neuroprotective and neurotoxic effects of l dopa in rat midbrain dopaminergic neurons in culture

Sun L. 2010-Bank loans and the effects of monetary policy in China-VAR-VECM approach

Ngày tải lên : 18/06/2016, 20:56

... bank lending and interest rate channel mutually We still cannot split the roles played by the bank lending channel and the monetarist channel (i.e., liquidity effects of money supply) in China's ... (growth rate of M2 as indicator) Trend assumption: linear deterministic trend Series: GROWTH_RATE _OF_ M2 LGTDEPOSIT LGINLOAN LGCOMMLOAN LGPROPLOAN LGSECURITIES LGSSINDEX LGIPX12 CPI Lags interval (in ... difﬁcult, most of China's ﬁrms obtain external capital mainly depend on the banks loans The bank lending channel does and will play a great role in the implementation of China's monetary policy...

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báo cáo hóa học: " Dexamethasone diminishes the pro-inflammatory and cytotoxic effects of amyloid β-protein in cerebrovascular smooth muscle cells" docx

Ngày tải lên : 19/06/2014, 22:20

... effectively reduced the levels of IL-6, MMP-2 activation, and loss of smooth muscle α actin, processes that precede HCSM cell death and likely contribute to inflammation and loss of vessel wall integrity ... without daily administration of anti-inflammatory drug (1 μM final concentration) The cell culture medium was collected and the level of IL-6 present in the medium was measured by ELISA analysis The ... was performed in triplicate and five fields were scanned for each well Quantitative immunoblotting For analysis of cellular proteins, the culture medium was collected and the cells rinsed with phosphate-buffer...

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báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx

Ngày tải lên : 19/06/2014, 22:20

... g Pellets were resuspended in neuronal culture medium and aliquots of the cell suspension (10 L/ well) were seeded on top of DIV primary neuronal cultures at a final density of × 10 cells/mL (1.3 ... by lack of C/EBPb Thus, LPS+IFNg-induced mRNA levels of NOS2 and IL-1b were significantly lower in C/EBPb-null than in wildtype cultures TNFa and IL-6 mRNA levels did not differ statistically ... ensure that wild-type and C/ EBPb-null glial cultures were comparable, we first analyzed total cell density and abundance of their two main cell types, astrocytes and microglia, in both cultures No...

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báo cáo hóa học:" Pain in cancer. An outcome research project to evaluate the epidemiology, the quality and the effects of pain treatment in cancer patients" pptx

Ngày tải lên : 20/06/2014, 15:20

... quality of life, generic, disease and treatments specific side effects) , all patients enrolled in the study and eligible will be included in the statistical descriptive analyses To avoid and minimize ... reported level of pain (intensity) and the potency of the prescribed analgesic drug (according to the WHO analgesic ladder) Operationally, self-reported pain intensity (from the BPI) and the level of ... randomised, double-blind, placebo-controlled study Pain Clinic 2003, 15:193-202 Farar JT, Halpern SD: Understanding clinical trials in pain research In Cancer Pain, Assessment and Management Edited...

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Báo cáo y học: "Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study" potx

Ngày tải lên : 13/08/2014, 11:22

... GE, Helsinki, Finland) was used for measurement and storage (via WinCollect® software [Datex-Ohmeda, GE Healthcare, Helsinki, Finland]) of the following parameters: heart rate, arterial blood ... administration of a sedative drug or opiate, clinically indicated endotracheal suctioning, and a combination of both Specifically, we evaluated whether BIS and state entropy monitoring allow ... Critical Care Vol 12 No Haenggi et al ventilation [8,10,11] Accordingly, a reliable, objective assessment of sedation and analgesia during the course of critical illness would be very valuable Ideally,...

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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt

Ngày tải lên : 08/03/2014, 08:20

... homologation of one carbon, such as [Gly9(wCH2CH2CH2)Gly10]SP (D Loeuillet & S Lavielle, unpublished data), led to an analogue completely devoid of binding potency for NK-1 binding sites Interestingly, ... previously from ab initio molecular orbital (MO) calculations and molecular mechanics calculations [11–13] The potential energy surfaces accessible to b-amino acids have plenty of local minima The minimum-energy ... Gln5 remains close to Hz, indicating that Gln5 always adopts a helical conformation This invariable folding of Gln5 is related to the helix initiator propensity of Pro4 and decreases from Gln5...

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Báo cáo khóa học: Assembly of the silk ﬁbroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of a1,2-mannose residues in N-linked oligosaccharide chains of ﬁbrohexamerin/P25 ppt

Ngày tải lên : 16/03/2014, 16:20

... extremely low level of normal L- chain It implies that numbers of the normal elementary unit are assembled in proportion to the available numbers of the normal L- chain, and the N-linked oligosaccharide ... Role of L- chain in the elementary unit of ﬁbroin (Eur J Biochem 271) 361 Table Determination of molar ratios of H-chain, L- chain, and fhx/P25 in the ﬁbroin secreted into cocoons of a normal breed ... sericin) for Nd-sD Proteins from cocoon shells of C108 (2.5 lg; Fig 5, lanes and 5), Nd-sD (200 lg; Fig 5, lanes and 6) and two transgenic lines [L6 · (5 lg; Fig 5, lanes and 7) and H-chain L- chain...

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industry and the effects of climate in italy

Ngày tải lên : 21/03/2014, 22:04

... contains many longitudinal (Valle d'Aosta, Valtellina, Val Venosta and Val Pusteria) and transversal valleys (Val di Susa, Val d'Ossola, Val Camonica and Valle dell'Adige) It can be divided in ... Plain in the continental section; the Apennine system and anti-Apennine reliefs in the peninsula section; and the large islands of Sicily and Sardinia The AlpsAlmost the whole southern side of ... southern Sicily) it falls below 600 mm pa The great internal Alpine valleys and the coastal plains of the Tyrrhenian (Maremma) and Sardinia also receive little rain Altogether, six large climatic...

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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf

Ngày tải lên : 29/03/2014, 00:20

... Other, less well-characterized, inhibitors of ANT have also been reported [37] Mindful of (a) the well-established ligand proﬁle of ANT, (b) the modulatory role of ANT in the mammalian PTP, and ... guidelines The X laevis liver is a melanin-containing organ, owing to the presence of melanomacrophage centers [67]; the presence of melanin in the mitochondrial pellet precluded the reliable calibration ... permeability transition pore? J Mol Cell Cardiol, 46, 821–831 50 Merlini L, Angelin A, Tiepolo T, Braghetta P, Sabatelli P, Zamparelli A, Ferlini A, Maraldi NM, Bonaldo P & Bernardi P (2008) Cyclosporin...

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Báo cáo khoa học: Prohibitin is expressed in pancreatic b-cells and protects against oxidative and proapoptotic effects of ethanol pdf

Ngày tải lên : 29/03/2014, 08:20

... physiologically relevant ethanol level of 80 mm (368 mgÆdL)1) found in the blood of clinically nonintoxicated alcohol drinkers [36] ROS have been implicated in b-cell dysfunction and apoptosis in ... (2002) Stimulation of insulin secretion and associated nuclear accumulation of iPLA(2)beta in INS-1 insulinoma cells Am J Physiol Endocrinol Metab 282, E820– E833 58 Veluthakal R, Palanivel R, Zhao ... insulin-stimulated glucose uptake in isolated rat skeletal muscle: role of Gs alpha and cAMP Alcohol Clin Exp Res 29, 1450– 1456 Patel DG & Singh SP (1979) Effect of ethanol and its metabolites on glucose...

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Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx

Ngày tải lên : 18/06/2014, 16:20

... Cancer Institute of Naples internal guidelines Every months the following assessments were performed for all patients: clinical examination, a regional lymph node ultrasound scan, and an abdominal ... intensities than the CD8+ cells were included in the gate for CD25high cells The gate for CD25low cells was set to include cells expressing CD25 at levels above those of the isotype control and ... Medicine Unit of the National Cancer Institute of Naples were used as controls for the evaluation of basal Treg levels following assessment of samples for infections and other diseases Page of...

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Báo cáo khoa học: "Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats" ppsx

Ngày tải lên : 07/08/2014, 18:21

... in seminiferous tubules H & E stain, ×50 and multiple layering of the tubular endothelium, degeneration of germ cells, and the formation of many multinucleated giant cells in atrophied seminiferous ... There were thickening and multiple layering of the tubular endothelium, degeneration of germ cells, and the formation of many multinucleated giant cells in atrophied seminiferous tubules (Fig 5B) ... acrylamide and/ or glycidamide binding to spermatid protamines causes dominant lethality of gonadal cells and morphological abnormalities of sperms One of the histopathological lesions observed in...

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Báo cáo khoa học: "Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat" pdf

Ngày tải lên : 07/08/2014, 20:23

... presence of scattered inflammatory cells, indicated the presence of foci of inflammatory cells and corresponded to diffuse inflammation The sum of steatosis and inflammation scores was used in the ... Adachi Y, Stachlewitz 37 RF, Zhong Z, Knecht KT, Bradford BU, Mason RP, Lemasters JJ Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury J Gastroenterol ... cycle The room o temperature (22 ± C) and humidity (55 ± 5%) were controlled automatically Laboratory pellet chow (Purina, Korea) and water were given ad libitum All of the animals were acclimatized...

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Báo cáo khoa học: " Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex" doc

Ngày tải lên : 07/08/2014, 23:22

... basalocortical and intracortical NOS neurons are involved in the spatial and temporal regulation of cortical perfusion following basal forebrain activation Aluminium accumulation in the brain can alter ... et al elevated levels of NO that are apparently involved in neurodegeneration by different mechanisms, including oxidative stress and activation of intracellular signaling mechanisms [19] Al affects ... 4.2 L; 2.4 V) [16] L- NAME was immediately injected before the neurotoxin/saline solution For all treated animals, the injected intracerebral volume was 10 l and was always injected into the left...

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Báo cáo lâm nghiệp: "Carbon pool and substitution effects of an increased use of wood in buildings in Switzerland: first estimates" pdf

Ngày tải lên : 08/08/2014, 00:22

... Competing product/substitute Laminated timber board 2-layered brick wall Construction Exterior wall Pillar Ceiling Insulation Roofing Gluelam pillar Steel pillar Ceiling of wood beams Ceiling of ... bricks will lead to a reduction of the GHG emissions in Switzerland Figure illustrates that an increased use of wood for ceilings will develop the highest substitution effects in a global perspective ... the building elements If all the wood that is additionally used in the building stock will be used thermally in specialised wood incinerators, an additional energetic substitution effect of 0.265...

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Báo cáo khoa học: "Growth and morphology of pedunculate oak (Quercus robur L) and beech (Fagus sylvatica L) seedlings in relation to shading and drought" docx

Ngày tải lên : 08/08/2014, 18:21

... predominantly by blue jays (Garrulus glandarius L) and small rodents (Apodemus sylvaticus L and Clethrionomys glareolus Schreber) The probability that acorns and beechnuts will develop into saplings ... thicker fine roots (fig 3) and a smaller proportion in fine root length in relation to seedling biomass (tables I and II) The SRL and fine root length of both species increased as available light ... shelter-pot combination as a block in the analysis of biomass, height and SLA, and with shelter as a block in the analysis of biomass partitioning, leaf area, fine root length and SRL RESULTS...

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Báo cáo khoa học: "Effects of needle clumping in shoots and crowns on the radiative regime of a Norway spruce canopy Alessandro Cescatti" ppsx

Ngày tải lên : 09/08/2014, 04:20

... not always valid In fact, competition-driven self-thinning and silvicultural treatments often induce regular tree distributions in even-aged stands [10], while typical gap dynamics of natural, ... assumption of random tree distribution often adopted in other canopy models [12] The effect of successive levels of leaf clumping on indirect LAI estimates obtained by the LI-COR LAI 2000 plant canopy ... (silviculture and agroforestry [5, 27, 29]) Conifers in particular present successive levels of leaf clumping which may be an architectural strategy for the optimisation of light absorption in...

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$Báo cáo y học: "Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study" doc$

Báo cáo y học: "Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study" doc

Ngày tải lên : 09/08/2014, 08:22

... All these experiments were run in triplicate and the results were expressed as the percent of cell proliferation, according to the following formula: % cell proliferation = (cpm of CD4+CD25plus ... open clinical trial with Rituximab in SLE patients, and evaluated their clinical response as well as its effect on the levels and function of regulatory T lymphocytes and the apoptosis of immune ... CD4+CD25+ regulatory T cells (1 × 104) in the presence of PHA (5.0 µg/ml) and cultured for 72 hours in complete culture medium in 96 well plates 3H-methyl-thymidine (1.0 µCi/well, specific activity...

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Báo cáo y học: "Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models" pps

Ngày tải lên : 09/08/2014, 14:20

... slightly inhibited the phosphorylation of extracellular-regulated kinase (ERK)1/2 in the MAP kinase signaling pathways was slightly inhibited in the presence of piperine (b) The nuclear levels of ... wide range of collagenous and non-collagenous extracellular matrix macromolecules and is remarkably active against collagen type II, the predominant collagen in cartilage To our knowledge, this ... Piperine also inhibited both the protein and mRNA expression levels of IL6 and COX-2 In particular, piperine inhibited the production of PGE2 more potently than the production of IL6 Interestingly,...

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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

Ngày tải lên : 09/08/2014, 14:22

... Cell surface molecule expression Finally, we examined the effects of the chemokines on the expression of the cell surface molecules ICOSL, BAFF-R and TACI by peripheral blood B cells of normal ... chemokines, CCL20, a ligand for CCR6, CCL19 and CCL21, ligands for CCR7, and CXCL12, a ligand for CXCR4 First, we analyzed the effects the chemokines on migration of peripheral blood B cells Each of ... mAb induced B cell proliferation (fold increase: 5.5 ± 0.8) Stimulation with a low concentration of CCL20 (10 ng/ml) decreased the proliferation of anti-IgMstimulated peripheral blood B cells In...

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