false positives in outwelling studies avoiding pitfalls in stable isotope gradient analysis

Báo cáo y học: "Bench-to-bedside review: Avoiding pitfalls in critical care meta-analysis — funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy" ppsx

Ngày tải lên : 13/08/2014, 11:22

... meta-regression with individual patient data meta -analysis J Clin Epidemiol 2002, 55:86-94 33 Chalmers I: The Cochrane collaboration: preparing, maintaining, and disseminating systematic reviews ... fallacy when considering possible patient-level confounding in a meta -analysis is to examine data from individuals Available online http://ccforum.com/content/12/4/220 Baseline risk: an example ... different studies are being combined to estimate one true effect of the intervention In contrast, the random-effects model does not assume an intervention has the same effect in each of the studies...

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False Discoveries in Mutual Fund Performance: Measuring Luck in Estimated Alphas pdf

Ngày tải lên : 30/03/2014, 06:20

... constrained to invest in high-expense funds (Elton, Gruber, and Blake (2007)) The remainder of the paper is as follows The next section explains our approach to separating luck from skill in measuring ... Evidence from a Bootstrap Analysis, Journal of Finance 61, 2551-2595 [25] Kostovetsky, Leonard, 2007, Brain Drain: Are Mutual Funds Losing their Best Minds? Working Paper, Princeton University [26] ... illustrate the beneﬁts of investing in actively-managed funds from a Bayesian perspective While these papers are useful in uncovering whether, on the margin, outperforming mutual funds exist, they...

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Báo cáo sinh học: " Likelihood and Bayesian analyses reveal major genes affecting body composition, carcass, meat quality and the number of false teats in a Chinese European pig line" ppsx

Ngày tải lên : 14/08/2014, 13:22

... Mendelian samples obtained, every 10 to 36th was retained for inference while the lowest burn -in period and thinning interval retained were equal to 1111 and 691, respectively Chain length ranged ... remained valid Gibbs sampler A trial Gibbs chain of 10 000 iterations was run for each trait and evaluated using the Gibbsit programme [21] to determine the burn -in period (b) and the thinning interval ... Bayesian-GS results: Gibbs chain characteristics (means of the three chains per trait) Burn Spacing Chain in between length iterations retained Pnmt (2) initial-ﬁnal % of Spacing MCse (3) Mendelian...

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Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas

Ngày tải lên : 05/09/2013, 10:17

... cooperating institutions during sampling Table - Sampling conditions and cooperating institutions during sampling Site Z japonica Code Sampling Month-Year Water Water depth temp (m) (℃) n Cooperating ... freeze-drying The granulated samples were stored in a freezer (-20ºC) Analysis of carbon stable isotope The granulated samples were used for analysis Carbon stable isotope ratio was determined using ... and LCFAs were contained in greater amounts in the roots and rhizomes than in the leaves and stems, and 18:3n3 was contained in lesser amounts in the roots and rhizomes than in the leaves and stems...

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Tài liệu Báo cáo khoa học: "Use of Mutual Information Based Character Clusters in Dictionary-less Morphological Analysis of Japanese" ppt

Ngày tải lên : 20/02/2014, 18:20

... set of training data using or not using character clustering 15 Table shows results obtained from training sets of ATR-travel The upper figures in each box indicate the results when using the character ... research include investigating the correlation between accuracy and the training data size, the number of questions as well as exploring methods for factoring information from a "dictionary" into ... a certain node in the structure Having a way of organizing classes of characters is clearly an advantage in describing facts in Japanese The next section presents such a method Mutual Information-Based...

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Báo cáo khoa học: In situ proton NMR analysis of a-alkynoate biotransformations ppt

Ngày tải lên : 08/03/2014, 08:20

... both investigated aerobic biotransformations, indicating that the presence of one or two carboxyl groups does not considerably in uence the substrate acceptance To determine the metabolic Strain ... obviously induced other enzymes that metabolise this substrate in a different way Performing the propynoate biotransformation in 1H2O/ D2O (1 : 1) led to an incorporation of 50% deuterium in all ... P putida strain was about 10 times faster than the spontaneous decarboxylation, indicating the presence of an induced decarboxylase in the organism The accumulated pyruvate was mainly hydrolysed...

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Báo cáo khoa học: Nigrocin-2 peptides from Chinese Odorrana frogs – integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis pot

Ngày tải lên : 15/03/2014, 10:20

... described as brevinin 1HS, esculentin 1S, esculentin 2S, odorranin C7HSa and odorranin PB Antimicrobial activity of nigrocin-related peptides The minimum inhibitory concentrations obtained for each ... domain between Cys15 and Cys21 is underlined Peptide Original fraction Mass observed (Da) Mass calculated (Da) Amino acid sequence Nigrocin-2LVa Nigrocin-2LVb Nigrocin-2SCa Nigrocin-2SCb Nigrocin-2SCc ... feature of nigrocin-2 peptides is reminiscent of the glycine ⁄ leucine-rich dermaseptin orthologues from the skins of neotropical phyllomedusine leaf frogs, named plasticins [30] Nigrocin-2 peptides...

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how to use excel in analytical chemistry and in general scientific data analysis pptx

Ngày tải lên : 17/03/2014, 02:20

... ACOSH(1.5) ϭ0.962424 The inverse sine, arcsin, in radians: ASIN(0.5) ϭ0.523599 The inverse hyperbolic sine, arsinh, in radians: ASINH(0.5) ϭ0.481212 The inverse tangent, arctan, in radians: ATAN(0.5) ... ASIN(x) ASINH(x) ATAN(x) ATAN2(x,y) ATANH(x) COS(x) COSH(x) SIN(x) SINH(x) TAN(x) TANH(x) The inverse cosine, arccos, in radians: ACOS(0.5) ϭ1.047198 The inverse hyperbolic cosine, arcosh, in ... Preface however, is on numerical analysis, and it covers such aspects as finding roots and fitting curves, integrating, differentiating, smoothing, and interpolating data Numerical solution of differential...

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Báo cáo Y học: Role of histidine 42 in ascorbate peroxidase Kinetic analysis of the H42A and H42E variants pptx

Ngày tải lên : 18/03/2014, 01:20

... derivative of CcP [52], no such interaction was detected in the crystal structure of Compound I [53,54] Instead, stabilizing hydrogen-bonding interactions from the distal arginine residue have been identiﬁed ... hydrogenbonding interactions involving Arg38 in rAPX have been simultaneously disrupted as a secondary consequence of the His42 mutations and, together with His42, may be in uential in deﬁning the ... performed by global analysis and numerical integration methods using PROKIN software (Applied Photophysics) RESULTS Mass spectrometry The integrity of the variant proteins was examined to ensure that...

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The Harvard Research in International Law: Contemporary Analysis and Appraisal pot

Ngày tải lên : 23/03/2014, 10:21

... a special interest in the history of international law His publications include the Intertwining of Law and Theology in the Writings of Hugo Grotius in the Journal of the History of International ... Harvard Research in essaying a universal 280 281 282 283 284 285 Chapter Chapter Chapter Chapter Chapter Chapter 4, infra 5, infra 6, infra 7, infra 8, infra 9, infra HeinOnline John P Grant ... reprinted by W.S Hein in the HarvardResearch in InternationalLaw (2008) The text of the draft convention appears below as Appendix HeinOnline John P Grant & J Craig Barker, Harv Research in International...

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Báo cáo " North Atlantic Treaty - a global document in a Critical Discourse Analysis " docx

Ngày tải lên : 28/03/2014, 11:20

... friendly international relations by strengthening their free institutions, by bringing about a better understanding of the principles upon which these institutions are founded, and by promoting conditions ... United Kingdom due to the alphabetical order, has always been playing a very important role for its own interest in running different organizations, including NATO, when participating in them ... and he has an interest in “uncovering inequality, power relationships, injustices, discrimination, bias, etc” Fairclough [1] has had the ideas in common with most of the above interpretations...

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Does Central Bank Financial Strength Matter for Inﬂ ation? An Empirical Analysis docx

Ngày tải lên : 29/03/2014, 07:20

... indeed taken its financial results into account in the preceding decade, claiming that this had become an undesirable policy constraint in practice, interfering with monetary policy and leading ... for inflation inertia 4.1 Structural Determinants of Inflation (Control Variables) In this subsection we present the choice of structural inflation determinants – based on other studies findings ... for introducing an inflation targeting framework, this effect being statistically significant, rather strong (around three percentage points) and stable Our analysis thus confirms previous findings...

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Báo cáo khoa học: Ca2+-binding allergens from olive pollen exhibit biochemical and immunological activity when expressed in stable transgenic Arabidopsis pdf

Ngày tải lên : 30/03/2014, 10:20

... Ca2+binding proteins (CaBPs) Both proteins possess in their sequences the structural EF-hand motif, composed of 12 conserved amino acid residues directly implicated in the binding of the protein ... This fragment includes the 5¢- and 3¢-noncoding region as well as the nucleotides that encode the protein consisting of 84 amino acid residues including the N-terminal methionine In the case of ... also included in the analysis Recombinant proteins were able to bind IgE from all the olive-allergic sera but not from the negative control (Fig 6A) The binding capacity of the isolated proteins...

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PROFIT-SHARING CONTRACTS IN HOLLYWOOD: EVOLUTION AND ANALYSIS ppt

Ngày tải lên : 30/03/2014, 12:21

... II period, increasing to 74 in 1960 from 32 in 1946.51 As we shall see,52 this coincides with an increase in the use of sharing contracts.53 47 Average tenure in ofﬁce for executives in charge ... signiﬁcant decline in attendance and (real) revenues in the 1950s I return to this point, and its possible role in the kinds of contracts movie studios write, in Section IVA1 III Contracting in Hollywood ... of an industry study tabulating the size and in uence of various facets of the entertainment industry (for example, Harold Vogel, Entertainment Industry Economics PROFIT-SHARING CONTRACTS IN HOLLYWOOD...

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current methods in forensic gunshot residue analysis

Ngày tải lên : 03/06/2014, 01:51

... melting point 850°C/1562°F Deoxidizing alloys of tin, copper (Cu), Pb, and zinc (Zn), radiography, in heat-treating baths for tempering of steel, in laser crystals, dyes, inks, leather tanning, ... in this study would be difﬁcult to examine in the standard SEM without coating Fabric, for instance, requires extensive rotating and tilting during the coating procedures The following case studies ... generates fewer interfering peaks, but the problem of differentiating coating vs specimen C remains A more recent approach to the elimination of charging effects is to maintain some atmosphere in the...

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báo cáo sinh học:" Monitoring the newly qualified nurses in Sweden: the Longitudinal Analysis of Nursing Education (LANE) study" ppt

Ngày tải lên : 18/06/2014, 17:20

... [38], in this case pursuing nursing education and entering the nursing labour force The design chosen was advantageous here because many different risk factors were of interest during studies, in ... towards nursing education [58] and are more inclined to leave the profession [79,80] As a result, men can be assumed to be less interested in participating in a study directly addressing nursing issues ... attending the last semester of the nursing programme in the autumn of 2006 could be defined in advance and included in the sampling frame This limitation will be controlled for when contrasting...

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báo cáo hóa học: " Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies" doc

Ngày tải lên : 20/06/2014, 00:20

... urine values were creatinine-corrected for each sample (the isocyanate concentrations were expressed in μg per g of creatinine) Urinary creatinine was determined in grams per liter (g/L) using ... monitoring air contamination Heavy work increases physical demands and ventilation, exacerbating the degree of incorporation Absorption through the skin, ingestion and individual differences in metabolism ... isocyanates, these kinetics must be considered in planning biological monitoring in which urinary elimination is used as an estimate of uptake Two different sampling time points might be appriopriate...

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báo cáo hóa học:" Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: An analysis of 215 cases from the Malmö Diet and Cancer Study" potx

Ngày tải lên : 20/06/2014, 04:20

... shown in Figure 1A-D and the staining distribution in primary tumours vs metastases in Figure 1E-F Interestingly, and in line with previous in vitro data [20], RBM3 expression was strong in the ... its clinical utility in stratification of melanoma patients should be validated in future studies According to current clinical guidelines in Sweden, sentinel node biopsy is performed in melanomas ... [15] As RBM3, when present, was expressed in > 75% of the cells, predominantly in the nuclei and in varying intensities, only the intensity of the staining was accounted for and denoted a score...

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báo cáo hóa học:" Effects of low power laser irradiation on bone healing in animals: a meta-analysis" pptx

Ngày tải lên : 20/06/2014, 04:20

... strength in such studies The purpose of this study was to conduct a systematic review and meta -analysis of animal studies that investigated low-level laser irradiation effects on bone healing Our inclusion ... required that studies have a quantitative biomechanical measures of bone strength since this is considered the most reliable and definitive indicator of bone healing in animal studies [25,26] ... papers using the structured critical appraisal tool designed for studies evaluating interventions in animal models independently (QATRS) We arbitrarily classified the quality of the animal studies...

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