... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs,thereby releasing the nucleocapsid into the lumen of these vesi-cles. Then, the capsid uses these intra-endosomal ... milddevelopmental delay. The protein defective in this disorder is alsoa NHEJ protein. The distinct clinical features of the patients willbe discussed in the context of the protein function.3.4 Diabetes, ... miceinvestigated have no detectable NK/NKT-cell population in theirspleen. In addition, production of the cytokines interferon c,interleukin-6 and interleukin-2 is clearly different in wild...