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Burden of Heart Failure • • • Lifetime risk > 20% for Americans >40 years of age 870,000 new cases diagnosed annually Prevalence in US: 5.7 million in of all Americans will be in the over Age Lifetime risk = > % 65 age bracket by 2050 VNM/NONCMCGM/0818/0052 HF is associated with high mortality rates PATIENTS DIE WITHIN ~50% OF YEARS OF DIAGNOSIS ~1 IN HF PATIENTS DIE WITHIN YEAR OF DIAGNOSIS2 Roger et alCirc Res 2013; 113:646-59; Levy et al N Engl J Med 2002;347:1397–402 VNM/NONCMCGM/0818/0052 VNM/NONCMCGM/0818/0052 ACC Focused update on HF, 2017 VNM/NONCMCGM/0818/0052 VNM/NONCMCGM/0818/0052 The Beginning of the Beta Blocker Story ◼ ◼ ◼ ◼ ◼ 1985, LDS Hospital, Jeffrey Anderson, et al 50 patients with IDC (EF
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