... maintaining the integrity ofthe endothelium through both direct and indirect mechanisms APC can potentially limit the elaboration of proinflammatory cytokines, such as tumor necrosis factor-α ... No Looney and Matthay Figure Proposed schema for APC signaling inthe endothelial cell APC binds to EPCR, which then interacts with the S1P1 receptor leading toits phosphorylation by PI3-kinase ... permeability to protein (unpublished data) The reason for the conflicting results of endothelial barrier protection inthein vivo studies is not clear, but these findings reinforce the need to cautiously...
... experienced during the peacekeeping deployments ofthe 1990s andin other contingency deployments of earlier decades Helmus and Glenn (2005) note that according to their interviews of infantry troops ... conducted within the RAND National Security Research Division (NSRD) ofthe RAND Corporation NSRD conducts research and analysis for the Office ofthe Secretary of Defense, the Joint Staff, the Unified ... conducts research and analysis for the Office ofthe Secretary of Defense, the Joint Staff, the Unified Commands, the defense agencies, the Department ofthe Navy, the U.S Intelligence Community,...
... the differences inthe behaviors and attitudes ofthe grandmother, the father andthe mother andthe children at least cause discontent toone another The grandmother held the floor most ofthe ... plot, theme, point of view, character and setting Technique has to with the structuring ofthe story into the plot so that the writer can convey the theme andthe manipulating ofthe language in ... from the beginning ofthe story in her decision where to go, in her introduction ofthe scenery along the journey While the father, the mother andthe children enjoyed going to Florida, The grandmother...
... weekends inthe spring of 1996 During the ®rst weekend, subjects responded to questions on food stimuli, and during the second they ®lled inthefood neophobia scale In addition to information ... than those living inthe countryside, andthe eect of living area may, again, be of a similar origin Some items on the FNS scale, referring to contacts with ethnic foods and visits to ethnic restaurants, ... 3.1 Food neophobia scale The scale items loaded mainly on two factors (Table 1) The ®rst is related tothe interest (or disinterest) in trying new and ethnic foods The second appears to relate to...
... certain locations The first two places to look are at the beginning and at the end Many writers begin with a statement of purpose, containing what they are trying to prove Others summarize their ... advantage ofthe fact that children are often not able to discriminate between the cartoons andthe ads and not understand that these things offered come at a cost Often the advertising is about ... specific information that someone uses to furnish "proof for something she is trying to claim is true Communicators appeal to many kinds of evidence to "prove their point." These include "the facts,"...
... determine whether changesin temperature cause changesinthe structure ofthe insect AFPs andto further characterize the TXT face of these proteins, the backbone dynamics of TmAFP and sbwAFP were ... sbwAFP and TmAFP using only the Ca atoms ofthe threonines inthe TXT motif (Fig 8A) Given the different handedness, the proteins align with the termini orientations opposite toone another, yet the ... mutated to Leu (sbwAFP) or to Tyr (TmAFP) andthe TH activity ofthe protein was measured The top ofthe panel shows the protein with the TXT face oriented towards the viewer, while the bottom shows...
... Domain Database of NCBI was screened with the protein coding sequence of clone of CLAP andthe Fas I domains inthe protein compared with 10 other fasciclin I-containing proteins The most highly ... Processing ofthe pro-CLAP C-terminus is essential to lower the molecular mass and pI ofthe protein to values observed by SDS/ PAGE and IEF Interestingly, pool sequencing ofthe mixture of CNBr ... region ofthe fasciclin domains Because the fasciclin domains inthe Conserved Domain Database are compared with only oneofthe four domains present inthe Drosophila protein [37], its sequence...
... understand and maintain their roles, including helping the council members understand their responsibilities Finally, inthe policy initiator role, the mayor develops programs and policies to address ... administrator It is important for lower and midlevel administrators to understand what goes on at t he top ofthe organization inthe interactions between the top elected officials andthe top ... form in cities has steadily increased since its appearance inthe fi rst decades ofthe twentieth century, andthe trend continues Since 1990, the number of cities over 2,500 in population using the...
... Cooperazione e Sviluppo (2004) Cooperazione Internazionale (2004) Coordinating Board of Jewish Organizations (1947) Coordinating Body ofthe Indigenous Organizations inthe Amazon Basin (2003) Coordinating ... (2003) Institute of Cultural Affairs International (1985) Institute of Global Education (1998) Institute of Inter-Balkan Relations (1998) Institute of Internal Auditors (1989) Institute of International ... (2000) Institute of International Sociology of Gorizia (2006) Institute of Marine Engineering, Science and Technology (2008) Institute of Social Studies Trust (1996) Institute on Human Rights and the...
... diversification into non-hydrocarbon industries; and food, water and power securityinthe GCC Key findings ofthe first phase of our research on the GCC andthe global economy include the following: l The ... their assets more widely, making investments in Asia, Africa and within the Gulf region itself Industrialising economies in Asia are intensifying their trade links with the Gulf and some ofthe ... despite a testing period in recent years, the US is likely to maintain a significant presence inthe Gulf, both to protect shipping andto guarantee thesecurityofits allies inthe region European...
... Two ofthe most influential factors for the delay are the difficulties in identifying the level of sustainable management andthe amount of contribution tothe Fund 20 It is not hard to imagine ... so-called “prisoners dilemma” under game theories New findings out ofthe thesis This thesis presents the following new findings (1) New findings related to theory (a) A new economic equation to relate ... forests The purpose ofthe thesis is to examine how International Agreements envisage to contributing to conservation ofthe global environmental assets that are diminishing rapidly at an increasing...
... with an indiscriminate and often insensitive dismissal of what often amounts to peoples world views, ways of imagining, dreaming, and organizing their individual and social lives The process of unmasking ... linearity as oneofits main and most powerful tropes, then any attempt to understand the notoriously elusive nature ofthe nation should involve the unsettling of that linearity OUTLINE OFTHE BOOK ... people in Greece dealt with the weight of classical tradition; they have also pointed tothe paradox ofthe centrality ofthe classical past inthe western imagination on theone hand, andthe relative...
... "2B" bINSS stage was not separated into stages and 4S since 4S is for infants INSS (International Neuroblastoma Staging System) according to Simpson and Gaze [27] at autopsy Using this orthotopic ... To detect NB cells inthe bone marrow ofthe iliac crest, CgA-stained sections were examined in a blinded fashion by independent investigators Two to CgApositive cells inone section were classified ... vehicle compared to metastatic incidence of NB at INSS stages and 4S in clinic [28] Data shows microscopic metastases inthe marrow ofthe iliac crest, and composite data of macro- and microscopic...
... diagnostics in recent years In contrast tothe genome, the proteome is dynamic andits fluctuations depend on a combination of numerous internal and external factors Identifying and understanding changes ... areas ofthe raw spectra, averaging of technical repeats, binning of neighboring points to reduce data complexity, removal ofthe spectral area below baseline and normalization ofthe total ion ... different time points of therapy (i.e., before the start of therapy, after the surgical removal ofthe tumors, andone year after the end of basic therapy) that allowed obtaining individual differential...
... functioned in cytoplasmic envelopment of capsids [27] Importantly, syncytial mutations in either gB or gK failed to cause fusion inthe absence ofthe UL20 gene, indicating that the UL20 protein ... envelopment and virusinduced cell fusion [30] In this manuscript, we show that the amino and carboxyl termini of UL20p contain distinct domains that function in infectious virion production and intracellular ... fusion to occur As is the case with the carboxyl terminus of UL20p discussed earlier, these results suggest that the amino terminus of UL20p contains functionally separable domains involved in cytoplasmic...
... district, the yield module were 2.55 tons/ha in winter and 2.67 tons/ha in spring, the lowest yield in Phu Luong district in module (2.32 tons/ha in winter and 2.54 tons/ha in spring) The yield of module ... planted in spring crop was 35 plants/m2 and 45 plants/m2 in winter At these densities, the EY was 2.78 tons/ha in spring crop and 2.47 tons/ha in winter; the AY was 2.50 tons/ha in spring and 1.90 tons/ha ... tons/ha) The planting densities affected on the growing and developing indicators ofthe soybean varieties 99084 - A28 in spring and winter crops in Thai Nguyen The high densities caused an increase...
... performed inthe laboratory in 1999 The harvesting of seedlings and older trees to estimate growth to breast height was not allowed inthe core zone ofthe natural reserve, the ages of seedlings within ... understanding ofthe stand history ofthe Meyer spruce forest inthe typical steppe The aims ofthe current study are (i) to make a preliminary assessment ofthe possible development of a large-scale ... Chinese pine stands and low-average growth inthe Korean spruce stand indicated the incidence of large and deep depressions inthe 1920s andthe early 1930s For trees growing in semiarid regions, the...
... immunofluorescence and 3,3-diaminobenzidine disclosure) for aggrecan andthe staining intensity increased with time post injection (Figures and 5b) Aggrecan matrix staining within the vicinity ofthe injected ... tissue Inthe present article we established an in vitro model system to investigate the survival and phenotype of human MSCs following injection into bovine NP tissue explants to test the following ... following injection, andthe intensity ofthe matrix staining increased with time in culture (Figures and 5b) Weak staining for type II collagen was observed within a small number of cells in monolayer...
... the manuscript and aided inthe analysis DV participated inthe coordination CG and TK conceived ofthe study, and participated inits design and coordination All authors have approved the final ... related to a reference point inthe target volume as described in ICRU reports 50, 62 and 83 Determination ofthe parotid gland doses The planning target volumes and both parotid glands, the mandible, ... mandible, andthe larynx were outlined on the transversal slices ofthe planning CT-scans The planning goal was – while maintaining a homogeneous dose distribution inthe target volumes – to minimize...