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Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis" pot

Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis

Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis" pot

... technology has been,theoretically, to increase the safety and com-pleteness of surgery in addition to increasing the confidence of the surgeon. This accounts for the increasing numbers of health ... state of the art in endoscopic sinussurgery includes many recent innovations. Prob-ably the most fundamental change in sinus surgeryhas been the adaptation of rigid endoscopes for use in the ... sur-gical intervention would include the presence of anatomic abnormalities that could predispose the Rhinitis and Sinusitis Advances in the Surgical Management of Chronic RhinosinusitisErin D....
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Báo cáo y học: "Developments in the scientific understanding of rheumatoid arthritis" pot

... knowledge of the pivotal role played by cytokines during the effector stages of human disease; has been instrumental in clarifying the place of cytokines in the maintenance and chronicity of inflamma-tion; ... onidentifying mechanisms upstream of the synovial inflamma-tion. The most promising finding paving the way for potentialpreventive therapy relates to the more recent concept of asystemic prodromal ... citrullination may play a role in the initiation of an immune response. The finding that Asian RApatients are more likely to have inherited an enzyme variant of PADI-4 (peptidylarginine deiminase...
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Báo cáo y học: " Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets" pps

... surprising considering the components of the ACR criteria. One of the criteria is the presence of erosions on the radiographs of hands and wrists. In the early phases of RA only 13% of the patients ... Additionally, erosions often initiallypresent in the small joints of the feet, and appear in the smalljoints of the hands at a later point in the disease course [6].Also, rheumatoid nodules are very ... Further evaluation of the effect of genetic variation in MMP3 on the level of joint damage in RA is thereforerequired. The increasing comprehension of the role of genetics in disease outcome in...
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Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot

Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot

... respectively. Binding data was obtained byanalytical ultracentrifugation using the direct binding assay as des-cribed in Experimental procedures. Inset: Linearized plot of the binding data for ... raises the possibility that any one or acombination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity tofractionate lipid emulsions into relatively ... affinity (Kd) for the large lipidparticles, are notably distinct in their maximum bindingcapacities (Table 2). In particular, the binding footprintfor the apoE4 isoform, corresponding to...
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Báo cáo y học: "Developments in the clinical understanding of osteoarthritis" docx

... the synovium, in ligaments especially near their insertions, in bone, in muscle, and in the outer third of the meniscus in the knee. In an unusual study in which the lead investigator became the study subject ... providednew insights into how OA may be successfully managed. The symptoms of osteoarthritis: pain andinstability The pain of OA is activity-related, with pain coming ongenerally only when a person ... not the only symptom of OA experienced by patientswith knee and hip OA. They also frequently experience asensation of instability or buckling. The most commonsymptom is one of shifting or instability...
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Báo cáo y học:

Báo cáo y học: "Developments in the clinical understanding of rheumatoid arthritis" ppt

... consequence of the activation of many cell populationsand, ultimately, of the upregulation of proinflammatory cyto-kines [19,20]. By whichever means they themselves becomeactivated, they induce ... 1Composite indices are the best depicters of disease activity. The degree of disease activityat the start of a disease-modifying therapy is amajor determinant of the disease activityattainable in ... contrasting their increase in osteoarthritis [89]. Likewise, employment rates andemployability increase in the course of effective therapy [49],suggesting the resurrection or maintenance of the...
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Báo cáo y học: " Developments in the scientific understanding of lupus" pot

... responses. Furthermore, immune complexes of ANAscan drive the production of proinflammatory cytokines, inducing the ‘interferon signature’, and intensifying disease. Together, thesefindings point to ... entirety of the immune system. Some of these maybe genetically determined, whereas others arise secondarily in response to events such as infection. Not surprisingly,delineation of these disturbances ... pathways suchas transfection or DNA-binding proteins [11,12]. Within the context of SLE, these findings suggest that moleculesinducing autoimmunity have intrinsic immunologic activity andmay serve...
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Báo cáo y học: "Developments in the scientific understanding of osteoarthritis" doc

... orinhibitors of inflammatory cytokines.Degeneration of articular cartilage in osteoarthritis:inflammation The role played by inflammatory cytokines and mediatorsproduced by joint tissues in ... hypertrophy and hyperplasia, withan increased number of lining cells, often accompanied byinfiltration of the sublining tissue with scattered foci of lymphocytes [68]. Synovitis is often localized ... deletion of either interleukin-1beta, inter-leukin-1beta-converting enzyme, inducible nitric oxide syn-thase, or stromelysin 1 accelerates the development of kneeosteoarthritis in mice after surgical...
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Báo cáo y học: "Developments in the scientific understanding of osteoporosis" docx

... localregulation has increased over the past 10 years through the discovery of the canonical Wnt signaling pathway. The Wntfamily of glycoproteins represents a major signaling pathwaythat is involved in cellular ... as an inflammatory arthritis in which jointinflammation results in bone deterioration. In RA, the pro-inflammatory cytokine TNF-α is critical in driving inflammatorydisease. TNF is mainly produced ... serotonin synthesis in enterochromaffincells in the duodenum. Serotonin appears to inhibit osteo-blast proliferation by binding to its receptor, 5-hydroxy-tryptamine receptor 1B, on the osteoblast...
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Báo cáo y học: "Developments in the clinical understanding of lupus" pot

... bytype I IFN.A randomized placebo-controlled study of the withdrawal of hydroxychloroquine treatment in clinically stable SLE patientswas published in 1991 by the Canadian HydroxychloroquineStudy ... JL,Cividino A, Danoff D, Osterland CK, Yeadon C, Smith CD: Along-term study of hydroxychloroquine withdrawal on exacer-bations in systemic lupus erythematosus. The CanadianHydroxychloroquine Study ... pathophysiology through theircapacity to focus relevant antigens for presentation to T cells,by production of cytokines, through their role in organizing the anatomy of the germinal centers and other...
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