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iv— inborn errors of cholesterol and bile acid synthesis

Application of Hydrothermal Reaction to Biodegradability Improvement of Refractory Pollutants: Structural Conversion of Di- and Trichloroacetic Acid to Biodegradable Products

Application of Hydrothermal Reaction to Biodegradability Improvement of Refractory Pollutants: Structural Conversion of Di- and Trichloroacetic Acid to Biodegradable Products

Môi trường

... % of glycolic acid and % of formic acid were detected in The amount of malic acid decreased, and was converted into more simple organic acids as reaction time increased Glycolic acid increased ... Effect of reaction time on the content change of products from DCAA and TCAA by o hydrothermal reaction at 250 C and MPa Journal of Water and Environment Technology, Vol.1, No.2, 2003 acid, % of ... partial destruction of MCAA by hydrolysis, production of biodegradable glycolic acid and decomposition of glycolic acid to other organic acids were reported [11] Based on the results of ion chromatography,...
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Báo cáo khoa học:

Báo cáo khoa học: "Isolation of cholesterol-lowering lactic acid bacteria from human intestine for probiotic use" ppsx

Báo cáo khoa học

... cholesterol- lowering lactic acid bacteria 393 Table Number of acid- and bile- tolerant lactic acid bacteria isolated from the human intestine for probiotic use Acida Bileb BSHc Streptococcus Lactobacillus Bifidobacterium ... without bile salt and to 102.9 mg/dl (49.4%) in the 0.3% bile salt MRS broth Eight strains of Lactobacilli decreased cholesterol by more than 50% in the MRS broth regardless to the presence of bile ... absorption kinetics of free bile salts in the GIT Fecal loss of bile salts may indeed result in an increased requirement for cholesterol for maintaining serum cholesterol levels Klaver and van der Meer...
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Báo cáo sinh học:

Báo cáo sinh học: " Parallel selection of ethanol and acetic-acid tolerance in Drosophila melanogaster populations from India" pot

Báo cáo khoa học

... by standard statistical formulae (Ferguson, 1980) Ethanol and acetic -acid tolerance patterns of mass cultures of each of populations of D melanogaster were assessed following the procedure of ... ethanol and acetic acid The parallel utilisation of ethanol and acetic acid in Indian tropical and subtropical populations of D melanogaster concur with such data on temperate populations of D melanogaster ... for ADH (Harris and Hopkinson, 1976) The genetic control of ADH banding patterns was interpreted from the segregation patterns of enzyme electromorphs of l parents, F and F progeny of several single-pair...
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báo cáo khoa học:

báo cáo khoa học: " Transcriptional regulatory programs underlying barley germination and regulatory functions of Gibberellin and abscisic acid" doc

Báo cáo khoa học

... amino acid metabolism amino acid metabolism .synthesis amino acid metabolism .synthesis. central amino acid metabolism amino acid metabolism .synthesis. central amino acid metabolism.GABA amino acid ... amino acid and nucleotides, establish and maintain protein synthesis and transporting machinery, and remodel chromatin structure to support the cell division and expansion occurring in late and ... compared and displayed as Venn diagrams 10A compares GA and germination; 10B compares ABA and germination; and 10C shows the comparison of GA, ABA and germination The number of probe-sets and their...
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Báo cáo y học:

Báo cáo y học: " Variability over time and correlates of cholesterol and blood pressure in systemic lupus erythematosus: a longitudinal cohort study" pptx

Báo cáo khoa học

... of this study was to describe and quantify variability over time of TC, SBP, and DBP and to determine their correlates in patients with SLE We used > 26,000 measurements of each of TC, SBP, and ... wherein all of three of TC, SBP, and DBP had been measured and recorded Definitions of variables Age and disease duration at the time of each visit were reported in years Disease dura- Page of tion ... number of visits Likewise, the status of 46.4% of patients varied between normotensive and hypertensive, with hypertension recorded for 14% of the total number of visits The total and the within- and...
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Effects of glucocorticoids and retinoic acid on activated rat microglial cells in primary culture

Effects of glucocorticoids and retinoic acid on activated rat microglial cells in primary culture

Cao đẳng - Đại học

... regulator of JNK and p38 MAP kinases in microglial cells exposed to LPS Blockade of MKP-1 expression by triptolide enhanced the phosphorylation of JNK and p38 MAPK pathways and the mRNA expression of ... distribution of actin and tubulin and lack membrane localization of these proteins and process formation (Eugenin et al 2005) When cells are treated with a chemotactic stimulus, rearrangement of actin and ... treatment of inflammation and a number of autoimmune disorders (Wilckens and De 1997) The immuno-suppressive properties of GCs have been ascribed to their ability to suppress the synthesis of a number...
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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx

Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx

Báo cáo khoa học

... of PGE2 and PGI2 which was mainly due to a strong transcriptional activation of the Cox-2 gene (and to a lesser extent of PGIS and mPGES-1) Under the same experimental conditions expression of ... neither by Raf induction of PGI2 synthesis in the absence of PPARb activation the pharmacological inhibition of PGI2 synthesis nor by the simultaneous overexpression of Cox-2 and PGIS Our data therefore ... of both prostanoids was detectable within h of 4-OHT treatment and after 24 h reached values > 100-fold of the uninduced basal levels In the presence of AA (Fig 1A, bottom panel), synthesis of...
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Báo cáo y học:

Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

Y học thưởng thức

... Treatment of obese rhesus monkeys with GW 501516, a selective PPARδ agonist, led to a significant improvement of metabolic traits characterized by a rise of HDL and lowering of LDL, triglycerides, and ... interaction between PPARδ and apoE Allelic variation in apoE is known to be associated consistently with plasma concentrations of cholesterol, LDL cholesterol and apoB in men and women (reviewed in ... N, Ballantyne CM, Gotto AM, Marian AJ Effects of PPARα, γ and δ haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein...
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Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas

Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas

Môi trường

... fatty acids, and the ratio of each fatty acid RESULTS AND DISCUSSION Characteristics of carbon stable isotope in Z japonica The mean δ13C of Z japonica was -12.4 ± 1.6‰ in the leaves and stems, and ... leaves and stems and about 36 kinds of fatty acids in the roots and rhizomes of Z japonica We focused on the fatty acid content of Z japonica , because we needed to exclude the influence of a ... characteristics of carbon stable isotope and fatty acid structure of Z japonica Furthermore, we compared the characteristics of carbon stable isotope and fatty acid structure of Z japonica with those of the...
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ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY

ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY

Khoa học xã hội

... adverbs of manner? I.1.2 Formation of adverbs of manner I.1.3 Position of adverbs of manner 11 I.1.4 Classification of adverbs of manner 13 I.1.5 The differing functions of adverbs of manner and ... more than one kind of adverb in a sentence ( adverb of manner, adverb of place and adverb of time), adverb of manner precedes adverb of place and adverb of time So the order of these adverbs is ... feature of the learning process EA research is often carried out with the following steps: Collection of a sample of learner language Identification of errors Description of errors Explanation of errors...
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A study on prepositions of direction and some errors made by vietnamese learners

A study on prepositions of direction and some errors made by vietnamese learners

Khoa học xã hội

... of time and knowledge, I have no ambition of covering all kinds of preposition and research errors made by learners of all countries in the word, but only prepositions of direction and some errors ... Prepositions of direction and some errors made when using them attracts my attention the most Hence, the name of subject of my graduation paper is “A study on prepositions of direction and some errors ... Prepositions of Cause 13 Chapter II: Prepositions of direction Prepositions of direction 1.1 What are prepositions of directions 14 1.2 List and meanings Analysis of some examples of preposition of direction...
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Tài liệu MASTER OF BUSINESS ADMINISTRATION (MBA) II TO IV SEMESTERS (FULL TIME) CURRICULUM AND SYLLABUS doc

Tài liệu MASTER OF BUSINESS ADMINISTRATION (MBA) II TO IV SEMESTERS (FULL TIME) CURRICULUM AND SYLLABUS doc

Quản trị kinh doanh

... Basics Understanding of Brands – Definitions - Branding Concepts – Functions of Brand Significance of Brands – Different Types of Brands – Co branding – Store brands UNIT II BRAND STRATEGIES ... concept of risk and return of a single asset and of a portfolio- Valuation of bonds and shares-Option valuation UNIT II INVESTMENT DECISIONS Capital Budgeting: Principles and techniques - Nature of ... BRAND COMMUNICATIONS Brand image Building – Brand Loyalty programmes – Brand Promotion Methods – Role of Brand ambassadors, celebraties – On line Brand Promotions UNIT IV BRAND EXTENSION Brand...
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Tài liệu Báo cáo khoa học: Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus docx

Tài liệu Báo cáo khoa học: Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus docx

Báo cáo khoa học

... of Glu, glycosylation of Ser or Thr, bromination of Trp, sulfation of Tyr, cyclization of N-terminal Gln, and epimerization of several different residues It is quite rare for such a variety of ... structure of conomarphin was similar to those of other conotoxin cDNAs The cDNA-encoded precursor of conomarphin consisted of a conserved M-superfamily signal peptide of 25 residues, a proregion of ... bonds for Asn11(CO)–Trp14(HN) and Ser12(CO)– Thr15(HN), and confirmed by the slow solvent exchange kinetics of the amide protons of Trp14 and Thr15 The observation of two small 3JHN-Ha coupling...
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Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt

Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt

Báo cáo khoa học

... the vicinity of the active site (Fig 2) Three of the six cation ligands are main-chain oxygen atoms, and three are the side-chain oxygen atoms of N296, E342 and S387 The glutamic acid and asparagine ... crystal structures of both CHH and CHN enzymes [1,4,5,11,12] have contributed to the understanding of the role of conserved residues in the active site of CHH condensing enzymes, and analogies have ... of wild-type, H298E and H298Q proteins in 30 assays The amount of labeled substrate present at the start of the reactions is shown in the first lane C is a standard consisting of malonyl-ACP and...
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Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Báo cáo khoa học

... 4¢-phosphopantothenic acid, CTP and cysteine The synthesis of PPC occurs in two half reactions starting with the formation of 4¢-phosphopantothenoyl-CMP (activation of the carboxyl group of 4¢-phosphopantothenate) ... Asn210 and Ala276 are important for the second-half reaction and are part of the active-site of CoaB; these residues may be directly involved in binding of one of the substrates, the amino acid ... activity of His-CoaB R206Q and A276V The synthesis of 4¢-phosphopantothenoyl-CMP (–cysteine, upper part of the figure) and of 4¢-phosphopantothenoylcysteine (+ cysteine, lower part of the figure) by the...
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Tài liệu Báo cáo khoa học: The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain pdf

Tài liệu Báo cáo khoa học: The SCO2299 gene from Streptomyces coelicolor A3(2) encodes a bifunctional enzyme consisting of an RNase H domain and an acid phosphatase domain pdf

Báo cáo khoa học

... (Keio University)’ and a grant from New Energy and Industrial Technology Development Organization (NEDO) of the Ministry of Economy, Trade and Industry of Japan (Development of a Technological ... volume of 100 lL Each assay contained 100 mm acetate ⁄ NaOH (pH 5.0) and 10 mm of substrate Assays were initiated by the addition of substrate, progressed for 10 at 37 °C, and terminated by lL of ... trichloroacetic acid After dilution with 100 lL of water, 25 lL of 2.5% ammonium molybdate in 2.5 m H2SO4 and 10 lL of Fiske–Subbarow reagent were added The mixtures were incubated for 20 at 37 °C and absorbance...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Báo cáo khoa học

... transformant and was used for the purification of GALA Growth of this transformant and subsequent purification of the enzyme were performed as described in Materials and methods Purity of the preparation ... between and 4.5 No activity of GALA could be detected against any of the transgalactooligosaccharides listed in Materials and methods Purification and characterization of GALA Hydrolysis of arabinogalactans ... Double stranded sequence was determined for a region of this construct containing galA and some of the flanking regions, resulting in the genomic sequence of A niger galA The presence of one putative...
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Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

Báo cáo khoa học

... amino acids (i.e Q, N, S, and T) and an increase in charged amino -acid residues (i.e K, E, and R) in hyperthermophilic proteins As S and T can catalyze the deamination and backbone cleavage of Q and ... volume of blue dextran (X) Protein standards; (A) BLXI Linear regression (1), with an r of 0.951, is based on the elution data of all four protein standards Linear regression (2), with an r of 0.981, ... an r of 0.981, is based on the elution data of the 200, 150, and 66 kDa protein standards Linear regressions (1) and (2) give molecular masses of 200 and 177.5 kDa, respectively, for BLXI q FEBS...
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Báo cáo khoa học: ATP-dependent ligases in trypanothione biosynthesis – kinetics of catalysis and inhibition by phosphinic acid pseudopeptides doc

Báo cáo khoa học: ATP-dependent ligases in trypanothione biosynthesis – kinetics of catalysis and inhibition by phosphinic acid pseudopeptides doc

Báo cáo khoa học

... phosphonic and phosphinic acid derivatives of GSH as moderate Kinetics and inhibition of ATP-dependent ligases inhibitors of CfGspS [38] The most active of these was a phosphonic analogue of GSH ... auto-oxidation of NADPH and hydrolysis of ATP in the coupling system, the net rates of endogenous ATPase activity ($ 0.01% of kcat) in the presence and absence of inhibitor are 1.4 ( 0.9) ã 10)3 and 3.0 ... insertion of 17 amino acids in the amidase domain and two in the synthetase domain (one of 14 amino acids and the Fig Conservation of key functional residues identied for EcGspS in CfGspS and TryS...
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