functional anatomy of the foot and ankle

Báo cáo y học: "Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature" pps

Ngày tải lên : 10/08/2014, 21:23

... of lesions were located on the plantar surface (62%) with on the ankle, on the dorsum of the foot, on the digit and located in the nail bed (with in the hallux and in the fifth toe nail bed) One ... (n = 1) and plastic surgery (n = 1) Nineteen of the lesions were reported on the right foot and eight on the left All male patients exhibited ALM on their right foot only The majority of lesions ... (distal) areas of the body, particularly the palms, soles and the sub-ungual areas, and its distinct radial or "lentiginous" growth phase ALM represents the rarest of the four sub-types of cutaneous...

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Báo cáo y học: " Improvement of pain and regional osteoporotic changes in the foot and ankle by low-dose bisphosphonate therapy for complex regional pain syndrome type I: a case series" pptx

Ngày tải lên : 10/08/2014, 23:22

... the high bone turnover and foot pain (VAS score of 83 out of 100) One month after the start of alendronate treatment, bone pain had fallen from a VAS score of 83 out of 100 to 30 out of 100 and ... Radiographs of the both ankles after treatment The regional osteoporotic change in the right ankle (Figure 1A) completely returned to normal, and findings were comparable to those of the left ankle ... Figure Radiographs (A) and scintigraphs (B) of the both ankles before treatment The radiograph of the right ankle showed regional osteoporotic findings at the distal tibia and fibula (white arrow)...

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báo cáo hóa học:" Negative pressure wound therapy for soft tissue injuries around the foot and ankle" ppt

Ngày tải lên : 20/06/2014, 01:20

... prospective randomized multicenter trial be undertaken to determine the merits of NPWT for the treatment of soft tissue defects of the ankle and foot However, based on the results of previous ... either a traffic accident in 12, a falling from a height in 2, and a crush injury in Wound locations were on the medial side of the ankle in cases, the lateral side of the ankle in case, and of ... reports have been issued on the application of NPWT to soft tissue defects of the extremities, abdomen and chest [5,6] However, reports regarding its use in the foot and ankle region are limited,...

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Báo cáo hóa học: "Hypertrophy of the feet and ankles presenting in primary hypertrophic osteoarthropathy or pachydermoperiostosis: a case report" docx

Ngày tải lên : 21/06/2014, 19:20

... wrinkling of facial features including the forehead and the nasolabial folds, with profound hypertrophy of the eyelids (30% to 40% of cases) and cutis verticis gyrata (24% of cases) [6] The combination ... medical photography, the literature search and the writing of the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they have no competing ... cardiopulmonary diseases and malignancies PDP was first reported in 1868 and it was then thought to be an example of acromegaly The Figure Hypertrophy of his feet and ankles with edema first to...

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Báo cáo y học: "Development of a practical guide for the early recognition for malignant melanoma of the foot and nail unit" potx

Ngày tải lên : 10/08/2014, 21:24

... Bristow and de Berker Journal of Foot and Ankle Research 2010, 3:22 http://www.jfootankleres.com/content/3/1/22 patient and practitioner than one on the foot Furthermore, lesions between the toes, ... for the early recognition for malignant melanoma of the foot and nail unit Journal of Foot and Ankle Research 2010 3:22 Submit your next manuscript to BioMed Central and take full advantage of: ... education [65] The authors reviewed these papers looking for common themes, key messages and learning points The focus of such papers was often around misdiagnosis, delay and deterioration of the lesion...

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Báo cáo y học: "Clinical guidelines for the recognition of melanoma of the foot and nail unit." doc

Ngày tải lên : 10/08/2014, 21:24

... et al Journal of Foot and Ankle Research 2010, 3:25 http://www.jfootankleres.com/content/3/1/25 relevance of UV light on non-exposed areas such as the plantar surface of the foot the role is not ... of malignant melanocytes within the basal layer of the epidermis, giving rise to the term “lentiginous” The term “acral” defines the location which is of the extremities, namely the skin of the ... Bristow et al Journal of Foot and Ankle Research 2010, 3:25 http://www.jfootankleres.com/content/3/1/25 Page of 13 Figure Various presentations of melanoma on the skin of the foot Assessment It...

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Báo cáo y học: " Foot and ankle surgery in Australia: a descriptive analysis of the Medicare Benefits Schedule database, 1997–2006" potx

Ngày tải lên : 10/08/2014, 21:23

... (1997–2006), and; (iii) the total cost to Medicare of subsiding foot and ankle surgeons' fees in 2006 To simplify the interpretation of the results, item numbers relating to a similar region of the foot ... nevertheless a useful resource for exploring the epidemiology and healthcare costs of surgical procedures [10] (ii) foot and ankle trauma: including treatment of dislocations and fractures of the ... 47678); The aim of this study was to investigate patterns of foot and ankle surgery provision in Australia, with particular reference to: (i) the influence of age and sex on the type of surgery...

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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

Ngày tải lên : 15/02/2014, 01:20

... II The hood domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus (Fig 1A) The ... Lys173 interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in ... Asp142, 2¢ and 3¢OH of the ribose and three water molecules with ˚ coordination distances of approximately 2.4 A The phosphate of the GMP is hydrogen bonded to main chain and side chain atoms of amino...

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Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc

Ngày tải lên : 18/02/2014, 18:20

... a4-helix to the b4 strand and the b9 strand to the b10 strand at the bottom of the Zn-stem loop in the pRN1 prim–pol structure However, because the Zn-stem loop is a fairly self-standing structure ... 70 and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of nm Thermal stability of Rep245 was measured by incubating the protein at 60, 70 and 80 °C for 30 and then ... the two-metal-ion mechanism of both RNA and DNA synthesis [17] In a previous study, we reported the ﬁndings of an analysis of the complete sequence of the cryptic plasmid pIT3 isolated from the...

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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Ngày tải lên : 21/02/2014, 15:20

... the C-terminal domain of apoCII interacts with the interface of the N- and C-terminal domains of LPL and part of the lid surface [32] Because the functional importance of LPL’s C-terminal domain ... illustrates the overall saddle shape of the dimeric structure and the key heparin-binding residues in the N-terminal domain held coordinately by the two subunits on the top of the hollow (Fig 1A) The ... not the lipase activity and that the normal afﬁnity of these mutants for heparin (Fig 3, Table 1) implies conservation of the overall structure of the WW and WWW mutants – indicate that these...

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Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

Ngày tải lên : 07/03/2014, 12:20

... interaction of the membrane-bound AAA complex and the importomer Therefore, the protein complexes isolated with protein A fusions of Pex1p, Pex6p and Pex15p were tested for the presence of peroxins of the ... contaminate the eluates (Fig 3A and data not shown), thereby confirming the specifity of the isolation Taken together, these data indicate a close association of the membrane-bound AAA complex and the ... Moreover, these data indicate that at least one of the contact sites of the AAA complex and the importomer is made by Pex15p To investigate the influence of individual peroxins of the importomer on the...

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Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx

Ngày tải lên : 07/03/2014, 16:20

... to the cytosol Here we conﬁrm and extend earlier studies of these AAA-peroxins and give a further detailed functional analysis of their cassette structure and interaction The interaction of Pex1p ... of Pex1p and Pex6p A B Fig Two-hybrid interaction of Pex1p and Pex6p harboring point mutations of the WalkerA and B motifs of their ATP-binding sites A schematic representation of the Pex1p and ... the binding sites of these two AAA-proteins to their different protein regions and elucidated the importance of ATP-binding to the two AAA-cassettes of Pex1p and Pex6p for their interaction The...

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Báo cáo Y học: Functional reconstitution of the HIV receptors CCR5 and CD4 in liposomes pot

Ngày tải lên : 08/03/2014, 09:20

... on the one hand and lipid membranes with little incorporated protein on the other [48] The success of this method thus probably depends on the relative afﬁnities of interaction of the protein and ... was present on the surface of transfected cells, and had the expected molecular mass To test whether the presence of the myc-his tag at the C-terminus of CCR5 would interfere with the protein’s ... glycosaminoglycans [37] As the myc-his tag of the protein was present at the C-terminus of the receptor which is located on the inside of the cell, we then determined if signal transduction by the protein was...

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Báo cáo khoa học: Conformational and functional analysis of the lipid binding protein Ag-NPA-1 from the parasitic nematode Ascaridia galli potx

Ngày tải lên : 16/03/2014, 18:20

... of the medium and K2 the orientation factor, determined by the mutual spatial orientation of the transition dipole moments of the donor and acceptor As no data on the spatial orientation of the ... in cells of the inner hypodermis and the epithelium of the oviduct as well as extracellularly in the pseudocoelomic cavity of the worms Discussion A bundle of four a-helices constitutes the secondary ... determined pI of 6.1 and the theoretically deduced pI value of 6.22 was found A theoretical prediction of the secondary structural organization of Ag-NPA-1 performed on the basis of the amino acid...

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Báo cáo khoa học: Molecular cloning and functional expression of the human sodium channel b1B subunit, a novel splicing variant of the b1 subunit potx

Ngày tải lên : 16/03/2014, 23:20

... signiﬁcantly in the presence or absence of the b1B subunit, whereas, under the same conditions, the rate of inactivation was increased in the presence of the b1 subunit The effects of b1B were further assessed ... in Fig 4A–D, the rates of activation and inactivation of the sodium current via 4768 N Qin et al (Eur J Biochem 270) Ó FEBS 2003 Fig The eﬀect of b1B and b1 subunits on the function and expression ... part of intron adjacent to exon (Fig 1C and Table 1) As the site of divergence between the b1 and b1B subunit cDNAs was located precisely at the exon 3/intron boundary of the SCN1B gene, the human...

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Báo cáo khoa học: Functional expression of the quinoline 2-oxidoreductase genes (qorMSL) in Pseudomonas putida KT2440 pUF1 and in P. putida 86-1 Dqor pUF1 and analysis of the Qor proteins doc

Ngày tải lên : 17/03/2014, 10:20

... from Hanes plots Determination of the metal contents of the Qor proteins, and detection of the nucleotide moiety of the molybdenum cofactor The contents of molybdenum and iron were determined by ... cleaves 364-bp upstream of the start codon of qorM, and DraIII, that cleaves 8-bp downstream of the stop codon of qorL After removing the 3¢ overhang and ﬁlling the 5¢ overhang of the plasmid with T4 ... indicated in Fig 4B The absence of Mo(V)signals reveals the g2-component of FeSII It is noted that the g-factors of the FeSI and II signals of the Qor proteins from the wild-type strain and from P putida...

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Báo cáo Y học: Functional analysis of the rat bile salt export pump gene promoter Regulation by bile acids, drugs and endogenous compounds potx

Ngày tải lên : 17/03/2014, 23:20

... further uptake and preserving or enhancing their excretion The discovery of bile acids as ligands of the orphan liver receptor FXR [14] led to the concept of FXR-mediated regulation of Ntcp and Bsep ... Analysis of the 5¢ flanking region sequence of the Bsep gene A total of 2488 bp upstream from the 5¢-end of the Bsep cDNA was sequenced in both directions; 1583 bp are shown in Fig Identity with the ... even below that of the wild-type p-126 Luc Analysis of the binding affinity of the putative FXRE site for the orphan nuclear receptor FXR To characterize the FXRE site identified in the Bsep promoter...

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Báo cáo khoa học: Functional aspects of the solution structure and dynamics of PAF – a highly-stable antifungal protein from Penicillium chrysogenum pdf

Ngày tải lên : 29/03/2014, 23:20

... activity of PAF Differences and similarities between the structures of PAF and AFP The common geometrical arrangement of the two proteins is the special Greek key fold, in which the Structure and ... mPAF at the respective concentrations of and 100 lgỈmL)1 Fig Ribbon diagram of the mean PAF structure without disulﬁde bond constraints the core of the protein (Fig 9) As a consequence of the highly-twisted ... contributing to the sheet stabilization (Table 2) The b5 strand is the most negativelycharged region of PAF and close to the C-terminus starts at Ala51 Loop (47–50) connects strands b4 and b5 and creates...

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Báo cáo hóa học: " Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic " ppt

Ngày tải lên : 18/06/2014, 16:20

... found in the father or the mother of 30 of these 125 HCM-patients, that could thus be regarded as familial cases In 45 patients, none of the parents were available for study A total of 40 of the 245 ... measured, and the left ventricular wall thickness (LVWT) calculated as the sum of IVS and PWT Table summarizes the main characteristics of patients All them fulfilled the next inclusion criteria: they ... of 150 of these controls were examined through electrocardiography to exclude the existence of cardiac diseases All the patients and controls were Caucasians from the Northern Spain regions of...

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báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt

Ngày tải lên : 20/06/2014, 07:20

... follicles were cut open and the theca and adherent granulosa cells peeled from the stroma The granulosa cells were then gently scraped from the theca and the granulosa and theca cells were snap ... [21,22] The objectives of the studies reported here were to examine the interactions of the gonadotrophins and IGF with the Akt and Erk signalling pathways in theca and granulosa cells in vitro and ... concentration of 50 μM of the inhibitors, and 50 μM (0.005%) of the DMSO Concentrations of the inhibitors were based on the treatments used in vitro in Experiment The ewes recovered from surgery and 48...

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