... con-
sistent pattern of the effect of smoking on risk of can-
cer deaths.
TABLE 1. Characteristicsof cases and two control groups:
Population-based case- controlstudyof smoking on risk of
cancer deaths ...
principles of a population-based case- controlstudy to
assess the validation of the novel control selection
design by comparing the consistency between the
new design and a routine control selection ... 152,579
controls (103,248 in control group 1; 49,331 in control
group 2) in our study. The basic characteristicsof the
cases and controls, and relative risk of smok-
ing-related cancer deaths...
...
cause of death; 80% ofcontrol subjects who were current smokers
of one or more packs per day died of a smoking-related cause
compared with 60% ofcontrol subjects who never smoked.
This study ... exposures.
Study design
A nested casecontrolstudyof lung cancer and DE in a cohort of
12 315 workers in eight non-metal mining facilities included 198
lung cancer deaths and 562 control subjects. ... lung cancer. Of the 217 eligible
case subjects identified, we interviewed 213 (98.1%) of their next
of kin.
Control Subject Selection for the Nested CaseControl
Study
Based on incidence density...
... 1 of 8
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Journal of Translational Medicine
Open Access
Research
A MIF haplotype is associated with the outcome of patients with
severe sepsis: a casecontrol ... LG: The SOFA (Sepsis-related Organ
Failure Assessment) score to describe organ dysfunction/
failure. On behalf of the Working Group on Sepsis-Related
Problems of the European Society of Intensive ... comparable
to both control groups. However, the genotype and allele frequencies of both polymorphisms were
associated significantly with the outcome of severe sepsis. The highest risk of dying from...
... Prognostic impact of clinical course-
specific mRNA expression profiles in the serum of perioperative
patients with esophageal cancer in the ICU: a casecontrol study.
Journal of Translational ... line refer to IL-6 mRNA, IL-6,
mean of normal IL-6 level in plasma, and predictive cut-off level of IL-6 mRNA, respectively. (c) SPSS software analysis of the AUC of the ROC
curve was 0.809 and 0.453 ... Journal of Translational Medicine 2010, 8:103
http://www.translational-medicine.com/content/8/1/103
Page 8 of 11
Recently, the use of gene-expression profiling on a
transcriptome level of peripheral...
... effectively monitored our working population. 12.9% of the 148 cases, and 3.2% of
the 220 controls had a positive QFT result. Another 14.8% of cases and 4.5% of controls had
conditionally positive QFT results. ... direct part of the study,
we noted that a subset of the subject cases (35) have had
recent TBST's (within the last 3 years) as part of their
ongoing medical evaluations. Only 4 of the cases had ... (34.0%) of the total 368 firefighters,
and were equally distributed among cases and controls.
For all positive TBST cases, 47 (31.8%) of 148 were posi-
tive for MA, while 78 (35.5%) of 220 positive...
... study design, performed the statistical
analysis and drafted the manuscript, UB participated in
the studydesign and and helped to draft the manuscript,
NA participated in the designof the study ... by cases
would lead to an overestimation of risks. Otherwise, a
non-differential overestimation of physical workload (in
both cases and control subjects) would lead to an under-
estimation of ... and a non-differential approach to
cases and controls. Participants were not informed of the
specific aims of the study. They were asked to participate
in a study concerning the theme 'occupation...
... number of follicles, whereas it is not
expression of PCOS endocrine impairment.
In this study, reproducibility of the measurements of
stromal volume was very close to that of ovarian volume
and of ... distance from the leading edge of
the second echogenic line of the far walls of the distal
segment of the common carotid artery, the carotid
bifurcation, and the initial tract of internal carotid artery
on ... and dou-
bling of cross-sectional ovarian area, observed by ultra-
sound, has been shown to be expression of a marked
increase (33%) of cortical portion, and of a five-fold
increase of medullar...
... KF designed and supervised execution of the study, interpreted
the data and drafted and revised the manuscript. JO, HH and MP supervised
execution of the study and revised the manuscript. MAG designed ... disadvantage: a case control
study on health-related quality of life in children with sickle cell
disease. Health and Quality of Life Outcomes 2010 8:121.
Hijmans et al. Health and Quality of Life Outcomes ... and Quality of Life Outcomes 2010, 8:121
http://www.hqlo.com/content/8/1/121
Page 6 of 8
RESEARC H Open Access
Double disadvantage: a casecontrolstudy on
health-related quality of life in children...
... than in the cases (cases 14 (13.5%) and controls 77
(27.1%); p = 0.005). Use of selective COX-2 inhibitors was
comparable (cases 17 (16.4%) and controls 50 (17.6%); p =
0.77). Use of the preferential ... admission:
standard care Number of days Cost manual of Oostenbrink 337.00
Intensive care Number of days Cost manual of Oostenbrink 1,684.00
Emergency department Number of visits Cost manual of Oostenbrink 139.00
Ambulance ... transportation:
Emergency Number of transports Cost manual of Oostenbrink 443.00
Regular Number of transports Cost manual of Oostenbrink 212.00
Blood products:
Packed cells Number of units Cost manual of Oostenbrink...
... treated.
2. Methods
2.1. Type of the Study
This is a qua si-experimental research based on one
study group and one control group and it focuses on
the studyof the i mpact of systematic preoperative
instruction ... found that anxiety was experi-
enced at a rate of 80% and the fear of not being able to
get rid of cancer and the fear of impairment of the qual-
ity of life were p articularly effective on anxiety. ... some characteristicsof the participant and
anxiety scores of patients.
3. Results
The researchers divided the sample groups into one
study group and one control group, each consisting of
60...
... compare the characteristicsof patients
prescribed celecoxib and rofecoxib, which are the two
COX-2 inhibitors marketed in Canada at the time of the
study.
Methods
Design
A casecontrol analysis ... the interpretation of the study results. SP
assisted in the review of the literature and determined the
relevance of the study. SZ conceived the study and partic-
ipated in its design. All authors ... compared. The study population
consisted of a random sample of members of the Quebec drug
plan (age 18 years or older) who received at least one
dispensation of celecoxib (n = 42,422; cases), rofecoxib...
... collected
systematically and included age at onset of psoriasis and PsA,
and disease pattern. The control individuals (controls) were of
similar ethnicity to the patients (cases). Controls for the New-
foundland ... al.
Page 2 of 3
(page number not for citation purposes)
Materials and methods
This study was approved by the local ethics committee of the
Memorial University of Newfoundland and University of
Toronto. ... participated in study
design, and drafted the initial manuscript. LP assisted in gen-
otyping some of the control individuals. SH aided in recruit-
ment and clinical phenotyping of PsA patients....
... (10.8%) of the healthy controls
included in the present study. Three of these resulted in amino
acid substitutions. Nine (8.8%) of the RA patients from the
present study exhibited five of these ... result of this study, the fre-
quency of uncommon PADI4 variants as identified earlier [8]
was apparently not different quantitatively or qualitatively
between patients and controls.
Of note, ... (Berlin, Germany). The designations of the
PADI4 haplotypes are in accordance with those of Suzuki and
colleagues [7]. The positions of novel exonic or intronic PADI4
variants were designated relative...
... historical control study, with controls
being active RA patients followed before the advent of TNF-α
blocker therapy and who were treated with methotrexate
alone. Such a historical control group is of ... Cary,
NC, USA) software.
Results
Control and infliximab group characteristics at baseline
Demographic, clinical, biological and BMD characteristics of
the 189 RA patients enrolled in the study are ... 1 year of infliximab treatment
[10]. However, in none of these studies was a control group
included, preventing a true estimation of the effect of anti-TNF-
a treatment on bone. In this study, ...
... [4].
Several limitations of this study deserve comment. Because of
strict inclusion and exclusion criteria, the accrual of patients
with RA was below the intended number of subjects planned.
Consequently, ... Institutes of Health (NIH), and all participants pro-
vided written informed consent.
Study design
Study participants were admitted to the Clinical Research
Center on the evening of day 1 to ... Blackman et al.
Page 4 of 9
(page number not for citation purposes)
Table 1
Characteristics of patients with rheumatoid arthritis
Variables Rheumatoid arthritis (n = 7) Controls (n = 10)
Age (years)...