... in the design of the study, acquisition, analysis and interpretation of data and drafting the manuscript BB and BL performed the histological and morphometrical analyses, and contributed to the ... 25 µm and 400 µm respectively This hypothesis is further supported by the data obtained in BLM-treated C57 B1/6J mice in which both emphysema and fibrosis were significantly attenuated by the use ... emphysema and fibrosis may result from two distinct and apparent opposite processes, they may coexist either in different areas, or in a same area of the lung of humans and animals The development and...
... the Polaris mine on Little Cornwallis Island andthe Nanisivik mine on the north coast of Baffin Island – and three former mines in Greenland known to be sources of heavy metals entering the sea ... protection, andthe effectiveness of compliance and enforcement This chapter examines the tensions betweenthe principles of precaution and pollution prevention, on the one hand, and actual practices ... must recommend listing and prepare a draft decision guidance document; andthe Conference of the Parties must approve the listing The Convention’s provisions on technical assistance are also...
... health, H, and leisure Leisure is implicitly defined by the age at retirement a Relative preferences for income and leisure Defined as the ratio of the growth in the present discounted value of the ... Health and Retirement Survey (HRS) The first wave was fielded in the fall of 1993 and consists of 4727 households in whichthe head of the household (i.e., themain income earner) was between 43 and ... quarter of the century in the United States and in the Netherlands, Sweden and Germany This coincides with an increase in both access to andthe generosity of publicly provided social insurance and...
... that the phenotypic differences observed betweenthe mutated andthe wild-type strains relied solely on the disruption of the Rv2951c gene Together, these results established that Rv2951c is involved ... tuberculosis, i.e DIMs and PGL-tb; and (b) to address the question of the function of the two related molecules DIM A and DIM B According to the accepted model of DIM and PGL biosynthesis [17], DIM A and ... mutants andthe analysis of their growth characteristics in various cellular and animal models may lead to the identification of the structural motif(s) of DIMs involved in pathogenesis, and thereby...
... involved in the biosynthesis of surfactin, whichis composed of four domains (C-A-PCP-TE) In this structure, the C domain andthe AN form a structured platform onto whichthe AC andthe PCP domain are ... gramicidin S synthetase I (GrsA; EC 5.1.1.11), which consisted of the first two functional domains, namely the phenylalaninespecific A domain andthe PCP domain The terminal E domain was excised (the exact ... betweenthe A domain andthe PCP, which probably allows the PCP to travel between different catalytic centres In fact, this linker constituted the only connection betweenthe two domains in the...
... vừa khép lại vấn đề vốn có nhiều ý kiến khác nhau, vừa mở hướng theo quan điểm chủ nghĩa vật biện chứng chủ nghĩa vật lịch sử, theo cách định nghĩa sau: Tính dân tộc văn hoá nghệ thuật kết tinh ... tộc văn hoá nghệ thuật, bản, chúng vào thật khác biệt dân tộc, dân tộc có mà dân tộc khác Nếu theo logíc vấn đề tính dân tộc văn hoá nghệ thuật hiểu bất biến, định hình, chí thay đổi, tạo nên ... tượng mâu thuẫn dân tộc tính đại, tính dân tộc tính quốc tế, truyền thống với đại Chúng ta biết, theo quan niệm vật biện chứng vật, tượng giới vật chất vận động biến đổi phát triển không ngừng,...
... A(G) isthe adjacency matrix of G Then χ(G) = 32 andthe electronic journal of combinatorics (1997), #R19 and α(G) < min{ rank(B) |B ∈ B(G)} by theorem Acknowledgement The author is grateful to the ... us further information about the graph G (i) If v ∈ S then exists u ∈ S such that u − v Indeed, Yvv = and Xwv ≥ for all w ∈ S − Hence, w∈S Xwv = and Xuv > for some u ∈ S (ii) If v , v ∈ S and Xuv ... We know from (i) and (ii) that G(Vu ) is a clique and V (G) = ∪u∈S Vu Hence, χ(G) = α(G) Corollary If χ(G) ≤ α(G) + then χ(G) = min{ rank(B) |B ∈ B(G)} For example, consider the Petersen graph...
... is active, and consider the case where p = a Since n isthe greatest letter, andis not at an end of either one, p and p have the same active letters The letter i1 on the left of a is ... be the successor of the rightmost element j of p which precedes i andwhichis less than i If there is no such element j, then let i be the successor of the root The correspondence p → T (p) is ... of the path P (A), and e isthe minimal edge of this path Hence e isthe minimal edge of the reduced path of A By definition of α, we have br = ω if and only if ω separates R and e, that is if and...
... metabolism and lipolysis [22], was also increased in the adipocytes treated with the PPARg agonist In contrast to the differences between fatty acid oxidation and synthesis associated with PPARδ and ... activation of the two nuclear receptors To unambiguously define the mechanisms by which PPARδ and PPARg alter the metabolism of adipose tissue, this was further characterized by 13 C-stable isotope ... glucose uptake and glycolysis in white adipose tissue [2,21] A consistent observation from both the white adipose tissue and 3T3-L1 adipocytes exposed to the PPARg agonist was a decrease in the concentration...
... in this field, and this discrepancy of interest will eventually put pressure on politicians to decide on the issue, in the absence of any real popular debate This paper will discuss themain ... widespread use, and from smokers' ambivalence about their status On one hand, they usually know that they are tobaccodependent, but, on the other hand, they often like to see themselves as free, and responsible ... NGOs The lack of smoker members of anti-tobacco lobbies is surprising, since tobacco use is by far the most common addiction, andisthe number one killer with respect to drug use Given the central...
... represented by the histograms in Figure The use of this constrained dataset permitted a direct comparison betweenthe distributions for coding and noncoding sequence in the vicinity of the stop codon ... monkeys and humans shared a common ancestor around 25 Mya, andthe genomes of these organisms are highly conserved with human [33,35,38] Furthermore, the biology of these organisms is such that they ... expressed in all tissues or to show differential levels of expression betweenthe tissues analyzed Discussion Primate models are essential to the study of human biology and disease and to the development...