lâm sàng và cận lâm sàng
- Có mối tương quan thuận giữa nồng độ vitanin D huyết thanh với canxi máu toàn phần (r = 0,319; p = 0,021), albumin máu (r = 0,473; p = 0,015), protein máu toàn phần (r = 0,331; p = 0,01), nồng độ bổ thể C3 (r = 0,48, p < 0,001). - Nồng độ vitamin D huyết thanh có mối tương quan nghịch với nồng độ
protein niệu 24h với r = -0,286, p = 0,04.
- Có mối tương quan nghịch giữa nồng độ vitamin D huyết thanh với nồng độ anti ds-DNA (r = -0,311, p = 0,025).
- Nồng độ vitamin D huyết thanh có mối tương quan nghịch với chỉ số hoạt động bệnh theo SLEDAI (r = -0,311, p = 0,025).
1. Nên xác định tình trạng thiếu hụt vitamin D huyết thanh và bổ sung vitamin D ở bệnh nhân VTL ngay từ khi chẩn đoán.
2. Cần có những nghiên cứu theo dõi dọc để so sánh sự khác biệt trước và sau bổ sung vitamin D cho bệnh nhân VTL.
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