... body typi-cally affected include the extremities, genitalia, trunk,gastrointestinal tract, face, and larynx. Untreatedpatients with HAE are at risk for deadly attacks of laryn-geal swelling, ... equally1University of Cincinnati, Department of Internal Medicine, Division of Immunology/Allergy Section, 231 Albert Sabin Way, Cincinnati, Ohio, USAFull list of author information is available ... pain.Typically the extremities, genitalia, trunk, gastrointestinal tract, face, and larynx are affected by attacks of swelling.Laryngeal swelling carries significant risk for asphyxiation. The disease...