a mutagenesis approach for the study of the structure function relationship of human immunodefic

Báo cáo khoa học: "A Clustering Approach for the Nearly Unsupervised Recognition of Nonliteral Language" pdf

Ngày tải lên : 24/03/2014, 03:20

... Nonliteral precision and recall are deﬁned similarly Average precision is the average of literal and nonliteral precision; similarly for average recall For overall performance, we take the f-score of ... of average precision and average recall We calculated two baselines for each word The ﬁrst was a simple majority-rules baseline Due to the imbalance of literal and nonliteral examples, this baseline ... algorithm and then determine the effects of each enhancement The results are shown in Figure The last column in the graph shows the average across all the target verbs On average, the basic TroFi algorithm...

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báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

Ngày tải lên : 18/06/2014, 15:20

... purposed the assessment of the migration capacity of the cells At the moment there is no consensus in establishing acceptance criteria for the migration capacity of BM-MNC in cardiac regeneration ... invalid value, based on acceptance criteria, was observed in the first run for the 1:10 dilution The results of the validation assay are reported in Table Page of (page number not for citation ... and coordination All the authors read and approved the final manuscript References Regulation (EC) No 1394/2007 of the European Parliament and of the Council of 13 November 2007 on advanced therapy...

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Báo cáo khoa học: "A multidisciplinary approach for the treatment of GIST liver metastasis" docx

Ngày tải lên : 09/08/2014, 07:21

... The mainstay of surgical therapy in primary or metastatic disease is to achieve a complete resection with negative margins [7] Conventional chemotherapy and radiation therapy may have minor adjunctive ... Kubota K, Makuuchi M, Kusaka K, Kobayashi T, Miki K, Hasegawa K, Harihara Y, Takayama T: Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional ... colorectal liver metastases Am J Surg 2003, 185:221-229 Kawasaki S, Makuuchi M, Kakazu T, Miyagawa S, Takayama T, Kosuge T, Sugihara K, Moriya Y: Resection for multiple metastatic liver tumors after...

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Báo cáo y học: "A new approach for the large-scale generation of mature dendritic cells from adherent PBMC using roller bottle technology" ppt

Ngày tải lên : 11/08/2014, 10:23

... without fixation Immediately before FACS analysis µg/ml 7-ADD was added as viability indicator The dot plots shown the total cells in the floating fractions with the CD83+, 7-AAD- and CD83+, 7-AAD+ ... from the original DC donor were also used as stimulators as a control The average cpm and standard deviation of triplicate cultures are shown for each stimulator type static flasks In both cases, ... surface area used during the loading process in the bottles allows the monocytes to roll along and stay in close contact with the surface and then eventually attach This is akin to the attachment...

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Báo cáo y học: "A systematic approach for the identification of novel, serologically reactive recombinant Varicella-Zoster Virus (VZV) antigens" ppsx

Ngày tải lên : 12/08/2014, 04:20

... codon)-3’ and the “second round PCR” (one -for- all) primer set: One -for- all-forward: 5’-GGGGACAAGTTTGTACAAAAAAGCAGGCT-3’ and One -for- all-reverse: 5’-GGGGACCACTTTGTACAAGAAAGCTGGGTC-3’ PCR products containing ... in large scale as described by Soutscheck et al [12], rearranged in line assay format and validated with a number of pre-characterized serum samples These validation data confirmed the seroreactivity ... development and validation of VZV antigens in Line format AL, JH, HN and GJ participated in the design of the study AB conceived the study, and participated in its design and coordination and wrote the...

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Báo cáo y học: "A comparative approach for the investigation of biological information processing: An examination of the structure and function of computer hard drives and DNA" doc

Ngày tải lên : 13/08/2014, 16:20

... organizational properties may be the same The polyfunctional nature of RNA has already been alluded to; similarly, DNA, in what has Page of 29 D’Onofrio and An Theoretical Biology and Medical ... percent of eukaryotic DNA, does not appear to participate in the “classic” Watson and Crick role of DNA as an information repository for protein synthesis; therefore the majority of human DNA appears ... and access of biological information via the DNA transcription machinery One of the limitations of the Central Dogma (and, for that matter, the abstract description of a digital computer as a Von...

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Báo cáo sinh học: "Therapeutic dendritic cell vaccine preparation using tumor RNA transfection: A promising approach for the treatment of prostate cancer" pps

Ngày tải lên : 14/08/2014, 19:22

... significant clinical benefits like disease stability in 80% of patients after 2–3 doses of vaccine The mean survival rate was 13 months for melanoma patients and months for renal cell carcinoma patients ... very small prostate tumors This, in association with radical prostatectomy and radiation therapies, has contributed to increasing the curative indexes [2] After several years of primary therapy, ... metaanalyses of ten clinical trials in melanoma patients (167 patients total) These data support mature DCs as the best choice for conducting clinical trials We prepared DC vaccines using allogeneic...

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A proteomic approach for the identification of HCC serum biomarkers

Ngày tải lên : 26/09/2015, 09:47

... Tanaka et al., 2006; Twu et al., 1993) ; and upregulating amongst other signaling pathways, the Ras-Raf-MAPK signal transduction pathway, the JAK/STAT pathway and the protein kinase B pathway ... presentation of HCC, where the dearth of symptoms at the early stage of the disease results in detection of cancer only when at an advanced stage (Usatoff and Habib, 2002) Another is the paucity of ... proteins that reacted with normal and patient sera 76 4.1 Autoantigens that make up a TAA panel that enable early detection of HCC as well as risk stratification of HCC patients 92 4.2 Criteria for...

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A unified approach for the performance analysis of unitary spare time block codes

Ngày tải lên : 26/09/2015, 10:51

... longer applicable and other approaches are needed Such an approach is presented in the next chapter, which presents a uniﬁed approach to evaluating the performance of STBC in the presence of channel ... achieve the maximum possible transmission rate for any number of transmit antennas using any arbitrary real constellation such as PAM For an arbitrary complex constellation such as PSK and QAM, ... channel estimation can be analyzed using quadratic form of a CGRV Later we will show that this approach can even be applied in the case of imperfect channel estimation 4.3 Quadratic Form of a CGRV...

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A Planning Approach for the 21st Century Air Force pot

Ngày tải lên : 07/03/2014, 15:20

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Working PaPer SerieS no 1150 / January 2010: Do bank loanS anD creDit StanDarDS have an effect on outPut? a Panel aPProach for the euro area doc

Ngày tải lên : 15/03/2014, 10:20

... 8765 Bank of Albania, Sheshi “Skënderbej”, No.1 Tirana, Albania; e-mail: kadareja@yahoo.com © European Central Bank, 2010 Address Kaiserstrasse 29 60311 Frankfurt am Main, Germany Postal address ... perception of risk by …nancial intermediaries.6 All in all, the fact that monetary policy can a ect the balance sheets of banks and detailed description of the role of banks in the monetary policy transmission ... area where bank …nancing is the predominant means of …nancing for non-…nancial corporations For example, by the end of 2007 bank loans to the private sector In the euro area banking sector balance...

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Báo cáo toán học: "A Colorful Involution for the Generating Function for Signed Stirling Numbers of the First Kind" pps

Ngày tải lên : 08/08/2014, 01:20

... suﬃces Acknowledgments The author thanks Herbert Wilf and Janet Beissinger, who was the ﬁrst to explore [1] combinatorial proofs using colored permutations, for their assistance References [1] Janet ... Colorful proofs of generating function identities Unpublished notes, 1981 [2] Richard P Stanley Enumerative combinatorics Vol 1, volume 49 of Cambridge Studies in Advanced Mathematics Cambridge ... Mathematics Cambridge University Press, Cambridge, 1997 With a foreword by Gian-Carlo Rota, Corrected reprint of the 1986 original the electronic journal of combinatorics 17 (2010), #N2 ...

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Báo cáo hóa học: "Research Article A Decentralized Approach for Nonlinear Prediction of Time Series Data in Sensor Networks" pptx

Ngày tải lên : 21/06/2014, 17:20

... terms of measure of similarity in X, as the kernel value is larger the closer together two locations are Two typical examples of radial kernels are the Gaussian and Laplacian kernels, deﬁned as ... Shapes of the Gaussian and the Laplacian kernels around the origin more classical and universal ones In this paper, without any essential loss of generality, we are primarily interested in radial ... the temperature as a function of location and time, μ and C the density and the heat capacity of the medium, k the coeﬃcient of heat conduction, Q(x, t) the heat sources, h the convective heat...

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Báo cáo hóa học: " Research Article A Practical Approach for Simultaneous Estimation of Light Source Position, Scene Structure, and Blind Restoration Using Photometric Observations" pot

Ngày tải lên : 21/06/2014, 22:20

... many of the other researchers We then estimate the scene structure and the blur parameter and restore the image The blur function is modeled as Gaussian and the surface gradients are modeled as ... source an image is captured, thus obtaining a set of images as observations If a Lambertian surface is assumed, the image irradiance equation relating the surface gradients and image intensity can ... relative motion between the camera and the object, the PSF remains same for all the observations We also assume that the blur is space-invariant, and hence a single blur mask is assumed for the...

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Báo cáo hóa học: "A UNIFYING APPROACH FOR CERTAIN CLASS OF MAXIMAL FUNCTIONS" pot

Ngày tải lên : 22/06/2014, 22:20

... theorem, Journal of the Mathematical Society of Japan (1951), 296–305 Ahmad Al-Salman: Department of Mathematics, Faculty of Science, Yarmouk University, Irbid, Jordan E-mail address: alsalman@yu.edu.jo ... coeﬃcients of the polynomial P A special class of radial weights that have received a considerable amount of attention is the class of power weights |x|α For background information and related results ... (3.5) We may assume that P does not contain |x|d+1 as one of its terms By dilation invariance, we may also assume that a = |α|=d+1 (3.6) A unifying approach for certain class of maximal functions...

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Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases potx

Ngày tải lên : 23/03/2014, 12:20

... containing pmol of each primer (5Â-ATGAACA AAAATCAAAAAGTAACTATT-3Â and 5Â-TTACCAT TGGTAATGATTAACTCCTCC-3Â), 100 ng template DNA, 0.2 mM of each dNTP, 10 mL 10ã Pfu buffer and U Pfu DNA polymerase ... peptidase mechanisms [42,44] The study of the effect of pH on enzyme inactivation allows the calculation of the pKa of the His176 side chain involved in the inactivation reaction The rate of inactivation ... despite a lack of signicant sequence similarity with the caspases, the gingipain catalytic domain adopted the caspase-like fold [35] The cleaved form of clostripain, lacking the internal nonapeptide...

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Báo cáo y học: "What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?" ppsx

Ngày tải lên : 12/08/2014, 23:21

... synthesis purification and characterization of six Tat variants J Biol Chem 1999, 274:11473-11478 Ranga U, Shankarappa R, Siddappa NB, Ramakrishna L, Nagendran R, Mahalingam M, Mahadevan A, Jayasuryan ... Venkatramanan M, Venkatesh P, Janki MV, Jayasuryan N, Desai A, Ravi V, Ranga U: Transactivation and signaling functions of Tat are not correlated: biological and immunological characterization of HIV-1 subtype-C ... indicate that the second exon of Tat is important to the stability of the structure The last NMR study of Tat to be reported was the first report of a NMR structure for a full-length Tat and was...

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Báo cáo y học: " A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus" docx

Ngày tải lên : 13/08/2014, 05:21

... 5'-ATGGATTATCAAGTGTCAAGTCCAATCTAT-3' (sense,1st–30th); and CCR5CR, 5'-TCACAAGCCCACAGATATTTCCTGCTCCCC-3' (antisense, 1,001st–1,030th) [NM000579] CXCR4: CXCR4CN, 5'-ATGGAGGGGATCAGTATATACACTTCAGAT-3' ... 1st–30th); and CXCR4CR, 5''TTAGCTGGAGTGAAAACTTGAAGACTCAGA-3' (antisense, 979–1,008th) [NM003467] FPRL1: FPRL1CN, 5'ATGGAAACCAACTTCTCCACTCCTCTGAAT-3' (sense, 1st–30th); and FPRL1CR, 5'-TCACATTGCCTGTAACTCAGTCTCTGCAGG-3' ... CC-CKR-5 Nature 1996, 381:647-648 Murakami T, Nakajima T, Koyanagi Y, Tachibana K, Fujii N, Tamamura H, Yoshida N, Waki M, Matsumoto A, Yoshie O, Kishimoto T, Yamamoto N, Nagasawa T: A small molecule...

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Comparatives study on sequence structure function relationship of human short chain dehydrogenases reductases

Ngày tải lên : 23/10/2015, 15:38

... for visualization the results from the study of Consurf and Talana Rastop was available at (http://www.geneinfinity.org/rastop) Tools for studying correlated mutation Talana was available at (http://www.bioware.republika.pl/) ... (http://atama.wnb.uz.zgora.pl/~jleluk/software/wlasne/ssssg/ssssg.zip) Tools for studying mutational variability: Consurf was available at (consurf.tau.ac.il) Talana was available at (http://www.bioware.republika.pl/) Tools for ... information [1] Basically, the aims of bioinformatics are three folds: The first aim of bioinformatics helps to organize the data in an easier way for researchers to access existing information and...

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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

Ngày tải lên : 14/02/2014, 22:20

... significantly different cold-acclimation capacities, we prove that mathematical modelling of metabolism and validation by experimental data offers an attractive possibility for the study of complex ... slightly lower mean rates of carbon uptake before and during the first day of cold acclimation After days of cold exposure, the mean rate of carbon uptake was significantly lower for C24 than for Rsch ... T, Sawodny O, Ederer M & Heyer AG (2010) Mathematical modelling of the central carbohydrate metabolism in Arabidopsis thaliana reveals a substantial regulatory influence of vacuolar invertase...

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