the search for major genes and the role of genes involved in androgen action
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered Vol 45 / No RR-4 MMWR and the vaccinee’s age at the time of vaccination ... RR-4 MMWR The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory ... re-evaluation of the role of BCG vaccination in the prevention and control of TB in the United States CDC, the Advisory Council for the Elimination of Tuberculosis (ACET), and the Advisory Committee...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... side-chains are important for the GABA transport activity 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into the role of the terminal structures of the N-glycans ... N-glycans is involved in the regulation of the stability and trafficking of GAT1 It has been reported that a variety of molecular chaperones and folding enzymes assist the folding of newly synthesized ... misfolding of this protein, resulting in its partial retention in the ER and its rapid digestion thereafter [16,19] Accordingly, our results indicate that the intracellular trafficking of N-glycosylation...
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Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... Survey In 1996, the credit has overall been decreasing for 53% of the sample, it has been increasing for 36%, and has been stable for the remaining 11% An increase in indebtedness (of 80% in average) ... part of the research THE DISTRIBUTION OF THE FIRMS PERFORMANCES : REAL PERFOR-MANCES AND FINANCIAL CONSTRAINTS In this section we analyze the probability that firms declare making profit or being ... the left to the right-hand side of the map decreases the probability of Expected-Debt to be equal to ô ằ (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... except for the position of residue 142 [34] The pKa calculations indicate that the only candidate for a residue determining the basic arm of the pH-activity profile of the D142N mutant is Glu144 The ... constant of eight was used for the protein [39] A significant speed-up of the calculations was achieved by calculating pKa values for only a subset of the titratable groups in the protein The subset of ... in the ÔupÕ position rows and shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pKa of the latter by 0.8 pH units The calculated effects of the D140N and...
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Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf
... contribute to the binding of the substrate by hydrogen bonding and ⁄ or hydrophobic interactions Using the ligplot program [31], we investigated the specific interactions between enzymes and each NAG ... orientations of the Glu526 side-chain in the A-form were almost identical, and the maximum coordinate shift ˚ after superimposition of the two structures was 0.78 A In the B-form, in contrast, the Glu526 ... decrease in activity [39] On the other hand, in ‘planttype’ chitinases (AD2, hevamine and ScCTS1), the side-chain of the D2 residue always faces towards the catalytic Glu whether the substrate binds...
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Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
... using the concentration of protein in the extract as an internal standard The activity of ()119/+178) PS1CAT in the presence of the empty vector was taken as 100% The values represented in the ... ER81 and PEA3), ER81 and ERM being the most related [35] PEA3 members all contain the highly conserved ETS domain ERM contains two DNA binding inhibitory domains flanking the Ets domain: the central ... (d) and Sp1 (h) motifs in the )119/+178 region of the PS1 promoter are indicated The positions relative to the +1 site of point mutations (X) eliminating Ets or Sp1 consensus in each motif are indicated...
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Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx
... loss of penicillin binding Arginines 306 and 307 Fig Proposed binding mode for penicillin N to the iron(II)-2-oxoglutarate complex of DAOCS, showing possible involvement of selected residues The ... The third type of mutant, represented by arginines 306 and 307, are located in the C-terminus They appear to modulate the activity of the C-terminus, which encloses the DAOCS active site during ... effect on the kcat value Note the increased specific activity for the R306L mutant may reflect a decreased rate of inactivation for this mutant binding to the enzyme (arginines 160, 162 and 266),...
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Báo cáo khoa học: The role of residue Thr249 in modulating the catalytic efficiency and substrate specificity of catechol-2,3-dioxygenase from Pseudomonas stutzeri OX1 ppt
... chain and the groups of the substrate directly involved in the reaction An analysis of the active sites of DHBD structures in the presence and in the absence of substrates and of the structure of ... two residues and the edge of the substrate ring could prevent binding of 3,6-DMC and 3,5-DMC, as shown in Fig 2D,E,F Thus, the binding of 3,5-DMC and 3,6-DMC to the active site of C2,3O could ... 3,6-DMC Interestingly, the progressive decrease of the dimension of the residue 249 side chain also causes an increase in the Km values for catechol and 3-MC (Fig 4A) In the case of the smaller...
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The role of international agreements in environmental conservation and its implication to Vietnam
... further examined with the relevant economic theories which are introduced in the Chapter of the thesis By applying economic theories, the roles and mechanisms of international agreements in conservation ... game theories New findings out of the thesis This thesis presents the following new findings (1) New findings related to theory (a) A new economic equation to relate two levels of sustainable ... agreements mathematically in terms of environmental conservation The proposed thesis is, therefore, unique, original and very challenging in this aspect The followings are some of the important...
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regional business cycle and real estate cycle analysis and the role of federal governments in regional stability
... dominant states play quite a signi cant role in the formation of the business cycle patterns of the formar group of states The business cycle patterns of the major oil supply states are distinctly ... (2.15) Rather than using only the previous information, it is possible to obtain the probability of the economy being in either recession or expansion Pr[St = j j using the full set of information ... dominant states' geographic proximity from the economically dominant states plays quite a signi cant role in the formation of the business cycle patterns of the former group of states The business...
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báo cáo hóa học: " Discrimination and reliability: equal partners? Understanding the role of discriminative instruments in HRQoL research: can Ferguson''''s Delta help? A response" pptx
... remains to be seen how these elements, particularly reliability and discrimination, interact In closing I should directly answer the questions posed by Norman and Wyrwich in the titles of their ... 'Discrimination and reliability: Equal partners?' to which the answer is no; reliability trumps discrimination, for reasons explained above Wyrwich asks 'Understanding the Role of Discriminative Instruments ... points, then a discrimination is defined as any between-persons difference > = points Delta then indexes the degree to which the instrument makes valid discriminations Wyrwich suggests that the...
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báo cáo hóa học:" The role of tendon microcirculation in Achilles and patellar tendinopathy" doc
... either AirHeel™ wrap or eccentric training or the combination of both [57] Non-invasive topical nitroglycerin in tendinopathy The rationale for the use of topical transdermal nitroglycerin in ... Sclerosing with polidocanol was performed in the area of neovascularisation resulting in an improved knee function and reduced pain in the polidocanol group in contrast to the lidocaine/epinephrine ... or in tendinopathies at the wrist level The diagnosis of tendinopathy of the main body of the Achilles tendon is made if patients have Achilles tendon pain at rest or at exercise in the main...
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Báo cáo khoa học: "Experimental reproduction of proliferative enteropathy and the role of IFN-gamma in protective immunity against Lawsonia intracellularis in mice" pdf
... ylevitcepser ,puorg lortnoc a rof dna puorg noitcefni na rof dengissa erew ecim eerhT esuom detcefnifo noloc dna mucec cimerepyh dna degralne )D( dna ,esuom detcefninu na fo enitsetni lamron )C( ... ytlucaF eht yb detroppus saw krow sihT stnemgdelwonkcA snoitcefni tsniaga ytinummi evitcetorp a fo noitcudni eht rof γ-NFI fo ecnatropmi eht deilpmi stluser esehT enitsetni egral eht ni snoisel ... noswaL ,S tsirOcM ,S insaJ 761-951 ,601 ,2991 htaP pmoC J sitiretne evitarefilorp enicrop fo noitcudorper latnemirepxE JP eoloC ,R dnalroB ,RM notredlA secnerefeR 4002 ni ytisrevinU kuknoK fo dnuF...
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Báo cáo y học: "α The role of HIF-1α in maintaining cartilage homeostasis and during the pathogenesis of osteoarthritis" pot
... the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional inactivation of HIF-1α in the presence of interleukin-1β ... Thus, the work by Yudoh and colleagues adds further experimental evidence for the suggested role of HIF-1 in protecting chondrocytes from cell death induced by pro-inflammatory cytokines Finally, ... is of pivotal importance in cartilage development and homeostasis Furthermore, given the decreased oxygen levels and presence of inflammatory mediators during the course of OA, a causal role for...
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Báo cáo y học: "The role of transposable elements in the evolution of non-mammalian vertebrates and invertebrates" doc
... (total of 98,695 introns) for TE insertions to determine the percentage of TE-containing introns (Figure 2a) The fraction of the introns that contain TEs in the non-mammalian vertebrates G gallus and ... between the fraction of introns containing TEs and median length of introns (Figure 2c), implying that TE insertions have played a role in the evolution of intron size Previous analysis of human and ... targets for microRNA binding, or even result in precursors for new microRNAs [46,47,53] Presumably, the increase in the size of the last exons and in the percentage of TEs within these exons from invertebrates...
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Báo cáo y học: "The role of a pseudocapsula in thymic epithelial tumors: outcome and correlation with established prognostic parameters. Results of a 20-year single centre retrospective analysis" pptx
... combined treatment, and in another patient an immunotherapy was performed Adjuvant radiation was executed in 26 cases, chemotherapy alone was given in cases, and a combination of both was performed ... [3] The reason for these is based in a couple of problems First, there is a significant interobserver variability in histological typing [2,6] Second, determination of precise cut-off points ... difference in survival was determined by using the log-rank test and in case of significance a univariate analysis and Cox-regression analysis was carried out Results Pathological and Clinical Findings...
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Báo cáo y học: " The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer" ppsx
... spectra of pro-vitamin D and their photoproducts overlap with the absorption maxima of DNA, RNA, and proteins [20] Role of VitD in bone metabolism VitD, which is photosynthesized in the skin or ... modulate the inflammatory profile after a viral infection by blocking the poly(I: C) induced chemokine and cytokine production while maintaining the antiviral activity [28,59] As epithelial cells ... the review, all authors contributed in writing and reviewing the paper All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests...
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Báo cáo y học: " The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice" pps
... trophic for the epithelium and potentially could influence the regenerative response of the epithelium to chlorine [12] To evaluate the role of γδ T cells in chlorine induced airway injury we ... subjects The factors influencing the rate of epithelial regeneration are likely of key importance in determining the short and long term consequences of chlorine induced airway dysfunction The γδ ... since the inflammatory response to epithelial damage was also attenuated in the γδ T cell deficient mice Our findings are consistent with a role of γδ T cells in determining the magnitude of the...
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Báo cáo y học: " Th2 cytokines and asthma The role of interleukin-5 in allergic eosinophilic disease" doc
... except for short stretches in the murine interleukin-3, murine GM-CSF, and murine interferon-γ proteins [25] Furthermore, in the interleukin-5 promoter region there are short stretches of conserved ... autocrine production of interleukin-5 may contribute to the chronicity of inflammation [41,42] The interleukin-5 receptor is in the type I cytokine family, which includes receptors for interleukin-2 ... antibodies to interleukin-5 are given before the antigen challenge [75] There is also increased expression of mRNA for Th2 cytokines such as interleukin-5 and interleukin-4 in the lungs of allergic...
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Tìm thêm: khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25