Góp phần nghiên cứu thành phần hóa học rễ cây đinh lăng (polyscias fruticosa (l ) harms)

i - T T , 08 ii Polyscias fruticosa iii ABSTRACT In this project, oleanolic acid is a product isolated from the hydrolysis of the saponins from the roots of Polyscias fruticosa (L.) Harms Conditions of hydrolysis of the saponins were in HCl 10% at the for hours The structure of oleanolic acid were determined and identified based on the results of spectral data H-NMR, 13C-NMR combined with DEPT, iv Polyscias fruticosa (L.) 70o v i ii ABSTRACT iii iv v DANH M U, CH VI T T T vii DANH M NG ix DANH M x DANH M xi xii 1: T NG QUAN I TH C V T 1.2 M T S UV C 2: TH C NGHI M 2.1 THI T B T U 10 vi 2.3 CHI N 12 2.4 TH 14 2.5 L 3: K T QU P CH C 16 18 NH C C H P CH T PF-01 18 NH C C H P CH T PF-02 24 4: K T LU N 27 U THAM KH O 28 PH L C PH vii brs Board (NMR) CHCl3 Chloroform COSY Correlation Spectroscopy CTPT 13 C NMR Carbon (13) Nuclear Magnetic Resonance d Doublet (NMR) dd Doublet of doublets (NMR) DEPT Detortionless Enhancement by Polarization Transfer DMSO Dimethyl Sulfoxide EtOAc Ethyl acetate EtOH Ethanol Proton Nuclear Magnetic Resonance H NMR HMBC Heteronuclear Multiple Bond Coherence HPLC High Performance Liquid Chromatography HSQC Heteronuclear Single Quantum Correlation J Coupling constant (NMR) LC-MS Liquid chromatography m Multiplet (NMR) MeOH Methanol ppm Rf Part per million Retention factor Mass spectrometry 13 C 13 C 13 C- 13 C- H-1 H-1 H-1 Ph -12-1988 2006 -VT ... ph Polyscias fruticosa Polyscias fruticosa gi c bi m ph m p ch c b ng t Nam 1.1 1.1.1 Polyscias fruticosa (L. ) Harms (Araliaceae) Tieghmopanax fruticosus (L. ) R Vig (Rene Viguier), [1],[3] Nothopanax... MeOD) (CDCl3 - CD3OD) H (ppm) C (ppm) C (ppm) -CH2- 1,80; 0,99 (2H, m) 36,8 37,6 -CH2- 1,80; 1,47 (2H, m) 29,2 29,4 -CH< 3,43 (1H, m) 76,9 79,4 -CH2- 38,3 40,1 >C= 140,4 140,7 -CH= 5,32 (1H, s)... D-glucopyranose (CDCl3 - MeOD) (CDCl3 - CD3OD) H (ppm) >CH-O- C 4,22 (1H; d; J= 8,0 Hz) (ppm) C (ppm) 100,8 101,5 >CH-O- 2,90 (1H, m) 73,4 73,9 >CH-O- 3,12 (1H, m) 76,7 76,9 >CH-O- 3,02 (1H, m) 70,1 70,6 >CH-O-