genome the transcriptome and the predicted brain proteome of honey bees
RUNX3 acts as an ocogene through a hedgehog dependent pathway in selected human neoplasms
... RUNX3 therapeutics 28 ii CHAPTER HYPOTHESIS 30 2.1 Original hypothesis: Preliminary data leading to the focus of this thesis 30 2.2 Subsequent hypothesis: Core of the thesis 30 CHAPTER MATERIALS AND ... (Kalderon 2005) The binding of SHH inactivates PTCH1 with the help of coreceptors and relieves the suppression of SMO, leading to the posttranslational modification of the glioma (GLI) family of zinc-finger ... inhibition of SMO SMO migrates from the intracellular endosome to the cell membrane of the cilium SMO is activated within the cilium and promotes the activation of GLI proteins (GliA) These enter the...
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Báo cáo khoa học: MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma pdf
... Thus, the identification of the oncogene, miR-373, and its target gene, PPP6C, may help us to understand the molecular mechanism of tumorigenesis in HCC and may have potential diagnostic and therapeutic ... mutant), the 3¢-UTR and mutant 3¢-UTR fragments of PPP6C transcripts amplified by RT-PCR were inserted into the vector backbone downstream of the EGFP gene between the BamHI and EcoRI sites of the ... invasion of the cancer cells [19] The function of miR-373 on HCC cells needs to be elucidated in the future The fundamental function of miRNAs is to regulate their targets by direct cleavage of mRNA...
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báo cáo hóa học: " Methyl salicylate 2-O-b-D-lactoside, a novel salicylic acid analogue, acts as an antiinflammatory agent on microglia and astrocytes" docx
... edema model in mice [10] Therefore, we investigated the capacity of DL0309 to suppress the production of pro-inflammatory cytokines (IL-6, IL-1b, and TNF-a) and the expression of inflammation-related ... inflammation-related proteins (iNOS, COX-1, and COX-2) in LPS-activated microglia and astrocytes, and we explored the association of these effects with activation of the NF-B pathway Primary rat glia ... effective in the treatment of these disorders NF-B is known as an important regulator of various genes involved in the production of many pro-inflammatory cytokines and enzymes related to the inflammatory...
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Báo cáo y học: "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note" potx
... posterior border of the clavicular head of the sternocleidomastoid and then curved laterally over the medial 2/3rd of the superior surface of the clavicle The platysma was incised and the supraclavicular ... carbon dioxide (ETCO2) and is one of the standards of monitoring in anesthetic care The authors describe the use of capnography as an aid in the intraoperative localization of the phrenic nerve http://www.jbppni.com/content/3/1/14 ... noise, and high recording electrode impedance which may diminish reliability and increase the duration of the procedure.[7] On the other hand, capnography is a routine and mandatory anaesthetic...
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Báo cáo y học: "Correspondence in relation to the case report "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note." published in May issue of Journal of Brachial Plexus and Peripheral Nerve Injury" potx
... localization: effects of cutaneous electrode placement and duration of stimulus on motor response Anesthesiology 2004, 100:1526-1530 Raj PP, Andres JD, Grossi P, et al.: Aids to localization of peripheral ... of regional anesthesia Edited by: Raj PP New York: Churchill Livingstone; 2003:309 Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the ... is not used They have also mentioned something about progressive reduction in ETCO2 level in subsequent capnogram tracings But they have not given any valid explanation to the cause of this occurrence...
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Báo cáo y học: "Response to comments on "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note"" docx
... Journal of Brachial Plexus and Peripheral Nerve Injury 2008, 3:21 http://www.jbppni.com/content/3/1/21 With increase in the amplitude of current, there is further increase in the force of diaphragmatic ... hope the response addresses the concerns of the reader Thanking you Hemant Bhagat, Anil Agarwal, Manish S Sharma Competing interests The authors declare that they have no competing interests They ... Publish with Bio Med Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical researc h in...
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Báo cáo y học: "Ketamine as an adjuvant in sympathetic blocks for management of central sensitization following peripheral nerve injury" pptx
... developed burning pain, allodynia in the distribution of the sciatic nerve and edema of the effected limb Pharmacotherapy with maximum doses of Gabapentin, Amitryptalline and Tramadol gave him moderate ... in the type of receptors may either decrease the inhibitory receptors like GABA or increase in the excitatory receptors like NMDA [8] These plastic changes that increase the sensitivity of the ... on the other hand has been effective after onset of hyperalgesic symptoms [8] There are changes in the ion channels especially Na+ and Ca2+ channels in neuropathic pain Therefore combination of...
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Báo cáo khoa học: " Geographical Information System (GIS) as a Tool in Surveillance and Monitoring of Animal Diseases" potx
... municipalities, and in the veterinary field, veterinary districts which mostly consist of one ore more municipalities The themes of veterinary districts were manually created and derived from the themes of the ... application The information of the locations of the farms with animal production as well as their production type and herd sizes are collected from these two registries The disease recording system of the ... Further, the maps can assist the field veterinarians to plan their work in the current situation, and for the veterinary authorities in how to handle a potential outbreak Analysis of clustering of...
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Báo cáo y học: " A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus" docx
... diversity of HIV-1 is thought to be generated by the low fidelity of its reverse transcription and frequent recombination of the genome [39] Mutation of amino acid sequences in the V3 domain of the ... inhibition of the coreceptor activity of FPRL1 by the fMLF peptide It has been reported that the coreceptor functions of CCR5 and CXCR4 for HIV-1 infection can be inhibited by their ligands, RANTES and ... Effects of anti-CD4 MoAb, the fMLF peptide, and RANTES on the susceptibility of cells to HIV/SIV strains Figure Effects of anti-CD4 MoAb, the fMLF peptide, and RANTES on the susceptibility of cells...
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Application of titanium silicide as an interconnect in deep submicron integrated chip manufacturing
... sharp lines from the standard and broad lines from the unknown Let βs be the measured breadth, at half-maximum intensity, of the line from the standard Then β is given, not simply by the difference ... understand some of the common techniques used to overcome these obstacles while exploring new methods with existing manufacturing tools The kinetics of the phase transformation and properties of the ... encounters a set of regularly spaced scattering objects provided that the wavelength of the wave motion is of the same order of magnitude as the repeat distance between the scattering centers The German...
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Application of titanium silicide as an interconnect in deep submicron integrated chip manufacturing 2
... and good thermal stability Together with new and better manufacturing tools, it is in the opinion of the author that the usability of TiSi2 can be further extended Among the many techniques of ... energy and allows the formation of the Ti5Si4 phase Although the formation of the Ti5Si4 phase also reduces the Gibbs free energy of the system, the activation free energy barrier for the C49-TiSi2 ... suggest that the new exothermic peak could be due to the formation of Ti5Si3 and Ti5Si4 phases It is believed that the formation of Ti5Si3 reduces the Gibbs free energy of the system prior to the formation...
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Báo cáo khoa học: Identification of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx
... suggesting that the increase of Luc activity by SA reflect the levels of transcription and translation of Hsp105, not due to an indirect effect of SA on the basal activity of Luc Enhancement of Luc activity ... doses of SA (45–60 mM) induced the activation of promoter activities of Hsp105 and Hsp70 as well as the accumulation of Hsp105a and Hsp70 in mouse and human cells, although relatively low doses of ... induced the activation of HSF but not transcription of hsp genes in cells Thus, relatively high doses of SA seemed to be required for the induction of the transcription of hsp genes and the accumulation...
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USING BRAND AS AN EFFECTIVE WEAPON TO COMPETE IN THE MARKET: A CASE STUDY OF NHAT LINH COMPANY
... is the soul of the brand? What are the fundamental beliefs and values that drive the brand? What are the competencies of the organization behind the brand? What does the organization behind the ... understand the following aspects of its territory: • • • • The size and scope of the market; The segment in the market; The players in the market and their positions; The trends in all these areas ... brands over the others • Brand loyalty: brands command high degree of brand loyalty The loyal consumer will walk out of the store to buy it elsewhere in case of stock-out of his favorite brand...
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THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES SUSTAINABILITY EFFECTS OF FORMALISATION CONSIDERING HO CHI MINH CITY – VIETNAM AS AN EXAMPLE
... snacks and cigarettes for the guests of kerbside bars The list of informal sector activities is limited only by the business ideas of its actors and the demand for the goods and services they offer ... quality of the collected materials (e.g by the introduction of compaction) and be a reason for brokers to reject the materials On the other hand the quality of the materials collected by the informal ... owners often buy the goods from scavengers for just % of the price the industry pays and therefore gain a profit of 95 % NAS and JAFFE (2004) described the relationship between shopkeepers and informal...
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Báo cáo " Imperialism of communicative language teaching and possible resistance against it from teachers in Vietnam as an English foreign languages context " doc
... misconception of CLT, their methodology, the relationship among them, the relationship between teachers and learners, teachers’ training program, and their salary - Teachers’ misconception of CLT Since the ... classroom They should pay due attention to the present situation of teachers The unanswered question is what should be done to increase the quality of teachers’ profession and their life The paper ... Journal of Science, Foreign Languages 24 (2008) 167-174 as for the purpose of meaningful communication, and language as the means for that purpose The focus of language teaching, therefore, is on the...
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Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt
... tPA and the resistance of the reactive loop to cleavage The lower portion of b-sheet A is filled by unfolding of the F-helix (yellow) Right, the F-helix is displaced by the reactive loop of another ... 24 h Assessment of the conformation of Ser52Arg neuroserpin The most likely cause for the inactivity of Ser52Arg neuroserpin and inaccessibility of the reactive loop is that the mutant had adopted ... 25 °C and 95 °C using a heating rate of °CÆmin)1 at a concentration of 0.7 mgÆmL)1 The second derivative of the resulting data was used to calculate the inflection point of the transition and hence...
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Báo cáo " An assessment of healthcare system accessibility of local communities in Yen Chau District, Son La Province " pot
... is the value of each cell; P is the population of each commune; and S is the total area of settlement. According to the Regulation of the Government and the results of local ... people to public services. The size and structure of population are affected on the possibility of public service, when local people will identify the need of public services during their life in the particular period. ... is considered as the site when the efforts to get there is acceptable to the target groups (local communities). Therefore, the concepts and the uses of accessibility are close related to the transportation ...
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Báo cáo khoa học: Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector pot
... (solid circles) The discontinuous line and the open diamonds represent the result obtained in the absence of L-AMP and in the presence of the indicated concentrations of CoA All the indicated quantities ... performed The effect of the concentration of CoA and dephosphoCoA on the rate of the thiolytic reaction was determined measuring the rate of L-CoA and L-dephospho-CoA formation, respectively The reaction ... Except for the phosphate buffer concentration in the eluent and the ux rate (which was 4.9 mm and mLặmin)1, for the case of CoA, and mm and 1.7 mLặ min)1, for the case of dephospho-CoA), the aliquots...
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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt
... 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien A leucotrien B prostacyclin (PGl2) PG-synthetase PG sơ cấp (PGE2, D2, P2) TX synthetase TX A2 leucotrien C TX B2 leucotrien D ... đến sinh lý bệnh học tế bào ung th: in vitro, curcumin làm ngừng chu kỳ tế bào u, thúc đẩy chết theo chơng trình (apoptosis) Tuy nghiên cứu hạn chế, nhng thấy curcumin có tác dụng chống tạo mạch ... sàng Acid boswellic giúp biệt hoá nhiều dòng tế bào bệnh bạch cầu Với nồng độ thấp, làm tăng chết theo chơng trình (apoptosis) dòng tế bào Glia (thần kinh đệm) Một số thực vật khác đáng quan tâm...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008