optimizing a bayesian dose adjustment scheme for a pediatric trial a simulation study

báo cáo khoa học: "Linear versus nonlinear methods of sire evaluation for categorical traits : a simulation study" pps

Ngày tải lên : 09/08/2014, 22:23

... h2: heritability in the underlying scale ; N (0,1) ; ; a standard normal random variate common to all individuals in progeny group i with : N (0,1), and i a standard normal random variate for individual ... implementing the linear analysis in the simulation under the assumptions of a mixed model, was arriving at a meaningful value and from can be readily calculated from In a single population problem, ... sire evaOULLEY luation for categorical variates based on the « thresholdconcept In this approach (GFCAT Gianola-Foulley-Categorical), the probability of response in a given category is assumed...

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báo cáo khoa học: "Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability" pot

Ngày tải lên : 11/08/2014, 12:21

... (AUC) To address these objectives we used simulated data across a wide variety of ORs and frequencies for genetic variants We also carried out an additional simulation based on published ORs and ... macular degeneration simulation Predicted risks of age-related macular degeneration are obtained using logistic regression analysis based on six genetic variants entered as categorical variables ... Gwilliam R, Ahmadi KR, Valdes AM, Arp P, Whittaker P, Verlaan DJ, Jhamai M, Kumanduri V, Moorhouse M, van Meurs JB, Hofman A, Pols HA, Hart D, Zhai G, Kato BS, Mullin BH, Zhang F, Deloukas P,...

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Báo cáo sinh học: "A simulation study on the accuracy of position and eﬀect estimates of linked QTL and their asymptotic standard deviations using multiple interval mapping in an F2 scheme" ppsx

Ngày tải lên : 14/08/2014, 13:22

... value mean 473 Accuracy of multiple interval mapping Table IV Means and empirical standard deviations of dominance and epistatic eﬀect estimates over 100 replicates of simulation model and means ... empirical standard deviations except for the case with a relative QTL variance of 0.25 and marker interval of 10 cM The estimated asymptotic standard deviation also reﬂected the smaller empirical ... standard deviations of the position estimates were again smaller than the empirical standard deviations when the marker density was 10 cM and in comparison showed somewhat larger means and variations...

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Ground reference points adjustment scheme for biped walking on uneven terrain

Ngày tải lên : 09/09/2015, 11:22

... able to walk in a stable manner when it lands on an unexpected terrain features, such as a small pothole, and a small object etc Therefore, it is necessary to have the capability for online adjustment ... continuous Bipedal robot walking can be categorized into three types: statically stable walking, quasi-static stable walking and dynamic stable walking In statically stable walking, the vertical line ... terrain In order to maintain stable walking and avoid falling in spite of unknown disturbances, an online adjustable foot placement is proposed This 28 foot placement takes advantage of available...

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A simulation study of high density magnetic recording scheme with micromagnetic modeling

Ngày tải lên : 26/09/2015, 09:56

... fields for FePt granular media Our results suggest that the rectangular grains can be more closely packed as compared to circular and hexagonal grains Meanwhile, our study indicates that the surface ... grains behave like paramagnetic atoms at high temperature due to thermal agitation [4] The changes of magnetization configuration in magnetic grains will lead to loss of original information For ... Hm array indicate the data to be discarded M(0,0) and H(0,0) refer to the magnetization and magnetostatic field evaluated at the cell a1 40 3.3 Zero-padding scheme applied to N array...

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Adaptive link caching for dynamic source routing a simulation study

Ngày tải lên : 26/09/2015, 10:59

... destination are selected uniformly over the allowed space, and a speed is selected uniformly over [0, vmax ] After arriving at the destination, a node waits at the destination for a pause time, and ... chapter, we propose and evaluate an adaptive link caching scheme for DSR in an ideal case, where nodes can know all information needed to estimate TP ×L(Tp ) immediately Compared to link-static-T ... [2] 12 Chapter Adaptive link caching for DSR: an overview In this chapter, we propose a new adaptive link caching scheme for DSR, which aims to manage the cached link information according to...

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Load unload processes for sub 10NM flying height sliders a simulation study

Ngày tải lên : 10/11/2015, 11:00

... Head-Disk Interface HGA Head-Gimbal Assembly L/UL Load/Unload PSA Pitch Static Attitude RAMAC Random Access Memory Accounting Machine RSA Roll Static Attitude xxvi Load/Unload Processes for Sub-10-nm ... magnetic HDD had a capacity of 100MB, which increased to 1.2GB by 1996 The demand for greater capacity requires the need to increase the areal density The areal density has increased at a rate ... There is a large cavity area, which pulls the particles upwards when they leave the leading pad and enter the cavity area The trailing pad design forms another air stream on its two sides and repels...

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Báo cáo hóa học: " Research Article A Simulation Study: The Impact of Random and Realistic Mobility Models on the Performance of Bypass-AODV in Ad Hoc Wireless Networks" pdf

Ngày tải lên : 21/06/2014, 11:20

... constant at Mbps In each simulation- iteration, we generate a scenario with a source-destination pair that is randomly and uniformly Maximum speed (Vmax ) Packet size Pause time (Tpause ) SDR and ADR ... discard it AODV has a local maintenance scheme to maintain the routes as long as they are active When a link break in an active route occurs, the node upstream of that break tries to repair the ... nonuniform distribution as the simulation time elapses and ﬁnally it reaches a steady state In steady state, the mobile nodes are concentrated at the central region and are almost zero around...

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Báo cáo khoa hoc:" Attenuating effects of preferential treatment with Student-t mixed linear models: a simulation study" docx

Ngày tải lên : 09/08/2014, 18:21

... Production, Armidale, Australia, 1998, vol 25, pp 605-612 [27] Uimari P., Mantysaari E .A. , Repeatability and bias of estimated breeding values for dairy bulls and bull dams calculated from animal model ... replicate of the simulation consisted of a data set generated as per the scheme in figure under the appropriate assumptions of preferential treatment A Bayesian analysis of the data set according ... herd-year variance (values in parenthesis are Monte Carlo standard errors from 000 replicates of the MOET scheme, au= additive genetic variance) Table I Average treatment treatment as a ) h (a 2.3...

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Báo cáo sinh học: " A simulation study of the effect of connectedness on genetic trend" potx

Ngày tải lên : 09/08/2014, 18:22

... replacement policy allows = to take advantage of the best genes by appropriate gene flows Although planned connections are usually hard to establish, at least at the beginning, a rather small amount ... obvious for criteria related to group means The MSE for the average male level per generation x subpopulation decreased gradually when p increased A similar pattern was observed with the standardized ... ¡3rJ to avoid any systematic association between genetic and environmental effects A sire born at generationt had daughters with performance in generationt + The average performance y of n daughters...

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Báo cáo sinh học: "Impact of the use of cryobank samples in a selected cattle breed: a simulation study" potx

Ngày tải lên : 14/08/2014, 13:21

... values for trait A were randomly and independently drawn from a N (0,1) distribution For a given individual (i), the genetic value for trait B (Bi) was generated from its value for trait A (Ai): ... there was a per generation increase in genetic gain for trait B, while there was a slightly lower increase or even a decrease in genetic gain for trait A, as well as in average kinship, when trait ... considered as a functional trait and for functional traits, only animals above the average are considered), - (iii) the bull is a sire of sires with no male offspring selected after the evaluation...

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Báo cáo sinh học: " Linkage disequilibrium ﬁne mapping of quantitative trait loci: A simulation study" potx

Ngày tải lên : 14/08/2014, 13:22

... multiallelic marker loci and QTL for the LD scenario On average, P-values decreased as the distance from the QTL decreased indicating a higher signiﬁcant association Mean P-values also decreased as ... when haplotypes are analysed rather than each marker individually The empirical variances of signiﬁcance levels (P-values) for association between MST markers and the QTL are given in Figure 5A The ... particular allele to the trait but, rather, the global association between all marker alleles and the trait Thus, in the LD scenario we expect that a single allele is associated with the trait,...

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Optimizing a Site for Google

Ngày tải lên : 24/10/2013, 08:20

... or assign a PageRank This page was created with ImageReady, an Adobe program that creates and slices images for deployment on a Web page Although most sophisticated graphics programs allow placement ... example of an all-graphics page that appears to be text Google can’t index this page because it can’t read the words (In this case, the page is an information source for local members of a dance ... dynamic ones ߜ Frames Frames are easier to eliminate than dynamic pages Frames confuse spiders, because each frame on a page behaves like a separate page in some ways For optimization purposes,...

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Báo cáo khoa học: "Jointly optimizing a two-step conditional random ﬁeld model for machine transliteration and its fast decoding algorithm" pdf

Ngày tải lên : 17/03/2014, 00:20

... Dong Yang, Paul Dixon, Yi-Cheng Pan, Tasuku Oonishi, Masanobu Nakamura and Sadaoki Furui 2009 Combining a Two-step Conditional Random Field Model and a Joint Source Channel Model for Machine Transliteration, ... Kumar Naskar and Sivaji Bandyopadhyay 2006 A modiﬁed joint source-channel model for transliteration, Proceedings of the COLING/ACL, pages 191-198 Bo-June Hsu and James Glass 2008 Iterative Language ... Learning, pages 282-289 Haizhou Li, Min Zhang and Jian Su 2004 A joint source-channel model for machine transliteration, Proceedings of the 42nd Annual Meeting on Association for Computational...

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báo cáo hóa học: " A flexible routing scheme for patients with topographical disorientation" potx

Ngày tải lên : 19/06/2014, 10:20

... from architectural drawings A patient table captures vital information about the patient, namely, personal data such as name, age, sex, contact information, and most importantly, individual ability ... turn Database Information pertaining to patient disability, the building layout and environmental barriers along paths of travel are organized into a relational database consisting of three tables ... conventional implementations that rely on a static graph, our approach uses a dynamically changing graph Recall that there is a navigational choice at each node Whenever the user reaches a new node,...

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