... Bateman, Greg Haljan, Ehsan Y Davani, Yinjin Wang and Keith R WalleyUniversity of British Columbia Critical Care Research Laboratories, St. Paul&apos ;s Hospital, 1081 Burrard Street, Vancouver, ... inflamma-tory biomarkers such as C-reactive protein and D-dimer areassociated with an increased incidence of, and worse progno-sis for, cardiovascular disease [4-8]. However, whether thesemolecules ... are simply markers of the inflammatory process ormight actually play a causative role in the resultant organ dys-function is not known. We previously reported a novel two-step regulatory mechanism...