been as inadequate as current budgets are the longer term future is more troubling still if current spending levels are maintained by some projections the amount of the defense shortfall will be

Báo cáo y học: "Closure of the NCBI SRA and implications for the long-term future of genomics data storage" doc

Ngày tải lên : 09/08/2014, 22:23

... deleted RK: If there is a good chance that the data are going to be used by others, then yes, there is a good case for storing them Just storing the raw data for the sake of it, however, is probably ... ‘reference-based com pres ion’, which will drastically reduce the amount of disk s space per stored sequenced base and hence the cost of that storage Some communities haven’t been well served by the ... For instance, if you’re comparing differences between two genome assemblies you need to be able to go back to the raw reads to check if the differences are real or if it’s just an assembly problem...

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Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"

Ngày tải lên : 02/11/2012, 11:12

... “reassortment” of the genetic material between these viruses The mechanism of this reassortment or conversion is not understood, and has not been replicated in a lab None the less the probability of this ... drift; functional ability of the nueraminidase, and the immunity of the host it infects to fight the virus The first two factors are influenced by the genetics of the virus The last factor is ... in the index in the 1918 volumes of the Journals of the American Medical Association Influenza was not a reportable disease: the only evidence of the early occurrence was the registration of...

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Reading Theory as a Microcosm of the Four Skills

Ngày tải lên : 06/09/2013, 10:10

... some of the more important sub-skills of reading are present in each of the other three skills We have seen how the only difference is in their emphasis It is my belief that in giving the L2 student ... is the task of knowing his clients The notion of needs analysis is absolutely central Even with as few details as we have outlined above, there are certain things that we can assume about this ... this group First, given their age group, it is reasonable to assume that many of them will be students; their needs in English will most predominantly lie in the area of reading University systems...

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Designing listening tasks using authentic materials on websites as supplementary materials for the teaching of listening skills

Ngày tải lên : 07/09/2013, 13:37

... way listening is viewed from different perspectives, they consist of a rather fixed set of tasks As held by Penny Ur, the kinds of the listening tasks are classified by the natures of students’ ... most of the listening tasks for students are self-designed This is the answer of up to 83% of the students when asked There are about 42% of the students who say that their teachers of listening ... ready-made tasks if they are suitable to their sts as they said that sometimes they not have time to modify the tasks All of them confirm that they have never assigned the recordings to their students...

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Seeing things as they really are

Ngày tải lên : 08/10/2013, 15:56

... long for the big change The unsuccessful misfit of diversification should be put out of its misery as fast as possible.” 4 “Already we are beginning to deliver more lectures and classes off campus ... and be managed out of one place, like Atlanta,” he says If not the big S&P companies, which, then, will be the global outfits of the future? Chinese clans The Chinese are likely to make the ... this “These are the official forecasts, not mine The birthrate is not increasing The reproductive rate is down to almost in southern Europe and about 1.5 in Japan,” he says He rattles off official...

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Idioms with as as in comparison with the vietnamese ones = nghiên cứu thành ngữ so sánh trong tiếng anh và tiếng việt

Ngày tải lên : 19/12/2013, 10:39

... fawn as devoted as a mother as lazy as a pig as lazy as a toad as obstinate as mule as wise as an owl as trick as a monkey as mean as a miser as stupid as a donkey as stupid as a pig as cold as ... as cold as acorpse as cold as ice as sweet as honey as sweet as sugar as agile as a cat as nimble as a squirrel as quick s as lightning as fleet as the wind as warm as sunbeams as blunct as the ... cảm nh tảng đá as still as death as still as a log as drunk as a lord as drunk as a begger as bold as brass as bare as stone as dumb as an an oyster as dumb as a mouse as unfeeling as rocks 2.3...

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Báo cáo khoa học: Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase docx

Ngày tải lên : 07/03/2014, 21:20

... property of these coenzyme analogues would be reasonably explained by the fact that adenine-anchored radicals are formed by photolysis of their Co-C bond and kept associated with the active site The ... dehydratase in the presence of substrate (propane-1,2diol), the spectra of analogues underwent bathochromic shifts of the a-band by 10–20 nm (Fig 3F–H) as compared with those of free counterparts The ... dehydrogenase-NADH coupled method, as described in the text The amounts of apoenzyme used are given below in parentheses Reactions were initiated by adding each coenzyme at a concentration of 10...

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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Ngày tải lên : 08/03/2014, 10:20

... concentration of oxyHb with time was utilized as a measure of the rate of oxidation of oxyHb RESULTS The effect of pH on the auto-oxidation of cross-linked Hb was studied The rate of decrease of the concentration ... presence of EDTA The rough S minnesota LPS increased the initial fast phase of the reaction, but decreased the rate of the slow phase of oxidation in the presence of EDTA A comparison of rough and ... A0 may be in the binding of the deoxyHb to the LPS Another obvious difference between the two Hbs is the possibility of dissociation of the Hb A0 into dimers, which is not possible for the cross-linked...

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Relational Cloud: A Database-as-a-Service for the Cloud potx

Ngày tải lên : 16/03/2014, 16:20

... weight of the cut edges This minimization corresponds to ﬁnd a partitioning of the database tuples that minimizes the number of distributed transactions The output of the partitioner is an assignment ... in the cloud is the perceived lack of privacy, which in turn reduces the degree of trust users are willing to place in the system If clients were to encrypt all the data stored in the DBaaS, then ... 12× when we skew the load (i.e., 50% of the requests are directed to one of the 20 databases) The key reason for these results is that a single DBMS is much better at coordinating the access to...

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Báo cáo Y học: The S100A8/A9 protein as a partner for the cytosolic factors of NADPH oxidase activation in neutrophils doc

Ngày tải lên : 18/03/2014, 01:20

... analyzed the effect of S100A8/A9 on the kinetics of oxidase activation The oxidase activity elicited in the cell-free system was the reflect of the extent of oxidase activation The experiment of Fig ... concentration of Fba It followed that the oxidase activity (v) should reach a maximal value (V) when the totality of the flavocytochrome (Fbt) is activated On the basis of this hypothesis, the first ... determined for each assay of oxidase activation [12] The rate of O2– production by the activated NADPH oxidase was calculated from the rate of the superoxide dismutase-inhibitable reduction of ferricytochrome...

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microsimulation as a tool for the evaluation of public policies potx

Ngày tải lên : 19/03/2014, 00:20

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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt

Ngày tải lên : 20/03/2014, 03:20

... corticoid Lipomodulin (-) phospholipase phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien A leucotrien ... Prostacyclinsynthetase leucotrien A leucotrien B prostacyclin (PGl2) PG-synthetase PG sơ cấp (PGE2, D2, P2) TX synthetase TX A2 leucotrien C TX B2 leucotrien D Dới đây, xin điểm qua số chất nguồn ... làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức chế tyrosin - kinase ngời ung th, ức chế phát triển khối u, làm tăng thời...

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Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx

Ngày tải lên : 22/03/2014, 17:20

... two cell types has been hypothesized, a parent population known as hemangioblasts [38,39] Using the differentiation of mouse ESC as an in vitro model, Keller’s group isolated blast colony-forming ... accepted and has been described in Drosophila, zebrafish and mice [41–43], identification of a human hemangioblast in vivo has not yet been achieved, and is hindered largely by the difficulty of obtaining ... tool for the study of hematopoiesis during embryonic development in states of health or disease [11–13] There is hope that the insights gained by better understanding embryonic hematopoiesis can...

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Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot

Ngày tải lên : 23/03/2014, 05:22

... ﬁve different areas from three different plates were analyzed to measure the length of the processes The sum of the lengths of all the measured processes was divided by the number of cells Cells ... respective genes are present in the cell genome because it would be an extreme coincidence that the rest of each gene had been missed Analysis of the respective mRNAs by RT-PCR, using the same primers, ... structures This is consistent with the lack of microtubule-stabilizing MAPs in these cells The hypothesis underlying most of the numerous experiments that have been performed to elucidate the physiological...

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Engaging Russia as Partner and Participant- The Next Stage of NATO-Russia Relations pdf

Ngày tải lên : 29/03/2014, 20:20

... region,” and the eight areas singled out for cooperation had almost all been in the list of 19 areas of cooperation for the PJC: “ [the] struggle against terrorism, crisis management, non-proliferation, ... areas need to be emphasized in terms of the “European” dimension of work to be done In some of these areas, efforts are already in train; in others, not yet We discuss them in the following sections ... has opened up some NATO standardization agreements (STANAGS) to Russia, which has adopted some of them More will be needed As this happens, the West will need to address the problem of releasing...

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the truth about human origins an investi gation of the creationevolution controversy as it relates to the origin of mankind

Ngày tải lên : 01/06/2014, 11:24

... to the cheek teeth (as is the case in man) They believe the shape of the jaw was parabolic, as in humans, rather than U-shaped, as in most apes And because of some other subtle anatomical distinctions ... It is from the level of the superfamily onward that most of the present debate over the classification of humans begins In a December 4, 2001 article titled Is It Time to Revise the System of ... that on the basis of tooth-size calculations there appears to be little basis for classifying the dryopithecines in more than a single species, Dr Eckhardt went on to say: “Neither is there compelling...

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the american banker as international investor have the new banking powers in the united states increased the volatility of lending into emerging economies

Ngày tải lên : 03/06/2014, 02:14

... would be today It is up to me to show them all their support and sacrifice was worth something in the end For now, I wish finishing up this work could redeem some of my past mistakes to them P.S.Y ... comprehensive analysis of the issue - 11 - As will be shown in Chapter Two, U.S bank lending to emerging economies has been unique in that its volatility has been increasing over the past twenty years, ... economies Furthermore, the share of emerging market claims (in total assets) of these reporting banks experiences a drastic downfall as the average size of the bank gets larger As the importance of emerging...

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THE END OF OBSOLESCENCE :THE WEB AS GROUND ZERO FOR THE POST-CONSUMER ECONOMY

Ngày tải lên : 03/06/2014, 18:27

... 1254-1325 “BEATUS” MAP CATALAN ATLAS 1375 PTOLEMY 90-168 RISE OF THE MERCHANT CLASS THE AGE OF EXPLORATION THE RISE OF DEMOCRACY MANIFEST DESTINY ASPIRATIONAL CONSUMPTION SPACE RACE CONSUMERISM TIME ... INTEGRATED INTO THE LIFE OF TRIBE HIDDEN VALUE IN THINGS WE USED TO DISMISS A MIGRATORY PATH GATHERING OF THE TRIBES CONSTRAINTS BREED INNOVATION REVERENCE III REWIRING THE SYSTEM MIRACLE OF THE COMMONS ... CULTURE Doing More in the Land of Less USING THE WHOLE ANIMAL THE WHOLE CUSTOMER Needs Transactions Emotions Ideas Expertise Engagement Quality Assurance Social Network THEMES OF THE BUFFALO CULTURE...

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báo cáo hóa học:" Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis" docx

Ngày tải lên : 18/06/2014, 15:20

... microscope was used to quantify the number, average diameter, and position coordinates of metastases Percentage of liver volume occupied by metastases and metastases density (foci number/100 mm3) ... from the analysis using Viaprobe (Becton Dickinson, Spain) Statistical Analyses Data were expressed as means ± SD Statistical analysis was performed by SPPS statistical software for Microsoft ... However, this mechanism may require the LFA-1-stimulating microenvironment created by the early 3D-growth of cancer cells preceding angiogenesis in the pathogenic cascade of the hepatic metastasis process...

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báo cáo hóa học: " Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults" pptx

Ngày tải lên : 18/06/2014, 22:20

... promoting quality of life in older adults The data were collected by Statistics Canada under the authority of the Statistics Act Access to the data was granted by Statistics Canada based on a peer-reviewed ... Canada Classification of chronic conditions The respondents were asked to indicate whether they had a disease or another health condition diagnosed by a health professional that had lasted, or was ... pulmonary disease (COPD), diabetes, heart disease, cancer, stroke, urinary incontinence, Crohn's disease or colitis, Alzheimer's disease or other dementia, Parkinson's disease, multiple sclerosis Excluded...

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