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Ngày T QU U TR B NH RÁM MÁ B NG LASER Q-SWITCHED ND: YAG K T H P BÔI TRI-WHITE SERUM T I B NH VI IH CC N -2020 Lê Minh Hồi1*, Hu 2 *Email: minhhoaibl@gmail.com TĨM T T t v : Trên th gi i, nh u tr rám má b ng Laser Qswitched YAG c coi m ng m i, mang l i nhi u k t qu kh quan, an tồn, bi n ch u tr T i Vi hi u qu u tr rám má b ng Laser Q switched YAG M c tiêu nghiên c u: t qu u tr b nh rám má b ng Laser Q-switched ND: YAG k t h p bôi Tri-white serum u: T tc b c ch nh rám má t i b nh vi ih cC n tháng 07/2020 Nghiên c u mô t c t ngang K t qu : K u tr , lâm sàng, có 13,41% b nh nhân k t qu cao/kh i nám rám má, 41,46% c i thi rám má, 45,12% c i thi n nh ng h p n m s MASI gi m theo th i u tr , gi m t ng c ng 4,91 ± 2, m so v u tr T l thành công 157 T P CHÍ CH CC NT S 33/2020 ph i h u tr nám da b ng Laser Q-switched ND: YAG k t h p bôi Tri-white Serum 82,22% K t lu n: T l thành công ph i h u tr nám da b ng Laser YAG k t h p bơi Triwhite Serum 82,22% T khóa: rám má, Laser Q-switched nd: YAG, FOB Tri-White serum ABSTRACT ASSESSMENT OF MELASMA TREATMENT RESULTS BY LASER Q-SWITCHED ND: YAG WITH TRI-WHITE SERUM AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2019-2020 Le Minh Hoai1*, Huynh Van Ba2 Bac Lieu Center for Disease Control Can Tho University of Medicine and Pharmacy Background: Recently, on over the world, melasma treatment with Q-Switched Nd: YAG has been considered a new trend, bringing many positive results, safety, and few complications in treatment In Vietnam, there are no studies to evaluate the effectiveness of Q-Switched Nd: YAG laser in melasma treatment Objectives: Evaluate the results of Q-Switched Nd: YAG laser combination Tri-white Serum in melasma treatment Materials and methods: All patients who were diagnosed with melasma at Can Tho University of Medicine and Pharmacy Hospital from April, 2019 to July, 2020 Cross-sectional descriptive studies Results: At the end of treatment, in clinical, there were 13.41% of patients with high results /melasma cured, 41.46% had significant improvement, 45.12% had slight improvement, no cases whichever was heavier MASI score decreased over time of treatment, decreasing a total of 4.91 ± 2.70 points compared with before treatment The success rate of Q-Switched Nd: YAG laser combination Tri-white Serum in melasma treatment is 82.22% Conclusion: The success rate of Q-Switched Nd: YAG laser combination Tri-white Serum in melesma treatment was 82.22% Keywords: Melasma, Q-Switched Nd: YAG laser, FOB Tri-White serum TV Trong nh c ch gi u tr rám má b ng Laser Q-switched u qu , bi n ch u tr [5] u tr cb t tr li u nh nhàng, i ngh u tr T i Vi t Nam, u tr rám má b ng Laser Qc th c hi n t i m t s u tr th m m da, b nh vi n chuyên khoa da li u tr th n tr c hi u qu c a bi n pháp v i Vi có nghiên c u, t ng k c th c hi n Vì v y, chúng tơi ti n hành nghiên c u nh t qu u tr rám má b ng Laser Q-Switched Nd: YAG k t h p bôi Tri-white Serum U ng nghiên c u ng nghiên c u: T t c b nh má t i B nh vi ih cC Tiêu chu n ch n m u: B 158 c ch c ch nh rám n tháng 07/2020 i B nh vi ng T P CHÍ ih CH CC NT cC Tiêu chu n ch - S 33/2020 [1]: s thành hình vịng cung Tiêu chu n lo i tr : - u Thi t k nghiên c u: Nghiên c u mô t c t ngang C m n m u: Áp d ng công th c tính c m c p ( p ) ng m t t l : n = Z21- /2 d2 Z: h s tin c y m c xác su ng v i Z=1,96 d: sai s ch p nh c Chúng ch n d=0,07 p: t l u tr hi u qu rám má b ng laser Q-Switched Nd: YAG Theo nghiên c u Yiyun Dong, Guoyu Zhou c ng s (2014) [10] v u tr rám má b ng laser QSwitched Nd: YAG t i Trung Qu c, t l t hi u qu u tr sau 16 tu n 88,57% nên ch n p=0,8857 Thay vào công th c tính c c m u t i thi 80 Chúng ch n 90 b nghiên c u + M 0: h t (s M 1: c i thi khó phát hi n) [2] c t : Có m [3]: n, vài v t h c t nh ) (t t màu h n so v i vùng da xung quanh, 159 T P CHÍ M M M + làm m M CH CC NT 2: c i thi n nh (nh t 4: n n th y rõ) t hi n m i ho s MASI Giá tr c a ch s [7]: nh : MASI