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Báo cáo y học: "Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R " pps

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Báo cáo y học: "Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A" ppsx

... lungs preserved with EuroCol-lins, is suggested to reflect a decrease in surfactant synthe-sis rather than an increase in surfactant secretion. Afterpreservation with Celsior, the size reduction ... which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Respiratory Research 2005, 6:60 http://respiratory-research.com/content/6/1/60Page ... release of surfactantphospholipids and SP-A may result from yet suboptimalpreservation procedures.Notably, Celsior preserved lungs had almost normalamounts of polymorphonuclear leukocytes and...
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Báo cáo y học: "Cell Cycle Arrest by a Natural Product via G2/M Checkpoint"

... (5-bromo-2'-deoxyuridine) cell proliferation assay and flow cytometric analysis, respectively. Specific cellular protein expressions were measured using Western blot analysis. Flow cytometric ... cytometric analysis indicated that CKBM induced G2/M cell cycle arrest and apoptosis, whereas differential protein expressions of p21, p53 and 14-3-3σ (stratifin) using Western blot analysis were ... Editor and Editor-in-Chief of Biological Signals and Biological Signals and Receptors, Adjunct Professor of University of Toronto and is Honorary or Visiting Professor of over ten universities....
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Báo cáo y học: "Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R." pps

... work is properly cited.ResearchCell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R Ge Li1, Hyeon U Park1,2, Dong Liang1,3 and Richard Y Zhao*1AbstractBackground: ... CEM-SS cells (Figure 7C).DiscussionIn this report, by using a single cell cycle assay, we dem-onstrated that Vpr induces cell cycle G2 arrest through arather unusual molecular mechanism. Vpr ... as shown by Chk1-Ser345 phosphorylation, in the S- phase of the cell cycle. Chk1-Ser345 Phosphorylation Is Exclusively Required for Vpr-induced G2 Arrest Our data and other early reports...
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Báo cáo y học: "CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase" ppsx

... of mRNA by real-time PCR (ABI PRISM7700 sequence detection system, Applied Biosystems, FosterCity, CA USA) using respective primers and SYBR Green.The primers of Fas ligand were designed using ... DMSO only. Results are representative of five OA cartilage samples. (c) FACS analysis of OA chondrocytes labeled by annexin V and PI distinguishes apoptosis from necrosis. Chondrocytes were labeled ... Ct1 8S , and ∆C =CtCTL - Ct1 8S .Statistical analysisStatistical analysis was performed by analysis of variance fol-lowed by a Tukey&apos ;s test for multiple comparisons at a rejectionlevel...
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Báo cáo y học: "CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase" pps

... Netherlands for providing post-processing software and helpful discussions.References1. Sibbitt WL, Sibbitt RR, Brooks WM: Neuroimaging in neuropsy-chiatric systemic lupus erythematosus. Arthritis ... processingAll analyses were performed by one observer. Using the soft-ware platform SNIPER (Software for Neuro-Image Processingin Experimental Research; Division of Image Processing,Department ... neuropsychiatric systemic lupus erythematosus; SLE, systemic lupus erythematosus.Arthritis Research & Therapy Vol 8 No 2 Steens et al.Page 2 of 7(page number not for citation purposes)associations with...
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Báo cáo y học: "Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB" ppsx

... pulmonary arte-rial hypertension in rats [42]. The observed changes inplasma levels of inflammatory markers in SHR were alsoaccompanied by similar alterations in the left ventriclemRNA expression ... inflammatory process associated toarterial hypertension.This anti-inflammatory effect of captopril has beenpreviously proved in other diseases characterized by an increase in the inflammation process, ... these cytokines. These results are inagreement with previous studies showing that cardiachypertrophy is associated with an inflammatory processin the myocardium of SHR [7,16] and other models...
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Báo cáo y học: " Ethyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse model" ppsx

... by densitometry.Statistical AnalysisData are presented as mean ± SEM unless otherwise indi-cated. Differences between treatment groups were deter-mined by Student&apos ;s t test or 1-way analysis of ... by log-rank test, respectively; survival at 48 h versus survival in vehicle-treated controls; P = 0.75 by log-rank test).Respiratory Research 2009, 10:91 http://respiratory-research.com/content/10/1/91Page ... citation purposes)Respiratory ResearchOpen AccessResearchEthyl pyruvate reduces mortality in an endotoxin-induced severe acute lung injury mouse modelGuan-Hong Shang*1, Dian-Jie Lin2,...
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Báo cáo y học: " Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism" pptx

... Bateman, Greg Haljan, Ehsan Y Davani, Yinjin Wang and Keith R WalleyUniversity of British Columbia Critical Care Research Laboratories, St. Paul&apos ;s Hospital, 1081 Burrard Street, Vancouver, ... inflamma-tory biomarkers such as C-reactive protein and D-dimer areassociated with an increased incidence of, and worse progno-sis for, cardiovascular disease [4-8]. However, whether thesemolecules ... are simply markers of the inflammatory process ormight actually play a causative role in the resultant organ dys-function is not known. We previously reported a novel two-step regulatory mechanism...
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Báo cáo y học: "Comparison between data obtained through real-time data capture by SMS and a retrospective telephone interview" ppsx

... automatically transferred to an electronic data file that can be accessed directly foranalysis. Such a system, the SMS-T-Q [9], was used in aresearch project that formed the basis to the currentstudy.AimsThis ... billion SMS weresent globally, which is 6 SMS per Dane per day [8]. Thistechnology makes it possible to deliver a short messagedirectly to nearly every person regardless of time, place orsetting.Requirements ... to directly identify non-responders and recognize misunderstandings. Non-responders can therefore be contacted to rectify any mis-understandings and improve compliance. The advantagesare that...
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Báo cáo y học: "Pulmonary vascular permeability changes in an ovine model of methicillin-resistant Staphylococcus aureus sepsis" ppsx

... control and methicillin-resistant Staphylococcus aureus (MRSA) sepsis groupsExcessive nitric oxide production and PAR measured in control and methicillin-resistant Staphylococcus aureus (MRSA) sepsis ... inspiratory oxygen; MPAP = mean pulmonary artery pressure; PaO2 = partial arterial pressure of oxygen; Pc = pulmonary capillary pressure; PL-tot = total lung lymph protein; Qs/Qt = pulmonary ... approved the final manuscript.AcknowledgementsThis study was supported by the Shriners of North America grants 8630, 8954 and 8450. The authors thank Professor Moreillon, Univer-sity of Lausanne,...
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