mechanisms of calcium regulation in sea urchin eggs and their activities during fertilization
Báo cáo y học: "Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cell" pdf
... or the signaling pathways that they control Finally, our understanding of how regulatory T cells develop and perform their function is beginning to coincide with our understanding of costimulatory ... molecule–ligand pairs With the original costimulatory ligand pairs of B7-1/B7-2 and CD28/CTLA-4 there is now a fairly detailed biochemical and cell biological understanding of their properties and their ... O’Garra A: In vitro generation of interleukin 10-producing regulatory CD4+ T cells is induced by immunosuppressive drugs and inhibited by T helper type (Th1)- and Th2-inducing cytokines J Exp...
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Undaria pinnatifida Habitat Loss in Relation to Sea Urchin Grazing and Water Flow Conditions, and Their Restoration Effort in Ogatsu Bay, Japan
... grazing pressure of sea urchin 80 70 60 50 40 2003 30 2004 20 10 0 10 20 30 40 50 Density of sea urchin (ind m-2) 70 50 60 U pinnatifida (Line 1) U pinnatifida (Line 2) Sea urchin (Line 1) Sea urchin ... habitats in the sea urchin - dominated barren grounds by the reduction of grazing pressure of sea urchins CONCLUSIONS U pinnatifida habitats in the inner areas of Ogatsu Bay, Japan, declined during ... appeared in Line The numbers of sea urchin were 212 and 365 ind per belt transect in 2003 and 2004, respectively, but both populations of sea urchin in Line were less than those in Line We also...
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Tài liệu Reading Our Lips: The History of Lipstick Regulation in Western Seats ... doc
... lack thereof Women’s lobbying in favor of food, drug, and cosmetics regulation continuously increased in terms of both numbers and intensity The coalition of women’s interest groups expanded from ... Goya introduced the first lip liner in the form of its “Thick and Thin” lipstick, a set of two tubes linked by a chain, with the “thick” tube containing lipstick and the “thin” tube containing ... have since grown increasingly detailed as well as increasingly accepted.353 Simultaneous to this fighting over delisting of colorants and listing of ingredient though, the FDA and the cosmetics industry,...
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Báo cáo khoa học: Casein phosphopeptide promotion of calcium uptake in HT-29 cells ) relationship between biological activity and supramolecular structure ppt
... than 10 min, including a 1–2 interval between the addition of Ca2+ and that of CPP In this period of time, cells maintained full viability As a control, [Ca2+]i concentrations after ionomycin treatment ... absorption of calcium by casein phosphopeptides in rachitis and normal chicks J Nutr 119, 2141–2148 25 Bronner F, Pansu D & Stein WD (1986) Analysis of intestinal calcium transport across the intestine ... Intestinal absorption of calcium in rats given diets containing casein or aminoacid mixture: the role of casein phosphopeptides Br J Nutr 49, 67–76 38 Sato R, Noguchi T & Naito H (1986) Casein...
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MECHANISMS OF AESTHETIC EXAPTATION IN ARTEFACT DESIGN: HOW A BEAUX-ARTS GARDEN EVOLVED INTO AN AVANT-GARDE ART PARK pptx
... new interdependencies created by the combination of different elements and it is rooted in a change in the capacity of seeing and perceiving relationships more than in an increased capacity in ... theories of change and innovation Then I turn to an illustration of the methods and the findings of the case study, which are analyzed and used to build a process model of cognition and exaptation in ... exchange of a naming opportunity on an area of the park and to be involved in the definition of the artistic enhancements Fund-raiser brokers had their target donors welldefined in mind On his...
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Báo cáo khoa học: Gene regulation by tetracyclines Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes Christian Berens and Wolfgang Hillen pptx
... the inducer-binding and dimerization domain is in dark gray, activation domains are black boxes, and the silencing domain is stippled The conformational change leading to the loss of DNA-binding ... cerevisiae [88] have lead to a profound understanding of how DNA binding, inducer binding and dimerization function in TetR This informa- Gene regulation by tetracyclines (Eur J Biochem 270) 3113 ... studies by allowing combination of the existing components instead of having to generate all cell and mouse lines, a costly and time-consuming process Ongoing improvement of the existing components...
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Báo cáo khoa học: On the mechanisms of glycolytic oscillations in yeast potx
... activating mode is the abundance of AMP and ADP, and scarcity of ATP (i.e the minimum of the ATP oscillation instead of the maximum), and the inhibitory mode is abundance of FBP and scarcity of G6P ... this understanding of the dynamic system to obtain an interpretation of the biochemical nature of the activating and inhibiting modes In essence, we this by mapping the measured phase and amplitude ... of G6P and F6P, and the inhibiting mode is high energy charge The activating and inhibiting feedback can be explained by the same reasoning as given for the interpretation in panels B and E;...
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Báo cáo hóa học: "Expression of 14-3-3 protein isoforms in mouse oocytes, eggs and ovarian follicular development" pdf
... also interest in understanding the role of 14-3-3 proteins in the regulation of oogenesis and the cell cycle during oocyte maturation and in early development In addition, 14-3-3 proteins, by their ... including regulation of the cell cycle, metabolism and protein trafficking We are particularly interested in the role of 14-3-3 in meiosis in mammalian eggs and the role 14-3-3 proteins may play in ... (using standard Western blotting procedures), each testing for one of the seven isoforms in protein extracts Oocytes and eggs were rinsed in MEM, counted, and transferred to Tris-buffered saline...
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Mechanisms of salt tolerance in halophytes pps
... salinity stress; with both a reduction in the total number of seeds germinating and a delay in the initiation of the germination process Seeds of many species, including Atriplex halimus and ... of sodium [77] This mechanism may be very important in Fig.9 The effect of changes in concentration of NaCl and KCl on stomatal opening in detached epidermis of Commelina communis, in light and ... rather than in vitro may occur due to increase in substrate concentration, and increase or decrease in levels of enzymes involved in intermediate metabolism The ability of halophytes to grow in highly...
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Báo cáo y học: " Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ" pot
... directly be involved in the induction of myelopoietic cytokines and/ or chemokines and whether IFN-γ may influence this process Materials and methods Antibodies and cytokines Recombinant mouse ... importance of STAT1 and IRF-1 in the inhibitory action of IFN-γ, the percentage of inhibition of the expression of GCP-2, RANKL and IL-6 mRNA induced by synergistic action of IL-17 and TNF-α was ... immunization by injecting 20 μg of CII in the left ears and vehicle in the right ears Bars in Figure 3d represent the percentages of swelling in the CII-challenged ears, normalized to the swelling of the...
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Báo cáo y học: "Quantifying the mechanisms of domain gain in animal proteins" doc
... domain gain in animals and there are also indications of the importance of adjacent gene joining [11] and NAHR [43] in the formation of chimeric genes in the Drosophila lineage Terminal gains of ... position of the domain insertion and the number of exons gained in the set of high-confidence domain gains and the set of medium-confidence domain gains (a) The distribution of characteristics of domains ... mechanisms that can add domains to the middle of proteins could be found in the larger set Figure Distribution of domain gain events according to the position of domain insertion and number of...
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báo cáo khoa học: " Whole-Organ analysis of calcium behaviour in the developing pistil of olive (Olea europaea L.) as a tool for the determination of key events in sexual plant " ppsx
... performed using material collected during the flowering season of 2010 and 2011 (N = 6) The mean and standard deviation values were calculated and plotted using the SigmaPlot software (Systat, Software, ... in vitro and in vivo conditions [22,41] Indeed, the presence of Ca2+ in the style has been reported in Petunia hybrida [18] and in tobacco [19] The implication of Ca2+ in pollen tube growth and ... be introduced into the examined cells, and this step is a prerequisite to measure intracellular Ca2+ ions by using microscopy imaging techniques To introduce this dye into intact pistils, we injected...
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Báo cáo y học: " Horizontal gene transfer and the evolution of transcriptional regulation in Escherichia col" ppt
... derived from known CRP binding sites in E coli to predict binding sites for CRP upstream of these operons and upstream of their xenologs in other γ-Proteobacteria (see Materials and methods, below) ... analyzed the history of each of the global regulators, and of a sample of each of the other types of regulators (see Figure and Materials and methods, below; for data on individual TFs, see Additional ... slowly than other regulators, both in terms of gene gain and gene loss and in their amino acid sequence Co-transfer of neighbor regulators with regulated genes In contrast to global regulators,...
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Báo cáo y học: " ModuleMiner - improved computational detection of cis-regulatory modules: are there different modes of gene regulation in embryonic development and adult tissues" pptx
... results in ten clusters with sizes ranging from 26 to 214 genes Large clusters were randomly divided in a training set of 50 genes, and a test set containing the remaining genes The performance of ... of ModuleMiner prompted us to apply the algorithm to gene sets obtained from clustering microarray data In nine out of ten microarray clusters, ModuleMiner succeeded in finding similar CRMs in ... binding sites for smooth muscle specific transcription regulation In contrast, the SMAD4, SP1, and ATF3 PWMs occur exactly once in 97.5% of the TRMs (SMAD4 and SP1 occur twice in 1.5% and 1% of...
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MECHANISMS OF BINDING DIVERSITY IN PROTEIN DISORDER: MOLECULAR RECOGNITION FEATURES MEDIATING PROTEIN INTERACTION NETWORKS
... 1.2 Intrinsic Protein Disorder in Protein-Protein Interactions Many proteins execute their biological functions through protein-protein interactions By binding to interacting partners, proteins ... other hand, three distinct binding profiles were identified in the collected many-to-one dataset: similar, intersecting and independent For the similar binding profile, the distinct MoRFs interact ... .xiv Chapter 1: Introduction 1.1 Intrinsic Protein Disorder and Protein Functions .1 1.2 Intrinsic Protein Disorder in Protein-Protein Interactions 1.3 Characterization of Molecular Recognition...
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MECHANISMS OF CYTOSKELETAL DYSREGULATION IN THE KIDNEY PROXIMAL TUBULE DURING ATP DEPLETION AND ISCHEMIA
... rich in proline, serine and threonine residues, and then finally a C-terminal SH3 domain The SH3 domain of cortactin binds with multiple partners, for example the proline-rich domain of dynamin-II ... Tyrosine phosphorylation level of dynamin-II decreases in LLC-PK1 cells upon ATP-depletion and Src kinase inhibition The SH-3 domain at the C-terminus of cortactin binds with proline-rich domain of ... N-WASP and WASP [65]; WIP (WASP-interacting protein) which is involved in filopodia formation [66] Figure Cortactin structural domains Fig The structural domains of cortactin and the interactions of...
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Medsoft, deciphering principles of transcription regulation in eukaryotic genomes
... domains 19 DNA-binding Domains In accord with the sequence and structure of DNA-binding domains, regulatory proteins are often grouped into class The goal function of the DNA-binding domain rules ... remodel the chromatin so that activators and the basal machinery can bind The mechanisms of remodeling contain changes in the structure of chromatin and in modification of histones that in some way ... focus of interest in the gene expression area Many classes of DNA-binding domains have been described in eukaryotes [41] Some DNA-binding proteins not fit into any of the defined class, whilst in...
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Experimentation, modeling and control of calcium dynamics in human vascular endothelial cells
... identifying the structure of the mechano-sensor in VECs membrane, finding signaling pathway given certain type of mechanical stimulus and investigating the interplay of gene expression and cell ... concentration of ATP on cell surface, in uencing calcium mobilization in an indirect fashion In the meanwhile, there were several other groups providing their results supporting Ando’s point of view ... biological/physiological and engineering perspectives Proficient skills in handling cells and chip In our case, we need to integrate cell culture, ATP release measurement and Ca2+ imaging into the one system The main...
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Structural investigations of redox regulation in ATFKBP13 4
... experiments to determine the interacting domains of the AtFKBP13 and the Rieske proteins A number of cDNA fragments encoding various domains of the AtFKBP13 or Rieske protein were fused in frame with ... with either the DNAbinding or activation domain of the Gal4 protein in the vectors Different combinations of these constructs were co transformed into yeast strain Y190 The interactions were studied ... Cys5 ,Cys106 and Cys111 thus opening up the structure at the N-terminus One of the most striking features of the reduced (inactive) form of the protein is the way in which the C-terminal extension...
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Structural investigations of redox regulation in ATFKBP13 3
... protein as described [Mould and Gray,1998] Import assays containing intact chloroplasts (0.5 mg chlorophyll ml-1), mM methionine, mM cysteine, and 10 mM MgATP in a final volume of 500 µl of import ... polypeptides fragments Main-chain tracing and building was performed using XtalView [McRee, 1999] The remainder of the structure (cis-prolines, poorly ordered loops and terminal residues for each ... smaller in subsequent runs after the introduction of information suggested by the program during the rebuilding stages This indicated more geometrically acceptable changes are incorporated and refinement...
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- give a critical analysis of the concept of self defence in public international law and international humanitarian law
- the role of capital market in nigeria economic growth and development
- evidence of oxidative stress in alzheimer disease brain and antioxidant therapy
- mechanisms of penicillin resistance in streptococcus pneumoniae targets gene transfer and mutations
- mechanisms of visceral sensitization in humans
- die‑off of indicator pathogens in sea water and fresh water
- cellular and molecular mechanisms of methotrexate resistance in melanoma
- mechanisms of momentum transport in viscous flow sintering
- mechanisms of reciprocal regulation of endothelin 1 and nitric oxide
- 2 mechanisms of brain injury in cardiac surgery
- on the structural mechanisms of functional states in neurons of the cerebral cortex
- general principles of self regulation in cortico subcortical correlations
- analysis of transcriptional regulation in bone cells
- behavioral mechanisms of immune alterations in depression
- mechanisms of physical protection in fine and coarse textured soils
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