Xay dung cong thuc vien nang chua cao diep ca

Trong các loại dược liệu phổ biến, Diếp cá là loại rau ăn quen thuộc hằng ngày được nhân dân ta sử dụng làm thuốc với nhiều tác dụng: trị táo bón, trĩ, mụn nhọt, lở ngứa,….Tuy nhiên có một số bất tiện trong việc sử dụng dược liệu này như khó ăn và không thể ăn với lượng lớn. Mặt khác, việc sử dụng dược liệu như thực phẩm hay các sản phẩm không được chuẩn hóa và kiểm soát chặt chẽ sẽ ảnh hưởng lớn đến tính an toàn và hiệu quả trị liệu. Vì vậy, đề tài nghiên cứu xây dựng công thức viên nang chứa cao Diếp cá được thực hiện với những mục tiêu cụ thể như sau: 1. Xây dựng và thẩm định quy trình định lượng quercetin trong cao Diếp cá và viên nang chứa cao Diếp cá. 2. Xây dựng công thức viên nang chứa cao Diếp cá. 3. Xây dựng tiêu chuẩn kiểm nghiệm cho viên nang bào chế được. Ý nghĩa của đề tài: 1. Góp phần nghiên cứu và cung cấp cơ sở lý luận bào chế các chế phẩm từ cao dược liệu. 2. Là cơ sở cho các nghiên cứu sau này trên quy mô pilot và công nghiệp.

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Q DANH MỤC CÁC KÝ HIỆU VÀ CHỮ VIẾT TẮT )) 3[Hh3=Y=RVYc=H;9k=XW=98 ¢)::V=3^93VV–––3=3^6)^6A93=^6U13:9:£ 6 v 6VFV–VF1  v  )=U9V39F36  Ii=?3l3[9^1 K 9Q?  9Fc49FIJ=Q^?\H K :Q?  9Fc4:^Q^?\H  "<=Oe6Œ43[]4=^V ¢34UF–VF1^=U3X3KFV1^9V4F^HA£ aU aU9^V6 ˜" h6[==š9I+4?W3¢˜U6^93QU"9^K^FKUQ3^93V£ " h6[==š¢"9^K^FKUQ3^93V£ "(a "<=Oe6JH1Œ4 " "W9P9G  F4Z 9 ˜ p343^6I  W=95  54VN3¢69F^3V6U9£  9Q? l9k=9FIJ=Q^?\H  :Q? l9k=:^Q^?\H DANH MỤC CÁC BẢNG F^4 Bảng 2.1.Y=j^=>9M9YKIi=:5Km49FV443g=P/ˆ Bảng 2.2. Y=9389CK | 49FV443g=P/y Bảng 2.3. I+4HYHH^=Y=K4KC==jn4?h9>H+/‹ Q3 Bảng 2.4.Y==@49P=9389O89W3I=@49P=Q3g^4-- Bảng 2.5. C9kQ3g^4=P^=^V38H=Y›4H{P4j^c=-ˆ Bảng 3.1.(89X{O{V:Y99k9I+49k=[9W49Fgy6*93g11L=šv. Bảng 3.2.(89X{O{V:Y99k9I+49k=[9W49Fgy6*93g11L95v. Bảng 3.3. (89X{O{V:Y99k9A89kHI+4HYH?C6Ii4›4vv Bảng 3.4.(89X{O{V:Y9?h=k2Y=HI+4HYH?C6Ii4›4v† Bảng 3.5. (89X{O{V:Y9?h?S4=z^HI+4HYH?C6Ii4›4v† Bảng 3.6. Y==@49P=9389O8?l2Y=?CR16Ii4=^V9k=iHvˆ Bảng 3.7. hš1=Y==@49P=/M-MvM†vˆ Bảng 3.8. Y==@49P=9389O8?l2Y=?CR16Ii49YKIi=S9vˆ Bảng 3.9.hš1=Y==@49P=/M-MvM†vy Bảng 3.10.Y==@49P=9389O89W3Ij^=@49P=Q3g^4vy Bảng 3.11.hš1=Y==@49P=O{V:Y9¢/•/.£v‹ Bảng 3.12. j=={A=Y==@49P=O{V:Y9¢/•/.£v‹ Bảng 3.13.  9Fc43lO38=z^=Y==@49P=O{V:Y9¢/•/.£v‹ Bảng 3.14.;W=TN9=z^=Y==@49P=O{V:Y9¢/•/.£v• Bảng 3.15.hFE=Y==@49P=O{V:Y9¢/•/.£v• Bảng 3.16. (89X{O3l143[1?h?n4?DQDOW36Ii4†. Ba ̉ ng 3.17.(g Ž 9X^ } ?V?@ • F^ f †/ Ba ̉ ng 3.18.(g Ž 9X^ } ?V?@ • ; } 1†/ Bảng 3.19. (89X{?C9kQ3g^4=P^=^V38H=Y†/ Bảng 3.20. (89X{O3l143[1Q3g^438H=Y†y DANH MỤC CÁC HÌNH ẢNH F^4 Hình 1.1.;A38H=Yv Hình 1.2.@49P==>9NV=z^XUF=39F3QR3:VXUF=39F3† Q33 Hình 1.3. "+?n=>9NV=4=z^1h9[9W4/. Hình 1.4.^ Ž =2Y=?C9p343^=89¢9 . £QR9p343^6I¢9 ˜ £// Hình 1.5. Y=2Y=?C:W?b^6e9A89/- Hình 1.6. 8Hš1)FbI+4/v Hình 1.7. 8Hš1U6^–/v Hình 1.8. 8Hš1UK39^/† Hình 2.1.I+4HYH2Y=?C4j=4¤=z^h9MN99W=-† Hình 3.1. "<=Oe?nv1L95wIJ=:j49s-ˆ.1•†ˆ.1-‹ Hình 3.2. "<=Oe?n=V9VF1L95-‹ Hình 3.3. "<=Oe?n=Y=KC=9zAH;XUF=U93:^/M-QRv-• Hình 3.4. "<=Oe?n1L959FIJ=QR:^O36VN39NH›4"09G=8-• Hình 3.5. "<=Oe?n1L=šv/ Hình 3.6. "<=Oe?n1L95v/ Hình 3.7 "<=Oe?n1L9F<4v/ Hình 3.8. "<=Oe?n1LK41@3v- Hình 3.9. "<=Oe?n1LK4K3 • =IJ=^=3KHV:HVF3=.M-¥v- Hình 3.10. (89X{=n4H¦1L=šM1LK41@3M1L9YKIi=QR1LK4 KC=I+ Ž =^=3KHV:HVF3=.M-¥v- Hình 3.11. 3l?n9k9A89k=z^HI+4HYH?C6Ii4›4vv Hình 3.12. 3l?nH;W=+ f N9=z^=Y==@49P=9s/?8ˆv• Hình 3.13. 3l?nH;W=TN9=z^=Y==@49P=9sy?8/.v• Hình 3.14.(89X{?C9k›4"(aQ3g^4=P^=^V38H=Y†/ DANH MỤC CÁC SƠ ĐỒ Sơ đồ 1.1.j19<9XA9FZ:{2>9Q3g^4=P4• Sơ đồ 2.1. j19<9XA9FZ256e1L95/• .  TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NGHIÊN CỨU XÂY DỰNG CÔNG THỨC VIÊN NANG CHỨA CAO DIẾP CÁ Houttuynia cordata   !"#$. K_4=r^1h9:W[=z^Hmr ‹ 1.2. CÔNG NGHỆ BÀO CHẾ VIÊN NANG CỨNG: 1.2.1. Khái quát về thuốc viên nang: [-] 1.2.1.1. Định nghĩa: W=^46RKN49W=W4=P^1h9^A3DVN9=>99FV4QŒ^4