... new interdependencies created by the combination of different elements and it is rooted in a change in the capacity of seeing and perceiving relationships more than in an increased capacity in ... a process of making connections among different problem domains (e.g combining alternatives generated in the domain of fund-raising with alternatives generated in the domain of design) This process ... regularities in the cognitive mechanisms producing them? Based on the findings of a longitudinal case study on the radical change of the aesthetic features of a complex artifact –e.g the design of a...
... understanding of the dynamic system to obtain an interpretation of the biochemical nature of the activating and inhibiting modes In essence, we this by mapping the measured phase and amplitude data of ... Annotations of the major components (B) Interpretation of the data discussed in the text In this panel, the phases of ATP and G6P have been ipped 180, indicating the relative phases of the minima of their ... the inhibiting mode is high energy charge The activating and inhibiting feedback can be explained by the same reasoning as given for the interpretation in panels B and E; the 2651 Mechanisms of...
... is indispensable for information intake and processing within the central nervous system Glutamate neurotransmission is crucial in information intake and information processing within the brain ... blood brain barrier (BBB) is seen early in neuroinflammation, and parallels the release of proinflammatory cytokines [26-28] Mechanisms for disruption of the BBB in neuroinflammation are incompletely ... ([Glu]ec in normal (IL)-1β, and ILSchematic in thefactor-α (TNF-α),) interleukinbraincytokines Figure (right)1 tumor necrosis presence of regulation of extracellular (left), and drawing of cellularthe...
... assurance of traffic safety - Norms of evaluating the friendly effect to environment - Norms of evaluating the uses of energy in public transport - Norms of evaluating the improvement of investment ... density in big cities, especially in Hanoi and Ho Chi Minh City, is more and more increasing, leading to the situation of increasing traffic congestion, decreasing average traffic speed, increasing ... failure of urban transportin the world in aspects of awareness, planning, development of public transport and intervention roles of Government (2) Evaluation on current situation of public transport...
... to increased salinity stress; with both a reduction in the total number of seeds germinating and a delay in the initiation of the germination process Seeds of many species, including Atriplex halimus ... development, one of the most sensitive periods in the life cycle of halophytes, to ensure survival of the developing seedlings [83] NaCl priming in melon seedlings grown in saline conditions increases ... rather than in vitro may occur due to increase in substrate concentration, and increase or decrease in levels of enzymes involved in intermediate metabolism The ability of halophytes to grow in highly...
... immunization by injecting 20 μg of CII in the left ears and vehicle in the right ears Bars in Figure 3d represent the percentages of swelling in the CII-challenged ears, normalized to the swelling of the ... of ELR+ CXC chemokines in RA synoviocytes, especially in the presence of TNF-α, highlighting its role in neutrophil recruitment into the joint [49] Furthermore, IL-17 induces the production of ... contributing to this protective effect of IFN-γ in CIA are inhibition of the CFA-induced myelopoiesis and osteoclastogenesis, inhibition of the production of GCP2 and thus neutrophil infiltration,...
... domain gain in animals and there are also indications of the importance of adjacent gene joining [11] and NAHR [43] in the formation of chimeric genes in the Drosophila lineage Terminal gains of ... domain has lost the introns present in the original sequence and the pre-SET domain has an intron containing repeat elements in a position not present in the original domain, suggesting it was inserted ... position of the domain insertion and the number of exons gained in the set of high-confidence domain gains and the set of medium-confidence domain gains (a) The distribution of characteristics of domains...
... 1.2 Intrinsic Protein Disorder in Protein-Protein Interactions Many proteins execute their biological functions through protein-protein interactions By binding to interacting partners, proteins ... thus leading to extremely complicated protein-protein interaction networks 1.7 Importance of MoRF Mechanismsin Hub Proteins Independent of their roles in hub protein interactions, intrinsically ... Modifications in One-to-Many Binding 56 3.2 Many-to-One Binding 59 3.2.1 Peptide-Protein Interactions and Protein-Protein Interactions .61 3.2.2 Binding Profiles: Independent...
... rich in proline, serine and threonine residues, and then finally a C-terminal SH3 domain The SH3 domain of cortactin binds with multiple partners, for example the proline-rich domain of dynamin-II ... C-terminus of dynamin is the PRD (proline-rich domain) which mediates the binding with multiple partners including cortactin Figure Dynamin structural domains Fig The structural domains of dynamin ... amino acid sequence of dynamin contains a GTP-binding domain [94], one of the major focuses of dynamin research has been its function in endocytosis as a GTPase by acting either like a pinching-force...
... Coefficients in the mode amplitude equations of velocity none Coefficients in the mode amplitude equations of contaminant none B The local width of the domain cp The specific heat of water c A contaminant ... loading as a point in ow source of contaminant and developed an optimal control model to determine the optimal pollutant loads at different in ux points along the course of a river in order to reduce ... costs In the study by Alvarez-Vazquez et al [29], the strategy consists of the injection of clean water from a reservoir at a nearby point into the river in order to dilute the contaminant in the...
... (a) the elements for sintering force shown in a geometry of twoparticle and sintering force acting on three particles model for (b) initial sintering stage (c) final sintering stage .89 ... neighboring grains thus results in the shrinkage of fine grains being consumed by coarse grains The existing understanding of the sintering and grain growth have been developed with the use of conventional ... using the nanosized powders, are of interest Chapter Introduction 1.3 Solid-State Sintering 1.3.1 Understanding in Solid-State Sintering Green parts require sintering before they can be used “Sintering...
... Effects of ENSO on rainfall in Central of Vietnam in the autumn, the role of moisture transport 4.4.1.1 Distribution of total rainfall in the autumn over Central of Vietnam Total rainfall in the ... event in 1997-1998 caused droughts in October and November in 1997 In contrast, the increase of moisture in the East Sea during the autumn is an element causing the increase of rainfall in the ... moisture transport and heavy rain in La Niña events in Vietnam 4.3.1 Effects of La Niña on heavy rains in Vietnam According to the calculations of the capability of occurring heavy rain under...
... driven flowin an inclined square cavity 152 Fig 2.7 Grid system utilized in the inclined square cavity (a coarse grid is shown here) 152 Fig 2.8 Streamlines at different Re numbers in the inclined ... transiently increasing fluid-phase endocytosis; and they are capable of producing intracellular actin and myosin filaments that are oriented in the flow direction Eskin et al (1984) investigated ... one of the most important nutrients for cells However, it is often the limiting nutrient because of the difficulty in bringing sufficient amounts of oxygen to the surface of the cells mainly...
... to investigate the swirling flow and oxygen transportin a stirred micro-bioreactor A numerical model was developed to investigate the flow field and mass transportin a micro-bioreactor in which ... Temperature and streamline contours for difference Ra 158 Figure 3.7 Schematic of a flowin a pipe 159 Figure 3.8 Velocity profiles of the pipe flow 159 Figure 3.9 Schematic offlowin a chamber with ... rotating 159 Figure 3.10 Streamline contours in the meridional plane in the cylindrical chamber with a bottom-wall rotating; H/R = 2.0 and Re as indicated 160 Figure 3.11 Schematic of a flow in...
... many proteins involved in apoptosis, including the expression profiles of proteins involved in the mitochondrial (bcl-2, bax, and bcl-x, etc.) and stress reaction-related pathways of apoptosis ... of protein changes for the experimental sample to control detected by using the Odyssey Infrared Imaging System (+) means an increase of signal intensity, and (-) means a decrease of signal intensity ... of protein changes for the experimental sample to control detected by using the Odyssey Infrared Imaging System (+) means an increase of signal intensity, and (-) means a decrease of signal intensity...
... the beginning of leaching, decreased after a peak, and then increased and decreased again This behavior indicates that the initial leaching is like Na+ leaching, and the surplus Ca2+ is drained ... observe the runoff rate of salts The four-electrode sensor consisted of four stainless steel rods inserted in parallel into an acrylic column with an inner diameter of 50 mm, outer diameter of 60 mm, ... study was to examine the change in hydraulic conductivity that occurs as a result of adding the gypsum, and to examine the transportof solutes in alkali soil reclamation The inner hydraulic conductivity...
... air gap with a minimum of cm The role of this layer is to prevent heat getting into the building in summer and take moisture out of the building In this ventilated gap the aluminum substructure ... one of the more affecting factors to increase the efficiency of the façade is the external air temperature The presence of ventilated façade in a building leads to a cooling effect in the skin of ... Miguel Mora Pérez M.Sc .in Industrial Engineering, Master in Energy Technology for Sustainable Development and Research Engineer in the Department of Hydraulic Engineering (Universidad Politécnica...
... discretization of the continuous rib The present investigation was therefore, taken up to determine the optimum width of a gap in the inclined rib to form discrete rib This study will help in determining ... the gap in the inclined rib releases the air partly belonging to the secondary flow and partly belonging to the main flow through the gap As a result of the presence of gap, the secondary flow along ... an inclined continuous rib is shown in Figure The flow upstream of the rib could not be visualized as the inclined portion of the rib has blocked this area However, the flow field downstream of...
... modeling of contaminant transportin a coupled fracture matrix system E-mail address: itsrajan2002@yahoo.co .in G Suresh Kumar is an Assistant Professor in the Department of Civil Engineering, Indian ... Canada, before joining at IIT-Madras His research interests include numerical modeling offlow and transport processes in a fractured formation He has published 10 research papers in International ... the mixing of radionuclides within the fractures significantly as against the mixing experienced in a coupled fracture- matrix system in the absence of colloidal transport Significant mixing prevailed...
... in inconsistent responses We found inconsistencies in 12.2% of the sample, indicating the difficulties in communicating the information about the mechanism of action To assess the influence of ... would consider using and would stop or continue using In addition, hypothetical choices were examined in terms of a non-specific "method of family planning" and not in terms of actual methods ... cross-sectional survey in a sample of women in reproductive age (18–49) from ten Primary Care Health Centres in various areas of Pamplona, Spain Women attend this kind of centre for obtaining primary care...