estimated costs of dismantling removing or restoring items of property plant and equipment included as an increase in the value of the assets specifying the circumstances considered in the measurement process

Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt

Ngày tải lên : 18/02/2014, 18:20

... versus the corresponding control the sciatic nerve at several time points after LPS injection and found that their levels had increased by h and were especially high at h This increase lasted for ... cytokines and chemokines, to express major histocompatibility complex (MHC) class II molecules and adhesion molecules, and to serve as antigen-presenting cells [18–20] These chemokines and in ammatory ... mediates the rapid induction of cytokines and adhesion molecules that are implicated in immune and in ammatory responses [24,25] Mitogen-activated protein kinases (MAPKs) are important mediators of...

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Báo cáo Y học: Amphipathic property of free thiol group contributes to an increase in the catalytic efﬁciency of carboxypeptidase Y pot

Ngày tải lên : 08/03/2014, 23:20

... (Cys341) is involved in substrate binding at the S1 subsite and in maintaining the width and depth of the S1 subsite; (b) the rearrangement of the S1 subsite induced by the interaction between the SH ... support for a scenario in which the hydrophobicity of the SH group of Cys341 is important for substrate binding and maintaining the solvent-accessible cavity at the S1 subsite However, in the case ... JM109 was transformed by the method of Hanahan [16] using a standard transformation buffer Puriﬁcation of wild-type and mutant forms of carboxypeptidase Y Typical puriﬁcations were carried out as...

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Báo cáo y học: "Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT" pdf

Ngày tải lên : 12/08/2014, 11:22

... responsibility for the integrity of the data and the accuracy of the data analysis AZ, JL and AS determined the study concept and design AS, GRB, BK-L and WD acquired the data AS, JL and AZ analysed and interpreted ... period in all patients without prior malignancy We included all types of cancer except for basal cell carcinomas One M Bowen was reported and included There was no report of other carcinomas in situ ... Recurrence of a prior malignancy During follow-up 15 recurrent cancers were observed in 14 patients including 14 recurrences of the same type and site as the prior tumor and one metastasis of unknown origin...

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Tài liệu Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area ppt

Ngày tải lên : 18/02/2014, 11:20

... tested Owing to the interaction between bis-ANS and ATP, the binding assay provided only reliable performance in a short range of the bis-ANS concentrations tested in Fig 2, and only lm, 1.5 lm and ... by an interaction between the apolar acyl chains of the phospholipids and side chains of particular amino acids, thus accounting for the increased capacity to penetrate to the interior of the ... including ATP Fluorescence measurements including HSL and SYPRO Orange For the evaluation of the increase in hydrophobicity of HSL after phosphorylation by PKA, the commercial probe SYPRO Orange (from...

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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Ngày tải lên : 07/03/2014, 21:20

... ligand Furthermore, normal antagonist binding established that substitution of the arginine had not resulted in a distorted or misfolded receptor protein In contrast to the three classes of antagonist, ... cells and characterized pharmacologically In each case the binding aﬃnity (pKi) of AVP and the pEC50 value for AVP-induced accumulation of mono-, bis- and tris-phosphates (InsP– InsP3) was determined ... domain is critical for high afﬁnity agonist binding but not antagonist binding [14] The corresponding residue in the OTR is also an arginyl (Arg34) and furthermore this arginyl is required for...

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Báo cáo khoa học: Mitochondrial transcription factor A overexpression and base excision repair deﬁciency in the inner ear of rats with D-galactose-induced aging pdf

Ngày tải lên : 14/03/2014, 23:20

... to the membrane in the precursor form, and could not be translocated to and processed in the mitochondrial matrix An age-dependent decline in the mitochondrial import of BER proteins into the ... degeneration of the central auditory system, the age-related changes of the peripheral auditory system also play an important role in the development of presbycusis However, as the organ of Corti (part of ... relative abundance of the protein tested As compared with the control group, the expression of TFAM protein in the inner ear of the low-dose, medium-dose and high-dose d-Gal groups was increased by...

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Báo cáo khoa học: MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma pdf

Ngày tải lên : 14/03/2014, 23:20

... fraction of cells in G1-phase was significantly increased in the miR-373 ASO group, and the fraction of cells in S-phase was significantly decreased in the miR-373 ASO group (B) In the pri-373 group, the ... examined the effects of PPP6C knockdown on the cell cycle (Fig 6E) Knockdown of PPP6C resulted in a significant decrease in the proportion of cells in G1-phase and an increase in the proportion of ... (Ambion), using BamHI and HindIII sites To construct the PPP6C expression plasmid, the coding sequence (ORF) without the 3¢-UTR of human PPP6C was amplified by RT-PCR and inserted into the EcoRI and XhoI...

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ENVIRONMENTAL INDICATORS: A SYSTEMATIC APPROACH TO MEASURING AND REPORTING ON ENVIRONMENTAL POLICY PERFORMANCE IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT pot

Ngày tải lên : 15/03/2014, 16:20

... not easily measured and can only be estimated on the basis of such indirect measures as human population distribution or the presence of roads and other infrastructure Others can be measured, and ... natural gas for all years and includes estimates of the value of the net change in forest, and of the degradation of land, water, and unspecified "other" resources only for 1990 (25) The depreciation ... manufacturing (including mining) Pollutants, waste, and materials dissipation stem mainly from manufacturing (including mining), energy production and consumption, agriculture, the transport sector, and...

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LOW INTEREST RATES AND HIGH ASSET PRICES: AN INTERPRETATION IN TERMS OF CHANGING POPULAR MODELS doc

Ngày tải lên : 17/03/2014, 08:20

... understanding of the economy, including common understandings of liquidity, the significance of inflation, and real interest rates, and how their thinking has impacted both asset prices and interest ... rates for the discounting of future corporate cash flows or to the correction that must be made to corporate earnings for the real value of the interest owed by the corporation: the financial ... confining short-term fluctuations in the federal funds rate.10 These words clearly ring, in sound if not fully in substance, as an acceptance of the Friedman formula, and willingness to accept the...

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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt

Ngày tải lên : 20/03/2014, 03:20

... ung th in vitro, thấy quercetin làm thoái giáng đột biến p53 - protein, làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức ... (+) Gluco corticoid Lipomodulin (-) phospholipase phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien ... gemcitabin topotecan Bromelain Là hỗn hợp protease chứa S, lấy từ thân dứa (Ananas conosus L.Merr, họ Bromeliaceae) Từ 1957, hàng trăm 98 nghiên cứu công bố áp dụng điều trị bromelain, nh kìm hãm...

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Fertility of Men and Women Aged 15–44 Years in the United States: National Survey of Family Growth, 2006–2010 docx

Ngày tải lên : 22/03/2014, 11:20

... mother and parental living arrangements at age 14 The definition of Hispanic origin and race used in this report takes into account the reporting of more than one race, in accordance with the ... because mothers report information for the birth registration system Not all mothers report information about the fathers of their babies, and if they do, their reports of the father’s age and other ... • The Office of the Assistant Secretary for Planning and Evaluation NCHS gratefully acknowledges the contributions of these programs and agencies, and all others who assisted in designing and...

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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf

Ngày tải lên : 22/03/2014, 21:20

... blotting Recombinant CDHis was subjected to SDS-PAGE and immunoblotting The membrane in lane was incubated with D123 and the protein was detected using anti-D123 serum Other membranes containing electroblotted ... are in agreement with the pull-down and far western assays, showing a lack of interaction for the individual SBDs and also in the absence of the D(316–344) and D(495–535) regions of the D2 and ... by other aromatic residues (tyrosine in D1 and D2 and phenylalanine in D3), whereas W563 is conserved only in D2, but not in the D1 or D3 domains Moreover, on the basis of bioinformatics analysis,...

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**Film, Politics, and Ideology: Reflections on Hollywood Film in the Age of Reagan* ppt**

Ngày tải lên : 23/03/2014, 12:20

... of good and evil involved in almost all historical undertakings On the other hand, Rambo and the other Stallone-Norris meathead films can be read as symptoms of the victimization of the working ... myth, and the cinematic apparatus as well as in ideas or theoretical positions Another limitation with the classical M arxian theory of ideology, sometimes referred to as the Dominant Ideology thesis ... militarism, and communism that serve as soft and hard core propaganda for Reaganism and a distinctly rightwing interventionist and militarist agenda On the other hand, M issing, Under Fire, Salvador,...

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Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc

Ngày tải lên : 30/03/2014, 08:20

... leading to an increased DWm 3004 [17,20] The CsA analog N-methyl-4-isoleucine-cyclosporin (NIM811) is also known as an inhibitor of MPTP, and to lead to an increase in DWm [21] Fluorescent probes ... as a useful control substance in this context, because it is an inhibitor of P-glycoprotein rather than MPTP, and is devoid of calcineurin-inhibiting properties [23] We hypothesized that an increase ... cells and GLC4 ⁄ P-glycoprotein cells to investigate the effects of CsA and its analogs on DWm There were no signiﬁcant increases in JC-1 ﬂuorescence in response to either CsA or its analogs in...

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Báo cáo khoa học: The inhibition of Ras farnesylation leads to an increase in p27Kip1 and G1 cell cycle arrest pdf

Ngày tải lên : 31/03/2014, 01:20

... number of Rat1/ras cells in the S phase The time course of HR12-induced inhibition of Ras processing correlates with the decrease in pRb phosphorylation Fig Inhibition of anchorage independent and ... processing and the accumulation of p27Kip1 ([6] and Fig 5) We observed an increase in p27Kip1 levels in the cyclin E/Cdk2 complex, and a corresponding reduction in the kinase activity of the complex ... both as a substrate and as an inhibitor of Cdk2 In summary, HR12 inhibits the degradation of the p27Kip1 protein in Rat1/ras cells, possibly via the Ras-to-RhoA pathway Is the increase in p27Kip1...

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Báo cáo Y học: Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway pot

Ngày tải lên : 31/03/2014, 21:21

... effect of Topo I inhibitors used as cancer therapeutic agents The identification of manganese as a cofactor increased the sensitivity of this enzymatic assay, and the 96well format developed for this ... varying pH Increases in absorbance at 415 nm were monitored and the amount of released products was calculated based on the extinction coefficient (e) of 15 000 M)1Æcm)1 The rate was then determined ... variant with lane and 2: uninduced (–) and induced (+) culture, lane and 4: soluble (S) and insoluble (I) fraction of the crude lysate, lane 5, 6, 7, and 8: load, flow-through, wash and eluted fractions...

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believing by faith an essay in the epistemology and ethics of religious belief may 2007

Ngày tải lên : 11/06/2014, 05:31

... guidance is left behind (if, indeed, it can ² The perspective of Reformed epistemology is set out in essays by William Alston, Alvin Plantinga, and Nicholas Wolterstorff in Alvin Plantinga and ... whether he could be justiﬁed in continuing to hold and act on his faith-beliefs in the absence of proof of their truth ⁴ The term ‘metaquestion’ is Plantinga’s: see Plantinga, Warranted Christian ... considering all the available evidence for and against the existence of the Christian God and comes to the conclusion that the balance of probability supports such belief and so feels vindicated in...

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Báo cáo sinh học: "Concomitant detection of IFNa signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNa-treated subjects at early times after repeated local cytokine treatments" doc

Ngày tải lên : 18/06/2014, 19:20

... evaluate and compare the modulations of PBMC global gene expression profiles induced by IFNa in melanoma and normal donors The effects of the administration of different doses of IFNa, as well as of ... FlowJo software (Tree-Star), excluding dead cells and including cells falling in the expected morphological gate The band pass filter used for cytofluorimetric analysis was 525 nanometers for FITC, ... at the protein level the effect of this cytokine on chemoattraction and inflammation observed at the transcription level in vitro and in vivo, corroborating the results of the gene ontology analysis...

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báo cáo hóa học: " Joint optimization of MIMO radar waveform and biased estimator with prior information in the presence of clutter" pot

Ngày tải lên : 21/06/2014, 02:20

... see that the CRB obtained by our method or uncorrelated waveforms decreases as the increasing of ASNR, while increases as the decreasing of CNR Moreover, the CRB under the Trace-opt or Eigenopt ... (17) The problem of main interest in this study is the joint optimization of the WCM and bias estimator to improve the performance of parameter estimation by minimizing the constrained biased ... receiver (in units of wavelengths), respectively Let the weighted matrix M = I and g = in the case of the weighted norm constraint, and T = I and g = 0.5 in the other case In the following examples,...

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