bioinformatic methods for finding differentially expressed genes in cdna libraries applied to the identification of tumour vascular targets

Báo cáo y học: "A non-parametric approach for identifying differentially expressed genes in factorial microarray experiments" potx

Ngày tải lên : 14/08/2014, 14:21

... contributions of the highly significant genes in ANOVA on the top two axes in CA The 601 genes in Figure 3b explain 36.39% of the total variance in the first axis and 16.05% of that in the second axis The ... 220 genes in Figure 3c contribute to 17.02% of the variance in the first axis, 25.12% of that in the second axis and the 56 genes in Figure 3d account for only 1.91% of the total variance in the ... contribution of the i-th gene to the l-th axis The sum of acil for a group of selected genes stands for the proportion of the total variance explained by these particular genes If all the n genes are...

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Báo cáo y học: " A tool for comparing different statistical methods on identifying differentially expressed genes" potx

Ngày tải lên : 14/08/2014, 14:21

... being the total number of genes identified by SAM as having FDR less than α and K m ,α ,h being the total number of genes out of the top K α genes for method m lying outside of the contour of ... points at the beginning and the end of the stationary phase The data obtained from the Affymetrix software MAS 4.0 were transferred to the Gecko software [10] with minor modification The marginally ... profile - with up to 1/6 of the genes of the genome having different expression level – and allow for detecting profound changes in the galactose (comprising the GCY1 co regulated gene) biosynthesis...

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SCREENING FOR DIFFERENTIALLY EXPRESSED GENES IN DENGUE INFECTION UNDER ANTIBODY DEPENDENT ENHANCEMENT CONDITIONS

Ngày tải lên : 13/10/2015, 16:41

... enhancing infection Usually the antibody used is of IgG subclass Relying on the high affinity binding of the Fcγ portion of the antibody to the FcγR on the host cell, interaction of the virus and the ... hypothesis of ADE being the underlying mechanism for DHF Therefore, it was speculated that local autocrine of IL-10 early in the infection contributes to the peak viraemia The elevation of TNFα ... with the host FcγR might result in FcγR signalling within the host cell Both FcγR signalling together with the enhanced uptake of the virus could be the contributing factors to an overall increase...

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Báo cáo sinh học: "A weighted average difference method for detecting differentially expressed genes from microarray data" ppt

Ngày tải lên : 12/08/2014, 17:20

... advantageous result for the t-statistic-based methods since those methods were used in the original analysis for 15 of the 21 datasets Nevertheless, the best performing methods across the 36 experimental ... datasets including the 21 datasets seem to be independent of the originally analyzed methods, by virtue of WAD's high performance Also, the overall performances of eight methods for the two artificial ... bias regarding the datasets Therefore, we think the number of experimental datasets interrogated is also very important for evaluating the practical advantages of the existing methods A profound...

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Báo cáo y học: "Improving identification of differentially expressed genes in microarray studies using information from public databases" pptx

Ngày tải lên : 14/08/2014, 14:21

... promising (Figure 3) As before, our incidence of the top 50 genes in the top 10 listed, top 50 listed and top 100 listed are improved The voting method returns 88% more of the top 50 genes than the ... 75% of the value of the lower rank (nearer the top of the list) with 25% of the value of the higher rank A final score was obtained by combining the results from each method in this way, and the ... important to work with the given data in an optimal manner to extract as much information as possible In the context of finding differentially expressed genes, the null hypothesis for each gene...

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Báo cáo y học: "Identification of ciliated sensory neuron-expressed genes in Caenorhabditis elegans using targeted pull-down of poly(A) tails" ppsx

Ngày tải lên : 14/08/2014, 14:21

... Profiling of genes that are expressed in sensory neurons might therefore provide insights into the genes required for the specific functions of neurons To identify sensory neuron -expressed genes, ... those expressed in cholinergic neurons The gene set 'Muscles' was genes expressed in some muscles, but not in neurons or the intestine, while 'Intestine' was genes expressed in the intestine, ... contains the legends to the above three tables The primers tothe sensory the intestine,and results of the microarray experiments Genes listing additional threefor Click here datathethose of the...

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$Support to the identification of potential risks for the environment and human health arising from hydrocarbons operations involving hydraulic fracturing in Europe doc$

Support to the identification of potential risks for the environment and human health arising from hydrocarbons operations involving hydraulic fracturing in Europe doc

Ngày tải lên : 23/03/2014, 00:20

... monitoring and inspection Emissions to air, especially during drilling and fracturing, and releases to water during fracturing There may be inadequate measures for the monitoring and control of ... Within the scope of this study, hydraulic fracturing is to be understood as the cycle of operations from the upstream acquisition of water, to chemical mixing of the fracturing fluid, injection of ... with the depth and size of the hole depending on the ground conditions A vertical pipe is set into the hole and grouted into place The second drilling stage is to drill the remainder of the vertical...

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Báo cáo y học: "Statistical methods for detecting and comparing periodic data and their application to the nycthemeral rhythm of bodily harm: A population based study" ppsx

Ngày tải lên : 10/08/2014, 09:20

... and d7, the other on d1 to d5, see Figure for a plot of these two rhythms Now the “whiteness“ of the residuals of the fit of d1 to d5 is tested Figure shows a quantile-quantile-plot of the residuals ... or the choice of the number of samples, when no a priori knowledge of the inherent periods of the data is available To derive a more robust version of the statistical test use the rank of the ... supported by the Interdisciplinary Center of Clinical Research (IZKF) at the University hospital of the University of Erlangen-Nuremberg The authors wish to thank Joanne Eysell for proofreading the manuscript...

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báo cáo khoa học: " Training community resource center and clinic personnel to prompt patients in listing questions for doctors: Follow-up interviews about barriers and facilitators to the implementation of consultation planning" potx

Ngày tải lên : 11/08/2014, 05:22

... attention to CP According to the trainee interviews, three of the five implementing resource centers had the explicit support of their Boards of Directors, including the executive directors One ... patients in the decision-making process, thereby making it futile to attempt to implement visit preparation interventions Discussion Main findings A primary finding of our interviews was that 14 of ... organizations) reacted to CP? Trainee views of interactions with patients Two major themes emerged in the trainee interviews related to delivering the intervention to patients: the sense of trainee satisfaction...

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báo cáo khoa học: " Training community resource center and clinic personnel to prompt patients in listing questions for doctors: Follow-up interviews about barriers and facilitators to the implementation of consultation planning" pdf

Ngày tải lên : 11/08/2014, 16:21

... attention to CP According to the trainee interviews, three of the five implementing resource centers had the explicit support of their Boards of Directors, including the executive directors One ... patients in the decision-making process, thereby making it futile to attempt to implement visit preparation interventions Discussion Main findings A primary finding of our interviews was that 14 of ... organizations) reacted to CP? Trainee views of interactions with patients Two major themes emerged in the trainee interviews related to delivering the intervention to patients: the sense of trainee satisfaction...

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Báo cáo sinh học: "Heterogeneity of variance components for preweaning growth in Romane sheep due to the number of lambs reared" doc

Ngày tải lên : 14/08/2014, 13:21

... be of interest to update the parameters for field data We did not find any spurious changes in the maternal EBV of ewes rearing twin lambs for the first time after having reared single lambs the ... influence on the ability of the ewe to rear two lambs but not on her ability to suckle a single lamb Our results for the relative importance of the litter effect (7 to 12%) are in the range of ... responsible for the current genetic evaluation for pre-weaning growth All authors have been involved in drafting the manuscript and proofing and have approved the final manuscript Competing interests The...

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belief in god an introduction to the philosophy of religion oct 2005

Ngày tải lên : 10/06/2014, 21:54

... For God to know (with infallible certainty) that he was going to intend to something would be for him already to intend to that thing So, to preserve the claim that God genuinely changes in the ... deserve to be proud of what they win because the arguments that they use are ones they themselves have tested in the most intense ﬁres that their minds and those of others could stoke Of course they ... within the last four of these properties are artiﬁcial I should stress a consequence of this before I go on: my dividing the essential properties of God into nine, rather than dividing them into...

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Báo cáo sinh học: "Evidence for large domains of similarly expressed genes in the Drosophila genome" docx

Ngày tải lên : 06/08/2014, 18:20

... size increases from two to eight genes, the net number of genes in groups (that is, the genes in groups in the ordered dataset minus genes in groups from the random dataset) increases linearly ... neighboring genes or chromatin regions are important for the expression of individual genes For example, otherwise identical transgenes inserted into different chromosomal sites show varying levels of ... window size of about ten genes, the net number of genes begins to plateau (Figure 1) This suggests that most groups include about ten genes, so we used a window size of ten for the remainder of...

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báo cáo khoa học: " Identification of differentially expressed genes induced by Bamboo mosaic virus infection in Nicotiana benthamiana by cDNA-amplified fragment length polymorphism" pps

Ngày tải lên : 11/08/2014, 11:21

... containing three transmembrane domains and one RING-H2 domain The RING domain is reported to interact with E3-ubiquitin ligases mediating ubiquitination and degradation of the protein by the proteasome ... the accumulation of BaMV Knocking down the expression levels of these host genes using the VIGS system enables the identification of the novel functions of genes in pathogen-host interactions FNR ... expressed genes Effect of gene-specific knockdown on the accumulation of BaMV To investigate the roles of the differentially expressed genes identified by cDNA- AFLP analysis in BaMV infection cycle, the...

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báo cáo khoa học: " Identification of differentially expressed genes associated with semigamy in Pima cotton (Gossypium barbadense L.) through comparative microarray analysis" docx

Ngày tải lên : 11/08/2014, 11:21

... allow pinpointing of the semigamy gene However, there were several interesting genes in the group that deserve a closer examination It should also be pointed out that 17 of the differentially expressed ... step in gossypol synthesis in cotton, was found to be up-regulated in semigametic anthers and ovules Another common finding was the down-regulation of cytoskeletal proteins, such as a-tubulin [GeneBank: ... catalyzes the first step in photosynthetic CO2 assimilation and is the overall rate limiting step of photosynthesis [11] As a preliminary probe into any effects of semigamy on the photosynthetic...

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Báo cáo y học: "Statistical tools for synthesizing lists of differentially expressed features in related experiments" docx

Ngày tải lên : 14/08/2014, 20:22

... T(qmax) in our previous procedure does not take into account the uncertainty of the margins of the table (since they are all considered fixed) i =1 for the four cells in the × contingency table (indexes ... (FNR) for case A2 The FDR is calculated as the ratio of the false positives to the number of genes called in common, while the FDR is calculated as the ratio of the false negatives to the number of ... supposes that the list of genes is divided into four groups: genes differentially expressed in both experiments, genes differentially expressed in only one of the two experiments, and genes differentially...

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Some studies on a probabilistic framework for finding object-oriented information in unstructured data

Ngày tải lên : 23/11/2012, 15:04

... search engine for finding object on the web The thesis presents an investigation into the problem of searching for object, plausible solutions related to the problem In particular, the main objectives ... compute the ids of the top ranking documents - For each query word, compute the matching positions of that word in each of the top-ranking documents - For each of the top-ranked documents, given the ... a lot of controversies in information retrieval community lately The main object of the thesis is implementing the approach based on machine learning for ranking and building the modules to support...

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Tài liệu Báo cáo khoa học: Identiﬁcation of differentially expressed genes of the Paciﬁc oyster Crassostrea gigas exposed to prolonged thermal stress docx

Ngày tải lên : 18/02/2014, 16:20

... expression of organisms subjected to thermal stress are known to involve major adjustments in the expression of ribosomal genes and genes coding for proteins involved in RNA metabolism and protein synthesis ... chaperones, the chaperonin-containing TCP1 (subunit 7, isoform b) presented the same expression pattern in response to heat stress in our study This complex, involved in folding actin, tubulin and cyclin ... severity of the thermal stress under our experimental conditions A number of genes encoding structural components of the cytoskeleton and proteins involved in contractile functions (including actin,...

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Báo cáo khoa học: Molecular identiﬁcation and expression study of differentially regulated genes in the Paciﬁc oyster Crassostrea gigas in response to pesticide exposure doc

Ngày tải lên : 30/03/2014, 15:20

... occurred in the transamination process, again, related to the formation of nitrogenous end products [64] For the other differentially transcribed genes identiﬁed in our libraries, we found no information ... b-1,3-Glucan binding protein 3e-6 Procathepsin L 1e-12 Meningioma expressed antigen 7e-19 Lipoprotein receptor related protein 2e-24 Fucolectin-1 6e-4 Cytoskeleton Tubulin alpha chain 4e-40 Tubulin beta ... change, allowed to maintain the oysters in a more or less homogenous concentration of contaminants Most of the genes we identiﬁed function in the respiratory chain, cell communication, the immune...

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