... Drosophila MAD and the vertebrate Smad1,Fig. 1. Structure of the SmSmad1B gene, cDNA and protein. (A) Schematic representations of the SmSmad1B gene, cDNA and protein and the amino acid sequence of SmSmad1B ... Fantappie2,Francisco M. B. Oliveira2 and Philip T. LoVerde1,21 Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, State University of New York, NY, USA2 Southwest ... The presence of a histidine and an aspartate at positions 340 and 343within the L3 loop of SmSmad1B (Fig. 1A) is highlyconserved among R-Smads that transduce BMP-likesignals, and, as expected,...