Báo cáo khoa học: ERK and cell death: ERK location and T cell selection pdf
Báo cáo khoa học: Oligomannose-coated liposomes efficiently induce human T-cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant doc
... prevent the relapse of ATL inpostallogeneic stem cell transplantation patients.The expression of Tax by the host cell targets themfor attack by CTL, resulting in the elimination of theinfected ... unpulsed T2 -A2 cells as target cells,specific cytotoxic activity was evaluated by FCM assay of cell- mediated cytotoxicity. All tests were carried out in triplicate at effector : targetratios of ... [34,35]. The CD8 cell- dependent CTLs alsoappear to directly target the Tax protein because whenthe histone deacetylase inhibitor, valproate, is used toactivate tax transcription, the HTLV-1 proviral...
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Báo cáo khoa học: Plant oxylipins: role of jasmonic acid during programmed cell death, defence and leaf senescence doc
... downstream elements that ultimatelyconverge at the EXECUTER1 and EXECUTER2 genes. Most of the intermediates in this pathway have not yet been identified and are there-fore highlighted with a ... hypersensitiveresponse-like cell death symptoms [92]. Taken together,these results emphasize that signals other than SA, JA and ethylene must be involved in the regulation of cell death in cet plants ... permeability transition, release of cyto-chrome c and caspase activation. In plants, a plastid-derived pathway of cell death regulation exists that comprises singlet oxygen and JAthat activates specific...
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Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... sense,5¢-CCGAGATCTGGCTTTTACTTAAACCG-3¢; IL6Rantisense, 5¢-CAGGAATTCACTTGCTCTGTCACCC-3¢;GAPDH sense, 5¢-GCGAATTCCGTGTCCCCACTGCCAACGTGTC-3¢; GAPDH antisense, 5¢-GCTACTCGAGTTACTCCTTGGAGGCCATGTGG-3¢. The ... expressed as the means ± standard devia-tion (SD) and statistical analysis utilized a two-tailed Stu-dent’s t- test. Statistical significance was set at P £ 0.05.AcknowledgementsWe thank the Tumor ... miR-23a promotes growth activityof MGC803 cells. MGC803 cells weretransfected with miR-23a ASO or pri-23avector, and cell growth activity wasdetected through the MTT (A) and colonyformation (B)...
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Tài liệu Báo cáo khoa học: Inhibition of pneumococcal choline-binding proteins and cell growth by esters of bicyclic amines pptx
... exert their toxic effect through other targets inaddition to, or instead of, the CBPs; this deserves fur-ther and thorough investigation.Despite their structural similarity, atropine and ipratropium ... elution process, indica-ting that N-substitution is a minor determinant in theprotein–ligand interaction, provided that the substitu-ent is hydrophobic [26]. On the other hand, when test-ing ... 1B). These results reinforce the hypothesis thatatropine and ipratropium are bound to tryptophan-containing sites through different binding interactions.It should be pointed out that the fluorescence...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
... activation, and both required toensure plasmin anchorage and subsequent proteolyticactivity. These structural and functional transitionsare determinant in the initiation and acceleration offibrinolysis ... anchorage and functioning. BothK1- and K4-LBS support Lys-plasmin(ogen) binding and activation. These structural–functional transitionsare determinant in the initiation and development ofboth fibrinolysis ... conformations and LBS accessibility toits functional properties such as binding to fibrin and cells, activation on these surfaces and the effect ofplasmin proteolytic activity on fibrinolysis and extra-cellular...
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Báo cáo khoa học: Linking pseudouridine synthases to growth, development and cell competition potx
... compartment (Fig. 7).This indicated that the silenced cells, albeit retaining Didentity, failed to maintain stable interactions withother D cells and sorted-out towards the V compart-ment. This ... relatedto its human counterpart, sharing with it 66% identity and 79% similarity. The conservation increasesremarkably within several specific domains, so thattotal identity exists between the ... 3H). Taken together, these results indicated thatloss of Mfl can affect both cell size and number. Therelative contribution of these effects to wing size maydepend on the strength of the GAL4...
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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf
... thereticulum of endothelial cells [32]. Thus, it is likelythat epithelial, mesangial and endothelial cells can allcontribute to renal cholinesterase activity, but themost important point is the comparable ... acetylcholinesterase mRNAs, their lifespan and translational efficiency, and the capacity of thetranslated product to bind to protein partners.The upregulation of butyrylcholinesterase in pRCC(Table 1 and ... regarding the higher acetylch-olinesterase activity in kidney tumours suggest that arelationship may exist between increased acetylcholin-esterase activity and cell proliferation, a link that hasalso...
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Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt
... present and activ-ated in the system. Another could be that the intracellu-lar concentrations of ATP (Mg) are high enough toattenuate observed inhibition. Alternatively, it may wellbe the case ... in the presence and absence of ATP. Kappmis the apparent dissociation constant for fulllength GST-IjBa substrate at saturation concentration of 60 lMATP, and the dissociation constant for ... 10)3lM.(B) The control rhIKK2 in vitro kinase assay with no GST-IjBa substrate. The time (in minutes) on the abscissa indicates the time the reac-tions were stopped with trichloroacetic acid and the...
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Báo cáo khoa học: Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells pot
... activator system plays a central rolein wound healing, inflammatory and tissue dissolution, and cell invasion and metastasis. Tumor cells need topenetrate the extracellular matrix (ECM) and the ... 5¢-GTCACCACAGGCTAGCTACAACGACCAGGCACT-3¢Dz483 (mutant) 5¢-ACACCACTGGGCTAGCTACAACGATCACGGACC-3¢ 483 ntDz720 (active) 5¢-GAGCATCCAGGCTAGCTACAACGAGGGTGCTGT-3¢Dz720 (mutant) 5¢-TAGAGCCACGGCTAGCTACAACGATTGGCGTGG-3¢ ... than that of the cor-responding mutant control after the third Dz720transfection for 24 h using the same transfectionmethod as in Fig. 4 (data not shown). This resultshows that two more transfections...
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Báo cáo khoa học: AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death ppt
... proteins into an active form and in thedegradation of regulatory proteins that prevent PCD.Thus, cysteine proteases that interact with cystatin maybe good candidates for activities that execute ... cystatin A (stefin A) inthe binding of target proteinases: characterization by kinetic and equilibrium methods of the interactions of cystatin A Gly-4mutants with papain, cathepsin B, and cathepsin ... plantsoverexpressing AtCYS1 provides the evidence that NO isnot cytotoxic for the plant, indicating that NO functionsas cell death trigger through the stimulation of an activeprocess, in which cysteine proteases...
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Từ khóa: Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP