... 6A,B). The protein content in the 8K-BLP-treated disks increased significantly, and wasAEBCDFig. 3. Determination of the structure of 8K-BLP. (A) MALDI-TOF MS analysis of the purified peptide. ... Members of the insulin-like peptide (ILP) family arepresent in a wide variety of metazoans. In vertebrates,insulin and insulin-like growth factors (IGFs) regulatemetabolism, growth, and development. ... Among these,bombyxins, a family of peptides produced by the brain of the silkmoth Bombyx mori, were the first to be dem-onstrated to have structural homology to vertebrateinsulins [7,8]. Bombyxin-II,...