randomized placebo controlled double blind clinical trial

Báo cáo y học: "Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial" pps

Ngày tải lên : 13/08/2014, 08:20

... Vol 11 No Kluger et al severely injured trauma patients: two parallel randomized, placebo- controlled, double- blind clinical trials J Trauma 2005, 59:8-15 Dereeper E, Ciardelli R, Vincent JL: Fatal ... injured blunt-trauma patients who were included in a prospective, international, double- blind, randomized, placebo- controlled study of rFVIIa [16] and who were diagnosed by the investigators by ... of clinical scenarios [47-51] However, because of its prohemostatic activities, concerns persist over the risk for TE events during its clinical use [52] The previously mentioned randomized, controlled...

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báo cáo khoa học: " Randomized, placebo-controlled, double-blind trial of Swedish snus for smoking reduction and cessation" potx

Ngày tải lên : 11/08/2014, 18:20

... Study design This study was an investigator-initiated, randomized, multi-center, double- blind, parallel-group, placebo- controlled, phase clinical trial It focused on the potential of Swedish snus ... [21,22] The main strength of this trial was the double- blind, placebo- controlled design although the protocol did not include procedures to assess the success of the blinding The main weakness was ... Brussels; 2008 doi:10.1186/1477-7517-8-25 Cite this article as: Joksić et al.: Randomized, placebo- controlled, double- blind trial of Swedish snus for smoking reduction and cessation Harm Reduction...

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Báo cáo y học: "Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial" doc

Ngày tải lên : 09/08/2014, 01:21

... analysis of a 13-week, randomized, double- blind, placebo- controlled, multicenter study of three paliperidone palmitate fixed doses in subjects with Page of 10 schizophrenia (ClinicalTrials.gov: NCT00590577; ... 13 Lauriello J, Lambert T, Andersen S, Lin D, Taylor CC, McDonnell D: An 8week, double- blind, randomized, placebo- controlled study of olanzapine long-acting injection in acutely ill patients with ... a potential long-acting treatment for patients with schizophrenia Results of a randomized, double- blind, placebocontrolled efficacy and safety study Int J Neuropsychopharmacol 2010, 13:635-647...

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Báo cáo y học: "Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial" doc

Ngày tải lên : 11/08/2014, 15:22

... has been studied in several randomized, double- blind controlled trials using various dosing regimens [9-14] A recently completed phase trial was the first placebo- controlled study to assess paliperidone ... 234 mg on Day followed by 39 or 234 mg on Day Methods Design A 13-week double- blind, randomized, placebo- controlled phase trial (NCT#00590577) was conducted from March 2007 to March 2008 at 72 ... post-hoc analyses of a large, doubleblind, placebo- controlled trial The question of when clinicians and patients can anticipate an improvement in symptoms is integral to clinical decision-making,...

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Báo cáo y học: "Early response predicts subsequent response to olanzapine long-acting injection in a randomized, double-blind clinical trial of treatment for schizophrenia" potx

Ngày tải lên : 11/08/2014, 15:22

... This was a post hoc analysis of data from an 8-week, randomized, double- blind trial comparing multiple dosing regimens of olanzapine LAI with placebo for treatment Ascher-Svanum et al BMC Psychiatry ... volition, and preoccupation Discussion In this post hoc analysis of data from a randomized, double- blind, clinical trial of olanzapine LAI for treatment of acute exacerbation of schizophrenia, ... 11 Lauriello J, Lambert T, Andersen S, Lin D, Taylor CC, McDonnell D: An 8week, double- blind, randomized, placebo- controlled study of olanzapine long-acting injection in acutely ill patients with...

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Báo cáo y học: " Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: A placebo-controlled double-blind trial" ppt

Ngày tải lên : 12/08/2014, 14:20

... U: Therapy of acute nonpurulent rhinosinusitis with cineole: results of a double- blind, randomized, placebo- controlled trial Laryngoscope 2004, 114:738-742 Wittmann M, Petro W, Repges R, Dethlefsen ... Anti-inflammatory activity of 1.8-Cineole (Eucalyptole) in bronchial asthma: a double- blind placebo controlled trial Respiratory Medicine 2003, 97:250-256 Juergens UR, Engelen T, Stöber M, Racké ... Maslen TK: Randomised, double- blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial BMJ 2000, 320:1297-130...

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A double blind randomized placebo controlled clinical trial on the supplementation of probiotics in the first six months of life in asian infants at risk of allergic diseases effe

Ngày tải lên : 11/09/2015, 21:39

... benefit against infections iv impact on growth and safety Methods: This double- blind, placebo- controlled randomized clinical trial involved 253 infants with a family history of allergic disease ... an effective treatment for eczema in a randomized, double- blind, placebo- controlled study with 54 infants randomized to 5x109 CFU of L rhamnosus GG or placebo twice daily for weeks The most recent ... group (23%) as compared to the placebo group (46%) (Relative risk RR 0.51; 95% confidence interval CI 0.32-0.84) This double- blind, randomized placebo- controlled trial recruited 132 evaluable...

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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"

Ngày tải lên : 25/10/2012, 11:40

... This is a three-arm (5-Loxin®, Aflapin® and placebo) , randomized, double- blind, placebo- controlled, single-centre trial conducted over 90 days The trial' s primary objective was to determine the ... tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee: a randomized double blind placebo controlled trial Phytomedicine 2003; 10: 3-7 Bellamy N, Buchnan WW, Goldsmith CH, Campbell ... Alluri KV, Satish AR, Mishra S, Golakoti T, Sarma KV, Dey D, Raychaudhuri SP A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis...

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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx

Ngày tải lên : 12/08/2014, 11:22

... experiments in rodents have provided the basis for human clinical trials In a randomized, double- blind, multicenter, and controlled phase II clinical trial involving 236 patients with severe active RA, ... other clinical trials within months before enrolment Study design The study was a two-to-one, eight-center, 24-week follow-up, double- blind, double- dummy, randomized, and MTX -controlled trial ... arthritis clinical trials J Clin Epidemiol 1997, 50:757-763 22 Lehman AJ, Esdaile JM, Klinkhoff AV, Grant E, Fitzgerald A, Canvin J: A 48-week, randomized, double- blind, double- observer, placebo- controlled...

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Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx

Ngày tải lên : 09/08/2014, 10:23

... This is a three-arm (two doses of 5-Loxin® and placebo) , randomized, double- blind, placebo- controlled, single-centre trial conducted over 90 days The trial' s primary objective was to determine the ... significant beneficial effect in terms of pain relief in OA [33] In addition, a randomized, double- blind, placebo- controlled trial [34] showed that 4,000 mg milk protein concentrate per day (Microlactin™; ... tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee: a randomized double blind placebo controlled trial Phytomedicine 2003, 10:3-7 Bellamy N, Buchnan WW, Goldsmith CH, Campbell...

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Báo cáo hóa học: " Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial" pot

Ngày tải lên : 21/06/2014, 03:20

... Study overview The BOLD study is a multicenter, randomized, doubleblind, placebo- controlled trial that compared the effects of nebulized albuterol to placebo on donor oxygenation in 500 brain-dead ... large, randomized, clinical trials are feasible It is our hope that experience gained in the BOLD study will stimulate other investigators to test donor interventions in randomized, clinical trials ... Perkins GD, McAuley DF, Thickett DR, Gao F: The beta-agonist lung injury trial (BALTI): a randomized placebo- controlled clinical trial Am J Respir Crit Care Med 2006, 173:281-287 24 Mascia L, Pasero...

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Báo cáo khoa hoc:" Methylphenidate for treating tobacco dependence in non-attention deficit hyperactivity disorder smokers: A pilot randomized placebo-controlled trial" pptx

Ngày tải lên : 11/08/2014, 07:21

... tobacco dependence, we conducted a randomized, double- blind, placebo- controlled, phase II study of OROS-MPH at a target dose of 54-mg/day for weeks compared with placebo in 80 adult cigarette smokers ... disorder (ADHD) treatment on smoking cessation intervention in ADHD smokers: a randomized, double- blind, placebo- controlled trial J Clin Psychiatry 2010 Fagerstrom K, Furberg H: A comparison of the ... include a prospective randomized placebo controlled design We also used well developed behavioral interventions for smokers that we have employed effectively in many other clinical trials of pharmacotherapy...

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Báo cáo y học: " Skill execution and sleep deprivation: effects of acute caffeine or creatine supplementation - a randomized placebo-controlled trial" potx

Ngày tải lên : 11/08/2014, 23:21

... (20 total per trial) , for each of dominant and non-dominant passing sides on the first, fifth and twelve familiarisation trials 1st Trial Dominant Non-dominant 5th Trial a 12th Trial 7.3 ± 0.8 ... TC: Oral creatine monohydrate supplementation improves brain performance: a double- blind, placebocontrolled, cross-over trial Proc Biol Sci 2003, 270:2147-50 13 Atassi N, Ratai EM, Greenblatt DJ, ... compared to placebo administration (p < 0.001) In the placebo condition, passing skill performance was found to be superior in the non-sleep deprived than the sleep deprived trial (p < 0.001) Placebo...

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Báo cáo y học: "Efficacy in asthma of once-daily treatment with fluticasone furoate: a randomized, placebo-controlled trial" docx

Ngày tải lên : 12/08/2014, 14:20

... design This was a phase IIa, randomized, double- blind, parallel-group, placebo- controlled study conducted at 70 investigative sites in 16 countries around the world (clinicaltrials.gov study number ... Fluticasone furoate (FF) is a novel long-acting inhaled corticosteroid (ICS) This double- blind, placebo- controlled randomized study evaluated the efficacy and safety of FF 200 mcg or 400 mcg once ... Efficacy in asthma of once-daily treatment with fluticasone furoate: a randomized, placebo- controlled trial Ashley Woodcock*1, Eric D Bateman2, William W Busse3, Jan Lötvall4, Neil G...

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Báo cáo y học: " Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension" ppt

Ngày tải lên : 13/08/2014, 11:22

... pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized- controlled trial Acta Anaesthesiol Scand 2008, 52:65-72 Olschewski H, Rose F, Schermuly R, Ghofrani ... inotropic effect of PGI2 In clinical studies, such claims were based on load-dependent haemodynamic indices [6,36] In experimental studies conducted in pigs, supraclinical doses of intravenous ... baseline, and 1, 5, 10 and 30 minutes after stopping iloprost /placebo inhalation In the PHT group, measurements at minute after stopping iloprost/ placebo inhalation consisted only of the registration...

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Báo cáo y học: "The short-term safety and efficacy of fluoxetine in depressed adolescents with alcohol and cannabis use disorders: a pilot randomized placebo-controlled trial" potx

Ngày tải lên : 13/08/2014, 18:21

... depressed alcoholics A double- blind, placebo- controlled trial Arch Gen Psychiatry 1997, 54:700-705 Deas D, Randall CL, Roberts JS, Anton RF: A double- blind, placebo- controlled trial of sertraline ... placebo- controlled, randomized clinical trial J Am Acad Child Adolesc Psychiatry 2002, 41:1205-1215 Emslie GJ, Rush AJ, Weinberg WA, Kowatch RA, Hughes CW, Carmody T, Rintelmann J: A double- blind, ... was a single site, 8-week, double- blind, placebo- controlled study with parallel arms Eligible youths were randomized in approximately equal numbers to receive either placebo or fluoxetine during...

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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot

Ngày tải lên : 19/06/2014, 22:20

... corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial) : randomised placebo- controlled trial Lancet 2004, 364(9442):1321-1328 Page 11 of 12 (page ... placebo- controlled randomized study was designed to assess the effect of attenuating the neuroinflammatory response after TBI by administration of high-dose methylprednisolone [15] The trial was ... other groups *P < 0.05 for TBI_mAb 1379 vs TBI _placebo groups; #P < 0.05 for TBI vs sham groups; **P < 0.05 for TBI _placebo vs TBI_mAb 1379 vs placebo group (unpaired Student's t-test) 7) In...

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Báo cáo khoa học: "Stratiﬁcation, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia" doc

Ngày tải lên : 12/08/2014, 15:21

... (CHD) included in a double blind randomized clinical trial The numbers (n) indicate the number of dogs within each strata and randomized groups (G) = Gold implantation group (P) = Placebo group (R) ... dogs were followed in an open trial for another 18 months Double blinded controlled clinical trial over six months Treatment Open clinical trial Follow up18 months Completed no of dogs Drop out ... a controlled clinical trial of CHD The treatment effect for gold bead implantation is given in the blinded trial versus the open treatment trial Pain signs of canine hip dysplasia Treatment Blinded...

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Báo cáo khoa hoc:" Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren''''s Syndrome: a randomized, double-blind, placebo controlled cross-over study" potx

Ngày tải lên : 11/08/2014, 08:21

... study was to evaluate the effectiveness of LDD on clinical symptoms of SS in a randomized, double- blinded, placebo- controlled clinical cross-over trial Figure ment Stimulated saliva pH and salivary ... enter the study All the patients were women This was a randomized, double blind, placebo- controlled clinical trial, and the patients were randomized at the baseline Randomization was performed ... Res 1998, 12:12-26 Petrone D, Condemi JJ, Fife R, Gluck O, Cohen S, Dalgin P: A Double- Blind, Randomized, Placebo- Controlled Study of Cevimeline in Sjögren's Syndrome Patients With Xerostomia and...

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Báo cáo y học: "A randomized, double-blind, placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic stress disorder" pot

Ngày tải lên : 11/08/2014, 17:20

... stress disorder: a randomized, double- blind, placebocontrolled study J Clin Psychiatry 2007, 68(2):201-6 Lindley SE, Carlson EB, Hill K: A randomized, double- blind, placebo- controlled trial of augmentation ... these symptoms There is only one double- blind, placebo- controlled study of topiramate as a monotherapy in PTSD Tucker [29] conducted a 12-week, double- blind, placebo- controlled evaluation of topiramate ... worse; 6, much worse; or 7, very much worse Study design This is a 12-week randomized, double- blind, placebocontrolled clinical trial that will be conducted at the Federal University of São Paulo Hospital...

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