aging of the genome the dual role of dna in life and death mar 2007

The Power of Habit: Why We Do What We Do in Life and Business

... looks at the habits of societies. It recounts how Martin LutherKing, Jr., and the civil rights movement succeeded, in part, by changing the ingrained social habits of Montgomery, Alabama and why ... habitsright.” In the past decade, our understanding of the neurology and psychology of habits and the way patterns work within our lives, societies, and organiza-tions has expanded in ways we couldn’t ... getting drilled in the psychology of habitformation.At boot camp, he had absorbed habits for loading his weapon, fallingasleep in a war zone, maintaining focus amid the chaos of battle, and...

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Báo cáo khoa học: Dual role of Nbs1 in the ataxia telangiectasia mutateddependent DNA damage response ppt

... signaling [23]. Domains similar to the ATM-binding domain of Nbs1 are also found in ATRIP and Ku80 and are required for the interaction of these proteins with the ATM-related kinase, ATR, and the ... activation of the S-phase checkpoint. The Mre11-bind-ing domain is responsible for binding to Mre11 during formation of the Mre11–Rad50–Nbs1 (MRN) complex. The ATM-binding domainat the COOH-terminus ... COOH-terminus (BRCT) domain in itsNH2-terminal region, as well as an Mre11-bindingdomain and an ATM-binding domain in its COOH-terminal region (Fig. 1). FHA and BRCT domains areoften present in...

Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx

... stress signal into the nucleus, a genetic reprogramming occurs that leads, on the one hand, to a decrease in the expression of house-keeping genes and protein synthesis and, on the otherhand, to ... di-amide and t-BOOH. Since then, several Yap1 targetsinvolved in ROS detoxiﬁcation have been identiﬁed,including those involved in the thioredoxin and gluta-thione systems, and other antioxidants ... electro-phile in the absence of oxygen and in this case bindsdirectly to the c-CRD Cys598, Cys620 and Cys629 in amanner independent of the Orp1 pathway [23].Metalloid and metal stress The widespread...

Báo cáo y học: "The Geography of Chronic Obstructive Pulmonary Disease Across Time: California in 1993 and 1999"

... superimposing them over other features, and determining the extent to which there was overlap between the grid and a spatial unit in this instance, the Int. J. Med. Sci. 2007, 4 182degree of ... COPD-related mortality has markedly increased, from the twelfth cause of death in 1990 to its current position as the fourth leading cause of death in the U.S. and world-wide [2, 3, 4]. Approximately ... for the 1999 data and joined them with the U.S. Census Bureau summary files 3 (SF-3) for ZCTAs. One of the benefits of using ZCTAs is that the SF-3 Census 2000 data contain detailed information...

Báo cáo khoa học: Dual role of oxygen during lipoxygenase reactions potx

... evaluations The quality of ﬁtting of the kinetic model to the varioussets of experimental data was determined by the coefﬁcient of determination B being the ratio of the explained variation of the data ... Kinetic modellingFor the derivation of the rate equations it was assumed thatfor the concentrations of the reactants used in the experi-ments, binding of the fatty acid substrate to the ... The other 15% of the total variation in y remains unexplained.Fitting procedureFitting of the kinetic model to the experimental data wasperformed by using a Visual Basic program that combinessolution...

Báo cáo khoa học: Structural studies of the capsular polysaccharide and lipopolysaccharide O-antigen of Aeromonas salmonicida strain 80204-1 produced under in vitro and in vivo growth conditions docx

... about the role of these factors in vivo and their role in furunculosis. The A-layer is believed t o play a crucial role in the bacterial protection against c omplement-mediatedkilling in vitro and ... (GalNAcA-containing trisaccharide repeating unit) (Fig. 4A, inset),based on this ratio about 40% of G alNAcA in both CPS and O-chain p olysaccharides was present in the form of aprimary amine. When the ... lLÆmin)1.An electrospray stainless steel needle (27 g) w as buttedagainst the low dead volume tee and enabled the delivery of the sheath solution t o the end of the capillary column. The separations...

Tài liệu Báo cáo khoa học: Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase d and S6K1 and regulating cell growth docx

... of both isoforms of PDIP46 ⁄ SKAR, including the amino acids of the RNA recognition motif (RRM) also known as the RNA binding domain (Fig. 2) [26].Interaction of the human proteins ER and PDIP46/SKAR ... [23,24]. The L7 cDNA insert was found to consist of 666 bp con-taining the 3¢ end of the POLDIP3 coding sequence(with the stop codon) and coded for 163 amino acidspresent at the C-terminus of both ... disappears and the zygotic transcript and protein are found in asubset of cells expressing DmcycE, which encodescyclin E, and undergoing DNA replication [2]. In Drosophila the severity of the wing...

A review of non-financial incentives for health worker retention in east and southern Africa pot

... included “upgrading of hospital and health traininginstitutions throughout the country to improve the working environment,training capacity of the institutions, welfare of the workers and the ... to the treatment and prevention of HIV and AIDS. The programme provides sustained in- service workplace training, access totraining for involved health workers, clinical and laboratory monitoring,provision ... number of summaries of 'bestpractice' strategies used in some of the countries are presented in the form of boxes in section 3 of this paper. The review was biased in favour of published...

THRIVE the vegan nutrition guide to optimal performance in sports and life pdf

... varying states of rest that are not well understood.Maximizing the quality of rest is key. Removing other forms of stressfrom the body during times of rest will speed the rate of recovery. In ... illness sets in. The body is capable of rising to the occasion in a stressful environment; indeed, the morestress, the better the performance—short term. But when the projectis finished and the stress ... shifts fuel sources. Instead of burning fat as fuel, a stressedperson’s system will burn carbo-hydrate in the form of sugar, and the body begins to store the bodyfat instead of using it for energy....

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