mechanisms of pathological vegf production in the retina and modification with vegf antagonists

Báo cáo y học: "Quantifying the major mechanisms of recent gene duplications in the human and mouse genomes: a novel strategy to estimate gene duplication rates" docx

Ngày tải lên : 14/08/2014, 08:20

... as the cut-off and fitted linear models to each part of the curves The results are shown in Table The slopes of the linear functions are therefore the estimates of gene duplication rates for the ... retroposition The rates are the slopes of the linear functions (red lines) fitted to the curves of the cumulative distributions of retrogenes All of the linear functions are fitted to the part of the curves ... distributions of the cumulative number of duplicated genes in TAGs as a function of Ks were plotted in R [46] in both two-copy gene families and in the entire genome The interval of the data points in terms...

11
357
0

Báo cáo y học: " Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage" ppt

Ngày tải lên : 12/08/2014, 23:23

... binding sites upstream of the NF-KB binding site are essential for the efficient transcription in monocytes and macrophages In addition to NF-KB and Sp1 binding, NF-IL6 and/ or USF protein binding ... correlate with an increase in anti-apoptotic Bcl-2 and Bcl-XL proteins and a decrease of pro-apoptotic Bax and Bad proteins [139] The role in apoptosis of viral proteins is often dual The protein Nef ... promoter increases the production of the p21 protein, a cell cycle regulator Consequence of such block in cell cycle is an enhancement of the viral transcription The binding of CTIP2 to the p21...

16
299
0

Báo cáo y học: "Theoretical analysis of the mechanisms of a gender differentiation in the propensity for orthostatic intolerance after spaceflight" docx

Ngày tải lên : 13/08/2014, 16:20

... approach to the problem was used to integrate many of the experimental findings in to a more comprehensive theory of understanding [14] The analysis suggested that changes in the capacitance of the lower ... due to their inherent lower center of gravity and proportionately larger mass in the lower extremities Examining the theoretical consistency of the hypothesis in the context of the current considered ... also incorporated into the structure of the mathematical model Since much of the past research on the postflight OI issue has focused on the complex interactions of autonomic, neurohormonal and...

8
337
0

Novel mechanisms of programmed cell death in the protozoan parasite blastocystis

Ngày tải lên : 16/10/2015, 15:35

... homologs of mammalian molecules involved in cell death signaling are missing in the protozoa and the molecular architecture of PCD in protozoan parasites therefore remains puzzling The kinetoplastid ... Madam Ng Geok Choo and Mr Rama for their tireless efforts in maintaining the smooth functioning of the lab I am greatly indebted to Mrs Josephine Howe for her time and help in teaching me transmission ... Objectives of the present study Despite increasing number of studies describing the cytochemical features of PCD in protozoan parasites, knowledge of the mechanism and molecular mediators of PCD in these...

173
382
0

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

Ngày tải lên : 16/02/2014, 15:20

... discovery of a brain-speciﬁc MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain In the ... studies examining the role of GIF in AD, linked to its initial discovery as a factor deﬁcient in the AD brain There remains no clear consensus on the role of GIF in the pathogenesis of AD, and therefore ... exhaustion and eventually cell death, partly explaining the vast neuronal loss in the AD brain Further investigation of the increased neurotrophic activity of the AD brain revealed that it correlated with...

9
664
0

Báo cáo sinh học: " Review of the temporal and geographical distribution of measles virus genotypes in the prevaccine and postvaccine eras" pdf

Ngày tải lên : 19/06/2014, 08:20

... genotypes in the prevaccine and postvaccine eras Methods An examination of the National Library of Medicine "PubMed" [13] search engine using the keyword "measles" combined with "genotypes" and "sequence" ... carboxy terminus of the N protein The entire sequence of the coding region of the H gene should be obtained from representative isolates Additional sources included the reference lists of articles ... Europe, Finland and the UK over the last 40 years Since, it is difficult to distinguish wild-type viruses in genotype A from vaccine strains, these reports must be interpreted with caution since...

9
477
0

báo cáo hóa học:" Review of the temporal and geographical distribution of measles virus genotypes in the prevaccine and postvaccine eras" potx

Ngày tải lên : 20/06/2014, 04:20

... genotypes in the prevaccine and postvaccine eras Methods An examination of the National Library of Medicine "PubMed" [13] search engine using the keyword "measles" combined with "genotypes" and "sequence" ... carboxy terminus of the N protein The entire sequence of the coding region of the H gene should be obtained from representative isolates Additional sources included the reference lists of articles ... Europe, Finland and the UK over the last 40 years Since, it is difficult to distinguish wild-type viruses in genotype A from vaccine strains, these reports must be interpreted with caution since...

9
395
0

Báo cáo nghiên cứu khoa học " SOME TECHNICAL SOLUTIONS SUITABLE FOR DEVELOPMENT OF SMALLHOLDER PIG PRODUCTION IN QUANG TRI AND THUA THIEN - HUE PROVINCES " doc

Ngày tải lên : 22/06/2014, 12:20

... birth and weaning rates In addition, the successful incorporation of biogas production for cooking, composting with earthworms, effluent disposal, integrated farming practices and overall increased ... contents and methodology 2.2.1 Improvement of performance of the local MC pigs by pure breeding program o Introgression the MC breeding sows / males collected from the Northern provinces into the ... located in or near the kitchen with the phibro cement or tole roof of poor ventilation Effect of nestboxes to the number of piglets weaned and the growth ability of piglets - A total of 20 MC...

10
513
2

Báo cáo khoa hoc:"Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels" pps

Ngày tải lên : 09/08/2014, 18:21

... diabetes insipidus in a patient On substitution of the arginine for serine instead of cysteine, binding capacity and function returned to wild-type levels indicating the importance of the cysteine ... J.M., Fressinaud E., Boyer-Neumann C., The arginine-552-cysteine (R1315C) mutation within the A1 loop of von Willebrand factor induces an abnormal folding with a loss of function resulting in type ... that the amino acid change from arginine to cysteine is imparting a functional difference to the leptin molecule One explanation may be that the cysteines presence in the A-helix of the leptin...

12
321
0

Báo cáo khoa hoc:" No evidence of enhanced oxidant production in blood obtained from patients with obstructive sleep apnea" potx

Ngày tải lên : 11/08/2014, 07:21

... patients resulting in the rise of plasma norepinephrine and epinephrine levels [25-27] may perhaps be responsible in the insignificant changes between evening and morning blood LBCL in OSAS patients ... dissimilar potentials in reducing Fe3+ ions, thereby varying along with the time of sample incubation in their contribution to FRAP Therefore, we additionally analyzed the effect of apneas-induced IH events ... evening intensity of the resting as well as fMLP-induced LBCL, FRAP and blood H2O2 activities in the OSAS patients These suggest a lack of apparent ROS overproduction via circulating PMNs in OSAS...

11
347
0

Báo cáo khoa hoc:" No connection between the level of exposition to statins in the population and the incidence/ mortality of acute myocardial infarction: An ecological study based on Sweden’s municipalities" pptx

Ngày tải lên : 11/08/2014, 07:21

... percentage of having an income within the lowest quartile for Sweden in all municipalities, SD2 is standard deviation for having an income within the lowest quartile for Sweden in all municipalities, and ... Change of cut off level of Cardiac troponin T, troponin I or creatine kinase (CK-MB) for AMI Figure Incidence and mortality of acute myocardial infarction (AMI) and statin utilisation in the Swedish ... three years of the study the incidence of AMI decreased in males from 8.37 to 7.81/1000 and then again increased to 8.26 in 2001, followed by 8.06 in 2002 (Figure 1) In women, the incidence decreased...

8
478
0

Báo cáo khoa hoc:" Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment" doc

Ngày tải lên : 11/08/2014, 08:20

... to fasting insulin and glucose levels [13] A weighted combination of fasting insulin and triglycerides [14], 'insulin sensitivity index' (ISI), was also used as surrogate a marker of insulin sensitivity ... Journal of Negative Results in BioMedicine 2006, 5:14 Median (interquartile range) are shown A decrease in HOMA-S and ISI is indicative of a reduction in insulin sensitivity * Changes in insulin sensitivity ... consequential of changes involving signal transduction and glucose transport Circulating levels of TNF alpha show a coordinated increase with obesity during the course of gestational diabetes [21], and...

5
304
0

Báo cáo y học: " “pp65 antigenemia and real time polymerase chain reaction (PCR) based-study to determine the prevalence of human cytomegalovirus (HCMV) in kidney donors and recipients with follow-up studies.”" pptx

Ngày tải lên : 12/08/2014, 02:20

... (64%) of the recipients were not As a result of the increased use of Gancyclovir prophylaxis, the incidence and severity of CMV disease is significantly reduced However, there is an increasing incidence ... Smears were fixed in methanol for 10 minutes Immunofluorescence staining was carried out on the smears using pp65 staining kit obtained from Argene SA, France The smears were stained with mouse monoclonal ... carried out the real time PCR assay JM participated in the design of the study and performed the statistical analysis HNM conceived of the study, and participated in its design and coordination All...

7
399
0

Báo cáo y học: "α The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis" pot

Ngày tải lên : 12/08/2014, 11:22

... polymorphisms in MRL-lpr lupus mice and that enhanced expression of α-actinin may determine the extent of antibody deposition [10] These observations, together with the demonstration that α-actinin immunization ... anti-α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in the prevalence of LN [14] Finally, levels of anti-α-actinin antibodies correlated with those of anti-DNA ... between antinucleosome and anti-dsDNA antibody levels, with each showing a positive correlation with urine protein/creatinine ratio and a negative correlation with serum albumin, these were not...

3
337
0

Báo cáo y học: "Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis" pps

Ngày tải lên : 12/08/2014, 14:22

... panel and (iii) in the right panel The right panel shows increased number of peaks in CD204 histogram in SSc patients The number of peaks is shown on the ordinate * P < 0.05 as compared with the ... YY, and FCM assisted in the study design, oversaw the project running and data analysis, and drafted the manuscript TM, SF, YI, YK, and HM assisted in the study design and coordination, and oversaw ... for 15 minutes at room temperature in the dark For intracellular staining, the cells were fixed and permeabilized according to manufacturer's instructions using Intra Prep (Beckman Coulter Inc,...

10
214
0

Báo cáo y học modulation of pulmonary vasomotor tone in the fetus and neonate

Ngày tải lên : 20/12/2015, 04:12

... due to increased flow is offset by the decrease in shear stress due to increased vessel diameter Distinguishing the role of shear stress, or indeed the effects of increased synthesis of other endogenous ... modulators of vasomotor tone Of these, NO and prostacyclin play particularly important roles in maintaining adequate PBF during fetal development and in mediating the precipitous decrease in PVR ... treated in utero? Future studies must address these and other questions in order to gain a better understanding of the physiology and pathophysiology of pulmonary vasomotor tone in the fetus and...

6
280
0

The study on characteristics of the image and value of ultrasound, computed tomography in the diagnosis and follow up of hepatobiliary f

Ngày tải lên : 01/07/2016, 11:15

... been implemented in local health system and ability to find eggs of Fasciola ssp in the stool is very low New contributions of the thesis Combining US and CT images with eosinophil tests to build ... Serrano and colleagues conducted CT for patients with fascioliasis In 2007, Kabaalioğlu A and colleagues reported the results of sonographic and CT findings in 87 patients during the initial phase and ... Disadvantages of the research: Not any research had been published fascioliasis diagnostic score based on the combination of US and CT findings of hepatic lesions in fascioliasis with eosinophilia test in...

24
294
0

EXAMINATION OF THE MARKETING ACTIVITY OF HUNGARIAN SMEs WORKING IN THE DAIRY AND MEAT PROCESSING INDUSTRY

Ngày tải lên : 19/12/2016, 12:12

... operation of the “marketing department” Another suggestion is to make a written marketing plan with a well-defined budget The proposals include the definition of the role of marketing within these ... out on the basis of agreement of 44 statements appearing at the end of the questionnaire regarding the enterprise’s way of thinking and activity The results of research showed the following: different ... strategy making ability – can jointly result in the creation of marketing strategy in harmony with the enterprise aims and the ability of long term planning, which are the results of the process The...

37
308
0

Tài liệu recent trends in the law and policy of bioenergy production promotion and use docx

Ngày tải lên : 21/02/2014, 05:20

80
497
0

Tài liệu PRINCIPLES AND PRACTICES OF ORGANIC LETTUCE SEED PRODUCTION IN THE PACIFIC NORTHWEST potx

Ngày tải lên : 21/02/2014, 21:20

... lettuce is thinned within rows to the final spacing of 12 – 1 6in (30 – 40cm) Transplanted lettuce would be spaced at the final spacing of 12 – 1 6in (30 – 40cm) within row and 18 – 3 0in (46-76cm) ... fungus The symptoms of Sclerotinia rot are wilting of the lower leaves, followed by rotting of the base of the head Sclerotinia can infect a field through a number of mechanisms The first is via wind, ... contamination in the gathered seed The plants are harvested with the roots in order to Sclerotinia overwinters in the soil as sclerotia, which germinate when soil temperatures increase in the growing...

12
553
0