answer the following questions that relate to the analysis of chemical compounds

Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt

Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt

Ngày tải lên : 23/03/2014, 04:20
... binds to mitotic pro- moters in the S phase and mediates their activation [4,5]. The composition of the S-phase complex differs from that of the G0 complex. Specifically, in the S phase, the interaction ... results provide the basis for a further investigation of the regulation of the cdc2 promoter by LINC in different phases of the cell cycle. Discussion The primary goal of this study was to investigate LIN54, ... selection of target genes. Although the primary focus of this study was to characterize LINC binding in quiescent cells, our results provide the basis to further investigate the regulation of the cdc2 promoter...
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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

Ngày tải lên : 25/10/2012, 10:06
... Miami, FL), that continuously delivers racemic MPH when applied to intact skin [22]. The dose of drug delivered depends on the surface area of the patch and the length of time that the patch is ... TEAEs of decreased appetite and insomnia, the majority of caregiv- ers agreed that the medication caused their child to want to eat less, and approximately one-third of caregivers agreed that the ... satisfied with the efficacy of the study medi- cation on their child's attention. The majority of caregiv- ers (93.1%) indicated a high level of satisfaction with the duration of effect of the study...
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Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf

Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf

Ngày tải lên : 19/02/2014, 02:20
... cancer, fibrosis and autoimmune disorders. Signa- ling is initiated by binding of the cytokine to a homodimeric complex of cytokine receptor type II, which recruits type I receptor and activates it ... MAN1 and all regulatory Smads (BMP and TGFb-responsive) but not the co-Smad or the inhibitory Smads [13–17]. The interaction was mapped to the RR-motif in MAN1 and the MH2 domain of R-Smads (Fig. ... discovered as one of the autoantigens for the autoantibodies from a patient with collagen vascular disease [18]. MAN1 is an integral membrane protein of the INM and belongs to the LEM (Lap2- emerin-MAN1)-domain...
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Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx

Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx

Ngày tải lên : 19/02/2014, 07:20
... at pH 7. These preferred activities of the two PPOs of R. solanacearum are opposite to the names assigned to them when the genome of this bac- terium was sequenced and the function of these con- ceptual ... is related to virulence of the infective micro-organism, but it is also related to defensive roles in the infected cell, so that the place and time of triggering of melanogenesis must be key to the ... logical according to the mathematical algorithm used for the blast search. Score and e values depend on several factors, but mostly the total length of the sequence used for the blast. The shorter...
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WHY IT IS SO HARD TO GET SAFE WATER TO THE POOR – AND SO PROFITABLE TO SELL IT TO THE RICH pdf

WHY IT IS SO HARD TO GET SAFE WATER TO THE POOR – AND SO PROFITABLE TO SELL IT TO THE RICH pdf

Ngày tải lên : 07/03/2014, 00:20
... significantly. Why then do poor people not use them ? It seems to be difficult to persuade the poor to use them, and to ensure that those who have been persuaded continue to use them. The problem seems to ... INDIA The success of tea as a form of selling the concept of boil- ing water was – similar to the miracle of the bottled water markets – a clever marketing strategy. The fact that lots of money ... tested the efficiency of the filter in the laboratory and in the field and conclude : " Results agree with historical data and show that the PFP filter is capable of removing almost 100 % of...
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Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

Ngày tải lên : 07/03/2014, 09:20
... is the first time that the binding of a protein component at the active site has been described for a STP. Given that the interaction would resemble that of the actual complex, we were able to ... CovR ⁄ CsrR. The motif is located at the surface of the SaPPase (Rantanen, unpublished), and superposition of the prolines allows superposition of the serine Ocs – but not the rest of the putative ... bound than the M3 in MtSTP. Crystal contacts at the active site The differential occurrence of the metal ions correlates with the conformation of the flap subdomain (132–174) and the ‘binding’ of adjacent...
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Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx

Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx

Ngày tải lên : 07/03/2014, 12:20
... cells and show that these marks occur independently of the recruitment of any lineage-specific transcription factors such as PU.1. Furthermore, they observe the presence of components of the TFIID ... analyzed recruitment of factors to the a-globin gene locus dur- ing the differentiation of erythroid cells. The regula- tory elements located upstream of the a-globin genes also appear to initiate the activation ... indi- cating that dimethylation of H3K4 and recruitment of RNA Pol II and TBP to the LCR occurs before acti- vation of any of the globin genes. The presence of H3 dimethylated at K4 indicates that these...
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CREDIT CARDHOLDERS’ BILL OF RIGHTS ACT OF 2008: Mr. FRANK of Massachusetts, from the Committee on Financial Services, submitted the following ppt

CREDIT CARDHOLDERS’ BILL OF RIGHTS ACT OF 2008: Mr. FRANK of Massachusetts, from the Committee on Financial Services, submitted the following ppt

Ngày tải lên : 15/03/2014, 07:20
... Pursuant to clause 3(c)(3) of rule XIII of the Rules of the House of Representatives, the following is the cost estimate provided by the Congressional Budget Office pursuant to section 402 of the ... intended to employ a variety of factors to insure that cardholders were charged rates that reflected the default and other risks they pose to creditors. In addition, credit card issuers began to ... vote of 39 yeas and 27 nays. C OMMITTEE V OTES Clause 3(b) of rule XIII of the Rules of the House of Representa- tives requires the Committee to list the record votes on the motion to report...
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Báo cáo khoa học: Concerted mutation of Phe residues belonging to the b-dystroglycan ectodomain strongly inhibits the interaction with a-dystroglycan in vitro pot

Báo cáo khoa học: Concerted mutation of Phe residues belonging to the b-dystroglycan ectodomain strongly inhibits the interaction with a-dystroglycan in vitro pot

Ngày tải lên : 16/03/2014, 12:20
... position 718, belonging to the putative a-DG-binding epitope (691–719) within the ectodomain of b-DG, was found to be one of the most influenced residues during the titration of [ 15 N]b-DG(654–750) ... thioredoxin-a-DG(485–620) [15]. Therefore, we decided to mutate it to an alanine, together with two other phenylalanines, Phe692 and Phe700, the only other aromatic residues located within the a-DG-binding epitope that ... linking the F-actin cytoskele- ton to the extracellular matrix. Dystroglycan is thought to play a crucial role in the stability of the plasmalemma, and forms strong contacts between the extracellular...
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The complete idiot s guide to the perfect interview (2000)

The complete idiot s guide to the perfect interview (2000)

Ngày tải lên : 20/03/2014, 12:16
... 8:28 AM Page 22 x The Complete Idiot’s Guide to the Perfect Interview, Second Edition 9 How to Answer the Questions Everybody Asks 91 First, Speak the Language of Business 91 The Answers You Should ... 0-02-863890-5 Library of Congress Catalog Card Number: 00-100787 020100 87654321 Interpretation of the printing code: the rightmost number of the first series of num- bers is the year of the book’s printing; the ... number of the second series of numbers is the number of the book’s printing. For example, a printing code of 00-1 shows that the first printing occurred in 2000. Printed in the United States of America Note:...
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Submitted to the Committee on Preventive Services for Women Institute of Medicine pot

Submitted to the Committee on Preventive Services for Women Institute of Medicine pot

Ngày tải lên : 28/03/2014, 14:20
... 1960s marked the beginning of the era of modern contraceptive use. The pill remains the most popular form of reversible contraception in the United States today. The advent of the pill allowed ... women found that 52% of them were worse off financially than the year before. Of those who were worse off, three-quarters said that they could not afford to have a baby right then. And while ... pills, amounting to $14 per pack, on average. The same study found that the out -of- pocket expenditures for a full year’s worth of pills amounted to 29% of the women’s annual out -of- pocket expenditures...
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Stress and Performance - A Review of the Literature and Its Applicability to the Military pdf

Stress and Performance - A Review of the Literature and Its Applicability to the Military pdf

Ngày tải lên : 29/03/2014, 18:20
... affects or event the event performance Moderator 1 (Type 1) Moderator 2 (Type 2) Factors that affect Factors that affect the the individual’s effect of stress on response to the stressor: performance: Training ... in the face of stress. For cases in which moderators could be both types, the author classified each moderator into what appears to be the most common manifestation of the moderator. In the ... own appraisal of the event. Their work suggests that the physiological stress response is the result of the individual’s interaction with the environment and interpretation of the event, based...
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The Blood Cold Chain Guide to the selection and procurement of equipment and accessories pptx

The Blood Cold Chain Guide to the selection and procurement of equipment and accessories pptx

Ngày tải lên : 31/03/2014, 12:20
... on the management of the inventory and the effectiveness of the blood cold chain, and is a waste of a scarce and valuable resource. WHO recognizes that there are differences in the handling of ... bank refrigerators include: 1 Castors or wheels that enable the equipment to be moved easily 2 Glass-fronted doors that allow easy viewing of blood stocks 3 Door lighting that further improves the view of ... of the blood stocks in the refrigerator 4 ‘Door open’ alarm facility that alerts users to close the door immediately after use 5 Door lock, which improves the security of the contents of the...
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Welcome to the Creative Age - Bananas, Business and the Death of Marketing

Welcome to the Creative Age - Bananas, Business and the Death of Marketing

Ngày tải lên : 06/06/2014, 08:44
... rein- forced the received wisdom: our ability to measure things, to test hypothe- ses systematically, to point to the facts of a situation has served to push the value of creativity to the margins of our ... smaller print at the top of the label, above a childish illustration of a toy train, the branding, ‘Fruit on the Move’. I bought two of these: one to eat immediately and one to store in my coolbox ... parts of R&D – even then, we like to wall these people off, to keep them safe from the rest of us. We certainly don’t trust them with levers of power – or only rarely. Yet behind the suit often...
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