an overview of aggression and dominance relationships

Báo cáo Y học: Environmentally coupled hydrogen tunneling Linking catalysis to dynamics potx

Ngày tải lên : 31/03/2014, 23:20

... (1998) Hydrogen exchange and protein folding Curr Opin Struct Biol 8, 112–118 Englander, S.W., Sosnick, T.R., Englander, J.J & Mayne, L (1996) Mechanisms and uses of hydrogen exchange Curr Opin Struct ... k affecting the rate of H and D transfer to almost equal extents and with gating being the principal determinant of the temperature dependence of the KIE Thus, this model can provide unique insight ... weakness of the amide exchange technique is uncertainty regarding the mechanism of exchange, and many workers consider amide exchange as indicative of protein ﬂexibility rather than dynamics [40–42]...

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Báo cáo y học: "Polymorphisms in melatonin synthesis pathways: possible influences on depression" pdf

Ngày tải lên : 10/08/2014, 09:20

... and bipolar disorder DNA, to exclude participants of non-European ancestry, and the MrOS and SOF participants were all known to be of European ancestry Three AANAT SNPs, rs11077821, rs8150, and ... AG027574, R01 AG027576, and R01 AG026720 We thank the study staff at each site and all the men and women who participated in each of these studies Susan Leckband, Alexandra P Grizas, and Elizabeth K ... developed the circadian and AIMs SNP panels and consulted on all statistical analyses GJT arranged for the genotyping of the MrOS and SOF samples and supervises analyses of these genotypes SSM called...

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Báo cáo y học: " Environmental exposures and their genetic or environmental contribution to depression and fatigue: a twin study in Sri Lanka" potx

Ngày tải lên : 11/08/2014, 16:22

... non-significant (OR 1.20, 0.94-1.55), and standard of living which only showed a significant association in men The strength of the association varied by sex only for standard of living (OR 1.60 in men and ... Colombo District of Sri Lanka, an area with population of 2.2 M which includes the island’s capital, and varies from urban to semi-urban areas We added a question to the update of the annual census, ... statistical analyses and wrote the first draft MH and AS were principal investigators, responsible for study’s design and implementation MH and PMcG supervised the statistical analyses and their...

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Báo cáo y học: "Virus-derived transgenes expressing hairpin RNA give immunity to Tobacco mosaic virus and Cucumber mosaic virus" pdf

Ngày tải lên : 11/08/2014, 21:22

... professor Johansen, Danish Plant and Soil Graduate School) between the PstI and BamHI site The plasmid pSK-In-ΔRep was digested by SalI and BamHI, and inserted into the SalI and BamHI site of ... plants There were no differences in the plant height and seed weight between the inoculated transgenic immune plants and healthy non-transgenic plants (Table 3) Accumulation and composition of ... or CMV Comparative analysis of the T2 or T4 transgene and the mode of expression in terms of resistance Correlation between the number of transgene insertions and the type of RNA silencing in...

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Báo cáo y học: "Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells" pdf

Ngày tải lên : 13/08/2014, 09:21

... monkeys, but not from humans and mice) In this drawing, stick figures represent sources of A3 proteins and not targets of infection A3G isoforms from human and non-human primates, and Vif from SIVagm ... entry and uncoating, reverse transcription is initiated and viral minus-strand cDNA is synthesized During this process, these APOBEC proteins attack newly synthesized minus-strand cDNAs and introduce ... Salomoni P, Pandolfi PP, Luban J: As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity J Virol 2003, 77(5):3167-3180 Hatziioannou T, Cowan S, Goff SP, Bieniasz...

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Báo cáo y học: "Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentatio" ppt

Ngày tải lên : 13/08/2014, 11:22

... found in multiple avian species and other animals H1, H2, and H3 predominate in human disease seasonally, and more recently, avian subtypes such as H5 and H7 have increased in humans over the past ... complications and fulminant disease [77-79] The most significant and severe disease syndromes are found in lung, liver, kidney, and heart transplant recipients [80] Significant morbidity and mortality ... after the onset of rash, and can progress to respiratory failure and ARDS [56,57] Risk factors for VZV pneumonia and ARDS include pregnancy, smoking, and immunosuppression (malignancy, corticosteroids,...

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A study of the mechanisms of immunity to pasteurella haemolytica infection

Ngày tải lên : 30/09/2015, 05:52

... Huggins, and a similar Enumeration Miles, and allowed and against inocula OD Figure Standard A6, Figure A7 and AB against Standard Al, curves of A2 curves and A5 of against P types haemolytica OD at ... haemolytic 48 hours Cultures and organisms, and pneumonic (Spray, bacilli (1932) "typical" biochemical were and and "typical" was similar The "atypical" were which organisms, and to an cocco- Newsom haemolytic ... haemolytica A and 1,2,5, belong to ?.U to and biotype (Biberstein sations in P two that than of T of Serotypes now considered 3,4 serotypes investigation An less 12 are and (1960) Knight and Thal, of to...

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Linking the linguistic to the social

Ngày tải lên : 01/11/2013, 08:20

... New York and Detroit as separate speech communities as well, and within New York and Detroit it is common to speak of separate African American and European American speech communities And if one ... and female (as in the case of male and female; girl and boy) In other cases, the relation between a linguistic sign and social gender can be secondary For example the adjectives pretty and handsome ... decades 74 Language and Gender way in which this happens is in the opposition between ‘‘standard’’ and ‘‘nonstandard’’ grammar Many speakers of English can choose between simple and multiple...

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Tài liệu From Great Depression to Great Credit Crisis: Similarities, Differences and Lessons pdf

Ngày tải lên : 16/02/2014, 03:20

... vs Then (7 country average) Source: Bernanke and Mihov (2000); Bank of England, ECB, Bank of Japan, St Louis Fed, National Bank of Poland, Sveriges Riksbank 42 150 140 130 120 110 100 90 10 1925=100 ... fixed-effects estimation and RE stands for random-effects estimation In the IV models, DG and r are instrumented with the change in defence spending and a gold standard dummy 32 Table 2: Panel Regressions ... planned changes in federal tax revenues prior to the legislative process 47 48 See Canova and Denicoló (2002) and Uhlig (2005) for monetary shocks, or Canova and Pappa (2007) and Mountford and...

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Tài liệu Indigenous Knowledge Local Pathways to Global Development doc

Ngày tải lên : 16/02/2014, 10:20

... one of the prime means for transmitting, accumulating, enhancing, and transforming IK; and traditions of indigenous knowledge and learning may themselves offer models or patterns for organizing ... one of the best hopes for treating and stemming the spread of AIDS But healers rely on medicinal plants and there has been a significant decrease in the abundance of many important medicinal plant ... hides, building materials, incomes, and a source of inspiration Rivers provided transportation and fish, and water and soils provided a permanent source of sustenance It is well documented that traditional...

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Tài liệu Báo cáo khoa học: A genetic screen identifies mutations in the yeastWAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation docx

Ngày tải lên : 19/02/2014, 00:20

... Expression and stability of the wild-type and mutant War1p variants Cultures of the strains YAK111 (WT-3HA), YBB31 (28-3HA), YBB30 (42-3HA) and YPH499 (WT) were grown in YPD to an A600 of and harvested ... strains and subjected to DNA sequencing Sequencing of both DNA strands of War1-28 identiﬁed an A to T mutation at position 1286, and a change of C to T at position 1288, the latter introducing a translational ... reading of the manuscript and helpful discussions Peter Piper and Mehdi Mollapour are acknowledged for sharing unpublished information and their long-standing collaboration We appreciate the gifts of...

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Tài liệu Báo cáo khoa học: Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing pdf

Ngày tải lên : 20/02/2014, 11:20

... of DNA duplexes I and II to the formamidopyrimidine-DNA glycosylase (Fpg protein) (lanes and 4, respectively) is presented Lanes and show DNA duplexes I and II, respectively, in the absence of ... Results and discussion Design of modiﬁed DNA duplexes E coli Fpg protein recognizes a hexanucleotide sequence with oxoG in the middle in the lesion-bearing DNA strand and speciﬁcally binds to it and ... SDS/2-mercaptoethanol solution at 95 °C The gels were analyzed by autoradiography and silver staining Equal mobilities of the radioactive and the protein-containing bands indicated covalent attachment of DNA...

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Báo cáo khoa học: Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model doc

Ngày tải lên : 06/03/2014, 11:20

... and 250, one of which (248) is a hotspot location in human skin cancer [54] Tobacco smoke-associated lung cancer Tobacco smoking causes lung cancer and tobacco smoke contains many thousands of ... nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers Oncogene 16, 1241–1247 Vineis P & Husgafvel-Pursiainen K (2005) Air pollution and cancer: ... to DNA and its consequences EXS 99, 87–110 Hanahan D & Weinberg RA (2000) The hallmarks of cancer Cell 100, 57–70 Hainaut P & Hollstein M (2000) p53 and human cancer: the ﬁrst ten thousand mutations...

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Báo cáo khoa học: Linking pseudouridine synthases to growth, development and cell competition potx

Ngày tải lên : 06/03/2014, 22:21

... kb variant mRNA (B) Main properties of the 46279 and 46282 transgenic lines, each carrying an independent insertion of the 16822-silencing transgene on chromosome 2, and of the 34597 and 34598 ... nub–GAL4 male adult flies (A, C) and their + ⁄ en–GAL4 and + ⁄ nub–GAL4 respective controls (B, D) were analysed to determine total wing area, size of A and P compartments, and their ratio (A ⁄ P) Cell ... silencing of an independent gene The two lines, named 34597 and 34598, exhibited a silencing A Fig Structure and expression of mfl-silencing constructs (A) Schematic structure of the four mfl mRNA isoforms...

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Báo cáo khoa học: Cotton GhMPK2 is involved in multiple signaling pathways and mediates defense responses to pathogen infection and oxidative stress doc

Ngày tải lên : 14/03/2014, 23:20

... pathways L Zhang et al A B C Fig Enhanced viral resistance against TMV and CMV in transgenic tobacco plants overexpressing GhMPK2 (A) Leaf and root symptoms of tobacco plants infected with TMV and CMV ... Expression of the defense-related genes and ET biosynthesis genes in transgenic and wild-type plants (A) The mRNA levels of defense-related genes and ET biosynthesis genes in transgenic and wild-type ... determined by northern blot analysis The mRNA levels of CAT1 and APX, and particularly of MnSOD and GST, were greatly upregulated in the transgenic plants, whereas RbohD transcripts showed no obvious...

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Báo cáo Y học: Evaluation of two biosynthetic pathways to d-aminolevulinic acid in Euglena gracilis potx

Ngày tải lên : 17/03/2014, 17:20

... succinyl CoA (5iv and 5v), giving rise to succinyl CoA (5iv and 5v) labeled with 13C on C-4 and C-1 in equal quantity Part of succinyl CoA (5iv and 5v) labeled with 13C on C-4 and C-1 goes into ... of ALA (3) was 4.1-fold, that of carbons (C-1, C-3, C-6, C-8, C-11, C-13, C-17 and C-19) derived from C-4 of ALA (3) was 4.1-fold, and that of carbons (C-4, C-5, C-9, C-10, C-14, C-15, C-16 and ... s, and the number of scans was 15 000±18 000 The assignments of 13C-NMR signals of chlorophyll a (1) and methyl pheophorbide a (2) were made on the basis of reported data [23±28] Calculation of...

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Báo cáo khoa học: " Linking Events and Relations to Timestamps" pptx

Ngày tải lên : 24/03/2014, 03:20

... lower number of event instances, we made use of the annotated event-coreference as a sort of closure to add more instances: if events A and B corefer, and there is a link between A and time expression ... system, performance baseline and lessons learned In Proceedings of 192 the 22nd National Conference for Artiﬁcial Intelligence, Vancouver, Canada, July Branimir Boguraev and Rie Kubota Ando 2005 Timeml-compliant ... between B and t This was not explicitly expressed in the data For the task at hand, we used gold standard annotations for timestamps, events and relations The task was thus not the identiﬁcation of...

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Báo cáo khoa học: An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector pot

Ngày tải lên : 30/03/2014, 02:20

... NIH Grants HL56712 and HL79389 (to Ke-He Ruan) In addition, we thank R Kulmacz and Lee-Ho Wang for providing the original wild-type cDNAs of human COX-1 and PGIS, respectively We also thank Anita ... substrate for downstream synthases, and is isomerized to prostaglandin D2, prostaglandin E2 (PGE2), prostaglandin F2 (PGF2), and prostaglandin I2 (PGI2) or thromboxane A2 (TXA2) by individual synthases ... (1978) Prostaglandins and thromboxanes Annu Rev Biochem 47, 994–1030 Smith WL (1986) Prostaglandin biosynthesis and its compartmentation in vascular smooth muscle and endothelial cells Annu Rev Physiol...

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Báo cáo khoa học: The relative contribution of mannose salvage pathways to glycosylation in PMI-deﬁcient mouse embryonic ﬁbroblast cells pdf

Ngày tải lên : 30/03/2014, 04:20

... inhibitor of lysosomal a-mannosidase and of the Golgi complex a-mannosidase II [21] Bafilomycin A1 is a highly specific inhibitor of vacuolar-type H+-ATPase [22], and inhibits acidification and degradation ... concentrations of glucose and mannose, human fibroblasts can derive about 70% of the mannose in N-linked chains from mannose, and about 10% of the transported mannose is used for glycosylation, ... One microgram of linearized plasmid was diluted with 200 lL of Opti-MEM, and then mixed with 200 lL of lipofectamine solution, dissolving lL of Lipofectamine 2000 in Opti-MEM, and transfected into...

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Báo cáo khoa học: Irreversible cross-linking of heme to the distal tryptophan of stromal ascorbate peroxidase in response to rapid inactivation by H2O2 ppt

Ngày tải lên : 30/03/2014, 08:20

... Ministry of Economy, Trade and Industry of Japan References Asada K (1999) The water-water cycle in chloroplasts: scavenging of active oxygens and dissipation of excess photons Annu Rev Plant Physiol ... (Millipore) and eluted with 60% acetonitrile and 0.1% formic acid for analysis using a Q-TOF Ultima mass spectrometer (Waters Co., Milford, MA, USA) MS and MS ⁄ MS data were acquired and processed ... of a distinct mechanism of inactivation is supported by the difference in the spectral changes for H2O2-treated tsAPXW35F and tsAPX (Fig 6A,B) Discussion Fig Absorption spectra of tsAPX (A) and...

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