Tài liệu Báo cáo Y học: Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II ppt
Tài liệu Báo cáo Y học: Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase pdf
... histidine phosphorylation in eukaryotes has beensparsely studied compared to protein serine/threonine and tyrosine phosphorylation. In an attempt to rectify this by probing porcine liver cytosol with ... resultsprovide a new tool for studying eukaryotic histidine phosphorylation/ dephosphorylation.Keywords: dephosphorylation; N -phosphorylation; phos-phoamidase; phosphopeptide; protein histidine phospha-tase.Boyer ... is the reversibleprotein histidine phosphorylation by protein kinases and phosphatases [3,11]. An important contribution to the latterfield was the purification of a yeast protein histidine kinase in...
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Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf
... similar to that of the type I (single multifunctional enzymes) and type II (multienzymesystems) polyketide synthetases (PKS; data not shown)[33,34]. In contrast, its similarity to type III ... antifungal(blasticidin S, mildiomycin), antiviral (oxetanocin, Ara-A),antitumoral (oxanosine, neplanocin A), herbicidal (poly-oxins), insecticidal (nikkomycins), inmunostimulative and inmunosuppressive ... implicated in thebiosynthesis of the aminonucleoside moiety of puromycin[6–8]. Interestingly, their organization is identical to that of the pur cluster, with the exception of pur6, which is...
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Tài liệu Báo cáo Y học: Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II ppt
... Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II Thierry Dubois1, Preeti Kerai2,*, Michele Learmonth1, Andy Cronshaw1 and Alastair Aitken11The ... fter phosphorylation by C KIa and purification by HPLC. The radioactivity was released inFig. 1. Phosphorylation of centaurin-a1, 14-3-3, syntaxin-1A, and munc18 by CKI, CKII and PKA. Casein kinase ... CKI may play a role insynaptic vesicle exocytosis.Keywords: CKI; CKII; syntaxin-1A; trafficking. Casein kinase I (CKI) belongs to a family of serine/threonine protein kinases with seven isoforms...
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Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx
... separated by SDS/PAGE and immunoblotted with anti-UP12 Ig and anti-GroEL Ig,respectively. Quantification of protein bands was performed by scanning densitometry, as described in Experimental procedures. ... GatY and UP12, respectively. GatY (D-tagatose-1,6-bis-phosphatealdolase of class II) , is a homotetrameric protein consisting of 31-kDa subunits; it belongs to a family of lyases involvedin ... exponentially grown cells by immunoprecipitationwith anti-GroEL Ig [27]. The high yield of the UP12-GroELcomplex isolation and the ATP-mediated dissociation of the complex strongly support the suggestion...
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Tài liệu Báo cáo khoa học: Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein ppt
... DNAs and RNAs.Fig. S3. Binding affinity of EWS and RBD toHtelo.Fig. S4. In vitro arginine methylation of RGG3 by PRMT3.Fig. S5. Identification of significant residues at RGG3for rHtelo binding ... EAD domain therefore inhibited the high-affinityHtelo binding of RGG3 and RBD. The ability of RGG3 and RBD to repress transcription activation by EAD raised the possibility that RGG3 and RBD ... Takanori Oyoshi11 Department of Chemistry, Faculty of Science, Shizuoka University, Japan2 Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Kagawa, Japan3 Division of Gene...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... [54,70]. Inhumans, T-bet gene expression is found to be rapidlyinduced by IFN-c in lymphoid and myeloid cells [71],but not by IFN-a, LPS or IL-1, indicating that theaction of IFN-c is specific. In ... within the microenvironment, which, in turn,influence transcription factors and key signalling path-ways [8]. Th1 differentiation is initiated by coordinatesignalling through the TCR and cytokine ... Th17 differentiation is initiated by TCRsignalling, together with TGF-b1 and IL-6 receptorsignalling, which activates STAT3 and induces theexpression of the transcription factor retinoic acid-related...
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Tài liệu Báo cáo khoa học: Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis doc
... were identified in M. catarrhalis. Theacyloxyacyl-linked secondary acyl chains of the lipid Amoiety of the LOS are important in some biologicalactivities of M. catarrhalis. Elucidation of lipid ... E. coli lipid Abiosynthesis involve the addition of lauroyl and myri-stoyl residues to the distal glucosamine unit, generat-ing acyloxyacyl moieties. The E. colilauroyl and myristoyl transferases ... Modification of lipid Abiosynthesis in Neisseria meningitidis lpxL mutants:influence on lipopolysaccharide structure, toxicity, and adjuvant activity. Infect Immun 69, 5981–5990.39 Schnaitman...
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Tài liệu Báo cáo khoa học: Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf
... anintrinsic histone acetyltransferase activity, which facili-tates transcription by decreasing chromosome conden-sation through histone acetylation and by increasingthe accessibility of the ... domain of SmSmad1B containsa typical C-terminal SSVS phosphorylation motif,which is the site of phosphorylation by type I receptors of the TGFb superfamily (Fig. 1A). The presence of the SSVS phosphorylation ... genome of S. mansoni.As SmTbRI was only capable of binding human TGFbligands in concert with SmTbRII [7], the proposed sec-ond type I receptor may be activated by BMP ligands and may utilize...
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Tài liệu Báo cáo khoa học: Identification, sequencing, and localization of a new carbonic anhydrase transcript from the hydrothermal vent tubeworm Riftia pachyptila docx
... thephylogeny. The present study cannot exclude thatclades I and II could have a common origin withcytosolic CAI, CAII, CAIII, CAVII and mitochondrialCAV vertebrate isoforms, as previously suggested ... in black and grey, respectively. Histidine residues involved inzinc binding in the catalytic site are indicated by a ‘Z’; important amino acids involved in the hydrogen bond network are indicated ... study on specific CAactivity in this latter species. CA activity is however,present in R. pachyptila, and, if these transcriptsencode for functional proteins, a possibility of replace-ment of...
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Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx
... notsignificant. Overexpression of cystatin B, non-seleniumglutathione peroxidase and translation initiation factoreIF-2B transcripts was limited to a relatively shorttime-window at days 14 and ... proteolysis,was strongly expressed, but only in gills. The upregula-tion of CTSL, combined with the downregulation of its reversible binding inhibitor cystatin B, implies thatactive protein degradation ... [43]. In many spe-cies, the increase in lipid peroxidation and reactiveoxygen species concentration in cells following heatstress has already been shown to modify the activity of antioxidant...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếThơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM