... (Invitrogen), and the isolation of RNA followed the manufacture’s protocol The synthesis of first-strand cDNA was performed using the Superscript preamplification system (Invitrogen) Either lg of total ... characteristic of 7-DHP (Fig 5) The H-NMR spectrum ofthe biotransformation product is in agreement with that ofthe chemically synthesized standard (Fig 5) and with data from the literature [41] Thus, the ... product of 7-DHC transformation (C) Differing from these reaction products were the parameters forthe 7-DHC; the retention time for its ion with m/z 385.3 and UV spectra are shown in the inset...
... accordance with the provisions ofthisConvention Article 24 Forthe purposes ofthis Part ofthe Convention, an offer, declaration of acceptance or any other indication of intention "reaches" the addressee ... Interpretation oftheConvention D Interpretation ofthe contract; usages E Form ofthe contract Part Two Formation ofthe contract Part Three Sale of goods A Obligations ofthe seller B Obligations ofthe ... paragraph for any lack of conformity ofthe goods if at the time ofthe conclusion ofthe contract the buyer knew or could not have been unaware of such lack of conformity Article 36 (1) The seller...
... Assemblage ofthe clones yield the full-length cDNA sequences of at least two distinct LDH-A isoforms, which differ substantially in the coding sequence and length ofthe 3¢-UTR Therefore, isoform-specific ... acclimation Therefore, we think that the described mechanism maintains either (a) the kinetic ⁄ thermodynamic properties ofthis metabolic node by ‘dilution’ ofthe major mRNA with the minor one; ... considered in the context ofthe relevance forthe performance of metabolic networks, because the theory of metabolic control analysis states that enzyme properties (concentrations, kinetics and thermodynamics)...
... To address the question of whether hypoxia influences the promoter activity ofthe human HO-1 or HO-2 gene, we performed transient expression assays Prior to the functional analysis ofthe HO-2 ... Effects of hypoxia on HO-1 and HO-2 expression in human cell lines We initially analyzed the effects of hypoxia on theexpressionof HO-1 and HO-2 in human cell lines of Reduced expressionof heme ... in the mouse liver after days of normobaric hypoxia (10% oxygen) and returned to the basal level after 14 days of hypoxia [26] It is therefore of significance to study the regulation of HO-2 expression...
... the Online Distributed Proofreading Team at http://www.pgdp.net (The original copy ofthis book was generously made available for scanning by the Department of Mathematics at the University of ... Ouvrage transformation z = THẫORIE DES FONCTIONS ELLIPTIQUES LIVRE PREMIER LES FONCTIONS ALGẫBRIQUES CHAPITRE PREMIER DẫFINITIONS On appelle quantitộ imaginaire une expression de la forme x + y ... Ouvrage a ộtộ fait Paris, et toutes les formalitộs prescrites par les Traitộs sont remplies dans les divers ẫtats avec lesquels la France a conclu des conventions littộraires Tout exemplaire...
... reference ofthe rules oftheConvention into the contract In this case, the rules oftheConvention may not override the mandatory rules ofthe otherwise applicable law Contracts governed by theConvention ... consists of articles 89-101 The Structure oftheConventionThe following summarizes the structure ofthe Convention: The text oftheConvention is introduced by a Preamble2 and concludes with an Authentic ... and Summary Records ofthe Plenary Meetings and ofthe Meetings ofthe Main Committee, 1981, 15 For an analysis ofthe issue of exclusion ofthe Convention, see the Digest for article 35 See...
... height of Snowdon, the distance ofthe moon, and the weight ofthe sun We have no desire to deceive ourselves upon any of these points, and therefore we have no superstitious shrinking from the ... tape forms a hinge You can lay one card flat and stand the other edgeways upright, and lace patterns between them from one to the other The use ofthis part ofthe method is to provide girls in the ... three answers ofthis kind:— x equals half of y; y equals twice x; z equals x multiplied by y The value of each depends on the value ofthe others When we get into a predicament ofthis kind, three...
... honor, honesty and fair dealing ofthe Agency We court the fullest and freest investigation, either by patients themselves or any friends of theirs in this city, either of whom we shall be happy to ... mankind, like any other power or appetite—to be enjoyed in reasonable moderation and forthepurposeof insuring a continuance of our species by the birth of offspring Many men abuse this power—abuse ... Injury to the Urine Canal from the rough use of sounds, bougies, catheters, &c., &c Any one or all of these, by extending the inflammation backward to the seminal ducts and neck ofthe bladder,...
... consequence ofthe strange happening ofthe serpent landing from the ship the end ofthe island on which the Temple of Æsculapius stood was shaped into the form ofthe bow of a ship, and the serpent of ... at the present time the visitor may see this ancient work in the Roman Forum, and trace its course to the Tiber In the Forum, too, to the left ofthe Temple of Castor, is the sacred district of ... Roman Medicine at the end ofthe Republic and the Beginning ofthe Empire Asclepiades of Prusa Themison of Laodicea Methodism Wounds of Julius Cæsar Systems of Philosophy State ofthe country Roman...
... others forthe prosecution of my studies during the remainder ofthe college course I hardly know now whether to be glad or sorry forthis deprivation But for this, I might have been a man of ... emancipation was theoretically the best plan It was forced upon us by the exigencies ofthe war And, independently of that, such was the infatuation ofthe Southern mind on the subject that there seemed ... dedicated, under the name ofthe Church ofthe Messiah The burning of our sanctuary had [80] proved to be our upbuilding; the position ofthe Stuyvesant Institute on Broadway, and the plan of free seats,...
... reproductive organs at puberty The female generative organs The function ofthe reproductive organs The age of puberty in the female The function ofthe ovary The function ofthe womb—Why menstruation ... twenty-eight days The male or papa egg The function ofthe spermatozoa—"Tell the whole story"—"How these spermatozoa get there" The union ofthe species—"How can a baby live in there for such a long ... cord—Treatment after the cord falls off—A pouting navel —Bathing baby—Clothing the baby— Baby's night clothes—Care ofthe eyes —Care ofthe mouth and first teeth— Care ofthe skin—Care ofthe genital...
... during the cruise, and the preparation of his own journal ofthe voyage for publication The strict scientific results ofthe trip were described in the 'Zoology ofthe Voyage ofthe "Beagle,"' the ... reptiles; the feet of lizards, the hoofs of horses, the hands of man, the wings ofthe bat, the pinions of birds, all arise from the same fundamental shapeless bud, in the same spot of an almost ... with the interpretation ofthe Egyptian hieroglyphics, and ofthe cuneiform inscriptions; with the undulatory theory of light, with the mechanical equivalent of heat, with the doctrine of the...
... did not live for many years Another was Mr Dawes, afterwards Dean of Hereford, and famous for his success in the education ofthe poor These men and others ofthe same standing, together with Henslow, ... 1831-1844 165 X. The Growth ofthe Origin of Species: 1843-1858 173 XI. The Writing ofthe Origin of Species, June 1858, to November 1859 185 Chapter VIII XII. The Publication ofthe Origin of Species, ... follows my father's career from interest in the man, and to the naturalist who desires to know something ofthis turning point in the history of Biology This part ofthe story has therefore been...
... control ofthe three famous Worrell sisters, who tacked their name to it Shortly after the New Year of 1869 they produced the extravaganza "The Field ofthe Cloth of Gold," in which two of them, Sophie ... Texas The reason forthe expedition was this: In Memphis business was so bad that the manager ofthe theater there advised Gustave to send the company through Texas, where, he assured them, there ... Wallack forthe first time Wallack was then the enthroned theatrical king and one ofthe most inaccessible of men Frohman finally contrived to see him and made the proposition forthe release of Tearle...
... in the nominative singular The stem without the “soft sign” (in the transformed spelling) would be a short entry on the pattern ofthe entries for “false stems”, while the stem with the “soft ... transformation ofthe form (6) until we are perfectly certain that the information thus lost is of no further use to us Another possibility which suggests itself is that of increasing the number of ... available forthe treatment of “false stems” in the dictionary it is possible to enter the stem *БОЛЬШ which results from the splitting off ofthe affix *ОЬ as one among a number of “false stems” in the...
... from the tripod or other means of getting over the fire Sometimes the bough of a tree high out ofthe reach ofthe flames will Sometimes a stick or oar thrust into the bank or in a crevice ofthe ... one inside the other The big lid then fits on the outer one and the two other lids have to be carried separately The Five-Foot Sausage You hang these camp-kettles over the fire by their bucket ... for him to compare the opposing views ofthe specialists, to reveal one in the light thrown by the other, to help into existence the new truth waiting to be born ofthe meeting of opposites Specialisation...
... relative to the other For comparison, the corresponding angle found for (nonactivated) KlPDC is 36° The main difference between KlPDC and the activated form of ScPDC is the flexibility ofthe loop ... arrangement at the active site enforces the so-called V-conformation of ThDP [17] This relative orientation ofthe pyrimidine ring and the thiazolium ring is one ofthe three conformations that ... binding ofthe regulatory substrate(s) in the cleft between the R and PP domains The bound activator may then enhance the rigidity ofthe enzyme molecule and drive the disorder–order transition of the...
... on the basis ofthe P value of 0.005 (ii) What is the probability of obtaining a correlation coefficient so far from zero for at least ofthe cancer cell types in the panel if the null hypothesis ... mechanisms of action based on their activity patterns across the 60 cell lines b, Cluster tree ofthe 118 drugs based on the correlation of their activity patterns with expression patterns ofthe genes ... tested, the number of missing values and the number of cell lines for which the GI50 value fell within the range of concentrations tested The smaller set of 118 included so-called “mechanism of action”...
... used for PCR amplification a + c for amplification ofthe larger IA transcript; b + c for amplification ofthe shorter IB transcript (B) PCR amplification ofthe two specific transcripts and ofthe ... identifies forthe first time, the presence of alternative promoter usage forthe MGP gene and provides clear evidence for differential expressionofthis gene during the very early stages of embryonic ... is reinforced by the fact that the pattern of IB amplification obtained follows roughly that observed from this stage on forthe larger IA transcript, although stage-specific expressionof IB in...
... In this way, we motivate an intermediate form of representation that represents a ‘context-free’ semantics oftheexpressionThe role ofthe recognition process is then to compute as much ofthe ... as violating the strong separation; rather, we distinguish the two steps ofthe process in terms ofthe extent to which they make use of contextual information in computing values Then, recognition ... semantic content of a temporal expression as can be determined on the basis oftheexpression itself, producing an intermediate partial representation ofthe semantics The role ofthe interpretation...