the role of a security manager in enhancing security in an organization

Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf

Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf

Ngày tải lên : 20/02/2014, 01:20
... state may be maintained mainly by key amino acids. In this study, two point-mutated proteins each with a single base substitution [alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) ] and ... the mutants without tryptophan at 140 (W14 0A and W140O) was much lower than both the wild-type protein and mutants E142O and K13 3A. Thermal analysis of protein unfolding The DSC curves of the wild-type ... investigated. Two point-mutated proteins, with a single base substitution of alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) , and two truncated fragment proteins, with fragments...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

Ngày tải lên : 22/02/2014, 04:20
... Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase Konstantinos Mavromatis 1, *, Iason Tsigos 2, *, Maria Tzanodaskalaki 2 , Michael Kokkinidis 1,3 and Vassilis ... the aromatic ring of Tyr269, and these unfavorable interactions could lead to a decrease of local flexibility and an increased E a value. The validity of the above interpretation was further reinforced ... exhibits an E a almost the same as in the case ofthenativeenzyme(Table1). Thermal inactivation of mutant and wild-type enzymes In order to investigate the effects of mutations on the stability of psychrophilic...
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Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx

Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx

Ngày tải lên : 30/03/2014, 04:20
... ataxia telangiectasia mutated (ATM) ⁄ ataxia telangiectasia and RAD53 related (ATR) kinases at the site of DNA damage may decrease the kinase ⁄ phosphatase ratio and allow the phosphatase to dephosphorylate ... lying in the more stable interaction of the Pph3 phosphatase with cH2AX as opposed to a transient interaction with Rad53p. Abbreviations ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia ... the cisplatin response [9]. Cisplatin interferes with DNA function by causing intrastrand and interstrand cross- linking of nucleotide bases and, in replicating cells, DNA damage usually induces an intra-S-phase...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx

Ngày tải lên : 22/02/2014, 04:20
... amplication betweenC7UandC8L.Primersinitalicswereusedinthegenotyping of allele M. C1U 5Â GAG AGG AAC TGA ACA GAA CAT TG 3Â C1L 5Â CAA CTG CGT ATT AGT GAA GAA TG 3Â C2U 5Â AAT CAA ATT TTA TTA TAA GAC C 3Â C2L 5Â AAT AGC TAA TTA GAG ACC AT 3Â C3U 5Â GGT GTC AAA ... 5Â ATA CAC ACA AAC TCA CAA GG 3Â MWU 5Â CAA CAT ATT TTA AAT AAA ATT GAC AAT 3Â C9LM* 5Â ATA AAA ATG GTA TAC CTC ACT TGT*C 3Â C9UM1 5Â TAA CAA TGA TTC TCT TTC TTT TAG 3Â C9LM1 5Â AAT CTT TAT TTT ... TGG CAC AAC ATT GTA CAT TCT TGG G 3Â C9U 5Â GTA TGG AAG TGT GGA ATA GTT T 3Â C9L 5Â GGA CAC CAC AGA TAT CCA ATA G 3Â C1011U 5Â CAT AAA ACT AAC AAT ACA TGT 3Â C1011L 5Â TAG CAG ATA TTG AAA AGG AG...
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Báo cáo "The role of color luminescence centers Mn, Cu, Co in the semicondutors with wide band gap ZnS, ZnO and their applications " pptx

Báo cáo "The role of color luminescence centers Mn, Cu, Co in the semicondutors with wide band gap ZnS, ZnO and their applications " pptx

Ngày tải lên : 22/03/2014, 11:20
... intensity. As concentration of Mn increases, the intensity of the blue band decreases while the intensity of the yellow-orange band increases gradually and reaches to the maximum at x Mn = ... a blue band at 476 nm, there is one more green band at around 533 nm characterized by Cu 2+ ions (Fig. 3). Intensity of the green band is greater than that of the blue band. As increasing the ... of these two bands are equal to each other and they merge into one wide band ranging from 476 nm to 533 nm. The blue and green bands are characterized by radiation transition of electrons from...
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Báo cáo lâm nghiệp: "Rationalization of the performance of a mobile off-road system working in the forest environment with respect to its emission load" doc

Báo cáo lâm nghiệp: "Rationalization of the performance of a mobile off-road system working in the forest environment with respect to its emission load" doc

Ngày tải lên : 07/08/2014, 10:21
... Dimensional changes in stages (material flows processed by the logging and transport systems), resulting from the changed performance of the system, do not always cause a change in power and material ... suitable machinery, and in using acceptable methods for the employment of machines with the rational performance. Pos- sibilities to determine the rational performance of machines are further ... suitable rational performance. e most important measures compensating the environment con- tamination by extraneous substances are preventive measures that can be applied on a larger part of the...
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Báo cáo khoa học: "The role of Bcl-xL and nuclear factor-kB in the effect of taxol on the viability of dendritic cells" ppsx

Báo cáo khoa học: "The role of Bcl-xL and nuclear factor-kB in the effect of taxol on the viability of dendritic cells" ppsx

Ngày tải lên : 07/08/2014, 23:22
... Morisaki T, Matsumoto K, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Nakamura K, Nakamura M, Katano M. Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma ... agent. J Natl Cancer Inst 1990, 82, 1247-1259. 22. Wiseman LR, Spencer CM. Paclitaxel. An update of its use in the treatment of metastatic breast cancer and ovarian and other gynaecological ... D, Mackay JA, Evans WK. Lung Cancer Disease Site Group of Cancer Care Ontario’s Program in Evidence-based Care. Taxanes as first-line therapy for advanced non-small cell lung cancer: a systemic...
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Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

Ngày tải lên : 09/08/2014, 01:22
... encompass an oxygen-dependent degradation domain, responsible for hypoxic stabilization of α-subunits, and two transactivating domains, namely the amino-terminal transactivating domain and the carboxyl- terminal ... hypoxia may regulate many other features that are important in RA, such as cell trafficking and matrix degradation. An understanding of the biology of the HIF transcription family may eventually ... mediate ubiquitination of various target proteins, and the intracellular domain of the Notch receptor (involved in the maintenance of cells in an undifferentiated state), both of which notably contain ankyrin...
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báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt

báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt

Ngày tải lên : 20/06/2014, 07:20
... Velloso LA, Saad MJ: Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol ... actions of the Akt pathway are more pronounced than the Erk pathway in granulosa cells and vice versa in the in theca cells. None the less, administration of inhibi- tors of these pathways in vivo inhibited ... granulosa and theca cells in com- bination. In summary, this study demonstrates a role for the Akt and Erk pathways in mediating the actions of FSH and IGF on granulosa cells and LH on theca cells in...
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