deposit the main activity of the region is coal mining and coal based industries the various sources of pollution in dhanbad jharia can be categorized as under
... and that, in both species, P450c17 is involved inthe biosynthesis of androstadienol Effect of cyt b5 on DHEA and androstadienol biosynthesis In order to determine the effect of cyt b5 in P450c17 ... substrate As observed in Fig 3, the biosynthesis of androstadienol in humans (A) and pigs (B) does not require prior formation of 17a-OH-preg and DHEA The lack of androstadienol synthesis inthe presence ... DHEA As shown in Fig the stimulation of DHEA and androstadienol production from preg increases with increasing amounts of cyt b5 in presence of endogenous levels of P450red In presence of these...
... independence of students in teaching process is a vital demand, a surviving issue for the development of Education and Training sector ofthe country now andinthe future The thesis has systemized ... isis heated) under influence of external electric field Then the teacher can enable easy and stable understanding of current in vacuum (figure 2.7 inthe thesis) Figure 2.7 SE of current in ... Tong… There is one common thing inthe above mentioned studies which isthe importance of establishing the issue to bethe centre ofthe method, and students are encouraged to find the solutions and...
... Fig 4B) Calculating the signal intensity ofthe reactions ofand 10 lm NADPH revealed that the efficiency of PMCA was increased by 2.59-fold inthe presence of Fig The enhancement of NADPH for ... quantity of PK-resistant rPrP Therefore, we speculate that certain binding domains of pyridine nucleotides may exist within the PrP molecule Through transferring electrons, the energy class of PrP ... leading to the protein being more easily converted to PrPSc The level of extracellular NADPH or NADH has not been determined [35], so it is unclear whether PrPC on the cell surface canbein uenced...
... inthe kinase assay Because in many cases we noted that the clusters seemed to occur near the carboxyl- or amino-terminus ofthe proteins (as inthe case ofthe Cdc6p amino-terminal domain; Figure ... enrichment is somewhat less in this set is consistent with some ofthe enrichment inthe known set being due to bias in their discovery, but also with some false-positive findings being picked up inthe ... and between the end ofthe cluster andthe end ofthe protein We then took the minimum of these divided by the length ofthe protein to bethe position We computed the foldedness as If = 2.785...
... this list canbethe springboard for further ideas and, more importantly, the implementation of solutions to reduce diesel pollutionThe list is divided into three goals: reducing the impact of ... truckers find all the services they need on the grounds ofthe Port of Oakland, instead of traveling into West Oakland Providing truck services at the Port of Oakland would eliminate hundreds of truck ... isinthe air Given the prevalence of diesel pollutionin West Oakland, andthe growing body of evidence on diesel’s toxicity, reducing diesel pollutionis critical to protecting the health of...
... ATPases from thermophilic organisms, including four different chaperonins [6] and two DNA ligases [7,8], has been reported It was hypothesized that using ADP as an energy source instead of ATP in ... phosphofructokinases in thermophilic archeaons can also use ATP as a phosphoryl transfer donor [9–12] Here we report an apparent ADPase activityin preparations ofthe recombinant ATPase domain ofthe ... published studies describe their samples as ‘purified to homogeneity’ For at least three reasons, potential contamination can easily be overlooked inthe purification of recombinant proteins of thermophilic...
... Anti-actin antibody was raised against a peptide mapping at the C-terminus of actin of human origin and was reactive against both actin isoforms Antibody against type I collagen was purchased from ... prostaglandin synthesis toward the synthesis of PGD2 and its derivatives This hypothesis is supported by literature data showing that, in chondrocytes, 15ΔPGJ2 inhibited the expression of mPGES and ... available ELISA assay that allows determination of phospho-p38, total p38 and cell number inthe same assay Cells were treated with IL-1a inthe absence andinthe presence of 20 μM MGDG Based on the...
... Domestic wastewater has originated from: - Households and individuals: + Cooking, washing dishes, cleaning, washing clothes, bathing + Using the toilet + Washing floor surface and washing cars, ... aluminum from the slag *Casting Aluminum Aluminum casting processes are classified as Ingot casting or Mould casting Time for a product is about hour and 30 minutes Molds for casting aluminum ... Number of patients Diseases Proportion (%) Condensed Aluminum Condensed Aluminum aluminum casting aluminum casting Respiratory disease 10 33.3 23.3 Skin Diseases 30.0 10.0 Gastrointestinal disease...
... water andthe incidence of diarrheal disease in children underthe age of confirms this finding: the lack of access to piped water is significantly associated with excess cases of diarrheal disease and ... level in China in 2001, 2003, and 2005 The problem remains serious inthe south and southeastern portions ofthe country As illustrated below, there are some indications that themain areas affected ... Jianping, Ling Lixin, Fu Deqing and WuHuaimin Zhao Yaoming has participated from the Ministry of Agriculture A team from the Water Resources and Hydropower Planning and Design Institute ofthe Ministry...
... andthe patients' assessment of disease activity) and DAS28-3 (excluding patients' assessment of disease activity from DAS28) indices; these indices have been and validated and, for reasons of ... Modifications to the original DAS index have been applied, yielding the DAS28 (which is a composite index that includes variables such asthe number of tender and swollen joints using 28 joint counts, ... College of Rheumatology criteria) and RA stage (determined according to Steinbrocker criteria), were recorded Disease activity was assessed using the Disease Activity Score (DAS) in 28 joints, DAS28-3...
... This finding isin line with the data in this study, and suggested that the maintenance of circulating lymphocytes number can recruit many anti-tumor lymphocytes into the irradiated tumor during ... the effectiveness of CRT Acknowledgements This study was funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan, andthe Ministry of Health, Labor and Welfare of ... approval by the Ethics Committee ofthe University of Tokyo, and written informed consent was obtained from the patient for publication of this case report and accompanying images A copy ofthe written...
... could be explained by improved recording of cases and disruption of some ofthe control measures and supervision during the crisis Trends in malaria incidence in Timor-Leste during the crisis presents ... limitations of seizing the momentum from the crisis to improve aspects of information and health system functioning The procurement of RDT and artemether-lumefantrine at that time ofthe crisis was justified ... outbreaks during the crisis The negative side ofthe crisis on malaria is that it disrupted training programs, impeded the MoH in attracting Global Fund resources, andthe intervention was overly...
... polymorphisms inthe 5’-flanking regionof NPPB andthe presence of EH Inthe present study, a novel VNTR was discovered, and a significant association between the VNTR and EH was found in female ... relationship between the genotype and BMI and found no significant association In conclusion, a novel VNTR inthe 5’-flanking regionofthe NPPB gene was discovered This polymorphism was associated ... SD The Hardy-Weinberg equilibrium was assessed by doing chi-square (χ2) analysis Differences inthe clinical data between the EH and NT groups were assessed by analysis of variance (ANOVA) The...
... have been implicated to function inthe RAS/cAMP pathway These include the two disrupted genes, GPA2 and RAS2, the second RAS gene RAS1, SCH9, a protein kinase A homologue, which previously has been ... Colavizza, D & Thevelein, J.M (1998) Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling inthe yeast Saccharomyces cerevisiae EMBO ... ura3–52/ura3–52 his3:hisG/his3:hisG leu2::hisG leu)2::hisG S1278b; MATa/a sut2::S.pombe his5+/sut2::S.pombe his5+ ura3–52/ura3–52 his3:hisG/his3:hisG leu2::hisG/LEU2 TRP1/trp1::hisG S1278b; MATa ura3–52 his3:hisG...
... biosynthesis: whilst SSII and SSIII have a major role inthe synthesis of amylopectin, it has been suggested that SSI is mainly involved inthe synthesis of small chains of this fraction Furthermore, ... showing that there is a physical interaction between the N- and C-terminal domains of SSIII in vitro Mapping ofthe CD-binding regioninthe N-terminal SBDs In order to identify the SBD region ... phenotype and an increase in total SS activity [8] It has also been described that the N-terminal regionof SSIII can interact with SSI [13] The possible regulatory role of this protein makes this isoform...
... arginase II is nonhepatic and occurs inthe mitochondrial matrix [27–29] andis involved in homeostasis of ornithine for the further production of proline and glutamate [30] Both isoforms have been ... break inthe presence of Mg2+ inthe NP ensemble Inthe NPT ensembles, the interactions remain intact with and without Mg2+ but there is an increase inthe average standard deviation ofthe salt-bridge ... structures in this region (described below), remained in contact with the rest ofthe protein The protein stability of PfArg was monitored by the change in Ca rmsd during equilibration and sampling...
... domain ofthe substrate with the catalytic regionofthe kinase, on the one hand, andofthe positive charge ofthe RS domain with the negatively charged ‘docking groove’ of SRPK1, on the other hand ... there exists a domain on the kinase recognized by each ofthe two factors We excluded the possibility that such a domain is located inthe spacer regionofthe kinase because both SAFB proteins ... form complexes with the kinase underthe conditions ofthein vitro phosphorylation assays The Glu ⁄ Arg-rich regionis a candidate for repression ofthe kinase activity because of its particular...
... molecule was not inthe vicinity ofthe DNA-binding pocket of RecD Therefore, it is not clear how the invariant D and E residues ofthe ATP-binding pocket would affect nucleic acid binding Interestingly, ... However, the protein displays reduced ATPase activity (72%) and lacks DNA-unwinding activityin vitro This might result from the uncoupling of ATP hydrolysis and DNA unwinding, which has been shown ... domains ofthe protein at the bottom ofthe nucleotide-binding pocket [24] Corroborating this finding, when the conserved arginine residue at 284 position of motif IV in E coli UvrD helicase was...
... residues of a-sarcin (black)/RNase T1 (grey), after fitting ofthe backbone atoms ofthe residues involved inthe five-strands central b sheet of both proteins The protein view is maintained through the ... when 500 ng of protein were assayed, the lowest detection limit of this assay being 50 ng of wildtype protein [20] A quantitative analysis ofthe ribonuclease activityof a-sarcin has been developed ... this residue is required for the specific ribonuclease activityofthe protein against ribosomes and secondly, because this residue is essential for the binding ofthe protein to the membranes...
... [29-32] The LEL of CD81 has been identified asthe binding regionof HCV E2 and critical amino acids for maintaining this interaction have been determined [33,34] On the other hand, while several ... classifying then as group I mutants and implicating them as being directly involved in E2 binding to CD81 In conclusion, we have determined that the second and third putative CD81 binding regions ... identification of these regions as putative CD81 binding domains, the binding ofthe mutants to recombinant soluble CD81-LEL [4] was assayed In these experiments, binding of HCV E1E2 proteins to a purified...