1.1.8. Some preparations containing nifedipine on the Vietnamese market
1.1.9. Some studies on the extended-release drug delivery system containing nifedipine
a. Extended-release tablet dosage form
b. Extended-release pellet form
c. Sustained-release microspheres, microbeads form
1.2.1. Structure and mechanism of drug release
1.2.1.2. Mechanism of drug release
1.2.2. Advantages and disadvantages
- If the coating process was not well controlled, the nonuniformity coating results in different release patterns between batches, and there was a risk of film defects led to dose dumping.
1.2.3. Composition
1.3.1. In vitro drug release studies
USP 38 monographs of NIF extended-release tablets specified 8 dissolution tests for NIF extended-release tablets.