cancer stem cells proteomic approaches for new potential diagnostic and prognostic biomarkers
Báo cáo y học: "Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study" pptx
Ngày tải lên :
10/08/2014, 09:22
... neuroendocrine cancers It follows that new biomarkers should be developed for definite diagnosis of those cancers, even if histopathology has long been the golden standard for diagnosis and determination ... triplicates were pooled and used for G-statistic calculation using a two-way contingency table arranged in two rows for a target protein and any other proteins, and two columns for cancer groups on ... 10-4, and 0.021, respectively) from LCNEC vs SCLC comparisons and thus specific to LCNEC Interestingly, AK1C1, AK1C3, AL1A1, and CD44 have been reported to be biomarkers of cancer stem cells...
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Báo cáo khoa học: "Collapsed Consonant and Vowel Models: New Approaches for English-Persian Transliteration and Back-Transliteration" ppt
Ngày tải lên :
23/03/2014, 18:20
... a new algorithm for English to Persian transliteration, and a novel alignment algorithm applicable for transliteration Our new transliteration method ( CV- MODEL 3) outperforms the previous approaches ... GIZA ++ and the new alignment for English to Persian transliteration Transliteration accuracy increases in TOP -1 for both corpora (a relative increase of 7.1% (p=0.002) for the Small corpus and ... retrieval In Conference on Information and Knowledge Management, pages 139–146 Slaven Bilac and Hozumi Tanaka 2005 Direct combination of spelling and pronunciation information for robust backtransliteration...
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báo cáo hóa học:" Ovarian cancer: emerging concept on cancer stem cells" docx
Ngày tải lên :
20/06/2014, 07:20
... cancer stem cells Self-renewal and differentiation potentials are the features of stem cells Origin of cancer stem cells Self-renewal and differentiation potentials are the features of stem cells ... stem cells developed up to therapy for the cancer and other disorders for the blood [11] and following HSC study for other stem cells will lead to improve therapy for other cancers Cancer stem cells ... self-renewal in normal stem cells and cancer stem cells, there are mechanistic differences in some cancers Interestingly, the mechanistic differences in selfrenewal between normal stem cells and cancer...
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Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps
Ngày tải lên :
10/08/2014, 05:21
... prostate formation by the transformed P63+ basal /stem cells in the metastatic loci The data evidently demonstrated both cancer cell and stem cell characteristics of the transformed P63+ basal /stem cells, ... overexpression P63+ basal /stem cells were transformed into AR+ or ARcancer cells but rarely into ChgA+ neuroendocrine cancer cells Conventional human prostate cancer cells include malignant cells of luminal, ... Basal /stem cells are the origin of all prostate intraglandular cells [1,27] and P63 has been proposed to be required for prostate stem cell plasticity and differentiation [27,28] Thus, PCSCs are potentially...
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báo cáo khoa học: " MicroRNAs involved in neoplastic transformation of liver cancer stem cells" pot
Ngày tải lên :
10/08/2014, 10:20
... tissue and tumors With the accumulation of evidence for cancer stem cells , it is proposed that miRNAs might play a role in malignant transformation from normal stem cells into cancer stem cells ... differentiation of normal stem cells strongly suggest that miRNA may be involved in the transformation of normal stem cells into cancer stem cells Therefore, screening for differences in miRNA ... ability of stem cells to self-renew, and their ability to differentiate for the purpose of development and tissue maintenance versus their potential for dysregulated growth and tumor formation...
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báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc
Ngày tải lên :
10/08/2014, 10:20
... factor in cancer cells, even cancer stem cells Another example is miR21, which has been reported to have extensive roles and is expressed in embryonic stem cells [29], neuronal cells [30] and several ... hybridisations for MCF-7 cells & BCSCs a and b show microarrays for MCF-7 cells, and c and d show microarrays for BCSC cells Table S1-MiRNAs microarray- based miRNAs expression profile of MCF-7 cells ... used for bioinformatic analysis and target prediction for the miRNAs Real-time RT-PCR Results Isolation and culture of ESA+CD44+CD24-/low cells The expression of ESA, CD44 and CD24 in MCF-7 cells...
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báo cáo khoa học: " Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?" pot
Ngày tải lên :
11/08/2014, 20:20
... ectopic bone formation of embryonic stem cells and cord blood stem cells in vivo Tissue Eng Part A 2010, 16:2475-2483 Luo JZ, Xiong F, Al-Homsi AS, Roy T, Luo LG: Human BM stem cells initiate ... embryonic stem cells Head Face Med 2008, 4:10 doi:10.1186/1746-160X-7-5 Cite this article as: Handschel and Meyer: Infection, vascularization, remodelling - are stem cells the answers for bone ... Cell-based immunotherapy with mesenchymal stem cells cures bisphosphonate-related osteonecrosis of the jaw-like disease in mice J Bone Miner Res 2010, 25:1668-1679 Handschel J, Naujoks C, Langenbach...
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cancer stem cells theories and practice_part1 pps
Ngày tải lên :
12/08/2014, 06:20
... Stem Cells to Overcome Drug Resistance 401 Miaorong She and Xilin Chen Chapter 21 Cancer Stem Cells and Chemoresistance Suebwong Chuthapisith Chapter 22 Cancer Stem Cells in Drug Resistance and ... Chapter Prostate and Colon Cancer Stem Cells as a Target for Anti -Cancer Drug Development Galina Botchkina and Iwao Ojima Niches and Vascularization 135 155 Importance of Stromal Stem Cells in Prostate ... Culture, Markers and Targets for New Combination Therapies Candace A Gilbert and Alonzo H Ross Chapter 79 Cancer Stem Cells in Lung Cancer: Distinct Differences between Small Cell and Non-Small...
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cancer stem cells theories and practice_part2 pdf
Ngày tải lên :
12/08/2014, 06:20
... driving force for transforming normal stem cells to cancer stem cells Adult normal stem cells represent one purported origin of cancer stem cells What causes the transformation from normal stem cells ... checkpoint activation and apoptosis in cancer stem cells Another possible reason for increased genomic instability in cancer stem cells is malignant transformation of aged stem cells Stem cells have a ... instability and cancer stem cells appear to be intimately connected Genomic instability might be a potential driving force in the transformation of normal stem cells into cancer stem cells Future...
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cancer stem cells theories and practice_part3 pot
Ngày tải lên :
12/08/2014, 06:20
... marker for both normal neural stem cells and glioma stem cells, and may identify new CD133- glioma stem cells 4.4 New markers: Podoplanin and Integrin Alpha There are two new promising cancer stem ... www.adultpdf.com 80 Cancer Stem Cells Theories and Practice Discovery of neural and glioma stem cells The discovery of adult neural stem cells paved the way for the glioma stem cell field Until ... modulate stem cell proliferation [62] Murine and human hematopoietic stem cells [63-64], murine neural stem cells [65], normal and malignant human mammary stem cells [66], and normal and malignant...
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cancer stem cells theories and practice_part4 ppsx
Ngày tải lên :
12/08/2014, 06:20
... suggestion that prostate and colon cancers cells with high combined expression of CD133 and CD44 represent stem- like cells with high tumorigenic and sphere-forming potentials, and significantly up-regulated ... 126 Cancer Stem Cells Theories and Practice Table Cancer stem cell markers in small cell lung carcinoma amd non-small cell lung carcinoma This is trial version www.adultpdf.com Cancer Stem Cells ... tumor-driving cells - cancer stem cells (CSCs) Tumor cells with a stem cell-like properties, such as self-renewal and ability to differentiate into multiple cell types characteristic for particular...
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cancer stem cells theories and practice_part8 pptx
Ngày tải lên :
12/08/2014, 06:20
... tumorinitiating and undergo self-renewal Thus, a certain subpopulation of cancer cells is able to self-renew and initiate tumor formation, supporting the term cancer stem cells Self-renewal of cancer stem ... (Sharma et al.) Therefore, microRNAs’ role in stem cell regulation and cancer formation and progression are an attractive area of research Self-renewal of cancer stem cells Stem cells are defined ... (Papagiannakopoulos and Kosik, 2008) According to this cancer stem cell hypothesis, cancer stem cells are tumorinitiating cells that proliferate uniquely through self-renewal Cancer stem cells are thought...
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cancer stem cells theories and practice_part9 docx
Ngày tải lên :
12/08/2014, 06:20
... different settings and tumor types In this chapter we will review this issue with depth Stem cells and cancer stem cell theory Stem Cells In order to understand cancer stem cells a brief description ... J.A (2010) Metformin and cancer: Doses, mechanisms and the dandelion and hormetic phenomena Cell Cycle, in press This is trial version www.adultpdf.com 376 Cancer Stem Cells Theories and Practice ... high propensity to form tumours Therefore these cells are referred to as cancer stem cells (CSC) or cancer stem- like cells or, better, tumour-initiating cells (TICs) The terminology, while not...
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Báo cáo y học: "Population genetics of cancer cell clones: possible implications of cancer stem cells" pptx
Ngày tải lên :
13/08/2014, 16:20
... MF, Weisman IL: Stem cells, cancer and cancer stem cells Nature 2001, 414:105-111 15 Shipitsin M, Polyak K: The cancer stem cell hypothesis: in search of definitions, markers, and relevance Lab ... Vormoor J: Understanding the cancer stem cell Br J Cancer 2010, 103:439-445 11 Lindeman GJ, Visrader JE: Insights into the cell of origin in breast cancer and breast cancer stem cells Asia Pac J ... subset of the cancer cells (the stem cells) we can see that for any size of tumour, because of the much smaller number of stem cells, clonal evolution is predicted to be faster in stem cells compared...
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Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
Ngày tải lên :
14/08/2014, 08:21
... data analysis and design SL performed the stem cell isolations from benign samples PB performed stem cell isolations from tumors CH performed culturing and isolation of stem cells, and NF-κB experiments ... primitive cancer cells PTL induces apoptosis in primitive cancer cells Percent viability of prostate cancer cells and cells from a patient with BPH treated with increasing concentrations of PTL Cells ... interactions and stem cell self-renewal Results Identification of gene products associated with a cancer stem cell phenotype By comparing RNA expression patterns from stem and committed cells, independent...
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Renewable energy is a challenge, but also an opportunity for new industries, employment, and new ways to reduce dependency on fuel imports, provide electricity to poor remote areas, reduce air pollution
Ngày tải lên :
08/09/2015, 23:32
... Development in Thailand 7.6 Summary of Renewable Energy Potentials and Developments Renewable Energy Developments and Potential in Viet Nam 8.1 Institutional and Policy Framework for Renewable Energy ... Potential of Agricultural Residues: Thailand 7.7 Land Requirement for Palm Oil as Biodiesel Feedstock: Thailand 7.8 Land Requirement for Sugarcane as Bio-Ethanol Feedstock: Thailand 7.9 Land ... of renewable energy developments and potential in Cambodia, the Lao PDR, Myanmar, Thailand, and Viet Nam 11 Renewable Energy Developments and Potential in Cambodia 4.1 Institutional and Policy...
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A proteomic approach for the identification of HCC serum biomarkers
Ngày tải lên :
26/09/2015, 09:47
... 2003; Pollak and Foulkes, 2003) 21 1.1.9 Need for Biomarkers that allow Early Cancer Detection Current screening and diagnostic tests for HCC involve a combination of ultrasound and serum AFP ... of this, there is an impetus to find new biomarkers that are more sensitive and specific for HCC and that can detect HCC early 1.1.9.1 The Search for New HCC Biomarkers In light of the limitations ... Need for Biomarkers that allow Early Cancer Detection 1.1.9.1 The Search for New HCC Biomarkers 1.1.10 The Ideal Biomarker 1.2 TUMOUR IMMUNOLOGY 22 22 24 25 1.2.1 The Humoral Response to Cancer...
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Báo cáo khoa học: " Copeptin: a new and promising diagnostic and prognostic marker" pdf
Ngày tải lên :
13/08/2014, 10:20
... hormone and cortisol Serum cortisol levels have been reported to be proportionate to the degree of stress and, by mirroring the individual stress level, to predict outcome in sepsis and pneumonia ... hypotension and ongoing vasopressor drug requirements [15] or in patients with electrolyte disturbances 11 Of course, any biomarkers will always oversimplify the interpretation of important variables, and ... interpretation of important variables, and therefore biomarkers are meant to complement, rather than to supersede, the judgment of clinicians and/ or validated clinical severity scores Conceptually,...
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