the potential of stem cells in tissue engineering nicholas d evans and julia m polak

Tài liệu SURVEY OF CASE STUDIES OF THE USE OF KNOWLEDGE MANAGEMENT IN SOFTWARE ENGINEERING docx

Ngày tải lên : 16/01/2014, 16:33

... increase productivity and quality of the developed software The outcome of several of these improvement initiatives was summed up in an article in Communications of the ACM [10] Claims of order ... should be involved in designing the framework The scientic method is a lessons learned report 3.2.7 ICL Finland ICL in Finland has also made a knowledge management system The Finnish part of the ... work from other improvement initiatives in the company, they nd several indications of improvement: The estimation accuracy improved, and estimation models were more widespread in use The focus...

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Báo cáo y học: " The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice" pps

Ngày tải lên : 12/08/2014, 15:20

... role of γδ T cells in determining the magnitude of the inflammatory response to acute epithelial injury and in maintaining and repairing the epithelial barrier [16] Chen et al have found that a deficiency ... quasi-sinusoidal fashion with 150 breaths/min, a tidal volume of 0.18 ml and a PEEP of 2–3 cm H2O Methacholine (MCh) was administered via the jugular catheter in doubling doses ranging from 10 ... which again suggests that these cells may be involved in preventing damage or repairing damaged epithelial cells [13,14] Methods Animals Male C57BL/6J and TCR δ -/- (B6.129P2-Tcrd tm1Mom) mice to...

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The role of b cells in the pathogenesis of atherosclerosis 1

Ngày tải lên : 10/09/2015, 09:23

... thank many friends I made in the Immunology Programme as well as in Singapore Immunology Network (SIgN) for the help they rendered in however big or small and not to mention the light-hearted moments! ... migrant IgM+ plasma cells into the bone marrow of apoE-/- mice as well as the presence of long-lived IgM+ plasma cells using EdU/BrdU labeling These findings were further confirmed using an ldlr-/- ... transitional T1 and T2 stages before completing their development into circulating follicular B cells (CD23+CD21midIgDhi) and non-circulating marginal zone B cells (CD23CD21hiIgDloIgMhi) (Pillai and Cariappa,...

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The role of b cells in the pathogenesis of atherosclerosis 2

Ngày tải lên : 10/09/2015, 09:24

... the cell migration from the spleen to the bone marrow compartment, we administered and maintained the mice with BrdU in drinking water, and disrupted splenic humoral responses with DT administration ... when examining plasma cells in the bone marrow To begin our investigation into ASCs in the bone marrow of apoE-/- mice, we maintained apoE-/- mice with thymidine analog, BrdU in drinking water ... percentage of B220-BrdU+CD138+IgM+ plasma cells in BM of non-treated and treated ldlr-/- chimeric mice (n=3-8) Data pooled from two independent experiments (G) Quantification of total IgM in plasma of...

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The role of b cells in the pathogenesis of atherosclerosis

Ngày tải lên : 10/09/2015, 09:24

... survival and maintenance Our data showed that the BrdU-IgM+ plasma cells accumulating in the bone marrow were long-lived as the apoE-/- mice were maintained on BrdU in drinking water for a month The ... Measurement of oxLDL in plasma As discussed above, our work and reported findings have suggested oxLDL level in the plasma was increased in the late stage of the disease and also during disease regression ... ASCs in secondary lymphoid organs and bone marrow after immunization implied the migration of these ASCs into the bone marrow compartment Such study of the kinetics of ASC in secondary lymphoid...

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The potential of DABBA products in finland

Ngày tải lên : 26/09/2015, 12:40

... interested in the decision making process that undergoes family scrutiny and the roles and influences of the family members on the purchase of the products and services that are marketed to them Husband-wife ... research and careful pondering and risk taking skills There is a cost in designing and manufacturing a product and there is a cost in distributing and promoting it Cost must include all these elements ... products and influence them to better appreciate them Adequate pricing goes hand in hand with the most efficient forms of promotion: advertising and personal selling Depending on the market segment...

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báo cáo hóa học: " The impact of itch symptoms in psoriasis: results from physician interviews and patient focus groups" pdf

Ngày tải lên : 18/06/2014, 18:20

... symptomatic disease Symptoms of psoriasis include burning, stinging, inflammation, redness, itching, pain, scaling, and cracking of skin Some symptoms (itch, soreness, pain, stinging) are included ... are to adjust the conceptual framework and draft the PRO instrument; confirm the measurement model and assess other measurement properties; modify the instrument; and collect, analyze, and interpret ... Important additions to the disease model based on patient feedback included symptoms (skin cracking and dry skin), daily activities (choice of clothing, work impacts, household duties, and more laundry/replacing...

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báo cáo khoa học: " A new model for the characterization of infection risk in gunshot injuries:Technology, principal consideration and clinical implementation" pptx

Ngày tải lên : 11/08/2014, 20:21

... is a simple and reproducible method of systematic examination in the field of terminal ballistics The model permits the infiltration depth of exogenous particles leading to contamination in relation ... and MR drafted and designed the manuscript CW, MRu, NCG have been involved in drafting the manuscript NCG was involved in revising the manuscript All authors read and approved the final manuscript ... MR, MS, CW, MRu, and NCG conceived of the work and participated in its design and coordination CS and MR made substantial contributions to data acquisation and conception of manuscript CS and...

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Báo cáo y học: "The Effect of Active Warming in Prehospital Trauma Care during Road and Air Ambulance Transportation - a Clinical " pot

Ngày tải lên : 13/08/2014, 23:20

... the emergency room and active warming already in the field is considered one important part of such treatment Since the warming modalities need to be portable and easily handled by Search and ... rate and reduce cold discomfort during transportation to definitive care However, additional active warming had a beneficial effect in improving thermal comfort and indicated a small reduction of ... interpretation of data and critically revising the manuscript All authors read and approved the final manuscript 18 Acknowledgements and Funding The study was supported by the National Board of Health and...

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Báo cáo y học: "Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study" pptx

Ngày tải lên : 10/08/2014, 09:22

... formalin-fixed paraffin embedded; LMD: laser microdissection; MS/MS: tandem mass spectrometry; ISIS: in- sample internal standard; AL1A1: aldehyde dehydrogenase family, member A 1; AK1C1: aldo-keto ... acquired during a predefined short time window in the profile mode at the resolution of 30 000 in the m/ z range of 400 to 1600 The sets of acquired high-resolution MS and MS/MS spectra for peptides ... oxidation and formylation of lysine, arginine and N-terminal amino acids as variable modifications A p-value being < 0.05 was considered significant, and the score cutoff was 44 The lists of identified...

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Báo cáo y học: "Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis" pps

Ngày tải lên : 12/08/2014, 15:22

... that administration of UC-MSCs attenuated systemic inflammation in CIA in mice UC-MSCs downregulated the production of the proinflammatory cytokines TNF-a, and IL-6 in vitro and in vivo In addition, ... the decreased secretion of various inflammatory cytokines and chemokines, and the downregulated Th1/Th17 cells Furthermore, in the UC-MSCs treated mice, the expansion of Th2/Tregs and the production ... were determined MMP9 production was inhibited both in the cell-to-cell contact system and the transwell system All the data are expressed as the mean ± SD of more than three independent experiments...

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Beyond Bias and Barriers: Fulfilling the Potential of Women in Academic Science and Engineering docx

Ngày tải lên : 14/03/2014, 19:20

... Academy of Sciences, National Academy of Engineering, or the Institute of Medicine, and many of whom have dedicated great thought and action to the advancement of women in science and engineering ... Engineering, and Gender Differences in the Careers of Science, Engineering, and Mathematics Faculty (Box 1-3) The Committee on Maximizing the Potential of Women in Academic Science and Engineering ... Science, Engineering, and Public Policy formed our Committee on Maximizing the Potential of Women in Academic Science and Engineering and charged it to recommend methods for achieving that goal The...

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Báo cáo y học: "The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells" pot

Ngày tải lên : 14/08/2014, 08:20

... M ML ML ML M ML ML Dnmt 3a/3b DKO E E E E E E M ME ML ML ME ML ML L Mbd3 KO E E E E E E ME ML ML ML ML L N .D L L G9a WT E E E E E E M ML ML ML ML ML N .D G9a KO E E E E E E ML ME L ML M ML ML L ... E E E E E M M ML ML ML ML ML L Suv39 h1/h2 DKO E E E E E E M M M ML ML ML N .D L Dicer WT E E E E E E M ML M ML ML ML ML L Dicer KO E E E E E E ML ML ML ML ME ML ML L (c) (d) 0.5 Mb Msr1 Slc7a2 ... L Dnmt KO ME ME L Dnmt 3a/3b DKO ME ML L Mbd3 KO ME ML L G9a WT ME ML L G9a KO M ME ML Suv39 h1/h2 WT ME ML L Suv39 h1/h2 DKO ME L L Dicer WT ME L L Dicer KO M ML L Eed Dnmt G9a Suv39 h1/h2 Dicer...

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Transplantation of mesenchymal stem cells for the treatment of parkinsons disease in a mouse model

Ngày tải lên : 11/09/2015, 09:05

... role of innate immune system on the dopaminergic neuron degeneration in the MPTP-induced PD model Taken into consideration the important role of inflammation in PD, immune modulation would be ... 6- diamidino-2-phenylindole dihydrochloride DEPC diethyl pyrocarbonate DMEM Dulbecco's Modified Eagle Medium DMSO Dimethyl Sulfoxide DTT dithiothreitol EAE experimental autoimmune encephalomyelitis ... to understand the underlying signaling pathway(s) of MPTP-induced innate immune system activation as well as the mechanisms of MSC immune modulation INTRODUCTION CHAPTER INTRODUCTION INTRODUCTION...

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Applying macromolecular crowding to promote the expansion and adipogenic differentiation of human mesenchymal stem cells in vitro; an effect of matrix reciprocity

Ngày tải lên : 11/09/2015, 09:16

... Tsai MS, Hwang SM, Chen KD, et al 2007;Functional network analysis of the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow Stem ... 2001;Fibronectin and the alpha(5)beta(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland Endocrinology (7):32143222 100 Salasznyk RM, Klees RF, Williams ... cultured human mesenchymal stem cells from marrow Tissue Eng (4):415-428 129 Beresford JN, Graves SE, Smoothy CA 1993;Formation of mineralized nodules by bone derived cells in vitro: a model of bone...

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Laser surface structuring of biocompatible polymers films for potential use in tissue engineering applications

Ngày tải lên : 14/09/2015, 08:36

... mechanisms behind it, and the effect of the physical and chemical changes imparted during the laser irradiation • Further insight in the degradation study of PCL films by the irradiation of laser ... Extrusion, calendaring and blowing are the common industrial methods for fabricating polymer sheets and thin films [61, 62], of thickness ranging from tens to hundreds of micrometers These methods usually ... mathematical modeling of temperature-rise and heat propagation on the PCL film during the impingement of laser using different wavelengths and pulse duration was studied and compared with the actual...

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Effects of high glucose concentrations on the expression of genes involved in proliferation and cell fate specification of mouse embryonic neural stem cells

Ngày tải lên : 30/09/2015, 06:36

... can be divided into two major subgroups: Type I, or insulindependent diabetes mellitus (IDDM) and Type II, or non-insulin-dependent diabetes mellitus (NIDDM) IDDM is associated with marked deficiency ... proteins (named by merging the names of the first identified members of this family: the C elegans Sma protein and the Drosophila Mad protein) Phosphorylated Smad proteins translocate to the nucleus ... conserved bHLH domain in the amino-terminal region and, through this domain, they form a dimer and bind to the DNA (Sasai et al., 1992) Studies to date have revealed that Hes proteins inhibit...

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The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

Ngày tải lên : 25/10/2013, 05:20

... Third instar larvae and 3-day old pupae were used The main component of one of the oils was pulegone and of the other is not yet totally identiﬁed, and it is called SEM76 In space fumigation, these ... Shaaya and M Kostyukovsky 16.1 Introduction In developing countries, the post-harvest losses of cereals and other durable commodities caused by insect damage and other bio-agents range from 10 ... component in this plant, has lower mammalian toxicity as compared to the other active ITCs tested The lower toxicity makes this fumigant a promising candidate for the disinfestation of grain and dry...

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Tài liệu Final report "The Situation of Learning English for Electrical Engineering of D06k52 Students in Faculty of Foreign Language, Ha Noi University of Technology" docx

Ngày tải lên : 13/12/2013, 12:15

... using this method, researcher can investigate the common difficulties and advantages students had during the fifth term when they studied EEE Moreover, the main reason of getting bad mark in the ... of learning EEE as well as the main reason why they did not get good mark in the final test Techniques of gathering data including different types of questionnaires administered to students in ... seldom read or repair lesson before going to class They did not spend a lot of time on studying it From these facts, they could not understand all things learned in class and then, they got bad...

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Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf

Ngày tải lên : 06/03/2014, 00:20

... protein products due to translation errors and misfolding are handled by the quality control system, composed of refolding chaperones and proteases The system is energetically demanding (most ... the DnaK, DnaJ, GrpE system and the GroEL–GroES pair A comprehensive review of the folding process transcends the aim of this paper and can be found in [9,10] and references therein The folding ... formed aggregates triggering the degradation of misfolded proteins while ClpB releases them from inclusion bodies (IBs) and presents unfolded polypeptides to the (re)folding machinery Altogether,...

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