Điều trị tăng huyết áp yếu tố nguy cơ cao PGS châu ngọc hoa

ĐIỀU TRỊ TĂNG HUYẾT ÁP YẾU TỐ NGUY CƠ CAO CẬP NHẬT TỪ CÁC KHUYẾN CÁO PGS.. Prevalence of raised blood pressure World Health Organization 2011, Map Production: Public Health Information

ĐIỀU TRỊ TĂNG HUYẾT ÁP YẾU TỐ NGUY CƠ CAO

CẬP NHẬT TỪ CÁC KHUYẾN CÁO

PGS TS BS CHÂU NGỌC HOA

ĐHYD – TP HCM

Prevalence of raised blood pressure

World Health Organization 2011, Map Production: Public Health Information and Geographic Information Systems (GIS)

The NHLBI Division for the Application

of Research Discoveries (DARD):

Translating Science into Practice

Karen A Donato, S.M

Acting Deputy Director, Division for the Application of

Research Discoveries National Heart, Lung, and Blood Institute

July 8, 2011 Filippino Cardiovascular Summit

Hypertension Treatment Options

2013 ESH / ESC Hypertension Guidelines

HOT VALUE

STOP-2 UKPDS

LIFE RENAAL IDNT IRMA ABCD

1 2 3 4

ASCOT-BPLA (136.9 mmHg)

ALLHAT (138 mmHg) IDNT (138 mmHg) RENAAL (141 mmHg)

UKPDS (144 mmHg) ABCD (132 mmHg)

MDRD (132 mmHg) HOT (138 mmHg)

AASK (128 mmHg)

ACCOMPLISH (132 mmHg)

Average Nr of Antihypertensive Drugs

Study (syst BP achieved)

Number of antihypertensive drugs in

intervention studies

 1/3 normalized with 1 agent

 1/3 normalized with 2 agents

 1/3 normalized with ≥3 agents*

Düsing, Vasc Health Risk Manag 6: 1, 2010

*32,3% in ACCOMPLISH

Antihypertensive combinations: what do the guidelines tell us?

;

Hypertension Treatment Options

2013 ESH / ESC Hypertension Guidelines

Na+-loss and volume

RAS-blocker

RAS-blocker + diuretic

RAS-blocker + CCB

RAS-blocker

RAS-blocker + diuretic

RAS-blocker + CCB

RAS-blocker + diuretic + CCB

Step 1

Step 2

Step 3

Treatment algorithm

Phối hợp điều trị - Phòng biến cố tim mạch

29

Edward D Freis, MD

We are not treating numbers, we are treating patients!