genes involved in the metastatic cascade of medullary thyroid tumours
Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf
... implicated in the biosynthesis of the aminonucleoside moiety of A201A Here we report the sequencing of a total of 6946 bp, which include the ata genes most likely implicated in the biosynthesis of this ... pertain to it Further sequencing of the ata cluster could provide an insight into the biosynthetic pathway of the other moieties of A201A and provide probes which may be useful to identify genes of ... putative genes that are known or proposed to be implicated in the biosynthesis of the aminonucleoside moiety of puromycin [6–8] Interestingly, their organization is identical to that of the pur...
- 9
- 728
- 0
Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf
... The fa value for KI was only 12% implying the low solvent accessibility of tryptophan residues of d2-crystallin in the native form ANS binding Fig Equilibrium unfolding of duck d-crystallin in ... the formation of dimers during the dissociation step (Fig 1) These results are in agreement with the double dimer structure of the tetrameric d2-crystallin The crystal structure of the protein ... is the dynamic quenching constant and fa was the fractional maximum accessible protein fluorescence ANS binding assay The exposed hydrophobic surfaces of the protein were assayed by incubating the...
- 8
- 426
- 0
Báo cáo khoa học: Identification of domains involved in the allosteric regulation of cytosolic Arabidopsis thaliana NADP-malic enzymes ppt
... than the other compounds (Fig 6) In this way, amino acid residues of different segments of NADP-ME2 swapped in the construction of the chimeras are involved in the fumarate activation of the pyruvate ... of CoA or acetyl-CoA The results are presented as the percentage of activity in the presence of the effectors in relation to the activity measured in the absence of the metabolites for each of ... activity in the presence of the effectors in relation to the activity measured in the absence of the metabolites, for each of the respective enzyme constructs The assays were performed at least in...
- 13
- 360
- 0
Báo cáo khoa học: Myocyte enhancer factor 2B is involved in the inducible expression of NOX1⁄ NADPH oxidase, a vascular superoxide-producing enzyme ppt
... structure of the NOX1 gene and its splicing pathway Open boxes indicate exons Numbers in the box denote the size of each exon (bp) The size of the intron is indicated under the broken lines (bp) ... be involved in an angiotensin II-induced vascular hypertrophy [15], and in inducing the expression of monocyte chemoattractant protein-1 [16], which plays a key role in the development of atherosclerosis ... in the promoter region of the NOX1 gene, ATF-1 was assumed to indirectly regulate the expression of the NOX1 mRNA We therefore elucidated the role of ATF-1 in the MEF2B-dependent activation of...
- 9
- 452
- 0
Báo cáo khóa học: Cloning and expression of murine enzymes involved in the salvage pathway of GDP-L-fucose ppt
... variants of the murine fucokinase genes were expressed in COS-7 cells in frame with a 10-amino acid E2Tag present in the pQM vector The molecular masses of fucokinase proteins were determined by ... [23] In the present study we have cloned the murine genes coding for the enzymes involved in the salvage pathway of GDP-L-fucose L-fucokinase and GDP-L-fucose pyrophosphorylase were expressed in ... amino acid sequence of mouse L-fucokinase The predicted amino acid sequence for the coding area of the long splice variant of fucokinase consists of 1090 amino acids Due to alternative splicing,...
- 9
- 437
- 0
Báo cáo khoa học: Determination of the metal ion dependence and substrate specificity of a hydratase involved in the degradation pathway of biphenyl/chlorobiphenyl pot
... chlorine and methyl functional groups at the 5-position Together, these results provide insight regarding the mechanism, the substrate binding site and the role of the metal cofactor in the enzyme ... method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72, 248–254 Laemmli UK (1970) Cleavage of structural proteins during the assembly ... rather than just a substrate binding role Possible roles of the cation include the activation of water for the hydration reaction and ⁄ or the stabilization of the anion transition state In the...
- 9
- 461
- 0
Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc
... and eG19L strains were incubated in the presence or absence of CuCl2 The control experiment (in the absence of CuCl2) was performed in the presence of NEM instead of CuCl2 Cross-linking conditions ... were incubated in the presence or absence of CuCl2 as described in the experimental procedure The control experiment (in the absence of CuCl2) was performed in the presence of NEM instead of CuCl2 ... helix–helix packing interface involving the aminoacid residues on both sides of the insertion [40] In the other two mutants, the small amino-acid residues Gly15 and Gly19 were replaced by leucine residues...
- 10
- 550
- 0
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... receptor-4-induced immune responses [112], indicating the complexity of interactions in the immune response The possible interactions of immune effector cells in the inflammatory phase of the arthritic ... continue within the joint it may drive the disease to the chronic stage, with complete distruption of joint architecture Thus, dissecting the fine specificity of the molecules taking part in the ... yet clear, however, whether the induction of arthritis is due to the binding of citrullinated epitopes or cross-reactivity to other epitopes within the joints The importance of Ig glycosylation...
- 11
- 457
- 0
Báo cáo khoa học: Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways ppt
... devoid of a given essential amino acid Our data suggest that the GCN2 pathway is directly involved in the regulation of amino acid and protein metabolism, as many of the genes involved in these ... contribute to these multistep processes, including the metabolic conditions of the cell, nature of the stimulus, RNA binding factors and the sequence of the target mRNA [35] Another amino acid sensing ... (indicated in bold) The enrichment for a given GO category was computed as the ratio of the distribution of the amino acid-regulated genes* versus the distribution of the genes spotted onto the...
- 12
- 560
- 0
Báo cáo y học: " Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency" docx
... treatment of latently infected cell lines, we observed an upregulation of genes involved in vesicular transport of protein like syntaxin and nexin It was found by Chun et al that numerous genes involved ... represses the IRF1-mediated activation of the HIV-1 ISRE element Implication of IRF8 in the maintenance and NCoA3 in the reactivation of the viral latency may thus provide new insights into the control ... this study, the role of the HDAC inhibitor NaB on HIV-1 latently infected cells gene expression was explored using microarrays Since chromatin remodeling is involved in the regulation of HIV-1 gene...
- 14
- 315
- 0
Báo cáo y học: "Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity" potx
... reproduction in the remainder of the tested genes (Table 5) Early response Protein interaction analysis reveals a novel pathway involved in the response to cadmium In order to further define the molecular ... approximately 21% of the 237 cadmium-inducible genes (≤1.5-fold) are involved in the resistance to cadmium toxicity (although these genes certainly could also be involved in detoxification of other stressors) ... enzyme involved in the biosynthesis of retinoic acid Cadmium has been shown to act synergistically with retinoic acid in the induction of limb-bud malformation in mice [51] The Y46G5A.24 network includes...
- 15
- 336
- 0
Báo cáo y học: "The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing" doc
... structure, and pink indicating the domain that binds Sm proteins The corresponding interaction region in U6atac snRNA is also marked in green Red background indicates G-T base-pairs in the stem-loop ... lacks an SMN protein complex In human, the SMN protein (survival of motor neurons) can interact with a series of proteins including Gemin2, Gemin3 (a helicase), Gemin4, Gemin5 and Gemin6 to form an ... could be involved in splicing of other genes Other human hnRNPs related to splicing also have homologs in Arabidopsis BLAST searches of the human (CUG)n triplet repeat RNA-binding protein (CUG-BP)...
- 23
- 294
- 0
the regulation of genes involved in trichome development
... preferentially with the bHLH dimer, preventing expression of genes involved in trichome development TTG would act in the cytoplasm most probably aiding in the association of the bHLH dimer 13 enters the nucleus ... finding the components of the initiation and inhibitory elements, but also in uncovering how these elements interact Based upon data found in Arabidopsis and other species, a model of the interaction ... Generation of the Trichome Spacing Pattern The mechanism responsible for generating the spacing pattern on the surface of first true leaves has been intensely investigated during the past decade (Larkin...
- 186
- 167
- 0
the regulation of genes involved in trichome development(fileminimizer)
... preferentially with the bHLH dimer, preventing expression of genes involved in trichome development TTG would act in the cytoplasm most probably aiding in the association of the bHLH dimer 13 enters the nucleus ... finding the components of the initiation and inhibitory elements, but also in uncovering how these elements interact Based upon data found in Arabidopsis and other species, a model of the interaction ... Generation of the Trichome Spacing Pattern The mechanism responsible for generating the spacing pattern on the surface of first true leaves has been intensely investigated during the past decade (Larkin...
- 186
- 210
- 0
Effects of high glucose concentrations on the expression of genes involved in proliferation and cell fate specification of mouse embryonic neural stem cells
... 1989) The bending of the neural plate involves the formation of hinge regions The cells at the midline of the neural plate are called the medial hinge point (MHP) cells which are connected with the ... 1987) There are seven members in the Hes family While it is likely that many of these genes are involved in 15 Chapter 1: Introduction the timing of differentiation in a variety of tissues, two of ... of improvement in the management of diabetic pregnancies in the past decades, congenital malformations including NTDs in infants of diabetic mothers remain two to three times higher than in the...
- 257
- 293
- 0
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... of ethanol (100 mM) induced the expression of genes involved in the metabolism of ethanol [16] In addition, the metabolism of ethanol 33 results in an increased production of toxic metabolites ... and the S6b ATPase subunit of the regulatory component of the proteasome Based on the conserved gene expression profile in confluent HepG2 cells in vitro [21], the regulation of genes involved in ... chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut...
- 8
- 702
- 0
Risks Involved in the Use of Herbal Products
... from their ability to inhibit phase I and induce phase II carcinogen metabolizing enzymes that initiate carcinogenesis They also inhibit the promotion stage of carcinogenesis by inhibiting oxygen ... aspirin or other NSAIDs may increase the risk of bleeding Ginseng may intensify the effects of these drugs, causing an excessive decrease in blood sugar levels (hypoglycemia) Ginseng may intensify ... making it less effective Ginger taken with anticoagulants may increase the risk of bleeding Ginkgo taken with anticoagulants or with aspirin or other NSAIDs may increase the risk of bleeding Ginkgo...
- 15
- 396
- 0
Tài liệu Báo cáo khoa học: Involvement of two positively charged residues of Chlamydomonas reinhardtii glyceraldehyde-3-phosphate dehydrogenase in the assembly process of a bi-enzyme complex involved in CO2 assimilation doc
... for the binding of CP12 The presence of this region at the interface of GAPDH and CP12 could also explain the kinetic changes observed for the binding of the substrate when the wild-type recombinant ... partners of this complex These mutageneses are a rst step toward the understanding of proteinprotein interactions in the GAPDHCP12PRK complex and the nature of the physico-chemical forces involved in ... molecular modelling of all mutant GAPDHs indicate no changes of the global structure of the mutants To test whether the interactions of these mutants with the other partners of the GAPDHCP12PRK...
- 8
- 494
- 0
Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... responsible for binding and proper orientation of the aminopyrimidine ring, are conserved in all ThDP-dependent enzymes One of these, the hydrogen bond between the N1¢ atom of the pyrimidine ring of ThDP ... structure Binding of the cofactors ThDP and Mg2+ The homo-tetrameric IPDC binds four molecules of the cofactors ThDP and Mg2+ The ThDP binding sites are located in narrow clefts at the interfaces ... to these interfaces is located in the PYR and middle domains The interface contains 10 hydrogen bonds in IPDC The dimer–dimer interface in IPDC is smaller than the corresponding interface in...
- 10
- 557
- 0
Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... listed in Table that most, if not all, of the amylose is synthesized in vivo when the rate of amylopectin synthesis becomes minimal At these moments the rates of amylopectin synthesis are only 5% of ... rate of amylopectin synthesis The increase in crystallinity witnessed during these first 12 h is in line with the high rates observed for amylopectin synthesis However between 12 and 58 h the rate ... amylose continues to accumulate at the final stage of starch synthesis in the absence of concomitant amylopectin synthesis (reviewed in [41]) In vitro synthesis of amylose Because in Chlamydomonas...
- 11
- 556
- 0
- indian tribes involved in the trail of tears
- native american tribes involved in the trail of tears
- which native american tribe was involved in the trail of tears
- what indian tribe was involved in the trail of tears
- which indian nation was involved in the trail of tears
- what indian tribes were involved in the trail of tears
- what native american tribe was involved in the trail of tears
- calcitonin expression in the metastatic tissue of medullary thyroid carcinoma
- are epigenetic factors involved in the normal expression of neuronal phenotypes during spinal development
- mechanism s involved in the deleterious effect of salt
- identification of genes involved in tumor like properties of embryonic stem cells pdf
- the search for major genes and the role of genes involved in androgen action
- genes involved in the secretion and action of insulin
- epidermal growth factor receptor pathway activation of egfr by its ligands such as egf initiates signalling cascades that regulate the transcription of genes involved in survival proliferation and invasion
- bioinformatics search of atox1 consensus sequences and response elements in the promoter of genes involved in dna damage response and antioxidant defense
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25