... symptoms and the three subdomains of functioning at baseline are illustrated in the path analytic diagrams presented in Figure At baseline, processing speed affected functioning mainly indirectly ... – instrumental, intrapsychic, and interpersonal, at baseline and following 24 weeks of antipsychotic drug treatment in patients with schizophrenia We used a path analytic approach to evaluate ... directly or indirectly affect functioning; in the latter case, via changes in symptoms We found that only processing speed was significantly associated with functioning at both baseline andat 24 weeks...
... stage III as defined by the creatinine criteria (ie rise in serum creatinine to ≥ 354 μmol/L or rise in serum creatinine by >300% from baseline within 48 hours) who were not treated with RRT We also ... The remaining 583 patients had RRT without a 300% change in creatinine or a creatinine of 354 μmol/L or more (as per AKI stage III classification) or without being oliguric Multivariate logistic ... were associated with a worse outcome in AKI patients [11,22,23] Bagshaw and colleagues analysed the data of 1260 ICU patients treated with RRT and found that the median serum creatinine at time...
... thoughtful.’ ‘You sit at home,’ said the cat, in your dark-grey fur coat and long tail, and are filled with fancies, that’s because you not go out in the daytime.’ During the cat’s absence the mouse ... the name in my life, I’ll wager anything it is not in the calendar!’ The cat’s mouth soon began to water for some more licking ‘All good things go in threes,’ said she, ‘I am asked to stand godmother ... said she, and was quite satisfied with her day’s work When she went home the mouse inquired: And what was the child christened?’ ‘Half-done,’ answered the cat ‘Half-done! What are you saying? I...
... gland (Laptikhovsky and Nigmatullin, 1987) Juvenile phase and physiological maturation Physiological maturity, functional maturation and maturity Initially the embryonic gonad in octopus is paired ... it seems inappropriate to include functional maturation and maturity in a single maturity stage (as in Zuev et al., 1985) The processes of formation of sexual products are different in their ... by one without accumulating them in the coelom Stage IV indicates the presence of several ripe oocytes in the coelom and stage V when they pass into the oviduct during spanwing With maturity...
... resulting from the use of chlorine dioxide Chlorite and chlorate formation increase (in a ratio of 7:3) with increasing concentration of chlorine dioxide and increased treatment time Chlorine dioxide ... that are more heavily contaminated (SCVPH, 2003) It must be emphasised that, in general, decontamination treatments are able to reduce the contamination level but not completely eliminate pathogens ... the skin, even untrapped in inaccessible sites Spray rinsing at several points along the processing line is an effective means of minimising contamination but is not so effective especially in exposed...
... studies examining natriuretic peptide levels and/ or inflammatory markers during inotrope administration with inconsistent results [8-11] Adding complexity to this picture is data indicating that the ... patients care continued to be at the discretion of the attending physician, including inotrope administration and dosing It is well recognized that heart failure leads to increased circulating ... participated in design, coordination, data interpretation, performed the statistical analysis, and drafted the manuscript RH participated in design and coordination of the study, data collection, and...
... found that treatment with vinorelbine, mitoxantrone and estramustine yielded a response rate suggesting clinical activity in men with CRPC, and was well tolerated The combination of CRA/IFN and paclitaxel, ... combined navelbine and mitoxantrone, supporting the testing of combination therapy with estramustine, mitoxantrone, and vinorelbine in patients with CRPC One study demonstrated a potential clinical benefit ... al.: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant...
... than in healthy controls (83.9 μM on average; data not shown) at any timepoint, in line with previous data on altered Trp catabolism in cancer patients [24] In order to more accurately substantiate ... stimulating factor treatment of Crohn’s disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells Clin Exp ... filgrastim in the human setting [34] In this study, daily treatment with G-CSF for weeks was correlated with an increase of IL-10-secreting type Treg cells in the peripheral blood andwith the accumulation...
... and AZ formulated the rehabilitation paradigm and training protocol AM and TH were the main contributors in the acquisition of the data, analysis and interpretation of the clinical findings and ... target zones (defined by a pattern of trunk inclination and local accelerations) which were adaptively estimated during a short initial calibration phase in the beginning of each training session ... categories of posture and balance with increasing difficulty and complexity These included: (1) static posture control-achieving better upright position while sitting andin standing (improving...
... the analysis and interpretation of data, drafted and revised this article Suzukamo Y assumed the coordination and design of this study, training interviewers and interpretation of data Nakamura ... severity and patient-reported severity However, in many cases patients' and physicians' ratings of severity differed greatly The patients' ratings were dichotomized between severity scores of 19 and ... having clinically mild disease, those given non-topical medications (including non-topical antibiotics) were categorized as having clinically moderate disease, and those in whom permanent scarring...
... population) The finding that one point increase in the Δ PCS score was associated with an approximately 0.17 point decrease in the Δ HADS scores can be regarded as clinically significant, since ... were being treated for anxiety and depression was quite stable during the study We can only speculate on the reasons for this finding The data showed that the patients who were being treated for ... resulting from the procedure, patients are encouraged to eat a high protein diet and to take prescribed daily doses of vitamins and minerals Demographic characteristics and clinical data Data were...
... explained within this context Despite the fact that clinical experience accepts high comorbidity in pulmonary patients, studies assessing and comparing anxiety and depression levels among patients ... patients with moderate failure andin 50% in patients with severe obstructive pulmonary disease [15,16] Anxiety and depression are very prevalent even in patients with moderate COPD (categorized ... Competing interests The authors declare that they have no competing interests References 10 Wells KB, Golding J, Burnan MA: Psychiatric disorder in a sample of the general population withand without...
... analyzing different chemotherapeutic combinations, substances such as cisplatinum might inactivate or attenuate MGMT-status thus influencing the clinical outcome when combined with alkylating chemotherapies ... evaluated the impact of MGMT-promother methylation as well as IDH1-mutational status on outcome in 160 patients with GBM treated with radiation and temozolomide IDH1 mutations occur in approximately ... and correlated results with outcome Materials and Methods Patient population Between 1999 and 2007, 160 consecutive patients with primary, histologically confirmed GBM were treated with radiation...
... clinical situation, we investigated the effect of fractionated radiation Compared withand 7.5 Gy as a single dose, and × 2.5 Gy resulted in considerably less jejunal damage (Table 1), indicating ... or in combination with radiotherapy When combined, 5-FU was injected immediately followed by the administration of oxaliplatin one hour prior to radiotherapy Control animals were given saline injection ... equal intestinal damage These doses were then combined with radiation in the next step Single radiation fractions, ranging from - 10 Gy, were given alone, or in combination with equitoxic single doses...
... cyclo-oxygenase-2 (COX-2) inhibitor for the treatment of OA and acute pain In two 13week, international, multicentre, double-blind studies in patients with OA of the knee, it was compared with celecoxib ... pain, patient's global assessment of disease activity, and functional impairment We present data on patient satisfaction according to PASS during andat the end of the study period and on patient ... PASS, Patient Acceptable Symptom State; SD, standard deviation was exceeded and subsequently maintained during consecutive visits until week 13 (inclusive) Missing data were not imputed Only patients...
... Unexpected findings were the significantly lower serum total protein and α1-globulin, α2-globulin, β-globulin, γ-globulin, and IgG levels in those with silicone implants compared with those without ... years) in those without silicone implants (P = 0.06) The women were also matched for diagnosis (64 patients with various inflammatory CTD, 10 patients with noninflammatory CTD (FMS), and 14 patients ... that FMS patients may differ from inflammatory CTD in the risk of paraproteinemia, we analyzed the women in each group without FMS and found that excluding them does not alter the primary findings...
... demonstrated that activation of cannabinoid receptors attenuates inflammation and nociceptive processing in models of cutaneous and joint inflammation [1014] The cannabis-based medicine Sativex ... treatment of pain and inflammation associated with these conditions Competing interests FAAH, and MAPK assays and associated statistical analyses LL performed CB1/CB2 Western blotting and statistical ... endocannabinoid system, including endocannabinoids, entourage compounds, CB1 and CB2 receptors, and FAAH, in the knee synovia of patients with end-stage OA and RA Materials and methods Patient information...
... antibody-inducing cytokine APRIL in the CNS of NPSLE patients compared with SLE patients without CNS involvement Elevated levels of IL-6 in CSF have been reported in NPSLE patients [40] and could ... in serum of SLE patients, (e) IL-6 and APRIL in CSF of SLE patients, and (f) IL-6 and BAFF in CSF of SLE patients APRIL, a proliferation-inducing ligand; BAFF, B-cell activating factor of tumour ... lupus erythematosus (SLE) patients Cerebrospinal fluid levels of (a) APRIL and (b) levels in cerebrospinal fluid of systemic lupus erythematosus (SLE) patients BAFF in SLE patients andin healthy...
... declare that they have no competing interests Authors' contributions JB developed the technique and wrote the manuscript; COP participated in the surgeries andin the clinical follow-up of patients ... approach, using the upper deltopectoral access, a tunnel is prepared, going under the dm, more laterally and distally, crossing above the humerus From the other incision, in line with the respected ... unto the remaining dm with the arm positioned in 90° abduction and 20° flexion This fixation is realized by several Maxon 2/0 sutures passed behind the rim suture on the tmm, so that a tight connection...
... didn’t find any correlation between Lp(a) levels and inflammatory status in our patients After performing survival analysis we found only slightly higher AF recurrence rate in group of patients with ... this article as: Naji and Sabovic: Lipoprotein(a) and inflammation in patients with atrial fibrillation after electrical cardioversion Journal of Negative Results in BioMedicine 2011 10:15 Submit ... coagulation parameters and clinical events, what could give further useful information about the role of Lp(a) in patients with AF We also weren’t able to prove the association between Lp(a) and inflammation,...