... is ofthe opinion that the northern areas ofthe Malay Peninsula beginning from Kedah and extending to the southern region of Siam are part of a (traditional) Mon-speaking area The presence of ... Leonard Andaya (on the Sunda Zone /the Malacca Straits /the Sea of Melayu) and Heather Sutherland (on the Java Seas), to name just a few, in perceiving Southeast Asia within a wider zone, using the ... world systems of pre-colonial Southeast Asia, namely, the worlds ofIndiaandChinaThe Indian world system referring to the Indian Ocean system, for instance, remained 21 Examples of Hokkien family...
... across the Russian Plain duringthe Briansk Interstadial with the southern limit ofthe range of a number of Arctic plants being 1200 km further south than today (and a further 600 km during ... two-thirds ofthe British Isles, Scandinavia, the Baltic andthe Alps Much ofthe remainder of Europe north ofthe Mediterranean had a cover of permafrost (CLIMAP, 1976; Maarleveld, 1976) Away from the ... kyr, African glacial stages were more arid than those ofthe middle Pleistocene (Jahns et al., 1998) The complexity ofthe African climate is the result ofthe size and heterogeneous nature of the...
... sense and antisense strands ofthe piRNA hairpin are involved in formation ofthe piRNA-interacting complex (piRC) and function in the transcriptional gene silencing of retrotransposons and genetic ... positions and sequences used to amplify pri-miR9-1, 9-2 and 9-3 Arrows indicate the position and orientation ofthe primers Bold font represents the sequence of mature miR9* and italic fonts the sequence ... vector The promoter sizes ofthe construct are indicated by numbers in parentheses )44 means located 44 bp upstream ofthe first base pair at the 5¢-end of pre-miR-9-1 defined as +1 FLuc is the ORF of...
... characterization ofthe thermally induced aggregation of SK using a variety of techniques The results provide us with some ofthe properties of these high molecular mass aggregates and help to delimit the ... with the thermal unfolding of SK occur at pH 7.0 and high sample concentrations and at pH 6.0 at all concentrations The effect ofthe temperature scan rate on the DSC curves of SK at pH 7.0 and ... the fitting and correspond to the values obtained for the isolated domains The uncertainties ofthe parameters correspond to the standard errors obtained in the fittings Reproducibility of Tm and...
... on whether the pregnancy history ofthe parents qualifies them to have a (new) child, and whether the child quota laid down in the yearly plan ofthe village or workplace is full or not The rules ... [2] Parallel to the hierarchical structure of civil servants, there is the party organization, andthe leaders ofthe party at each level share the decision making with leaders ofthe civil servant ... Anhui Province, the outcome of pregnancies varied considerably according to the legal status ofthe pregnancy [8] The number of abortions increased rapidly after the introduction ofthe 1979 population...
... amount of military aid to the defence of Virginia! Gov Wise had several companies ofthe military present on the day ofthe execution of John Brown and others, and assured the Governor ofSouth ... conduct ofthe negroes for the first nine months after their liberation, up to the middle of 1794 Ofthe conduct ofthe negroes duringthe year 1795, and part of 1796, I find no account Had there ... scattered the negroes; they had killed about and wounded 12 more In their flight some of them shot themselves, others their wives, and then themselves; some absconded a few days, and then killed themselves...
... so that I just literally pull my own teeth They’ll break off after a while, and then you just grab ahold of them, and they work their way out.” We ask how she can face the pain of pulling out her ... years During those years, her status has shifted: once a member ofthe working class, she is now a member ofthe caste ofthe ill, the infirm, andthe marginally employed—a group often called by the ... noted—“they can’t squeeze blood from a turnip.” 14 INTRODUCTION Middle-class Americans saw themselves as part ofthe American mainstream They shared American values of family and work, they saw themselves...
... day and returned on day 14 to the level of control mice at day The expression of cystatin B was increased about twofold on day ofthe acute stage (Fig 3a) Like the expression of cathepsins, the ... of proinflammatory cytokines on days andThe downregulation of cathepsin K on day could be another example ofthe fact that the time course of cytokine expression determines the time course of ... (Fig 2b) and found a significant downregulation at the mRNA level on day but no alteration of expression at the mRNA level on the other days in the course of AIA Not only were MMPs and cathepsins...
... in the LN than in the SM [19], in line with the different mode of induction ofthe disease, which favors spread ofthe arthritogen to the regional LNs [23] Both the pathology andthe sequence of ... induction of disease (day 0), at hours after injection ofthe arthritogen, and on days 1, 3, andofthe disease, the latter time point marking the transition to the chronic phase For the sake of clarity, ... potential therapeutic use if performed at the outbreak of disease [30,31] The marked elevation of both IFN-γ and IL-2 mRNA at the primary site of pathology, in contrast to the modest elevation of these...
... Yudoh and colleagues [1] further analyzed the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional inactivation of ... chondrocytes [11] Conclusion The results provided in the study by Yudoh and colleagues and previous reports by us and other groups strongly support the notion that HIF-1 is of pivotal importance in ... importance in cartilage development and homeostasis Furthermore, given the decreased oxygen levels and presence of inflammatory mediators duringthe course of OA, a causal role for HIF-1 in preventing...
... severity of multiple organ dysfunction rather than the severity of sepsis and systemic inflammation and there are no data available as to the relation of PCT concentrations andthe severity of multiple ... categories ofthe SOFA to which patients were assigned, andthe median and 25/75 and 10/90 percentiles were determined Differences of median PCT levels between these SOFA groups were analyzed by the ... different groups of patients, eg for purposes of differential diagnosis, assessment ofthe severity ofthe disease andof systemic inflammation, including the severity of MODS, is mandatory When...
... the type ofand severity of trauma according to a system of points based on injury to six regions ofthe body [10] The ISS is defined as "the sum ofthe square ofthe highest points in each of ... in 9% ofthe patients on day after trauma, in 24% ofthe patients on day 2, and in 23% ofthe patients on day Even on day after trauma the peak levels of CRP were reached in another 15% ofthe ... College of Chest Physicians/Society of Critical Care Medicine criteria [13], andthe occurrence of organ dysfunction The final data analyzed were 28-day survival data The type ofand severity of trauma...
... to 'remove the gloves' The education and infection control team simulated every step ofthe dressing and undressing to ensure safety and clarity, and then scripted and photographed the process ... management and infection control The group then observed two educators describing and demonstrating the dress-up andthe dress-down method for the PPS Next, the group was divided into two sets of four ... tachycardia, and ventricular fibrillation) We timed how long it took the first person to don the PPS The other four trainees observed After the simulation we debriefed the entire group and discussed and...
... duringthe last decade (1995–2004)* * For each ofthe large-scale events in the above three categories, the occurrence in the same location ofthe other two types of events, regardless of their ... define the extent to which the occurrence of one type of disaster enhances the risk of another Authors' contributions PBS conceived ofthe study, designed the research plan, supervised the literature ... co-wrote the paper, undertook the literature review PS assisted in the critical interpretation ofthe intellectual content and drafting ofthe paper Competing interests The authors and their institutions...
... synchrony The data should speak for themselves 7) The DNA distribution of cells should be narrow in the synchronized cells and these distributions should then reflect the movement of cells through the ... wishes to look at the response of genes to perturbation, then it is a good experiment The problem is whether the methods of Whitfield et al lead to an understanding of what happens in the normal, unperturbed ... the comparison ofthe two experiments, I present a graph (Figure 1) ofthe K values in a scatter diagram The R2 value is 0.37, which some may say is "rather strong" and others may say is "rather...
... Experimental set up and overall expression profiles Experimental set up and overall expression profiles (a) The time course of gene expression was determined duringthe response of two different ... our gene sets and noted significant enrichment of several of these categories (Additional data file 2) Moreover, the response of lung fibroblasts with regard to the expression of these genes could ... cluster view ofthe 1,379 Class II clones showing differential expression between serum and other GF treatment groups is shown The right hand side shows the expression profiles of these Class...
... 05) If the current status is the separation ofthe CEO andthe board of directors’ chairman andthe probability of a downward switch f(DS) is exactly 50, then a change to the combination ofthe ... resulting in a further sharp increase in the demand for external audits The establishment ofthe Shanghai and Shenzhen stock exchanges andthe promulgation of new accounting and auditing standards also ... effectiveness of audit monitoring in China To bolster the confidence ofthe market participants, the Chinese government should promote the reform of corporate governance ofthe listed firms and enhance the...
... by the management (Jensen and Meckling, 1976) Thus, a series of mechanisms or measures are imposed to bind the managers and to induce them to act in the best interest ofthe owners One ofthe ... the assurance provider andthe information intermediater Nonetheless, the utility ofthe auditing function depends upon audit quality which is determined by the independence of auditors andthe ... affairs ofthe firm; According to an investigation report that the share interest ofthe first large shareholder (mainly the parent SOEs) accounts for, on average, around 50% ofthe total equity of the...