the structural assessment of glycosylation sites database sags an overall view on n glycosyl

Báo cáo khoa học: The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity pot

Ngày tải lên : 23/03/2014, 13:20

... (green) and the human DPP-IV (orange) (B) Superposition of the active and speciﬁcity sites of the S9 enzymes porcine POP (cyan) and human DPP-IV (orange) The stacking with the substrate proline ... valine-pyrrolidide in the PepX active site Here a unique bond is observed between the carboxyl group of the ligand and the NH2 of Asn470 (equivalent to Asn710 in DPP-IV) Another potential bond can be proposed ... between the OH atom of Tyr380 and the carbonyl group of the ligand Finally, the valine side chain of the ligand, pointing towards the active site cavity, shows only low hydrophobic interaction with...

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A STUDY ON THE STRUCTURAL FEATUES OF ENGLISH NEWS STORY.DOC

Ngày tải lên : 02/09/2012, 11:12

... learning, we can have some basic knowledge in getting information from news stories in newspaper written in the international language, English, then develop the ability in translation and many ... remember only 12 words, of which 10 in the first half and in the second one Such a sentence can exist only when each half of it is an independent unit of information Under that circumstance, the reader ... analysis, transferring, restructuring and testing Analysis consists of essentially of determining the meaning of the whole story In other words, all the content of the story must be considered in analysis...

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A STUDY ON THE STRUCTURAL FEATUES OF ENGLISH NEWS STORY

Ngày tải lên : 21/12/2013, 14:47

... analysis, transferring, restructuring and testing Analysis consists of essentially of determining the meaning of the whole story In other words, all the content of the story must be considered in analysis ... difficulties and strategies in translating news story Part C is the Conclusion of the study in which I give a summary of major findings, an identification of limitation of the study and an exploration Trinh ... that form the environment around us, it be in local or regional or national or international level The main conveyor of news is newspaper Neither the advent of television nor that of internet could...

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Báo cáo Y học: Monitoring the structural consequences of Phe12 ﬁ D-Phe and Leu15 ﬁ Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf

Ngày tải lên : 17/03/2014, 10:20

... corresponding to the side chain (Cb of an L-valine) The protons of the two CbH3 groups were found to be chemically and magnetically nonequivalent and to yield two different resonances in the region ... dbN(i,i + 3) [39] Fig Analysis of NMR-derived data (A) Schematic representation of the sequential and medium-range NOE connectivities involving NH, a- and b-protons The thickness of the bar indicates ... this fragment, experimental coupling constant values are measured between and Hz (Fig 2B), suggesting conformational averaging over the contributing conformations [27] On the other hand, the helix-promoter/stabilizer...

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Báo cáo khoa học: "INIGATION OF PROCESSING STRATEGIES FOR THE STRUCTURAL ANALYSIS OF ARGOMF" pdf

Ngày tải lên : 17/03/2014, 19:21

... B22 Once attached, it can only be moved once - in B21, if it is son to current NEN Once it is moved, it is no longer a son of the current L (since L doesn't change in B2) and can never be son of ... connections between nodes are coherence relations subordinating relations between father and son, and co-ordinating relations between brothers In C~?~, ,on to both designs is the proposal to construct ... aid in the processing of an arg~uent by restricting the possible interpretation of the proposition containing the clue, and hence facilitating t h e analysis for that proposition As outlined in...

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Báo cáo khoa học: Alternative binding proteins: Anticalins – harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities pdf

Ngày tải lên : 23/03/2014, 07:20

... reagent [7] The reason for the disappearance of the stationary ligand fluorescence seems to be an ultrafast electron transfer between the excited fluorescein dianion and a Trp side chain in the binding ... targets involved in the regulation of the immune response and inflammation as well as neoangiogenesis Another promising drug candidate is an anticalin with strong antagonistic activity towards VEGF ... both anticalins, the set of four loops at the entrance to the ligand pocket exhibited pronounced conformational differences in comparison with each other and with the BBP These structural changes...

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Báo cáo khoa học: The structural basis of calpain behavior pptx

Ngày tải lên : 23/03/2014, 10:21

... phosphorylations of calpastatin, calpains and targets The following Minireviews develop three themes on the role of calpain and in cytoskeletal anchorage and sarcomere stability, on the speciﬁc ... Etudes in Paris ` His doctoral work on the evolution of muscle kinases was conducted at the College de France in Paris In 1977 he joined the National Center of Scientiﬁc Research (CNRS) in Montpellier ... The structural basis of calpain behavior Y Benyamin two parts, DIIa and DIIb, come closer together, with concomitant release of constraints between the domains (large arrows) This active conformation...

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THE STRUCTURAL CHANGE OF GLOBAL FOREST INDUSTRY docx

Ngày tải lên : 24/03/2014, 05:20

... harbour the same amount than the roundwood needed for producing one ton of pulp in Finland 23 Deman and Supply Impacts So Far In the 20th century, a rapid increase in forest products consumption and ... costs Transportation costs (distance to markets) 21 The annual growing period is long and productivity high in Brazilian eucalyptus plantation compared to the planted birch forest in Finland 22 ... emerging economies Ex packing paper demand in OECD-countries vs Asian emerging economies Specific and subsitute factors can result to radical and rather speedy changes in demand Ex Newsprint demand...

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Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

Ngày tải lên : 31/03/2014, 09:20

... are in progress to understand the nature of the PufX54* mutant In conclusion, our data indicate that both the N- and C-terminal portions of the PufX protein play a complex role in organizing the ... depends on the redox state of the ubiquinone pool and on the ubiquinone/RC stoichiometry [2,25] For a normal size of ubiquinone pool (% 25 ubiquinone molecules/RC)1), upon decreasing the ambient ... at transcriptional/post-translational level The PufX54* protein possesses only the N- terminus and the hydrophobic transmembrane helix, whereas the other mutants have in addition part of the C-terminus...

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báo cáo hóa học:" Kinematic assessment of hip movement when retrieving an object from the floor" ppt

Ngày tải lên : 20/06/2014, 04:20

... shares in an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future The authors are not currently applying for any patents ... movement of the lumbar spine and hip joint aiding flexion in technique [8] Kneeling had the least flexion and therefore poses the least risk of hip dislocation Extension Figure shows the mean maximum ... reimbursements, fees, funding, or salary from an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future The authors not hold any...

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báo cáo hóa học:" Kinematic assessment of hip movement when retrieving an object from the floor" pot

Ngày tải lên : 20/06/2014, 07:20

... shares in an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future The authors are not currently applying for any patents ... movement of the lumbar spine and hip joint aiding flexion in technique [8] Kneeling had the least flexion and therefore poses the least risk of hip dislocation Extension Figure shows the mean maximum ... reimbursements, fees, funding, or salary from an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future The authors not hold any...

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THE STRUCTURAL DESIGN OF TALL AND SPECIAL BUILDINGS doc

Ngày tải lên : 21/07/2014, 20:20

... Adjacent to the potential plastic hinge zone (or zones) it may be prudent to have a transition from the full level of confinement, to an intermediate confinement, to low confinement The transition to ... motions, construction of an appropriate nonlinear analysis model, and judicious interpretation of the results Implemented properly, nonlinear dynamic analysis specific to the structural system and ... Modern designs usually concentrate the lateral-force resistance in only a portion of the building framing elements The remainder of the building, commonly known as the ‘non-participating’framing...

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Báo cáo lâm nghiệp: "The effects of thinning on the structural diversity of coppice forests" doc

Ngày tải lên : 08/08/2014, 01:22

... increases the illumination on the stems and in the case of Q faginea this produces an intense sprouting from the stem, instead of the reoccupation of openings through the horizontal expansion ... recreation, environmental preservation), there is an urgent need to study and manage these coppice stands In most cases, thinning is the treatment carried out because it concentrates growth on standing ... of thinning intensity on stand structure These changes are of great importance for forest management For the studied species, moderate and heavy thinning improve the illumination of the crown...

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Báo cáo khoa hoc:"Comparative analysis on the structural features of the 5 ﬂanking region of κ-casein genes from six different species" pot

Ngày tải lên : 09/08/2014, 18:21

... specific expression in transgenic mice [2] The presence of the repetitive LINE and SINE elements in the -flanking region of the ruminants and human κ-caseins may alter transcriptional efficiency [19] It ... Occurence in Rabbit flanking region Occurence in Murine flanking region Table I Occurrence of putative transcription factor binding sites in the region of the murine and rabbit κ-caseins Positions ... for many species, the flanking regions have only been analysed in three closely related ruminant species Identification of DNA sequences involved in the transcriptional control of this gene will...

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Báo cáo y học: "Objective Structured Clinical Examinations (OSCEs), psychiatry and the Clinical assessment of Skills and Competencies (CASC)Same Evidence, Different Judgement" ppsx

Ngày tải lên : 11/08/2014, 15:22

... split into component parts and then meaningfully scrutinised Hodges [32] eloquently argues that the validity of an assessment is intricately linked to and a function of context It is therefore ... Critiques on the Objective Structured Clinical examination Annals of the Academy of Medicine of Singapore; 2005:34:478-82 24 Hodges B, Regehr G, Hanson M, McNaughton N: Validation of an objective ... investigated the validity of the use of OSCEs in clinical examinations of medical students and a full review of all of these is outside the scope of the current discussion In the main, by demonstrating...

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Báo cáo y học: " Assessment of effectiveness measures in patients with schizophrenia initiated on risperidone longacting therapy: the SOURCE study results" ppt

Ngày tải lên : 11/08/2014, 16:20

... conception and design, acquisition of data, analysis and interpretation of data, and drafting of the manuscript and its critical revision for important intellectual content WM was involved in ... months and maintained for 24 months Significant and sustained improvements in negative symptoms and positive changes in mental health quality of life have been reported at month and up to months ... receiving additional antipsychotics other than RLAT However, since the accuracy of information depended on clinician reports, patients other than those documented may have been using additional antipsychotics...

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Báo cáo y học: " Screening for personality disorder with the Standardised Assessment of Personality: Abbreviated Scale (SAPAS): further evidence of concurrent validity" docx

Ngày tải lên : 11/08/2014, 16:22

... interviews were conducted on two different days On the first day, the SAPAS, and all of the non-personality related instruments were administered, and on the second interview day, the AUDADIS, the ... personality disorder were non-significant and low Also shown in table is the Spearman correlation between the SAPAS and the NPI-16, also low (-0.02) Regression of SAPAS on criteria for personality ... planned the current report, MH conducted the statistical analyses, and drafted the manuscript PM reviewed the manuscript, and both authors revised the manuscript several times in conjunction...

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Development of NMR methods for the structural elucidation of large proteins

Ngày tải lên : 11/09/2015, 09:57

... (H)C(C-CO)NH-TOCSY experiments (Table 1.1) correlate proton or carbon resonances within a side chain to one another and to the amide resonances in the backbone They are three-dimensional experiments in ... the amide nitrogen (1 5N) on another, and the carbon chemical shift (13Cα,13Cβ) on the third axis By analyzing the data sets together, the 1HN, 1 5N, 13Cα and 13Cβ spins along the entire backbone ... Preparation of pure protein in solution NMR spectroscopy data processing and analyzing Secondary structure Sequence‐specific resonance assignment Torsion angles Collection of structural restraint ...

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