–69 Nori...

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Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx

Ngày tải lên : 19/02/2014, 16:20

... Table CCK-8 and caerulein bind to CCK receptors [ 42] There are two types of CCK receptor, CCK1 and CCK2, differing in anatomical locations and actions [43] The sequences of the CCK receptors are ... Neoplasia 7, 22 5 25 2 23 Simpson KJ & Nicholas KR (20 02) The comparative biology of whey proteins J Mammary Gland Biol Neoplasia 7, 313– 326 24 Goldman AS (20 02) Evolution of the mammary gland defense ... core domains and is asynchronously expressed during lactation J Biol Chem 27 5, 23 074– 23 081 22 Oftedal OT (20 02) The mammary gland and its origin during synapsid evolution J Mammary Gland Biol Neoplasia...

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Báo cáo hóa học: " Research Article An Alternative Method to Compute the Bit Error Probability of Modulation Schemes Subject to Nakagami-m Fading" pdf

Ngày tải lên : 21/06/2014, 08:20

... function of M 4-QAM 16-QAM 64-QAM 25 6-QAM 16-PAM 32- PAM 64-PAM 128 -PAM 8×16-QAM 16× 32- QAM Detector DI multiplications 32 128 5 12 32 64 128 25 6 25 6 1 024 Detector DII divisions 2 2 2 2 2 After that, for ... obtained from (46) to (53) Results for the 16 × 32- QAM scheme for m ranging from 0.51 to 0.80 and from 1 .25 to 1.55 are presented, respectively, in Figures and Comparing Figures and 9, for the same ... Nakagami fading for diﬀerent values of m, ranging from 1 .25 to 1.55 referred to as Detector DI and Detector DII, as described in Section 7.4.1 Detector DI Considering an arbitrary M-ary modulation...

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báo cáo khoa học: " Peer chart audits: A tool to meet Accreditation Council on Graduate Medical Education (ACGME) competency in practicebased learning and improvement" docx

Ngày tải lên : 11/08/2014, 05:22

... study and participated in the design and coordination GT participated in the design and coordination and helped to perform the statistical analysis CE participated in the design and coordination of ... study designs and statistical methods to appraisal of clinical studies and other information on diagnostics and 5) use information technology to manage information and access on-line information [1] ... 17:1-8 American Diabetes Association: Standards of medical care for patients with diabetes mellitus Diabetes Care 20 03, 26 :S33-50 American Diabetes Association: Standards of medical care for patients...

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Long-term Exposure to Traffic-related Air Pollution and Type 2 Diabetes Prevalence in a Cross-sectional Screening-study in the Netherlands pdf

Ngày tải lên : 06/03/2014, 19:20

... based on symptoms and risk factors Diabetes Care 1997, 20 :491-496 14 World Health Organisation: Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: report of a WHO/IDF ... distance (Table and Figure 2) In some studies, distance to the nearest major road was dichotomized at cut-offs of 100 m or 25 0 m Table Characteristics of the total population and of participants ... the Netherlands Authors’ contributions MD, SM, UG, JD and BB substantially contributed to conception and design of the study, acquisition, analysis and interpretation of data; drafted and revised...

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Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot

Ngày tải lên : 07/03/2014, 16:20

... to insulin for phosphorylation of PKB and for glucose transport control may ultimately allow improved surgical procedures to avoid or reduce postoperative insulin resistance Insulin resistance ... B & James DE (20 00) Signalling through the insulin receptor Curr Opin Cell Biol 12, 22 2 22 8 Saltiel AR & Kahn CR (20 01) Insulin signalling and the regulation of glucose and lipid metabolism Nature ... White MF (20 02) IRS proteins and the common path to diabetes Am J Physiol 28 3, E413–E 422 ˚ 22 Stralfors P & Honnor RC (1989) Insulin- induced dephosphorylation of hormone-sensitive lipase Correlation...

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báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx

Ngày tải lên : 18/06/2014, 22:20

... purposes) Health and Quality of Life Outcomes 20 07, 5:69 http://www.hqlo.com/content/5/1/69 Table 2: Exploratory factor analyses of the 20 items of the ITAS: forced 2- , 3- and 4-factor solution after ... (10/146) 21 % (31/146) 22 ± 22 19 ± 36% (49/136)** 57% (77/136) 11% (15/136) 40% (55/136)*** 30 ± 23 *** 18 ± 6** Factor analyses Exploratory factor analyses (EFA) revealed factors with an Eigenvalue ... ± 1.1 2. 6 ± 1.1 2. 7 ± 1.1 2. 6 ± 1.3 3.3 ± 1 .2 3 .2 ± 1 .2 2.9 ± 1 .2 3.7 ± 1.0 3.5 ± 1.1 3 .2 ± 0.7 3.4 ± 1.1 54% 73% 62% 41% 70% 47% 52% 53% 23 % 61% 19% 23 % 23 % 43% 40% 27 % 59% 55% 25 % 40% Insulin- treated...

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báo cáo hóa học:" Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" pdf

Ngày tải lên : 20/06/2014, 16:20

... purposes) Health and Quality of Life Outcomes 20 07, 5:69 http://www.hqlo.com/content/5/1/69 Table 2: Exploratory factor analyses of the 20 items of the ITAS: forced 2- , 3- and 4-factor solution after ... (10/146) 21 % (31/146) 22 ± 22 19 ± 36% (49/136)** 57% (77/136) 11% (15/136) 40% (55/136)*** 30 ± 23 *** 18 ± 6** Factor analyses Exploratory factor analyses (EFA) revealed factors with an Eigenvalue ... ± 1.1 2. 6 ± 1.1 2. 7 ± 1.1 2. 6 ± 1.3 3.3 ± 1 .2 3 .2 ± 1 .2 2.9 ± 1 .2 3.7 ± 1.0 3.5 ± 1.1 3 .2 ± 0.7 3.4 ± 1.1 54% 73% 62% 41% 70% 47% 52% 53% 23 % 61% 19% 23 % 23 % 43% 40% 27 % 59% 55% 25 % 40% Insulin- treated...

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Báo cáo khoa hoc:" Applying the Stages of Change model to Type 2 diabetes care in Trinidad: A randomised trial" pptx

Ngày tải lên : 11/08/2014, 07:21

... of the UKPDS [ 12] and an audit described above which provided a mean HbA1c of 8.48% and a standard deviation (S) of the mean of 1.94% gave a sample size of 61 patients in each arm Inclusion and ... project and RGM and JMR provided guidance to the final protocol, design and implementation VAP conducted the clinical component and collected the data All authors read, contributed to, and approved ... Health Authority, Trinidad and Tobago 2Unit of Public Health and Primary Care, Faculty of Medical Sciences, St Augustine, The University of the West Indies, Trinidad and Tobago Authors’ contributions...

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báo cáo khoa học: " Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes" ppsx

Ngày tải lên : 11/08/2014, 12:20

... years [21 ] as being of functional importance [22 ] In particular, microRNAs (miRNAs) are accepted regulators of mamma lian cell phenotype [23 -25 ] miRNAs are approximately 22 -nucleotide post-transcriptional ... resistance in human T2D and provide new bioinformatic and protein level validation for our conclusions Methods We recruited 118 subjects for the study (Table 1) and the degree of insulin resistance ... insert shows the mean expression of OXPHOS probesets (±standard error of the mean) (c) Correlation plot for HOMA2 insulin resistance (IR) and MAS 5.0 normalized expression values for the OXPHOS probe...

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basal insulin therapy in type 2 diabetes

Ngày tải lên : 12/08/2014, 20:59

... to hours to hours to hours to hours to to 2 to to to 8 to 14 Flat to to to 13 to 16 13 to 20 20 24 NPH, neutral protamine Hagedorn Basal Insulin Therapy in Type Diabetes 20 1 tion of these longer-acting ... Basal insulin therapy in type diabetes: 28 -week comparison of insulin glargine (HOE 901) and NPH insulin Diabetes Care 20 01 ;24 :631– HOE 901 /20 04 Study Investigators Group Safety and efﬁcacy of insulin ... treat-totarget trial: randomized addition of glargine or human NPH insulin to oral therapy of type diabetic patients Diabetes Care 20 03 ;26 :3080 – 21 Feinglos MN, Bethel MA Treatment of type diabetes mellitus...

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Báo cáo y học: "Exogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetes" ppsx

Ngày tải lên : 14/08/2014, 07:21

... acquisition and analysis and contributed to revision of manuscript MJC and RJLF also contributed to study conception and revision of manuscript JMW was responsible analysis of data and contributed to ... infused t = 30 to 27 0 at kcal/min IV GLP-1 (1.2pmol/kg/min) or placebo infused t = to 27 0min 28 0 26 0 24 0 22 0 Glucagon (pmol/l) Placebo 20 0 GLP-1 180 160 140 0 30 60 90 120 150 180 21 0 24 0 27 0 Time ... 94:4679-4687 28 Schwart S, Kohl BA: Type diabetes mellitus and the cardiometabolic syndrome: impact of incretin-based therapies Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 20 10, 3 :22 7 -24 2...

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IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS

Ngày tải lên : 24/08/2014, 12:16

... grateful for his mentor Johnathan Tune, Ph.D., and comentor Kieren Mather, MD This thesis work was incepted and supported from the mutual collaboration and dedication of these two investigators with ... due to the route of administration and/ or species differences Furthermore, the effects of GLP-1 on coronary blood flow and vascular tone are unknown in humans and in the settings of MetS/T2DM ... utilization; i.e restoring the balance of myocardial oxygen supply and demand, are primary targets for advancing the treatment and management of obesity-related cardiovascular disease Therapies based...

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Metformin an old but still the best treatment for type 2 diabetes

Ngày tải lên : 12/07/2015, 15:49

... with the use of metformin compared with sulfonylurea Monotherapy in type diabetes Diabetes Care 20 02, 25 :22 44 22 48 27 Evans JM, Ogston SA, Emslie-Smith A, Morris AD: Risk of mortality and adverse ... years of age Diabetes Care 20 11, 34 :22 79 22 84 49 Wiegand S, Maikowski U, Blankenstein O, Bierbermann H, Tarnow P, Grutes A: Type diabetes and impaired glucose tolerance in European children and ... impaired insulin actions and neuronal insulin resistance [ 120 ] that leads to excessive generation and accumulation of amyloid oligomers, a key factor in the development of AD [ 121 ] The mechanisms of...

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KIẾN THỨC, THÁI ĐỘ, HÀNH VI VỀ CHẾ ĐỘ ĂN VÀ TẬP LUYỆN Ở NGƯỜI BỆNH ĐÁI THÁO ĐƯỜNG TYPE 2

Ngày tải lên : 21/11/2015, 12:20

... (20 05) Prevention of Type II Diabetes by Diet and Lifestyle Modification American College of Nutrition, 24 (5), pp 310-319 Baradaran, H (20 03) Assessing the knowledge, attitude, and understanding ... significant positive correlation between knowledge and attitude (r= 0 .26 , p=0.009) and between knowledge and behavior (r= 0 .26 , p= 0.007) No correlation found between attitude and behaviors (p= ... prevalence of diabetes mellitus is increasing worldwide Education for patients with diabetes plays an important role to manage this disease because improving knowledge for the diabetic patient and community...

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